breaking localization and nicolai mapping in matrix models
Báo cáo khoa học: Characterization, localization and possible anti-inflammatory function of rat histone H4 mRNA variants potx
Ngày tải lên :
16/03/2014, 13:20
... distributed, being also abundant in endocrine, neuroendocrine and central nervous system tissues such as the pituitaries, the spinal cord and the brain Both mRNAs were also detected in AMs, and their ... C-terminal H4 and HN related-peptides, were shown to be present in nonreplicating and terminally differentiated rat AMs (Fig 1B) [42] Synthesis, storage, processing and release of C-terminal histone ... regulatory mechanisms, in addition to producing the extracellularly acting antiinflammatory peptides, remains to be investigated In conclusion, a growing body of evidence indicates that various...
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Báo cáo y học: "4th meeting of the EU research network EUROME: From the identification of genes and cellular networks in murine models of arthritis to novel therapeutic intervention strategies in rheumatoid arthritis, London, UK, 9 March 2004" pot
Ngày tải lên :
09/08/2014, 01:23
... (extracellular matrix) More importantly, knocking out the expression of gelsolin, an actin-binding protein with filament-severing properties found downregulated in RA, resulted in mild exacerbation ... expression of antiapoptotic proteins Bcl-2 and members of the inhibitor of apoptosis family (cIAP-1, XIAP and survivin, which directly bind to and inhibit caspases), was strikingly reduced Dr Brigitte ... cytosis by binding the complement inhibitor factor H (and in some cases, also the factor H-like protein 1) to its surface Binding is mediated by two types of plasmidencoded protein, class I (20...
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Checking the comformance between the implementation and PSM specifications in component models
Ngày tải lên :
25/03/2015, 09:45
... following files: Enterprise Beall class: Implements the methods defined in the business interư face and any life cycle callback methods; Business Interfaces: The business interface defines ... facilitate the maintenance and upgrading of systems bv customizing and replacing their components 2.2 C o m p o n e n t-b a s e d s o ftw a re e n g in e e rin g 2.2.2 Com ponent a) D e fin itio n ... Compoiumt are defined by their interfaces, and in tlie most general cases, can be thought of as having two related interfaces, as show in Figure 2.2 A provides interface defines the services...
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Appearance based mobile robot localization and map building in unstructured environments
Ngày tải lên :
11/09/2015, 14:22
... on localization and map-building in an unknown indoor environment Our approach aims to solve the problem of localization and/ or simultaneous localization and map-building (SLAM) in large indoor ... among landmarks locally The difference between the Kalman filter and the information filter is that the Kalman filter maintains a covariance matrix whereas the information filter maintains the inverse ... navigation in large scale indoor environment • To develop an algorithm that performs localization and/ or simultaneous localization and map-building in realistic indoor environment (SLAM) • To initiate...
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Báo cáo khóa học: Acharan sulfate, the new glycosaminoglycan fromAchatina fulica Bowdich 1822 Structural heterogeneity, metabolic labeling and localization in the body, mucus and the organic shell matrix docx
Ngày tải lên :
16/03/2014, 16:20
... acetate buffer (pH 5.5) containing 40 mg papain in the presence of mM EDTA and mM cysteine, and incubated at 60 °C for 24 h GAGs were isolated and purified from the papain-digested mucus by sequential ... fat-free, dried snail was cut into very small pieces that were suspended in sodium acetate buffer (pH 5.5) containing 40 mg papain in the presence of mM EDTA and mM cysteine, and incubated at 60 °C for ... commonly eat it Interestingly, heparin-binding adhesion proteins were reported to be expressed in adult forms of Strongyloides venezuelensis [28] As Achatina fulica may act as an intermediate host...
