assess response to treatment monitor biological indicators
Báo cáo sinh học: "The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil" pdf
... the potential to execute necrosis in response to treatments with glycolytic inhibitors In contrast, the bioenergetic signature directly correlates with the apoptotic response to 5-FU treatment Overall, ... cells compared to controls (Figure 2), suggesting induction of apoptosis in response to 5-FU treatment Importantly, this induction of apoptosis following 5-FU treatment appears to be more pronounced ... ability to execute a ROS-mediated cell death response upon 5-FU treatment [11] On the other hand, small alkylating agents have been shown to be able to kill cancer cells resistant to apoptosis...
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báo cáo hóa học:" The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil" ppt
... the potential to execute necrosis in response to treatments with glycolytic inhibitors In contrast, the bioenergetic signature directly correlates with the apoptotic response to 5-FU treatment Overall, ... cells compared to controls (Figure 2), suggesting induction of apoptosis in response to 5-FU treatment Importantly, this induction of apoptosis following 5-FU treatment appears to be more pronounced ... ability to execute a ROS-mediated cell death response upon 5-FU treatment [11] On the other hand, small alkylating agents have been shown to be able to kill cancer cells resistant to apoptosis...
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EMERGENCY RESPONSE TO CHEMICAL AND BIOLOGICAL AGENTS - CHAPTER 1 ppsx
... facilities dearly want to get rid of what they now have to store since there is no permanent storage facility for high-level nuclear waste President Clinton promised to veto the senate bill saying ... Antidotes, Pretreatment, and Decon Basic Behavior of Chemical Agents To Decontaminate or Not To Decontaminate Types of Chemical Agents Chapter Biological Agents and Toxins Introduction Potential Biological ... Agencies and Response Teams Introduction U.S Marine Corps Chemical Biological Incident Response Force Department of Defense Chemical /Biological Rapid Response Team National Guard Rapid Assessment...
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EMERGENCY RESPONSE TO CHEMICAL AND BIOLOGICAL AGENTS - CHAPTER 2 ppt
... which is called a CAM (chemical agent monitor) which is used to monitor personal equipment and food from the effects of a chemical agent (Its capability extends to nerve agents, G-series and V-series, ... Unexplained odors: Smells may range from fruity to flowery to sharp/pungent to garlic/horseradish-like to bitter almonds/peach kernels to newmown hay It is important to note that the particular odor is completely ... atropine sulfate, equivalent to 0.36 mg of atropine MANAA is designed to be used by ambulatory nerve agent casualties with respiratory symptoms as a supplemental treatment after adequate injectable...
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EMERGENCY RESPONSE TO CHEMICAL AND BIOLOGICAL AGENTS - CHAPTER 3 doc
... monitoring, building installation monitoring, perimeter security, remote detector networks, or decon hot/warm zone monitoring Another detection instrument, the miniature chemical agent detector ... Selectable settings allow the APD 2000 to be used as a detector that automatically clears following an alarm or as a continuously-sampling monitor A fixed site remote detector featuring the APD 2000 system ... entry to the body: Inhalation, mosquito bite, or other exposure to virus-laden aerosols or droplets Person -to- person transmissible: Low Duration of illness: Days to weeks Potential ability to kill:...
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EMERGENCY RESPONSE TO CHEMICAL AND BIOLOGICAL AGENTS - CHAPTER 4 pdf
... biological weapon used By the time biological attack victims begin showing symptoms, it is often too late to save their lives However, many of the biological agents are not contagious personto-person ... (HVAPS), a biological sampler, a threshold ©2000 CRC Press LLC workstation, a liquid sampler, and a flow cytometer A biological detector as well as a Chemical Biological Mass Spectrometer (CBMS) biological ... and will tend to settle, finding its way into low spots such as trenches, depressions, or cellar holes Thus, monitoring procedures for propane are significantly different from monitoring procedures...
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EMERGENCY RESPONSE TO CHEMICAL AND BIOLOGICAL AGENTS - CHAPTER 5 potx
... to 3.1 miles PPID: The ToxiRAE Pocket Photo Ionization Detector continuously monitors hazardous and toxic gases or vapors in low part-per-million (ppm) concentrations The PPID provides fast response ... will start antidote i.v.s as opposed to a shot which takes a little longer to get into the system We want to get the antidote into the system, stop the symptoms that are occurring, and stabilize ... Marines at Camp Pendleton, CA and had just finished a deployment to Okinawa I came to Camp Lejeune, NC to join the Chemical Biological Incident Response Force and was promoted to Captain shortly...
