... to be related to the expression of granuphilin ⁄ slp4 in insulin-producing cells [28]. More- over, miR9 and other neuronal miRs including miR125b and miR128, are involved in the Alzheimer’ disease ... miRs are then incorporated into the RNA- induced silencing complex and bound to the 3Â-UTR of its target mRNA to induce either mRNA degrada- tion or translational inhibition [2,14,15]. Interestingly, unlike ... amplified using the primer pairs listed in Table 1, and then sequenced to determine the orientation of the fragments in the repor- ter vector. These constructs were then transfected into P19 cells...
Ngày tải lên: 18/02/2014, 17:20
... affecting the activity of ricin A chain (Eur. J. Biochem. 271 ) 1 57 involved the modification of arginyl residues 196, 213, 234 and 235 [9]. Of theses residues, only Arg213 is in the vicinity of the ... UK). R258 R213 R180 N78 D75 E 177 R134 Y123 Y80 N122 R258 R213 R180 N78 E 177 D75 R134 Y123 Y80 N122 R258 R213 R180 N78 D75 E 177 Y123 Y80 N122 R134 R258 R213 R180 N78 E 177 D75 Y123 Y80 R134 N122 A B Fig. 1. Models of hexanucleotide binding in the active site of ... crystal- lography. Protein Eng. 5, 77 5 77 9. 16. Chaddock, J.A. & Roberts, L.M. (1993) Mutagenesis and kinetic analysis of the active site Glu 177 of ricin A chain. Protein Engineering 6, 425–431. 17. Day,...
Ngày tải lên: 19/02/2014, 12:20
Trends in the European Investment Fund Industry in the Second Quarter of 2011 and Results for the First Half of 2011 potx
... 5,888 312 203 0 0 5, 570 11, 170 Turkey 20 74 - 179 -315 -106 -126 -188 -342 483 1,0 07 30 299 United Kingdom 1 ,76 7 1,599 1,536 690 888 2, 471 150 116 3,4 47 7 ,74 4 7, 7 87 12,620 Total 7, 659 12,535 9,656 16,421 23,128 43,028 -30,102 -39, 073 7, 8 07 14,644 18,149 47, 555 (1) ... 13.0% 75 2,055 2.4% 75 8,946 1.5% Italy 161,933 2 .7% 1 67, 668 -3.4% 175 ,358 -7. 7% Liechtenstein 26 ,71 3 0.5% 27, 071 -1.3% 26 ,78 4 -0.3% Luxembourg 1,8 57, 679 31.4% 1,869 ,79 1 -0.6% 1,880,612 -1.2% Netherlands ... billion invested in UCITS, this segment of the business accounted for just over 73 percent of the fund market at end June 2011, with the remaining 27 percent composed of non-UCITS. Table 7. ...
Ngày tải lên: 07/03/2014, 16:20
Trends in the European Investment Fund Industry in the Second Quarter of 2012 and Results for the First Half of 2012 pdf
... which the funds of funds data are included in the other fund categories; (3) net sales of non-UCITS are included in "other" funds, except net sales of special funds, which are shown in ... 4,342 -5 .7% 4,1 17 -0.6% Denmark 72 ,325 1.2% 70 ,4 27 2 .7% 65,856 9.8% Finland 51,440 0.9% 51,680 -0.5% 48,066 7. 0% France 1,1 07, 504 18.6% 1,132, 372 -2.2% 1,068,141 3 .7% Germany 230 ,79 2 3.9% 238 ,73 6 ... D D o o m m i i c c i i l l i i a a t t i i o o n n The combined assets of the investment fund market in Europe, i.e. the market for UCITS and non- UCITS, increased by 0.9 percent in the second quarter of 2012 to stand at EUR 8,4 37 billion,...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: H NMR study of the molecular structure and magnetic properties of the active site for the cyanomet complex of O2-avid hemoglobin from the trematode Paramphistomum epiclitum pdf
... stability of Pe Hb relative to other more autoxidizable globins. A reliable indicator of the dynamic stability of distal heme pockets in globins is the rate of reorientation of the aromatic rings in the ... E7 as the source of the H-bond to ligand on the basis of a partial sequence, which had indicated a Tyr on the distal E-helix. The similarity in the 1 HNMRspectraofthe three globin complexes in ... between the projection of the tilt of the z axis on the xÂ,y plane (dened direction of tilt of z and the x axis), and j % a + c denes the location of the rhombic (x, y) axes. The orientation of the...
Ngày tải lên: 23/03/2014, 17:22
“SCENOPHOBIA”, GEOGRAPHY AND THE AESTHETIC POLITICS OF LANDSCAPE “SCENOPHOBIA”, GEOGRAPHY AND THE AESTHETIC POLITICS OF LANDSCAPE doc
... best further the cause of an invigorated poli- tics of landscape? Reasserting the importance of landscape aesthetics A fine mess we’re in, Jackie A clearing in the bush The trees are all ... philosophy of aesthet- ics: is landscape quality inherent in the landscape or in the eye of the beholder?’, Landscape and Urban Planning 44 (4): 177 –198. LUND, K. (2005): ‘Seeing in motion and the touching ... disempowering effect on local inhabit- ants, at worst obliterating them from the history of the landscapes in which they live and from which they make their living. History provides many instances of...
