... from the onset of the first clinical event that was a clear manifestation of SSc (other than Raynaud's phenomenon) to the time of data collection All patients fulfilled the criteria proposed by the ... were the components of the logistic regression model for alveolitis The cut-off values of the dependent variables considered in the analysis were based on ROC curves and are reported in table The ... honeycombing involving up to 25% of the lobe, 3honeycombing involving 25–49% of the lobe, 4- honeycombing involving 50–75% of the lobe, 5- honeycombing involving > 75% of the lobe for interstitial score...
Ngày tải lên: 12/08/2014, 18:22
... proved the eon'eetness of the system with a rigor and explicitness that is unusual for the great majority of mathematical proofs A Survey of the System gtructure Storage Allocation In the classical ... in their homing position Each process blocked in the course of task execution relies on the other processes for removal of the barrier Essentially, the proof in question is a demonstration of the ... the value of the semaphore called "sem" by If the resulting value of the semaphore concerned is positive, the V-operation in question has no further effect; if, however, the resulting value of...
Ngày tải lên: 12/09/2012, 15:05
Developmentof the Microfinance system in Russia
... 4.5 millions of individual entrepreneurs); 90 % of the total number of establishments; 44 % of GDP; 45 % of employment Sources of financing Business partners, relatives or other people ... stimulation of goods and services production and distribution, and also for a mutuality of start-up enterprises in the acquisition of getting profits and a capital accumulation experience Main tasks of ... of Microfinance to stimulate efficiency access to the financial resources; to create work places; to grow of tax proceeds; to create a credit history for the further development of SMEs...
Ngày tải lên: 24/10/2013, 03:15
The Critique of the Morality System
... with the historical facets of his position, some with the philosophical, and some with both.4 What are the defining features of the morality system? At the end of Chapter 10 of Ethics and the Limits ... Kant, some of the most fundamental moral obligations concern the promotion of general ideals or ends such as our own perfection and the happiness of others The obligations of the morality system ... 66216 The Critique of the Morality System July 11, 2007 113 KANT AND THE MORALITY SYSTEM Now that we have a better idea of what Williams means by the morality system, ” what are we to make of his...
Ngày tải lên: 01/11/2013, 07:20
an overview of the financial system
... An Overview of the Financial System • Primary function of the Financial System is financial Intermediation • The channeling of funds from households, firms and governments ... shortage of funds (borrowers) • Direct finance vs Indirect finance 2-2 An Overview of the Financial System II 2-3 Structure of Financial Markets I Debt Markets • Short-term (maturity < year) – the ... expertise and taking advantage of economies of scale 2- Function of Financial Intermediaries III Risk Sharing • Create and sell assets with low risk characteristics and then use the funds to buy assets...
Ngày tải lên: 05/01/2014, 16:55
Tài liệu Color Atlas of Pharmacology (Part 12): Inhibitors of the RAA System ppt
... impair the pumping action of the heart, or when there is a threat of other complications The choice of drug is empirical If the desired effect is not achieved, another drug is tried Combinations of ... membranous sacs of the sarcoplasmic reticulum (SR); c) Ca2+ bound to the inside of the plasmalemma The plasmalemma of cardiomyocytes extends into the cell interior in the form of tubular invaginations ... Overview of Modes of Action (A) The pumping capacity of the heart is regulated by sympathetic and parasympathetic nerves (pp 84, 105) Drugs capable of interfering with autonomic nervous function therefore...
Ngày tải lên: 26/01/2014, 19:20
Tài liệu Báo cáo khoa học: Control of the coagulation system by serpins Getting by with a little help from glycosaminoglycans pptx
... the RCL of the serpin inserts into the major A b-sheet causing the protease to be rapidly translocated from the top to the bottom of the inhibitor [6] In the process, the structure of the protease ... polymers of serpins, where the insertion of another molecule’s RCL takes place [8] Both of these result in the irreversible inactivation (generally) of the serpins, and, in the case of the anticoagulant ... ‘crushed’ against the bottom of the inhibitor [7] In particular, this deformation of the protease affects the geometry of the catalytic triad, preventing the completion of catalysis beyond the acyl intermediate...