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EMERGENCY RESPONSE TO CHEMICAL AND BIOLOGICAL AGENTS - CHAPTER 6 pot
... information on Toronto under the City of Toronto Act of 1837, but not on the new City of Toronto under the City of Toronto Act of 1997 (the new mega-city) Gaade states that prior to the reorganization, ... the entry/exit monitor The entry/exit monitor will work with the decontamination monitor to establish entry/exit points into the hot zone and decon area, monitor and document the movement of all ... charger, HP Deskwriter printer, Macintosh monitor, Weather-Pak receiver, Motorola Syntor transceiver, Macintosh computer hard drive, Bernouli Omega Multi-Disk, Macintosh keyboard, Windmeter, office...
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EMERGENCY RESPONSE TO CHEMICAL AND BIOLOGICAL AGENTS - CHAPTER 7 pot
... mentality tells us to go in and take care of the people We want to it quickly, and we want to be aggressive In Haz Mat response you really have to stop yourself to be safe You have to approach an ... funding, $271,000, to continue to put the team together The Southtowns team went on-line October 1, 1990 with full Level response capabilities “My paid job is as disaster coordinator for Erie County, ... were able to call the manufacturer to learn how hazardous it might be, how to approach it, how to clean it up and stop the leak We have both a cellular phone and a FAX machine in our response...
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EMERGENCY RESPONSE TO CHEMICAL AND BIOLOGICAL AGENTS - CHAPTER 8 ppsx
... streets to control the dust caused Times Beach to become a ghost town Dioxin is known to be a carcinogen The Firefighters Handbook of Hazardous Materials lists its toxicity for lungs and toxicity ... went into the storm sewer system and allowed for direct discharge into the harbor The other 50% went into the sanitary sewer system and to the sewer plant The amount recovered compared to the ... Canada-wide incident response, contingency planning, and Haz Mat and confined space training In Ontario, TEAM-1 has dispatch centers located in Hamilton, Burlington, Toronto, and London About...
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EMERGENCY RESPONSE TO CHEMICAL AND BIOLOGICAL AGENTS - CHAPTER 9 pot
... 65,000 to 68,000 pounds of equipment that includes approximately 2500 to 3000 different items from hand tools to generators to big wrecking tools,” relates Captain Hastings “The inventory list ... motion detectors, and all sorts of gadgets, but they take time to set up Everything has to be quiet to use the listening devices, and everybody has to be out of the area for the heat cameras to function ... tied to their arms A treatment leader is assigned to locate and set up the treatment area with regard to scene safety, ambulance access for loading, and location of the funnel point The treatment...
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EMERGENCY RESPONSE TO CHEMICAL AND BIOLOGICAL AGENTS - CHAPTER 10 docx
... days later Only of 48 sensitive monitors near the detonation site picked up low amounts of tabun Hand-held monitors detected no traces of the nerve agent, and monitors placed in homes five miles ... confidential for years, and even today information is still unavailable for 20 tons of the 114 tons of cargo Many survivors told police, doctors, and investigators that hours after the crash, ... chemicals that must be mixed together to form a deadly tool; weapons in storage contain only one of these chemicals) from storage space at the Umatilla Weapons Depot in Oregon to an ammunition plant...
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EMERGENCY RESPONSE TO CHEMICAL AND BIOLOGICAL AGENTS - CHAPTER 11 ppsx
... others from contamination, to communicate with other involved personnel, to transport patients to a medical facility, and to provide competent medical evaluation and treatment to exposed persons Selected ... management directors seeking to provide leadership and expertise in comprehensive emergency management, to serve as a vital information and assistance resource for state and territorial directors and ... of toxicology, personal protection and safety principles, assessment, decon, treatment, transport, planning, and more Volume II contains specific information for emergency department response to...
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EMERGENCY RESPONSE TO CHEMICAL AND BIOLOGICAL AGENTS - Appendix (END) doc
... without adverse effect Toxic: Relating to or caused by a toxin, able to cause injury by contact or systemic action The ability of a material to injure biological tissue; poisonous Toxicology: The study ... Association to provide guidance for chemical plant managers to assist them in cooperating with local communities to develop integrated hazardous materials response plans CAM: Chemical Agent Monitor used ... ability to store, transmit, and yield fresh water in usable quantities Area plan: A plan established for emergency response to a release or threatened release of a hazardous material Assessment: To...
