approach to the patient with lymphadenopathy and splenomegaly

... 052. Approach to the Patient with a Skin Disorder (Part 1) Harrison's Internal Medicine > Chapter 52. Approach to the Patient with a Skin Disorder APPROACH TO THE PATIENT WITH ... assume that the erosion is the primary lesion and the redness and scale are secondary, while the correct interpretation would be that the patient has a pruritic eczematous dermatitis with erosions ... Fig. 52-3) and to formulate a differential diagnosis (Table 52-4). For instance, the finding of scaling papules (present in patients with psoriasis or atopic dermatitis) places the patient in...

Ngày tải lên: 06/07/2014, 20:20

... elicits the desire to scratch. Pruritus is often the predominant symptom of inflammatory skin diseases (e.g., atopic dermatitis, allergic contact dermatitis); it is also commonly associated with ... Table 52-3 Common Dermatologic Terms A schematic representation of several common primary skin lesions (see Table 52-1). Chapter 052. Approach to the Patient with a Skin Disorder (Part ... epidermal atrophy). Scar: A change in the skin secondary to trauma or inflammation. Sites may be erythematous, hypopigmented, or hyperpigmented depending on their age or character. Sites on hair-bearing...

Ngày tải lên: 06/07/2014, 20:20

... MD; with permission.)[newpage] APPROACH TO THE PATIENT: SKIN DISORDER In examining the skin it is usually advisable to assess the patient before taking an extensive history. This way, the ... missing important individual skin lesions and make it possible to assess the distribution of the eruption accurately. The Chapter 052. Approach to the Patient with a Skin Disorder (Part 4) Figure ... correlates highly with diagnosis (Fig. 52-6). For example, a hospitalized patient with a generalized erythematous exanthem is more likely to have a drug eruption than is a patient with a similar...

Ngày tải lên: 06/07/2014, 20:20

... is characterized by small and large erythematous papules and plaques with overlying adherent silvery scale. Figure 52-8 Chapter 052. Approach to the Patient with a Skin Disorder (Part...

Ngày tải lên: 06/07/2014, 20:20

... lesions with a generalized arrangement are common and suggest a systemic etiology. Figure 52-9 Erythema multiforme. This eruption is characterized by multiple erythematous plaques with ... represents a hypersensitivity reaction to drugs (e.g., sulfonylamides) or infections (e.g., HSV). (Courtesy of the Yale Resident's Slide Collection; with permission.) Figure 52-10 ...

Ngày tải lên: 06/07/2014, 20:20

... against the surface of the skin and rotated with downward pressure until it penetrates to the subcutaneous tissue. The circular biopsy is then lifted with forceps, and the bottom is cut with iris ... of systems 9. Family history (particularly relevant for patients with melanoma, atopy, psoriasis, or acne) 10. Social, sexual, or travel history as relevant to the patient DIAGNOSTIC TECHNIQUES ... gently with a no. 15 scalpel blade, and the removed scale is collected on a glass microscope slide then treated with 1 to 2 drops of a solution of 10–20% KOH. KOH dissolves keratin and allows...

Ngày tải lên: 06/07/2014, 20:20

Ngày tải lên: 06/07/2014, 20:20

Ngày tải lên: 07/07/2014, 01:20

Ngày tải lên: 07/07/2014, 01:20

Ngày tải lên: 07/07/2014, 01:20

Ngày tải lên: 07/07/2014, 01:20

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Ngày tải lên: 07/07/2014, 01:20

Ngày tải lên: 07/07/2014, 01:20

Ngày tải lên: 07/07/2014, 01:20

... in their published work and were not able to overcome the emerging division of labor between religious and theological studies, on the one hand, and the anthropology of religion, on the other ... E” The two approaches to the study of “religious experience,” which I will refer to as the sui generis model and the ascription model, are summa- rized in table 1.1. They differ over whether there ... which the religiousness of the experience is understood to be inherent (sui generis) in the experience itself and the other in which it is viewed as ascribed to it. I will opt for the latter approach...

Ngày tải lên: 11/06/2014, 12:43

... will then be possible to identify the appetite or attitude to that type of risk, together with the capacity of the organisation to withstand that risk. Finally, the organisation can determine the ... need to understand the risks being taken when seeking to achieve objectives and attain the desired level of reward. Organisations need to understand the overall level of risk embedded within their processes ... responses. The objective is to achieve maximum sustainable value from all the activities of the organisation. Risk management enhances the understanding of the potential upside and downside of the factors...

Ngày tải lên: 21/02/2014, 12:20

... of these cytochromes have been proposed to be ter- minal Fe(III) and Mn(IV) reductases, although their role in the reduction of other metals is less well understood. To obtain more insight into ... anaerobic growth on either of the electron acceptors U(VI) and Se(VI) is due to the decaheme cytochromes c not recognizing either of these electron acceptors, we probed the relative affinities via ... involved in the reduction of either Fe(III) or Mn(IV) in MR-1 is thought to be composed of cytochromes and a qui- none, located in both the cytoplasmic membrane (CymA and menaquinone) and the outer...

Ngày tải lên: 07/03/2014, 09:20

... substrate client protein [the latter probably as a complex with Hsc70 and Ydj1(Hsp40)]. ATP binding to the Hsp90 N-terminal domains in the Hsp90 dimer then causes these N-domains to associate [32]. ... change may also be the signal for Hsc70, Ydj1 and Sti(Hop) to be displaced from the complex and for other cochaperone proteins, including Sba1(p23), to bind so as to produce the later multiprotein complexes ... streaked onto plates containing GA and RD. This revealed the Dpdr5 mutant to be hypersensitive to both drugs and the Dsnq2 mutant to be slightly sensitive to RD (Fig. 4B). Pdr5p is a broad-specificity...

Ngày tải lên: 07/03/2014, 21:20