... THE NATION TO ELIMINATE THE SUFFERING AND DEATH DUE TO CANCER 17 STRATEGY 1.4 — Identify and characterize the influence of the microenvironment on the chain of events that leads to cancer ... THE SUFFERING AND DEATH DUE TO CANCER 15 To ensure the best outcomes for all, we will work to: 5. Understand the Factors that Influence Cancer Outcomes 6. Improve the Quality of Cancer Care ... measurements of tumor marker levels may be a part of treatment follow-up to check for recurrence. THE NCI STRATEGIC PLAN FOR LEADING THE NATION TO ELIMINATE THE SUFFERING AND DEATH DUE TO CANCER...
Ngày tải lên: 15/03/2014, 00:20
... distribution of the world’s urban population and that of the urban population of each of the 14 regions are shown in Figure 1. To allow the most appropriate epidemiologic studies to be used for ... (CRA) as part of its ongoing Global Burden of Disease project. The burden of disease in terms of deaths and disability-adjusted life years (DALYs) was estimated for 26 major risk factors by age, ... therefore, to make assumptions concerning factors such as the transferability of risk functions, exposure of the population, and its underlying vulnerability to air pollution, while trying to ensure...
Ngày tải lên: 29/03/2014, 18:20
Scientific report: "Loss of land due to construction of industrial zones and rural employment" potx
Ngày tải lên: 06/08/2014, 18:22
báo cáo khoa học: "Expectation of variance due to mitochondrial genes from several mating designs" ppsx
Ngày tải lên: 09/08/2014, 22:22
Báo cáo khoa hoc:" Marathon related death due to brainstem herniation in rehydration-related hyponatraemia: a case report" docx
Ngày tải lên: 11/08/2014, 10:22
Báo cáo y học: "Bench-to-bedside review: Mechanisms and management of hyperthermia due to toxicity" doc
Ngày tải lên: 13/08/2014, 10:20
Báo cáo y học: "Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of the hepatitis C virus" pdf
Ngày tải lên: 14/08/2014, 08:20
Analysis and compensation of log_domain filter deviations due to transistor nonidealities
Ngày tải lên: 06/11/2012, 10:35
Children’s Health Deficits due to Diarrhoea: Effects of Water Supply and Sanitation Systems in Slums with Different Water Logging Conditions
... secondary contamination due to storage, as some of the storage tanks had been used for a long time without cleaning. However, hand washing practices appeared to contribute to DALYs lost and constituted ... thank Dr. Yoshitaka Matsumoto for his contribution to this study. We are grateful to Prof. Yasushi Sakamoto and Prof. Futaba Kazama for their scientific suggestions, to Rezina Ashraf, MBBS, who ... durations of morbidity (Murray et al. 2002). DALYs, due to premature mortality, are calculated using standard expected YLL from model life tables and, due to disability from age a to age (a...
Ngày tải lên: 05/09/2013, 10:15
Báo cáo khoa học: Mutants of Saccharomyces cerevisiae deficient in acyl-CoA synthetases secrete fatty acids due to interrupted fatty acid recycling docx
... activity of Fat1p alone was not strong enough to prevent the secretion of fatty acids upon combined deletion of FAA1 and FAA4. To allow for speculation about the biological role of the release of fatty ... 18:1 to 18:2 [25,26]. Due to the nature of this desaturase, the generated 18:2 was considered as marker for the pool of bound fatty acids. Therefore, the occurrence of 18:2 in the pool of free ... release of the fatty acids is rather unspecific. The direction of fatty acid transport is dependent on the metabolic state of the cells To gain further insight into the correlation of growth phase of...
Ngày tải lên: 07/03/2014, 05:20
WORKSHOP ON THE PREVENTION OF WATER POLLUTION DUE TO PIPELINE ACCIDENTS pot
... PCM) Programmed automatic ESD-Sequences (e.g. ESD-Pushbutton, Shut-Down due to Communication Failure) UN 4. 4. Pipeline Integrity Pipeline Integrity - - Design and Review of Design and Review of Safety ... and Terminology b) Purpose of (Pipeline) SCADA systems Integration of field equipment (e.g. actuator, sensor or pump) and small scale (unit) automation systems to the control centre computer ... and Review of Design and Review of Safety Integrity Level (SIL) Safety Integrity Level (SIL) 3. national regulatory authorities expect it from us as prudent operators 4. Allows us to focus testing...