Ngày tải lên: 20/02/2014, 02:21
Tài liệu Báo cáo khoa học: "The Second Release of the RASP System" pdf
... account both of the probability of derivations yielding a specific relation and of the proportion of such derivations in the forest produced by the parser A weighted set of GRs from the parse forest ... general) level in the hierarchy The micro-averaged precision, recall and F1 score are calculated from the counts for all relations in the hierarchy The macroaveraged scores are the mean of the individual ... to some extent tune the parser to different genres without the need for retraining The current version of the grammar finds at least one parse rooted in S for about 85% of the Susanne corpus (used...
Ngày tải lên: 20/02/2014, 12:20
Tài liệu Báo cáo Y học: Presence and regulation of the endocannabinoid system in human dendritic cells potx
... marrow stem cells, are the most potent antigen-presenting cells of the immune system They play a central role in the initiation of primary immune response and in the enhancement of secondary immune ... the RNA content and cDNA synthesis in the different preparations Furthermore, the PCR primers for glyceraldehyde3-phosphate dehydrogenase and FAAH were selected on the basis of the sequence of ... one of the enzymes mostly involved in endocannabinoid inactivation The heterogeneous distribution of CB2 receptors among cells of the immune system suggests that these receptors might exert their...
Ngày tải lên: 22/02/2014, 07:20
Aging of the Respiratory System: Impact on Pulmonary Function Tests and Adaptation to Exertion pdf
... recoil of the lung (Fig 2) [9] The kyphotic curvature of the spine and the anteroposterior diameter of the chest increase with aging, thereby decreasing the curvature of the diaphragm and thus its ... Conversely, there is a progressive decrease in vital capacity to approximately 75% of best values Because of the increased stiffness of the chest wall, the age-related diminished elastic recoil of the ... intercept) and a decrease in the surface area of airspace wall per unit of lung volume beginning in the third decade of life The decrease in surface area of airspace wall per unit of lung volume approximately...
Ngày tải lên: 05/03/2014, 21:20
PROTOCOL ON THE STATUTE OF THE EUROPEAN SYSTEM OF CENTRAL BANKS AND OF THE EUROPEAN CENTRAL BANK pdf
... months of the publication of the decision or of its notification to the plaintiff or, in the absence thereof, of the day on which it came to the knowledge of the latter, as the case may be 14.3 The ... 17 of the Act concerning the conditions of Accession of the Czech Republic, the Republic of Estonia, the Republic of Cyprus, the Republic of Latvia, the Republic of Lithuania, the Republic of ... equal to the sum of: — 50% of the share of its respective Member State in the population of the Community in the penultimate year preceding the establishment of the ESCB; — 50% of the share of its...
Ngày tải lên: 06/03/2014, 10:20
Báo cáo khoa học: Unique features of the hemoglobin system of the Antarctic notothenioid fish Gobionotothen gibberifrons ppt
... and C mawsoni) However, the lack of a clear relationship with the Hb sequences of other nototheniid species suggests that in this case the evolution of the oxygen-transport system has occurred in ... species of the family Nototheniidae have one major and one minor Hb (Hb and Hb 2, 95% and 5% of the total, respectively) [2, 4,14] The two Hbs have the b-chain in common, with the exception of those ... cancels the contribution of the N-terminus to the Bohr effect These substitutions are also found in the two Hbs of G gibberifrons, characterized by the Bohr and Root effects However, these Hbs...
Ngày tải lên: 08/03/2014, 08:20
Paradoxical roles of the immune system during cancer development docx
... On the basis of classical theories of immune surveillance and more recent awareness of the tumour-promoting properties of innate immune cells, researchers are now investigating the efficacy of ... transplants is increased when there is a previous history of alcohol and tobacco use66,67 On the other hand, the RR for the most common non-viral-associated solid tumours of epithelial origin is decreased ... S1 (table)) These studies, together with the identification of tumour-associated antigens, have in part fuelled the development of antitumour immunotherapy approaches 68 Although these approaches...