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Báo cáo y học: "PKC and PKA Phosphorylation Affect the Subcellular Localization of Claudin-1 in Melanoma Cells"
Ngày tải lên :
03/11/2012, 11:17
... for the regulation and localization of claudin expression It has been shown that protein kinases such as Protein Kinase A (PKA) and Protein Kinase C (PKC) can phosphorylate claudins (6,7) Phorbol ... and localization 99 Indeed, a study shows that increasing β-catenin increases the expression of claudin-1 in colorectal cancer cells, and that claudin-1 expression is increased in more aggressive ... claudin-1 does not increase melanoma cell motility We have previously shown that increasing the levels of CLDN-1 increases the invasion of melanoma cells (4) To determine if the increase in claudin-1...
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Tài liệu Báo cáo Y học: Regulated expression and intracellular localization of cystatin F in human U937 cells pptx
Ngày tải lên :
21/02/2014, 01:21
... heavy and a light fraction containing mitochondria and various cell organelles, and a supernatant containing the smallest cellular vesicles Cystatin F, cystatin C and protein contents in the ... Cm-papain Lanes and contain 30 and 10 ng insect cell-derived recombinant cystatin F, respectively The two bands seen represent cystatin F with one (B) and two (A) carbohydrate side chains [5] ... cathepsin L [5,6], as well as mammalian legumain [10] These enzymes are known to be involved in invariant chain [8] and antigen [11] processing, respectively Our present results showing a distinct intracellular...
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Tài liệu Báo cáo khoa học: "Dialogue and Understanding Development Environment, mapping Business Process Models to Information State Update dialogue systeDialogue and Understanding Development Environment, mapping Business Process Modelsms" pptx
Ngày tải lên :
22/02/2014, 02:20
... create and modify spoken dialogue systems, starting with a definition of a Business Process Model (e.g banking, cinema booking, shopping, restaurant information) and ending with a working system ... Dialogue and NLP Engine] www.grahamtechnology.com Staffan Larsson and David Traum 2000 Information state and dialogue management in the TRINDI Dialogue Move Engine Toolkit Natural Language Engineering, ... strategies) are handled by the core DM Values for constraints on transitions and branching in the BPM (e.g present insurance option if the user is business-class) are compiled into domain-specific parts...
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Báo cáo khoa học: Analysis of Lsm1p and Lsm8p domains in the cellular localization of Lsm complexes in budding yeast ppt
Ngày tải lên :
07/03/2014, 02:20
... importance of residues proposed to be involved in RNA binding and complex formation, and of the C-terminal region for the func- Lsm1 and -8 domains involved in localization tional competence of the ... proteins, consisting of a five-stranded anti-parallel b sheet which is involved in intersubunit and protein–RNA contacts [29,33,34] Crystal structures and cross-linking data have shown that RNA-binding ... Lsm1 and -8 domains involved in localization A B C D Fig Effects of mutations in Lsm8p on its nuclear localization (A) Lsm8p C-terminal domain mutations (B) Lsm8p N-terminal domain mutations and...
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Báo cáo khoa học: Identification, subcellular localization and functional interactions of PilMNOWQ and PilA4 involved in transformation competency and pilus biogenesis in the thermophilic bacterium Thermus thermophilus HB27 ppt
Ngày tải lên :
07/03/2014, 12:20
... fatty acylation and, thereby, be involved in membrane anchoring of the pilin Since PilA4 is similar to the meningococcal pilin and contains several central serine residues, it is tempting to speculate ... presence of PilQ in inner membranes is interesting, because secretin-like proteins of type IV pili and type II protein translocation machineries are known to form ring-like structures in outer membranes ... proteins J Rumszauer et al N-terminal domain of PilQ, and the colocalization of PilQ with PilW in inner and outer membranes and the results from the pilW and pilQ mutant studies, it is tempting...