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Báo cáo y học: "Regulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment" potx
... (IFN) response genes upon tumor necrosis factor (TNF) blockade and clinical response to treatment Figure Differential regulation of interferon (IFN) response genes upon tumor necrosis factor (TNF) ... clinical response to treatment as assessed by change in disease activity score (DAS) (DAS before treatment minus DAS 16 weeks after treatment) (a), European League Against Rheumatism (EULAR) response ... (months) EULAR EULAR Poor response to tumor necrosis factor blockade is accompanied by upregulation of interferon (IFN) response genes Figure Poor response to tumor necrosis factor blockade is accompanied...
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A study of bloating symptomatology, the role of gastrointestinal transit and the response to treatment with the 5 HT4 receptor agonist in patients with bloating predominant irritable bowel syndrome
... tract (Davidson et al, 1986) Serotonin is synthesized from tryptophan, which is first hydroxylated by tryptophan hydroxylase to form 5hydroxytryptophan.5-hydroxytryptophan is then decarboxylated ... 1978 Manning et al were the first to describe six key abdominal/intestinal symptoms, now referred to as 'Manning criteria', to help the diagnosis of IBS Those symptom criteria distinguish patients ... following symptoms: relieved with defecation associated with change in frequency of stools Associated with change in form of stools and two or more of the following symptoms: altered stool frequency...
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Leaching of arsenic in response to organic matter contamination in groundwater treatment practice
... Performance of the laboratory AIRU The removal efficiency of arsenic and iron in the developed AIRU at the laboratory was monitored in controlled condition where organic contamination was totally avoided ... The TOC removal efficiency was found to be less than 8% in the laboratory-scale AIRU (Table 3) Thus, two major phenomena would be related to the decrease in arsenic removal efficiency in response ... effluent waters of the laboratoryscale AIRU AIRU Influent Water HA (mg/L as TOC) SWW (mg/L as TOC) 15 15 30 30 AIRU Effluent Water HA (mg/L as TOC) SWW (mg/L as TOC) 13.7 13.9 28.1 28.5 HA: Humic...
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Individual Preparedness and Response to Chemical, Radiological, Nuclear, and Biological Terrorist Attacks - A Quick Guide potx
... disaster or a terrorist attack, it is tempting to act according to certain human instincts It seems perfectly natural to stop to help others or to try to contact family and friends But, especially ... least three stories below the roof to avoid the fallout deposited there You must stay inside this shelter for at least 24 to 48 hours to allow the radioactivity of the fallout to decline to safe levels ... into your shelter Finally, you can improve your protection against an undetected biological attack by implementing permanent measures to help keep biological agents out One way to this is to...
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báo cáo hóa học:" From HIV diagnosis to treatment: evaluation of a referral system to promote and monitor access to antiretroviral therapy in rural Tanzania" doc
... system could be used to promote access to an HIV treatment clinic among individuals diagnosed at VCT, and to monitor rates of referral uptake Similar mechanisms for monitoring referral rates ... access to HIV treatment, many expressed a desire for HIV treatment clinics to be in closer proximity to their homes: So I request services to begin at the [health] centres in each area It's easy to ... and HIV treatment clinic enabled us to monitor trends in the uptake of referral appointments and assess the effectiveness of the VCT service in linking diagnosed patients to available treatment...
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báo cáo hóa học:" Immunological response to highly active antiretroviral therapy following treatment for prevention of mother to child transmission of HIV-1: a study in Côte d’Ivoire" pdf
... death, or date of switch to a protease inhibitor (PI) to evaluate the response to non-nucleoside reverse transcriptase inhibitor (NNRTI)-based treatment Results From August 2003 to September 2005, ... Figure Immunological response in HIV-infected women A Immunological response in HIV-infected women exposed to nevirapine or acquired PMTCT resistance to nevirapine B Immunological response in HIV-infected ... from NNRTI-based to PI-based HAART during follow up Among the 19 women who switched to PI-based HAART, only four switches were related to treatment failure; the other 15 were done to manage NNRTIrelated...
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