assessment of risks associated with cervical collar use and mri
Báo cáo y học: "High-molecular-weight hyaluronan – a possible new treatment for sepsis-induced lung injury: a preclinical study in mechanically ventilated rats" ppsx
... MIP-2 and TNFα mRNA and protein production with mechanical ventilation In a comparisonn between rats with and without LPS at the same tidal volume, rats with LPS showed increased MIP-2 and TNFα ... ventilation After hours of ventilation, animals were sacrificed and the left lung was fixed with formaldehyde, sliced and stained with hematoxylin and eosin LPS caused edema and inflammatory cell ... with rats without LPS treatment Pretreatment with HMW HA (1,600 kDa) decreased BAL neutrophils and the total lung neutrophil infiltrate with LPS The results were similar with the use of 35 kDa...
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báo cáo hóa học: " Interleukin 1 receptor antagonist knockout mice show enhanced microglial activation and neuronal damage induced by intracerebroventricular infusion of human β-amyloid" pdf
... with Aβ Representative photomicrographs of F4/80-positive microglia in the hippocampus of a D) WT mouse infused with Aβ, and E) IL1raKO mouse infused with Aβ Arrowheads point to microglia cell ... infused with vehicle or Aβ, and IL1raKO mice infused with vehicle experienced no mortality during the time period In contrast, Aβ-infused IL1raKO mice experienced a 50% mortality rate (6 of the ... was dissected and used for biochemical analysis A) Levels of the pro-inflammatory cytokine IL-1β were significantly higher in IL1raKO mice infused with Aβ compared to WT mice infused with Aβ B)...
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Báo cáo y học: " Reducing ventilator-induced lung injury and other organ injury by the prone position" ppt
... changes of interactions between the weight of the heart and underlying lung tissue in the supine and prone positions More novel approaches may be needed to explain the different intensities of apoptosis ... is known about the causes of programmed cell death in this situation One of the suggested mechanisms could be the increased systemic plasma levels of inflammatory mediators and proaptotic soluble ... perfusion between the supine and prone positions may explain the more protective effect of the prone position for the liver and the diaphragm than for the kidney and the intestine epithelial...
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Báo cáo y học: "Alveolar instability caused by mechanical ventilation initially damages the nondependent normal lung" ppt
... indicator of alveolar instability or of VILI Competing interests histologic analysis GN contributed to the design and development of the protocol, to data analysis and interpretation, and to writing of ... performed in accordance with the National Institutes of Health guidelines for the use of experimental animals in research The protocol was approved by the Committee for the Humane Use of Animals at our ... addition of 10 cmH2O PEEP prevented the development of alveolar instability for the entire experiment in both the nondependent and dependent lungs (Figures and 4, and Additional file 4) Mechanism of...
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(1) how learners approach learning, both in and out of classrooms, and (2) the kinds of strategies and cognitive processing they use in second language acquisition
... range and the frequency of strategies use between learners of different levels, favoring professional linguists and learners with higher level of proficiency Research in Asia, such as in Thailand ... powerful impact of learning strategies on the learning and teaching of foreign and second language Good choice and use of learning strategies would help learners become more independent and autonomous ... understanding of individual learner differences in general and of gender differences in learning in particular is of great importance Proper adjustment and adaptation from the side of the teachers and...
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Tài liệu Báo cáo khoa học: 1,5-Diamino-2-pentyne is both a substrate and inactivator of plant copper amine oxidases ppt
... described above and only the ultrafiltrate mixed with Kovacs’ reagent Three model compounds (DDD, pyrrole and NADH) were used to compare spectral properties of their DMAB-adducts with that of the DAPY ... visible with m/z 211.3 (MS/MS: fragment peaks with m/z 193.3, 106.0 and 96.0), which probably reflects an adduct of the reaction product with ACA ESI-IT-MS of the low molecular mass fraction of the ... equipped with a 10 kDa cut-off filter The filtrate was used for spectrofluorimetry Fluorescence emission spectra of the DAPY oxidation product and model compounds (DDD, 3-hydroxypyridine, NADH and pyrrole)...
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Báo cáo khoa học: Downregulation of protease-activated receptor-1 in human lung fibroblasts is specifically mediated by the prostaglandin E2 receptor EP2 through cAMP elevation and protein kinase A pot
... action of PGE2 and ligands of receptor A2B and b2-AR (NECA and ISO) might result from different effects of those compounds on PAR-1 mRNA stability However, PGE2 did not influence the rate of PAR-1 ... levels of AP-2 and PAR-1 was shown [19] We tested the involvement of Sp1 and AP-2 transcription factors in PAR-1 expression and the possible influence of PGE2 on their activity For the analysis of ... involvement of the PKA pathway and the lack of a role of Epac in PGE2mediated inhibition of collagen synthesis in lung fibroblasts were documented [16] Suppression of fibroblast chemotaxis and TGF-b1-induced...