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Báo cáo khoa học: "Combining Statistical and Knowledge-based Spoken Language Understanding in Conditional Models" pptx
Ngày tải lên :
08/03/2014, 02:21
... probabilistic models for segmenting and labeling sequence data ICML Nocedal, J and S J Wright 1999 Numerical optimization, Springer-Verlag Povey, D and P C Woodland 2002 Minimum phone error and I-smoothing ... speech recognition IEEE International Conference on Acoustics, Speech, and Signal Processing Collins, M 2002 Discriminative Training Methods for Hidden Markov Models: Theory and Experiments with ... training algorithms for conditional models In most cases, CRF training is more accurate, however, perceptron training is much faster References Bahl, L., P Brown, et al 1986 Maximum mutual information...
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Bell & Howell Information and Learning 300 North Zeeb Road, Ann Arbor, MI 48106-1346 USA 800-521-0600UMI.The Potential of Soil Survey Data in a Quantitative Evaluation of Surficial Geology Mapping in Northern Maine by Rosalia EvansThesis submitted t pptx
Ngày tải lên :
08/03/2014, 23:20
... geology mapping is time consuming and expensive, and unfortunately the last three decades have seen a decrease in basic geologic mapping due to the prevailing political climate in which cutbacks in ... compiled employing conventional mapping techniques Conventional mapping techniques involve extensive research and observation in the field Conventional soil mapping data for soil surveys include: steepness, ... drained Winooski Series (0.3 percent) formed in silty and fine sandy flood-plain deposits The sediments were derived mainly from shale and slate Made Land (0.005 percent), a miscellaneous land...
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Báo cáo " Research on organizing spatial production of economic models for agro - fisheries and processing industry in Diem Dien Town, Thai Thuy District, Thai Binh " doc
Ngày tải lên :
22/03/2014, 12:20
... resources and protecting environment One of typical marine economic models that has been organized and 39 Training technical staff in charge of cultivating and processing Boiling raw material in alkali ... Bleaching alkaliboiled product Supplying material equipment, services of producing consuming and exporting Cooking bar jelly between 200 - 210 minutes Separating product drying, packing and consuming ... marine industry 37 3.3 Processing industry, handicraft and service 3.3.1 Food processing Capacity of processing industry consumed about 50% of aquaculture production output The main processing...
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Báo cáo khoa học: Functions and cellular localization of cysteine desulfurase and selenocysteine lyase in Trypanosoma brucei pot
Ngày tải lên :
22/03/2014, 21:20
... resulted in stable integration and phleomycin-resistant transfectants were obtained by limiting dilution Induction of double-stranded RNA synthesis upon the addition of tetracycline indeed resulted in ... against cytosolic enolase and mitochondrial prohibitin (PHB1) Localization of SCL protein We used a tagging strategy to analyze the intracellular localization of this protein A hemagglutinin ... respectively (B) Immunolocalization of the TAP-tagged SCL protein in procyclic T brucei (a) 4¢,6diamidino-2-phenylindole-staining of nuclear and kinetoplast DNA; (b) mAb mAb56 against the mitochondrial...
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Báo cáo khoa học: LRRK2 in Parkinson’s disease: in vivo models and approaches for understanding pathogenic roles pdf
Ngày tải lên :
23/03/2014, 04:20
... model systems, including lower eukaryotes and invertebrates, in order to obtain clues for building important hypotheses The rapidity and efficiency of in vivo studies in many nonmammal models have ... understanding pathogenic roles Z Yue function [5] LRRK2 also contains armadillo-like repeats, LRR, kinase and WD40 domains [6] In vitro biochemical analysis demonstrates that LRRK2 contains kinase and ... illustration of domain structures and alignment for LRRK2 and LRRK2 structure-related proteins ANK, N-terminal ankyrin repeat domain; DEP, Dishevelled, EGL-10, pleckstrin domain; GEF, guanine-exchange...
