by the manager because of her untidy

Ngày tải lên: 05/09/2013, 10:17

... network involving other residues and solvent molecules. An unex- pected result was the extremely high thermostability of Mn[G77Q] and the very low thermostability of Fe[A141Q] (Fig. 5). Each of these mutants ... SODs is not governed by one or even two residues, but is most likely accomplished by the concerted effects of a combination of key residues. Further analysis of these and other mutant SODs is currently ... whether in vivo or in vitro [3,4]. Second, specificity of the reaction is determined by the metal ion: the enzyme is active only with the ÔcorrectÕ metal. Although, in the complete absence of the ÔcorrectÕ...

Ngày tải lên: 21/02/2014, 01:21

... estimate of the effectiveness of the linker in modulating the ribonucleo- lytic activity and, in essence, provides a measure of the therapeutic index of a ribonuclease zymogen. For the 1C zymogen, the ... produce the NS3 protease [48], DNA encoding 12 residues of the NS4A protein of HCV and a flexible Gly- Ser-Gly-Ser tether was inserted upstream of the NS3 gene. The protein encoded by the resulting ... and the K d value for the pRI complex with unactivated 1C zymogen was therefore estimated to be > 1 lm [37]. The lack of affinity of unactivated 1C zymogen for pRI puts it in the range of the...

Ngày tải lên: 07/03/2014, 11:20

... about the faith of zinc bound in Cd 5 Zn 2 -MT2 after the addition of NO, the amount of cadmium is reduced at this rather extreme NO Fig. 1. Wavelength and time scans of the CD of MT2 in the presence and ... by nitric oxide. The decay occurs in the first 10 min after the addition of NO as observed by monitoring the CD at the maximum of the charge transfer band at 260 nm (Fig. 1B). The lower molar ellipticity ... was equili- brated for at least 20 min prior to the start of the NMR acquisition. The same experiment was performed in the presence of GSH, whereby the GSH concentration was 1m M for samples containing...

Ngày tải lên: 07/03/2014, 15:20

... of lowering the interest rate according to the policy adopted by the Conference of Bankers at the beginning of the year, the State Bank preserved the status quo on the grounds that the inflation ... noted that the interest rates of all state-owned banks are nearly same. On the other hand, the utility package offered by the banks to the investors mainly includes the low cost of capital, ... Part 1, the higher the interest is, the lower GDP and the higher the inflation rate is. However, in almost all economies, there are always objectives of higher GDP growth rate and lower the inflation...

Ngày tải lên: 15/03/2014, 01:20

... distribution of spots. The lighter a particular area of the image is, the higher the density of random spots, or “events”, the algorithm generates in this area. Fig. 9 shows the output of the program used ... sciences and the rise of modernism in the arts in the early twentieth century represent two facets of the same profound shift in the cultural evolution of humankind. The uneasiness many of us experience ... with the splines moving freely along the nails, allows the total bending energy of the spline to settle down at its minimum [30]. I marked the contours of two human profiles facing each other...

Ngày tải lên: 16/03/2014, 15:20

... complex that supports the loading of two RuvB ring helicases on opposing duplexes and of a dimer of RuvC endonuclease on the other face of the junction in the space between the RuvB rings [ 7,8]. ... resolvasome complex requires the binding of RuvA to one face of the junction and RuvC to the other [8,9]. Complexes formed by the loading of both RuvA and RuvC on a synthetic junction can be detected using ... blocking the access of other junction process- ing enzymes such as RecG [24]. Expression of MpRuvA also reduced survival of the ruv + AB1157 strain (Fig. 6B). However, the effect was rather modest...

Ngày tải lên: 17/03/2014, 17:20

... 7). These results may be of physiological relevance because they indicate that the formation of the ternary complex is correlated with the level of cal- pastatin present in the cytosol. By quantification ... areas of the peaks were normalized on the basis of the amount of protein loaded on the column. The val- ues reported are the arithmetical mean ± SD of three different experiments. Degradation of ... hindrance and a reduction in the catalytic efficiency of the protease. Thus, the recruitment of calpain in the HSP90–NOS complexes reduces the extent of the proteolysis of these two proteins. We have...

Ngày tải lên: 23/03/2014, 07:20

... associated with the passage of time during the year. This is offset against the other cost items and is generally the expected long- term rate of return on assets multiplied by the beginning of year ... percent of the greater of the plan’s PBO or MRVA. The total of the above pieces of the NPPC can produce a negative expense, which appears as income on a company’s financial statements. The accrued ... equal to the last date of the fiscal year. 6 As of that date, the company sets assumptions and gathers the participant data used to measure its obligations and determines the fair value of assets...

Ngày tải lên: 29/03/2014, 14:20

Ngày tải lên: 30/03/2014, 15:20

Ngày tải lên: 31/03/2014, 21:21

Ngày tải lên: 03/06/2014, 00:48

Ngày tải lên: 22/06/2014, 22:20

Ngày tải lên: 22/06/2014, 22:20

... is to tackle the cost of the system by supporting many more people into work. Alongside the introduction of the Work Programme, we believe there is a strong case for reforming the system as ... creates the possibility that the level of conditionality would be determined, not by the benefit received, but by the reason for receiving benefit, creating a single progression to higher levels of ... permission from the copyright holders concerned. ISBN: 9 7 8 0 1 0 1 7 9 1 3 2 8. Printed in the UK for The Stationery Of ce Limited on behalf of the Controller of Her Majesty’s Stationery Of ce. ID:...

Ngày tải lên: 06/03/2014, 08:20

Ngày tải lên: 11/06/2014, 14:18

Ngày tải lên: 04/10/2012, 10:02

... Interestingly, when there are three or more children in the household, men are found to work even fewer hours around the house than before the appearance of the third child. Whereas women's ... men maintain approximately the same number of hours of unpaid work as in childless households, but the number of hours women work in the home rises to 52 per week, much of it, on doubt, due to ... this task. model answer: The diagram reveals that the number of hours per week spent in unpaid work is unequally distributed between men and women. In households where there are no children, women...

Ngày tải lên: 04/10/2012, 10:02

Ngày tải lên: 05/09/2013, 08:40