as natural as status
Tài liệu Báo cáo khoa học: Multi-targeted activity of maslinic acid as an antimalarial natural compound pdf
Ngày tải lên :
14/02/2014, 14:20
... inhibition was observed on the aspartic protease pepsin However, a possible specific inhibition of plasmodial aspartic proteases could not be discarded, as strong inhibition by MA on the HIV protease, ... behave as a specific inhibitor of HIV protease, or the protease class A2 to which the HIV protease belongs, showing no activity on class A1 proteases (pepsin, cathepsin D) Remarkably, the only aspartic ... aspartic protease) and the aspartic protease inhibitor pepstatin A as controls The results (Table 2) showed that MA does not inhibit cathepsin D nor the aspartic protease activity in plasmodial protein...
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Tài liệu Báo cáo khoa học: Amino acid discrimination by arginyl-tRNA synthetases as revealed by an examination of natural specificity variants doc
Ngày tải lên :
18/02/2014, 13:20
... sulphate was converted to l-canaline by arginase treatment, essentially as described previously [61] The arginase required for this was obtained as a crude extract from the leaves of Canavalia brasiliensis ... nm was measured Preparation of L-canaline Synthesis of radioactive canavanine from l-canaline was based on a previously described procedure [60] using [14C]cyanamide as a guanylating reagent As ... amplicon was sequenced using the M13 primer to give the Canavalia ensiformis 3¢-terminal 55-base sequence The remaining 5¢ region was assembled taking into account conserved D-loop bases and the base-pairing...
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Báo cáo khoa học: Human telomeric G-quadruplex: The current status of telomeric G-quadruplexes as therapeutic targets in human cancer pdf
Ngày tải lên :
06/03/2014, 09:22
... reported G-quadruplexes as cancer drug targets subsequently [18,21,22], although relatively few have been evaluated in cell-based assays, or even with reliable in vitro telomerase assays [23,24] The ... singlestranded overhang, chiefly hPOT1, as well as possible uncapping of telomerase from the ends There are likely to be multiple mechanisms involved, some of which at least have cross-talk between them ... facilitates telomere length regulation by telomerase, and hPOT1 displacement disregulates telomerase function [7,8] Also, although the classic telomerase inhibition model does not appear to be followed...
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Báo cáo khoa học: "PARSING AS NATURAL DEDUCTION " pot
Ngày tải lên :
08/03/2014, 18:20
... leftmost resp the rightmost leaf., s has one daughter 276 • I f g is a basic category and has two daughter trees tt and t~_, then A is the list of all leaves of t s has two daughter proof trees Pt and ... exactly one syntax tree 275 On the basis of these augmented categories, the overall syntax tree can be built up together with the proof for a sequent As it has already been discussed above, a ... be partitioned into equivalence classes according to their corresponding syntax trees There is exactly one proof per equivalence class which can be identified as its normal proof This theorem...
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Báo cáo khoa học: "Natural Language Generation as Planning Under Uncertainty for Spoken Dialogue Systems" pptx
Ngày tải lên :
08/03/2014, 21:20
... utterance falls naturally into the class of statistical planning problems, rather than rule-based approaches such as (Moore et al., 2004; Walker et al., 2004), or supervised learning as explored ... Threshold-based approaches, in contrast, cannot (easily) reason with respect to the current content userQuit 20.0 20.0 60.0 6.4 Table 3: NLG bi-gram user simulation 6.2 We now formulate the problem as ... data-driven trade-offs as identified in the data analysis in Section 4: utterance length and number of provided attributes, as weighted by the regression model in Equation 1, as well as the next predicted...
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Báo cáo khoa học: "A PROLOG IMPLEMENTATION OF LEXICAL LANGUAGE FUNCTIONAL PROCESSING GRAMMAR SYSTEM AS A BASE FOR A NATURAL" pdf
Ngày tải lên :
24/03/2014, 05:21
... relationships in the same way as for intrasentential ones ~ is the second requirement: a s~antic representation has to represent the discourse as a whole and not as the mere union of the s~antic ... (9) John bought a car the engine has 160 horse powers In this case one has to take into account some ~nowledge of the world, nanely the fact that every car has exactly one engine To illustrate ... a translation procedure which is based on the association of formulas of intensional logic to the semantic forms appearing in the functional structure The reason not to take this approach will...