Ngày tải lên: 30/03/2014, 16:20
Báo cáo khoa học: "The physiological status of Douglas fir seedlings and the field performance of freshly lifted and cold stored stock Conor." ppt
Ngày tải lên: 08/08/2014, 14:21
Báo cáo y học: "Tracking the genetic imprints of lost Jewish tribes among the gene pool of Kuki-Chin-Mizo population of India" pptx
Ngày tải lên: 14/08/2014, 14:21
Báo cáo y học: "Why are some children with early onset of asthma getting better over the years" -aneuploid-prostate-cancer-cells-after-tmz-tmz-bioshuttle-treatment.html#post143974
... Hospital, including PHC data of the statements made by the mid-wife in her records of the check-up of the mothers during the pregnancy ( 17) . In the follow-up at the age of seven, n= 191 children of ... suffering neonatal death and those living outside the region, were included in the study. At the age of seven, all of them still living in the region were included in a follow-up of their ... period, that their parents negated their ever having had asthma. Study limitations An implication of our findings regards the qual- ity of the information given to the parents when the Int. J....
Ngày tải lên: 26/10/2012, 09:48
THE 7 HABITS OF HIGHLY EFFECTIVE FAMILIES – 7 THÓI QUEN TẠO GIA ĐÌNH HẠNH PHÚC pdf
... 90% ã 3 7 Tụi bit mt bộ gỏi lỳc nào cũng thích chạy ra hiên trước nhà. Mẹ cô bé phải chạy theo, nhắc bé đi vào trong. Một lần cô bé ra ngoài hiên nhưng lúc đó bà mẹ đang bận nên không chạy theo ... Biểu đồ 7 Thói quen và các định nghĩa ở trang 5 07. Hãy kiên nhẫn. Làm từ từ. Hãy tôn trọng khả năng nhận thức của mỗi thành viên trong gia đình. Đừng áp dụng ồ t tt c nhng iu bn 3 4 ã 7 THểI QUEN ... chúng tôi thấy việc tuân theo những nguyên tắc này rất khó. Nhưng nếu không tuân theo thì còn khó hơn rất nhiều”. Gieo nhân nào, gặt quả ấy, những hành động không tuân theo nguyên tắc sẽ gây ra nhiều...
Ngày tải lên: 26/06/2014, 23:20
THE 7 HABITS OF HIGHLY EFFECTIVE PEOPLE - 7 THÓI QUEN ĐỂ THÀNH ĐẠT pdf
... hỳn vaõ hoồ seọ hửợ trỳồ baồn hùởt lông àïí àûa 7 Thối quen hôa nhêåp vâo cåc sưëng ca bẩn. 24 7 THỐI QUEN ÀÏÍ THÂNH ÀẨT 7 THOI QUEN ẽ THANH AT 37 Chuỏng tửi ùớ thựỗng beỏ tûå quët àõnh mổi hânh ... gia nâo trùn thùở giỳỏi baồn cuọng dùợ daõng nhờồn ra taỏc phờớm nưíi tiïëng 7 Thối quen àïí thânh àẩt (The 7 Habits of Highly Effective People) ca tấc giẫ Stephen R. Covey ln àûúåc mổi ngûúâi ... haồt cuóa cử gaỏi. Caỏc sinh viùn nhoỏm 2 nhao nhao phẫn àưëi: “Khưng phẫi, àố lâ cấi miïång ca bâ c”… Tuy nhiïn, cng cố mưåt vâi sinh viïn cưë gùỉng nhịn bûác tranh theo mưåt khung tham chiïëu...
Ngày tải lên: 26/06/2014, 23:20
Social media and the 7 steps of Buiding a new media strategy
... regard to providing value beyond the intrinsic value of the product. SOCIAL MEDIA AND THE 7 STEPS OF BUILDING A NEW MEDIA STRATEGY CAPABILITIES: DIGITAL AND SOCIAL MARKETING STRATEGY AND ... lead back to the center of your strategy – your website; the digital embodiment of your brand. OLD MARKETING MODEL Target the Audience and use interruptive techniques to convince. It was ... APPLE GOOGLE NORDSTROM’S STARBUCKS NIKE INNOVATION ACCESS TO INFORMATION CUSTOMER SERVICE GREAT COFFEE SPORTS PICK ONE. WHAT IS THE POINT OF THIS INITIATIVE IS IT AWARENESS? SALES? CUSTOMER LOYALTY?...
Ngày tải lên: 03/07/2014, 09:44
The chart below shows the sleep patterns of people in five different occupations according to a Canadian study
... wake at 6 a.m., but nap for two hours or so in the early afternoon. Thus the influence on one's sleep pattern is worthy of consideration when choosing an occupation. ...
Ngày tải lên: 04/10/2012, 10:02
The diagram below shows the average hours of unpaid work per week done by people in different categories
... households, but the number of hours women work in the home rises to 52 per week, much of it, on doubt, due to childcare responsibilities. Interestingly, when there are three or more children in the household, ... children enter the household, however, the inequality becomes even more pronounced. In families of 1 - 2 children, men maintain approximately the same number of hours of unpaid work as in childless ... actually represents a decrease. The data suggest that the increased presence of women in the paid work force has yet to lead to an increased role for men in the home. ...
Ngày tải lên: 04/10/2012, 10:02
The diagram below shows the typical stages of consumer goods manufacturing
... process, helps determine production planning. A product's design is not only the result of product research, but is also influenced by testing and market research. If the testing stage (after ... assembly and inspection) reveals unacceptable problems in the finished product, then adjustments will have to be made to the product's design. Similarly, market research, which examines the extent ... serves to foster future sales by devising suitable advertising for the goods. Thus the reality of consumer goods manufacturing goes well beyond a simple linear production process. ...
Ngày tải lên: 04/10/2012, 10:02