brain damage in babies due to lack of oxygen
Báo cáo khoa học: Enhanced sensitivity to hydrogen peroxide-induced apoptosis in Evi1 transformed Rat1 fibroblasts due to repression of carbonic anhydrase III docx
... Enforcedexpression of caIII in Evi1-expressing Rat1 cells reverts the phenotype,restoring H2O2resistance. Together these data show that Evi1 repressestranscription of caIII gene expression, leading to increased ... regulated and induced by Evi1; GATA2being the best characterized [6,33]. Inspection of the)1485 ⁄ +55 rat nucleotide sequence for Evi1 protein-binding sites with matinspector software revealed ... observed in Rat1 cells.Inspection of the caIII )1485 ⁄ +55 promoter regionwith matinspector software showed several potentialbinding sites for E2F family proteins, but not for any of the other...
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Báo cáo sinh học: "Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke" pot
... glutamate-induced excitotoxicity. The effect of neuroserpin onreducing this tPA-induced damage in the brain has beenstudied, and both the over expression of neuroserpin [3]and neuroserpin treatment ... closed.Theabsolutedifferencebetweenbasaland24hoursneuroserpin levels was defined as neuroserpin decrease.All determinations were carried out in a laboratoryblind to the clinical outcome and neuroimaging findings.EndpointsThe primary endpoint ... Neuroserpin was usedas a continuous variable since there was a linearity of theodds ratios for outcome. T he influence of neuroserpindecrease at 24 h on serum levels of molecular markers of brain injury...
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báo cáo hóa học:" Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke" pdf
... closed.Theabsolutedifferencebetweenbasaland24hoursneuroserpin levels was defined as neuroserpin decrease.All determinations were carried out in a laboratoryblind to the clinical outcome and neuroimaging findings.EndpointsThe primary endpoint ... glutamate-induced excitotoxicity. The effect of neuroserpin onreducing this tPA-induced damage in the brain has beenstudied, and both the over expression of neuroserpin [3]and neuroserpin treatment ... obtained after investigating neuroserpineffects using an in vitro model of brain ischemia [40].The information reported here regarding b iomarkersmight be relevant to evaluate the utility of...
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Tài liệu A REVIEW OF INDOOR AIR POLLUTION AND HEALTH PROBLEMS FROM THE VIEWPOINT OF ENVIRONMENTAL HYGIENE: FOCUSING ON THE STUDIES OF INDOOR AIR ENVIRONMENT IN JAPAN COMPARED TO THOSE OF FOREIGN COUNTRIES pptx
... phthalates were detected predominantly in indoor air samples.93)The dominant path of phtha-lates intake was the ingestion of foodstuffs com-pared to inhalation of indoor air by children.94)n-Tetradecane ... reviewed according to the history of sick buildings. Next, the factors concerningindoor air quality are indicated, and then measures to combat these problems are considered to improve the indoorenvironment. ... forpeople studying in schools, working in of ces andliving in residences. Indoor air quality plays an im-portant role in the health of residents. Many f actorsare associated with polluted indoor air...
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báo cáo hóa học: " Interleukin-1alpha expression precedes IL-1beta after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues" pdf
... contributor to the worsening of acute brain injury [1]. In particular two pro-inflammatory members of the IL-1 family of cytokines, IL-1α and IL-1β, are considered the major effectors of injury, ... contributors to ischemic brain injury. However, there is very little evidence that IL-1 expression occurs at the protein level early enough (within hours) to influence brain damage after stroke. In ... stroke induced by MCAo. Such a study was required since strategies aimed at inhibiting inflammation in the brain will be dictated by the nature of the inflammatory mediators produced. We first investigated...
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Scientific report: "Loss of land due to construction of industrial zones and rural employment" potx
... Rondinelli, 1987). The success of IZs in term of employment generation can be explained that their field of production is based on labor intensive industries which find in early stage of industry ... administrator. The main functions of IZs Management Board are managing, monitoring enterprise business activities, and reducing administrative procedure for enterprises in order to attract investment ... working on farm, 18 moves to work as factories worker, 33 as hired labor for construction work in Que Vo IZ, and 15 of them run their own business of buying and selling in the village. Half of...
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Children’s Health Deficits due to Diarrhoea: Effects of Water Supply and Sanitation Systems in Slums with Different Water Logging Conditions
... NCDHouseholds in each community ( % )( f )Households using overhead hanging latrineHouseholds using sanitary latrineHouseholds using unsanitary latrineHouseholds using no latrine at allHand washing ... resulting in stagnant water and drainage problems (JICA 1990; JICA 1987; SWMC 1997). The inadequate Address correspondence to Kei NISHIDA, Interdisciplinary Graduate School of Medicine and Engineering, ... impact of water logging on diarrhoeal incidence in Dhaka City, and how household and individual factors interact with this impact are of utmost necessity in finding prime locations for slum development...
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Báo cáo khoa học: Post-ischemic brain damage: the endocannabinoid system in the mechanisms of neuronal death ppt
... followingtoxic administration of kainic acid [74,95], suggestingthat brain- derived neurotrophic factor may be anotherimportant mediator of the neuroprotective effects of CBs.CB receptor-independent ... Moro MA & Lizasoain I (2006)Characterization of the neuroprotective effect of thecannabinoid agonist WIN-55212 in an in vitro model of hypoxic-ischemic brain damage in newborn rats.Pediatr ... neurons.Concluding remarksThe great deal of knowledge accumulated in the pastthree decades on the mechanisms underlying damage in icted to the brain tissue by cerebral ischemia hasfailed to translate into...
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Báo cáo khoa học: Post-ischemic brain damage: pathophysiology and role of inflammatory mediators ppt
... K& Gearing A (2001) Immunohistochemistry of matrixmetalloproteinases in reperfusion injury in rat brain: activation of MMP-9 linked to stromelysin-1 andmicroglia in cell cultures. Brain Res ... into the brain paren-chyma. In ltrating leukocytes, as well as resident brain cells, includingneurons and glia, may release pro -in ammatory mediators, such as cyto-kines, chemokines and oxygen ... soluble proteins, including receptors and cytokines such as inter-leukin-1b. The present work reviewed the role of neuroinflammatorymediators in the pathophysiology of ischemic brain damage and their...
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Báo cáo khoa học: Mutants of Saccharomyces cerevisiae deficient in acyl-CoA synthetases secrete fatty acids due to interrupted fatty acid recycling docx
... state of the cells To gain further insight into the correlation of growthphase of the culture and the direction of fatty acidtransport, we investigated the possibility of manipulat-ing the ... More interestingly, the pool of free fatty acids contained 18:2 as well; indicating arelease of formerly lipid bound fatty acids into thispool (Fig. 4B,C). Moreover, the ratio of the sum of allnatural ... concentration in themedia did not reach a stable plateau. Instead, the totalamount of fatty acids in the media started to declineduring the late exponential phase and continued to decrease during the...
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Báo cáo Y học: Human bile salt-stimulated lipase has a high frequency of size variation due to a hypervariable region in exon 11 pot
... fat-soluble vitamin esters and cholesterolesters in the small intestine. In some species, includinghumans, the gene is also expressed in the lactatingmammary gland and the resulting protein is a constituent of ... one case, a n insertion corres-ponding to the variation in molecular mass of the BSSLprotein found in milk from the respective woman. Fur-thermore, we f ound that 56%, out of 295 individualsstudied, ... onco-fetalprotein FAPP, is due to the s ame frequently occurringFig. 7. Comparison of the deduced amin o-acid sequences of the repeats in B SSL from the published sequence carrying 16 repeats...
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