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Báo cáo khoa học: Natural polyphenols as proteasome modulators and their role as anti-cancer compounds doc
Ngày tải lên :
30/03/2014, 02:20
... trial phase Type of cancer Combined with Phase Phase Phase Phase Phase Metastatic colon cancer Pancreatic cancer Osteosarcoma Colorectal cancer Stage IV breast cancer Gemcitabine Gemcitabine Phase ... tea II I–II I I Phase I–II Phase I–II Phase II Phase Phase Phase Phase Tea polyphenols and theaflavins III III I–II II II II II II II Phase II Phase II Phase II FEBS Journal 275 (2008) 5512–5526 ... mitochondrial ATPase [101], calcium plasma membrane ATPase [102], protein kinase A [103], protein kinase C [104,105] and topoisomerase [106] The structure of the flavonoids determines whether they act as potent...
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Báo cáo khoa học: Natural-abundance isotope ratio mass spectrometry as a means of evaluating carbon redistribution during glucose–citrate cofermentation by Lactococcus lactis potx
Ngày tải lên :
30/03/2014, 15:20
... dehydrogenase (EC 1.1.1.1); 12, phosphate acetyl transferase (EC 2.3.1.8); 13, acetyl kinase (EC 2.7.2.1) results in diacetyl accumulation has received considerable interest [14,15] and, as has been ... d13Clactate Thus, as [citrate] increased, the d13Clactate steadily became more negative, reaching )16.2& at 34.8 mM (Fig 2A) In contrast, the influence of citrate was diminished as [glucose] increased, a ... Increasing the [citrate] 2.5fold, however, led to an % 3.5-fold increase in both acetoin and diacetyl This pathway has the potential to contribute to both the pyruvate homeostasis and the redox status...
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báo cáo hóa học:" The validity of self-rated health as a measure of health status among young military personnel: evidence from a cross-sectional survey" pot
Ngày tải lên :
20/06/2014, 15:20
... alcoholic beverage?" and was scored identically to the binge drinking item Weight status Weight status was assessed using BMI BMI is defined as the ratio of weight measured in kilograms divided ... health ratings: Smoking status Smoking status was assessed with the following item: What was your history of cigarette smoking (not including clove cigarettes) just prior to Basic Military Training? ... item as a measure of health status was assessed using health behaviors which are traditionally http://www.hqlo.com/content/4/1/57 important indicators of military fitness for duty such as smoking,...
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Báo cáo khoa học nông nghiệp " Nutrient recovery by rice crops as a treatment for aquaculture solid waste: crop yield, nutrient status and nutrient budgets " doc
Ngày tải lên :
21/06/2014, 04:20
... rice cv Thai Bonet was used for both wet and dry season crops All fishpond solid waste was applied before planting as was 50 % of the inorganic P and K The remaining P and K was applied at panicle ... dosages for wet season crops They normally used about 123 kg N/ha for wet season rice crops but only 113 kg N/ha for the dry season even though yield in the wet season was lower The reason behind this ... rivers by loading of fishpond waste, rich in nutrients (especially nitrogen, phosphorus and potassium) has emerged as a major concern Catfish culture in the Mekong Delta has been practiced for a long...
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Báo cáo lâm nghiệp: "Diagnosing plant water status as a tool for quantifying water stress on a regional basis in Mediterranean drylands" pdf
Ngày tải lên :
09/08/2014, 04:20
... H and D1 i.e between 89 and 92% In contrast, O oleaster plants growing in sites D2 and D3 had RWC’s as low as 70 to 72% A progressive decrease in RWC was recorded in Q coccifera plants from site ... Ψmin was calculated as the mean of Ψ L levels recorded during the warmest hours of the day (i.e between 10:00 and 14:00) and not as the minimum diurnal ΨL as measured at one point in the day as ... sclerophylls C siliqua, Q coccifera and O oleaster were dominant This site was considered as “healthy” (site H, figure 1b) and taken as a reference status of vegetation in comparison with the...
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báo cáo khoa học: "Thyroid-stimulating hormone elevation misdiagnosed as subclinical hypothyroidism following non-convulsive status epilepticus: a case report" ppt
Ngày tải lên :
10/08/2014, 23:20
... non-convulsive status epilepticus: a case report Journal of Medical Case Reports 2011 5:432 Consent Written informed consent was obtained from the patient for publication of this case report and ... Review of non-convulsive status epilepticus and an illustrative case history manifesting as delirium Australas J Ageing 2009, 28:110-115 Waterhouse EJ, DeLorenzo RJ: Status epilepticus in older ... speech was slightly confused, she was investigated at an internal medicine clinic and was found to have a TSH level of 5.7 μIU/mL and an fT4 level of 1.0 ng/dL At this time, our patient was diagnosed...