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Báo cáo y học: "HIV-1 Capsid Assembly Inhibitor (CAI) Peptide: Structural Preferences and Delivery into Human Embryonic Lung Cells and Lymphocyte" pptx
... the N-terminus of p55 is myristoylated triggering its association to the cytoplasmic side of cell membranes [7] and the release of the budding of viral particles from the surface of infected cells ... compositions of the CAI-BioShuttle and mass spectra of the investigated conjugates Top part of the figure: The inhibitor peptide, control peptides, and the transmembrane transport module are connected with ... antiretroviral interventions Material and Methods Chemical Synthesis and Purification of the CAI-BioShuttle For solid phase synthesis of the modules of CAI-BioShuttle and the control probes (figure...
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Báo cáo y học: "RNA interference against polo-like kinase-1 in advanced non-small cell lung cancers" doc
... proteins, and factors associated with malignant biological behaviors of cancer cells All of these genes are associated with the poor prognosis of cancer patients PLKs belong to the family of serine/threonine ... form two single-strands of RNA The strand that directs silencing is called the guide strand, and the other is called the passenger strand Ago2 protein selects the guide strand and cleaves its RNA ... form two single-strands of RNA The passenger strand rapidly degrades and the guide strand binds and cleaves the target mRNA, resulting in mRNA degradation Kawata et al Journal of Clinical Bioinformatics...
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Báo cáo y học: " Alpha-1-antitrypsin deficient man presenting with lung function decline associated with dust exposure: a case repor" docx
... plethysmography of 6.37 litres (94% of the predicted value), RV of 3.10 litres (126% of the predicted value), a RV:TLC ratio of 49%, and DLCO adjusted for alveolar volume of 2.8 (63% of the predicted ... epidemiological studies of A1AT-deficient people with or without work-related exposures The largest study of this question found a lower FEV value in adults ages 50 years and above with PiZZ phenotype ... pattern of exposure and response in our patient, together with the broader epidemiological evidence [1,2,11,12], is consistent with a relationship between the patient’s dust exposure and his COPD, with...
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báo cáo khoa học: " DNA ligase 1 deficient plants display severe growth defects and delayed repair of both DNA single and double strand breaks" potx
... repair kinetics of single and double strand DNA breaks induced in wild type and silenced lines Of the different forms of DNA damage, DSBs are one of the most cytotoxic and, if left unrepaired, ... and coomassie stained bands were electroeluted (BioRad) and used for immunisation In Western analysis of Arabidopsis cell extracts, antiserum to AtLIG1 (but not preimmune) identified a band of ... was used to analyse the repair of DNA double strand breaks in the wild type and silenced lines This analysis revealed similar levels of background (non-induced) DNA damage in all mutant and wild-type...
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Báo cáo y học: "Emulsified Isoflurane Preconditioning Reduces Lung Injury Induced By Hepatic Ischemia/Reperfusion in Rats"
... infiltration of neutrophilic leukocytes with perivascular edema formation and partial destruction of the pulmonary architecture and Grade dense infiltration of neutrophilic leukocyte associated with ... expected size of the amplified cDNA fragments of ICAM-1 and GAPDH was 326 and 452 bp, respectively Ten microliters of each RT-PCR were electrophoresed in a 1.5% agarose gel and stained with ethidium ... Care and Use of Laboratory Animals Surgical procedures of hepatic I/R A model of segmental (70%) hepatic ischemia was used as previously described14,15 Rats were anesthetized intraperitoneally with...
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DSLR 1.x crop factor vs. Full frame : Effect and reality
... (Dpreview) Có loại: Vertical, Horizontal & Diagonal angle view Và Picture angle of View lấy theo Diagonal angle of view, tức theo đường chéo sensor Như vậy, góc nhìn ảnh bị ảnh hưởng hai yếu tố: ... sensor khác nhau, với tiêu cự khác kể từ DSLR APS-C đời nảy sinh nhiều thắc mắc LỢI - HẠI APS-C , FF with wide angle lens Khi tìm kiếm sử dụng wide angle lens, tên nói lên mong đợi điều gì: Một ảnh ... với FF Sự kết hợp làm cho người tiêu dùng bị thiệt hại tiền đầu tư vào lens góc rộng APS-C, FF with tele lens Nói đến tele lens nói đến khả "kéo" hình ảnh lại gần người chụp Nói cách khác, tiêu...