Ngày tải lên: 15/03/2014, 16:20
ECONOMIC EVALUATION OF HEALTH IMPACTS DUE TO ROAD TRAFFIC-RELATED AIR POLLUTION pptx
... attributable to road traffic All the above mentioned restrictions for the assessment of health costs due to air pollution reduces the costs by a factor of 3.6 (in Switzerland) up to a factor of 9.1 ... population of Austria, France and Switzerland is subdivided into categories of exposure to different classes of pollution levels from a superposition of the mapping of ambient concentration of particulate ... does not try to assess the value of a specific life. What is being measured is the benefit of a risk reduction due to a lower level of air pollution leading to a decrease in frequency of the different...
Ngày tải lên: 15/03/2014, 20:20
Báo cáo khóa học: Noncytotoxic ribonuclease, RNase T1, induces tumor cell death via hemagglutinating virus of Japan envelope vector ppt
... envelope vector, makes the noncytotoxic RNase, RNase T1, cytotoxic to cancer cells. This cytotox- icity i s s tronger than that of onconase. Furthermore, this RNase T1 induces the apoptotic cell death ... that the effect of BSA/HVJ was due to HVJ while the cytotoxicity of RNase T1/HVJ was mainly due to ribonuclease a ctivity of RNase T1 internalized via the HVJ envelope vector. Effect of protamine ... ciated with the vector. Next, we investigated the effects of various concentra- tions of protamine s ulfate in the pretreatment of HVJ envelope vector (Fig. 2B). The cytotoxicity of RNase T1/ HVJ...
Ngày tải lên: 23/03/2014, 12:20
Báo cáo khoa học: Sendai virus N-terminal fusion peptide consists of two similar repeats, both of which contribute to membrane fusion ppt
... we detected a segment of 11 residues strikingly similar to the N-terminal fusion peptide. As shown in Fig. 1A, the segment ranging from residue 7 to residue 17 is similar to the segment 21–31. Interestingly, ... mixing ability of a peptide corresponding to the N-terminal segment of Sendai F 1 protein toward negatively charged LUV composed of PS [31]. As we wanted to determine the role of these mutations on ... increase in the size of the vesicles, confirming that the ability of the peptides to induce lipid mixing is the result of membrane fusion. In order to shed light into their mechanism of action, we analyzed...
Ngày tải lên: 23/03/2014, 21:21
Báo cáo Y học: Human bile salt-stimulated lipase has a high frequency of size variation due to a hypervariable region in exon 11 pot
... USA). To improve ampli®- cation of the extremely GC-rich repeats, betaine was a dded to each reaction to a ®nal concentration of 2 M (Sigma, St Louis, MO, U SA). A pair of primers, referred to as BSSL ... human hepa- toma cell line HepG2 also expresses a BSSL isoform of lower molecular m ass [ 40]. The cDNA sequence of t his isoform contained only one ÔrepeatÕ. The obvious question is, of course, ... epeated region of the BSSL gene makes i t tempting to speculate that FAPP is identical to a naturally occurring low molecular mass variant of BSSL. The characteristic FAPP epitope should then...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo khoa học: Enhanced sensitivity to hydrogen peroxide-induced apoptosis in Evi1 transformed Rat1 fibroblasts due to repression of carbonic anhydrase III docx
... differentiation and evasion of apoptosis [1]. Evasion of apoptosis has been observed in both haemopoietic and epithelial cells with a variety of agents and suggests that Evi1 is a survival factor. For example, ... Evi1 is a survival factor, protecting cells from apoptosis induced by a variety of agents. To determine if Evi1 also protects Rat1 cells from apoptosis, we treated our panel of cell populations ... increased sensitivity to H 2 O 2 -induced apoptosis Although previous studies have shown that Evi1 pro- tects cells from a variety of inducers of apoptosis, the effects of H 2 O 2 have not yet...
Ngày tải lên: 29/03/2014, 08:20