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Báo cáo khoa học: Liver receptor homolog-1 localization in the nuclear body is regulated by sumoylation and cAMP signaling in rat granulosa cells docx
Ngày tải lên :
23/03/2014, 06:20
... target proteins in vivo The attachment of SUMO may result in diverse effects on the substrate protein, including cellular and subnuclear localization [20,21], changes in stability [22] and transcriptional ... triple-mutations with three arginine substitutions at 173, 213 and 289 or 289, 329 and 389 resulted in some LRH-1 localization in the nucleoplasm and a reduced concentration in nuclear bodies (Fig 5D,E) ... synthesized in vitro and incubated with recombinant SUMO-1 protein, E1 (SAE1 ⁄ SAE2) and E2 (UBC9) enzymes Upon separation of the reaction products by SDS ⁄ PAGE, a slowermigrating band at approximately...
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Báo cáo khoa học: Characterization of Trypanosoma brucei PEX14 and its role in the import of glycosomal matrix proteins pptx
Ngày tải lên :
23/03/2014, 17:21
... on matrix protein import ALD is shown in green, and GAPDH in red (C) Effects of TbPEX14 depletion on glycosomal matrix and membrane proteins in procyclic trypanosomes ALD is shown in green, and ... synthesized proteins in the cytosol due to the inability to import matrix proteins by the fraction of growing and dividing glycosomes The miscompartmentation of PTS-1 and PTS-2 proteins (GAPDH and ALD, ... no membrane-spanning domains in PEX14 have been unambiguously identified and it was observed in mammalian cells and S cerevisiae that both the N-terminal and the C-terminal domain are at the cytosolic...
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Báo cáo khoa học: Expression, localization and potential physiological significance of alcohol dehydrogenase in the gastrointestinal tract pdf
Ngày tải lên :
23/03/2014, 17:22
... [9] and differences in diet, intestinal flora, etc Role of gastrointestinal ADH in retinoid metabolism The expression of ADH1 and ADH4 in certain cell layers of gastrointestinal tissues, and its ... Retinoic-acid-binding protein in normal and neoplastic human esophagus Cancer 54, 308–311 Inagami, S & Ong, D.E (1992) Purification and partial characterization of cellular retinol-binding protein, ... cells lining intestinal villi, in contrast to crypts of Lieberkuhn, which stained weakly ¨ (Fig 4C) Connective tissue, lamina propia, and muscularis mucosae were not stained Localization of ADH in...
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Báo cáo khoa học: Subcellular localization of yeast Sec14 homologues and their involvement in regulation of phospholipid turnover pptx
Ngày tải lên :
23/03/2014, 18:20
... nucleus and in the cytoplasm [48] Ó FEBS 2003 Fig Phosphatidylcholine turnover in strains overexpressing Sfhproteins Yeast cultures were grown overnight at 37 °C in Ins–/Cho– medium containing lCiÆmL)1 ... formation, indicating that Sec14p and the two homologues act as inhibitors of Plb1p in vivo This observation explains at least in part the low Plb1p activity in wild-type cells Interestingly, the inhibitory ... to pouring plates as described by van den Hazel et al [11] Chemically defined synthetic media lacking inositol and choline (Ins–/Cho–) or supplemented with 75 lM inositol and mM choline (Ins+/Cho+)...
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Báo cáo khoa học: Perturbation of membrane microdomains in GLC4 multidrug-resistant lung cancer cells ) modification of ABCC1 (MRP1) localization and functionality docx
Ngày tải lên :
30/03/2014, 09:20
... flask-shaped invaginations of the plasma membrane that originate from the presence of caveolin family proteins Among the three isoforms, caveolin-1, caveolin-2 and caveolin-3, caveolin-1 is the predominant ... shown), and strictly analogous data were obtained MRP1, GM1 and caveolin-1 distribution within membrane fractions In order to determine the effect of MbCD on the integrity of rafts and the localization ... among the resistance factor, kinetics of uptake, and kinetics of the Pglycoprotein-mediated efflux of doxorubicin, daunorubicin, 8-(S)-fluoroidarubicin, and idarubicin in multidrugresistant K562 cells...
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