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Tài liệu Module 1: Introduction to Microsoft Windows 2000 File, Print, and Web Servers pdf
... Professional Replaces Microsoft Windows 95, Microsoft Windows 98, and Microsoft Windows NT Workstation 4.0 in a business environment It is designed for businesses of all sizes Windows 2000 Professional ... benefits of Internet Information Services (IIS), Active Server Pages (ASP), and Microsoft Windows Media™ Services Benefits of Active Directory This topic describes the benefits of Active Directory and ... needs of reduced total cost of ownership (TCO), simplified and flexible administration, scalability, and standards-based protocols In addition, explain that Active Directory can be integrated with...
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Tài liệu Mechanical Ventilation for children with Lung Disease: ALI, ARDS, and Hypoxemic Respiratory Failure. docx
... of 10.2-10.6 ml/kg vs 7.2-7.3 ml/kg - Trials with benefit were closer to vs 12 - The mean tidal volume of the control group in both of these studies increased by 17-18% after randomization, with ... in dependent regions of lungs, with relative sparing of other areas radiographically, although may be substantial inflamation Diffuse alveolar damage, PMNS, macrophages and hyaline membranes, ... Lung Injury from Sepsis, with worse prognosis (? More likely MODS) •Recent estimates of mortality are between 30-40% for adults and 8-30% for children with ALI or ARDS Randolph 2009, 2003, Farias...
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Tài liệu Báo cáo khoa học: The endogenous retinoid metabolite S-4-oxo-9-cis-13,14-dihydro-retinoic acid activates retinoic acid receptor signalling both in vitro and in vivo pdf
... obtained a score of 0% For the analysis of limb buds, embryos were dissected out of the egg after and 24 h of incubation and rinsed in ice-cold NaCl ⁄ Pi The buds were cut off with small scissors ... certain combinations of retinoid receptor isoforms CV-1 cells were transfected with plasmids expressing a combination of either RARa and RXRb or RARb and RXRb, together with the reporter plasmid ... digestion of RARa and RARb In vitro-translated [35S]methionine-labelled RARa (A) and RARb (B) samples were pre-incubated with ethanol alone (A, lanes and 4; B, lanes and 4) or together with 100...
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Tài liệu Báo cáo khoa học: Mitogen-activated protein kinase phosphatase-1 modulated JNK activation is critical for apoptosis induced by inhibitor of epidermal growth factor receptor-tyrosine kinase pdf
... A B B C Fig Effect of AG1478 on phosphorylation of MKK4 and MKK7, and expression of MKP-1 and MKP-2 A, PC-9 cells were treated with 500 nM AG1478 for the indicated periods, and cellular lysates ... fetal calf serum and used for all of the experiments PC-9 cells were plated 24 h before transfection and co-transfected with 8.5 lg of pcDL-SRa 296JNK2(VPF) or pcMKP-1 and 1.5 lg of pBabePuro by ... cell type, cellular context and the nature and dose of treatment [22,23] Strong and sustained JNK activation is predominantly associated with induction or enhancement of apoptosis, whereas transient...
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Tài liệu Báo cáo khoa học: Analysis of oxidative events induced by expanded polyglutamine huntingtin exon 1 that are differentially restored by expression of heat shock proteins or treatment with an antioxidant ppt
... [39] and are associated with aggregates in the brains of HD transgenic mice [40] Hsp70 and Hdj-1 can inhibit polyQ aggregation and reduce the size of htt-polyQ inclusion bodies [15,36,37] and ... neuronal precursor cells and non-neuronal HeLa and COS-7 cells [15] Here, we have used COS-7 cells, which have the advantages of being transfected with a high level of efficiency and of displaying a flat ... the hypothesis that the expression of expanded httEx1 and the presence of httEx1 aggregates ⁄ inclusion bodies correlate with elevated ROS levels, and that NAC and Hsps have different abilities...
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Tài liệu Báo cáo khoa học: Role of transcription factor activator protein 1 (AP1) in epidermal growth factor-mediated protection against apoptosis induced by a DNA-damaging agent doc
... with EGF and ADR as described in (A), harvested at the indicated times after the addition of ADR, and used for immunoblot analysis of pro-caspase and caspase (C) Cells were treated with EGF and ... positions of the supershifted bands (C) Cells were treated with PD98059 and then with EGF for the indicated times Nuclear extracts were prepared from the cells and used for immunoblot analysis of c-Fos ... supplemented with 10% fetal bovine serum and used for all of the experiments Treatment of cells with ADR For most experiments, subconfluent cultures in 60- or 100-mm dishes were preincubated with or without...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn đặc tuyến hiệu suất h fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008