Ngày tải lên: 15/03/2014, 01:20
The origin and evolution of the solar system woolfson
... Newton the basic structure of the solar system and the laws that govern the motions of the bodies within it have been well understood One central body, the Sun, containing most of the mass of the system ... for the origin of the solar system and their strengths and weaknesses are analysed The only theory to essay a complete picture of the origin and evolution of the solar system is the Capture Theory ... in gure 1.2 The rst of these is the longitude of the ascending node, ê, which is the angle between the ascending node and the rst point of Aires The second angle is the argument of the perihelion,...
Ngày tải lên: 17/03/2014, 13:35
manual on the application of the haccp system in mycotoxin prevention and control pdf
Ngày tải lên: 17/03/2014, 16:20
Disease of the Respiratory system in Children ppt
... Introduction The disease of respiratory system is one of the most frequent reasons for hospitalization of infants and children Basic knowledge of the development and functions of respiratory system ... infection →develop obstruction The right bronchus →direct continuation of the trachea; The left bronchus spreads out from the lateral surface of trachea; So foreign body →often aspirated into right ... accumulation of mucus →bronchiolar obstruction Walls of alveoli →thicken Alveoli are filled with inflammatory exudates →impairs the normal exchange of gases in the lungs Diminished ventilation of the...
Ngày tải lên: 22/03/2014, 09:20
Báo cáo khoa học: Modulation of the endocannabinoid system by focal brain ischemia in the rat is involved in neuroprotection afforded by 17b-estradiol pdf
... 18 mm from the carotid bifurcation, until mild resistance was felt, thereby indicating occlusion of the origin of the MCA in the Willis circle The silk suture was tightened around the intraluminal ... content of the metabolic enzyme FAAH was significantly reduced following h of MCAo, with or without h of reperfusion (Fig 3) The latter finding is consistent with the reduced activity of FAAH in the ... known to protect the brain against focal ischemia [35] In order to investigate the role of the endocannabinoid system in the neuroprotection afforded by estrogen, the effect of acute treatment...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: A novel pathway for sequential transformation of 7-dehydrocholesterol and expression of the P450scc system in mammalian skin pptx
... (Invitrogen), and the isolation of RNA followed the manufacture’s protocol The synthesis of first-strand cDNA was performed using the Superscript preamplification system (Invitrogen) Either lg of total ... investigation on the cutaneous expression of each of the components of the P450scc enzymatic system In addition, we tested reconstituted and mitochondrial P450scc systems for their ability to ... characteristic of 7-DHP (Fig 5) The H-NMR spectrum of the biotransformation product is in agreement with that of the chemically synthesized standard (Fig 5) and with data from the literature [41] Thus, the...
Ngày tải lên: 23/03/2014, 13:20
Who Pays? A Distributional Analysis of the Tax Systems in All 50 States docx
... EXECUTIVE SUMMARY The 2013 Who Pays: A Distributional Analysis of the Tax Systems in All Fifty States (the fourth edition of the report) assesses the fairness of state and local tax systems The report ... the “federal offset” For more on the federal offset, see page 11) • The average tax rate on families in the middle 20 percent of the income spectrum is 9.4 percent • The average tax rate on the ... just 0.1 percent of the income of the very best-off In other words, these excise taxes are 16 times harder on the poor than the rich, and times harder on middle-income families than the rich In addition...
Ngày tải lên: 23/03/2014, 20:20
Báo cáo Y học: A new siglec family member, siglec-10, is expressed in cells of the immune system and has signaling properties similar to CD33 docx
... digesting the fragment with HindIII and Bgl II and the plasmid with HindIII and Bam HI The fragment was ligated into the plasmid and the integrity of the insertion was validated by digesting the plasmid ... contributing to the phosphorylation of the wild-type siglec tail by Lck and Jak3 kinases By comparison, the mutation of the tyrosine at position 641 did not significantly affect the degree of phosphorylation ... final pH of 8.0 Siglec-10 –hIg was then dialysed against NaCl/Pi To construct the GST fusion of the siglec-10 cytoplasmic domain (GST– siglec-10cyto-wt) the cytoplasmic domain (KRRTQTE…VFQ) of siglec-10...
Ngày tải lên: 24/03/2014, 04:21