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Báo cáo y học: " Health status and lifestyle factors as predictors of depression in middle-aged and elderly Japanese adults: a seven-year follow-up of the Komo-Ise cohort study" doc
Ngày tải lên :
11/08/2014, 16:23
... items Three items addressed health: perceived health status, chronic diseases and BMI (25) Perceived health status was assessed by asking, “What is your current health condition: ... depression was also used in the Alameda County Study [19,21-23] Covariates Based on the items in the 1993 baseline survey, following three health status items and four lifestyle items were used as covariates ... variables were associated with a significantly increased risk for the development of depression although the odds ratio of smoking was almost same value as in Model Discussion Health status In this...
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Báo cáo khoa học: " Contributions to variability of clinical measures for use as indicators of udder health status in a clinical protocol" docx
Ngày tải lên :
12/08/2014, 18:21
... statistical analyses Each udder variable was analysed using Proc Mixed in the SAS Analysis System (Proc Mixed, SAS,1999) The following base-line model was applied: Outcomeijk = β0 + γ0k + µ0jk ... (random) variable is also assumed to be normal distributed with zero mean In case of binary response variables a logistic regression model was used In that case the residual term was binomially distributed ... with deep udders have an increased risk of mastitis [17] as these udders have an increased tendency to become soiled and hence populated by bacteria Therefore the reason for the observed falling...
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Báo cáo y học: "Socioeconomic status (SES) as a determinant of adherence to treatment in HIV infected patients: a systematic review of the literature" docx
Ngày tải lên :
13/08/2014, 06:20
... the association of such SES components, and adherence to antiretroviral treatment, where – and if – such an association was assessed Occupation was only assessed in terms of employment status, as ... income
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Báo cáo y học: " Status of complete proteome analysis by mass spectrometry: SILAC labeled yeast as a model system" ppt
Ngày tải lên :
14/08/2014, 16:21
... allowed as variable modifications Due to the high mass accuracy, the 99% significance threshold (p < 0.01) in the yeast database search was a Mascot score of 29 (Mascot peptide score is defined as ... identifying yeast proteins Number of peptides identifying yeast proteins (a) Unique peptides with score of at least 15 and mass accuracy at least 10 ppm Proteins are ordered by decreasing Mascot score ... a mass spectrum of yeast peptides eluting at a particular time point in the LC gradient As can be seen in the figure, mass resolution was very high (better than 50,000) and mass accuracy was...
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Simultaneous determination of sildenafil, vardenafil and tadalafil as forbidden components in natural dietary supplements for male sexual potency by high performance liquid chromatography–electrospray ionization
Ngày tải lên :
02/09/2015, 13:06
... elution was programmed as follows: A was maintained at 35% within the first 10 min, then linearly increased to 80% during the following min, then A maintained at 80% for another The column was washed ... detector The mass spectrometer used was a Micromass ZQ 2000 (Manchester, UK) equipped with an ESI probe and quadrupole analyzer The control of system and data acquiring was performanced with Masslynx3.5 ... initial mobile phase for the next injection The flow rate was kept at ml/min and the column temperature was maintained at 30 ◦ C Injection volume was l The detection wavelength was set at 292 nm...
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Investigation of phytoplankton as an overlooked marine source of natural endocrine disrupting chemicals
Ngày tải lên :
09/09/2015, 08:20
... Apparatus!used!for!LCIMS!Analysis! !30! 2.2.1.3! Apparatus!used!for!Bioassay!(Luciferase!activity)! .!31! 2.2.2! Human!CellIbased!Bioassays!(ERα,!ERβ!and!AR)!for!Measurement!of! Estrogen/Androgen!Receptor!Bioactivities!of!Phytoplankton!Extract! ... catenatum GC Gas chromatography GC–ECD Gas chromatography with electron capture detection GC–FID Gas chromatography with flame ionization detection GC–MS Gas chromatography coupled mass spectrometry ... analysis, such as metabolic stability, and to assess certain properties of drug molecules ! 15! 1.2.1.2 Total(Assays(of(Bioactivity(of(Seawaters(Samples( The chemical analysis has been seen as a major...
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