application in tissue engineering and

... for Tissue Engineering Applications 33 3.1 Introduction As explained in chapter 1, inadequate vascularization is a major bottleneck limiting widespread clinical applications of tissue engineering, ... artificial tissue and organ replacements This is the field of tissue engineering, which has been defined as "an interdisciplinary field that applies the principles of engineering and the life ... preventing the realization of this goal 1.1.2 Vascularization is a major obstacle in tissue engineering While the field of tissue engineering has come a long way since its original conception in...

Ngày tải lên: 09/09/2015, 11:11

... proline and hydroxyproline As a non-essential amino acid, proline is synthesized from arginine/ornithine via the urea cycle and glutamate (directly or indirectly from glutamine via glutaminase) ... Blocki A, Peng Y and Raghunath M Applying the principle of macromolecular crowding to enhance the extracellular matrix deposition and remodelling in vitro for tissue engineering and cell-based ... protein samples were pooled and resolved under non-reducing conditions using in- house 5% resolving/3% stacking polyacrylamide gels on a Mini-Protean as outlined in Raghunath et al [93] Protein standards...

Ngày tải lên: 10/09/2015, 15:52

... (Figure 1) They include structural matrix proteins (collagens, laminin, fibronectin, fibrin, etc.) and molecules modulating cell migration (integrins), cell-cell and cell-substrate interactions ... networks containing a cell-binding site for ligation of cell-surface integrin receptors and substrates for MMPs, proteases implicated in wound healing and tissue regeneration [51,52] and fabrication ... collagen fiber assembly and structure Types II and VI collagen bind matrix receptors (integrins) Type II collagen can also bind to anchorin CII, whereas fibronectin binds to integrins A large proteoglycan...

Ngày tải lên: 10/08/2014, 05:21

... proteins and new tissue formation Hence, the properties of the scaffolding materials are crucial in determining the success of many tissue engineering applications The general tissue engineering ... vascularised tissues that can integrate with the host native tissues 2.2 Biomaterials for Tissue Engineering Biomaterials is one important component in tissue engineering and regenerative medicine and ... matrix proteins and new tissue formation Therefore, the properties of such biomaterials are crucial in determining the success of many tissue engineering applications Tissue engineering scaffolds...

Ngày tải lên: 11/09/2015, 09:10

... R.; Marins, F A S.; Loures, C C A.; Silva, M B Multivariate modeling in quality control of viscosity in fuel: an application in oil industry Fuel Injection in Automotive Engineering Rijeka: InTech, ... distribution, and reproduction in any medium, provided the original work is properly cited 40 Multivariate Analysis in Management, Engineering and the Sciences Thus, considering that the man, inserted in ... Sourligas and Foteinopoulos (2006) have used the first six principal components of Principal Component Analysis (PCA) as input variables in nonlinear modeling of oil properties Pasquini and Bueno...

Ngày tải lên: 23/03/2014, 03:20

... rebels ghting 0.130 in iraq attacked rebels turkish goverment D VC rebels ghting turkish government in iraq traversal of , starting from and ending in Each path (and its associated string) has ... (Section 3) in a summarization application that aims at producing both informative and uent headlines Our headlines are generated in an abstractive, bottom-up manner, starting from words and phrases ... produce headlines that have restrictions in the number of words allowed (10, in our case) The interpolation weights (Equation 2) are trained using discriminative training (Och, 2003) using ROUGE...

Ngày tải lên: 23/03/2014, 18:20

... Frontiers in Tissue Engineering Pergamon, Oxford, UK, p 700 22 Nerem, R M and Sambanis, A (1995) Tissue engineering: from biology to biological substitutes Tissue Engineering 1, 3–13 23 Shors, E C and ... plates, and meniscus arrows (20) 1.2 Tissue- Engineering Scaffolds The main goal of tissue engineering is to produce new tissue where it is needed Therefore, knowledge of the structure and functional ... degrading core and a more slowly degrading shell From: Methods in Molecular Biology, vol 238: Biopolymer Methods in Tissue Engineering Edited by: A P Hollander and P V Hatton © Humana Press Inc.,...

Ngày tải lên: 10/04/2014, 11:11

... Engineering II Basics of Tissue Engineering and Tissue Applications Volume Editors: Lee, K., Kaplan, D Vol 103, 2007 Tissue Engineering I Scaffold Systems for Tissue Engineering Volume Editors: Lee, ... and is finding many diverse applications in the emerging areas of tissue engineering and biomimetics [12, 45] Further research and development efforts into CCA modeling of whole body systems and ... emergence of tissue engineering as a core discipline of modern biomedical engineering, and recognizes the growing synergies between the technological developments in biotechnology and biomedicine Along...

Ngày tải lên: 27/06/2014, 10:20

... of agility in software and system development Now the International Conference on Agile Processes in Software Engineering and eXtreme Programming, XP 2007, is in its eighth edition During these ... involved and the approach to making a Comparing Decision Making in Agile and Non-agile Software Organizations Table Agile Principle Present in Company Agile Principle Present in Company A Present in ... Science+Business Media springer.com © Springer-Verlag Berlin Heidelberg 2007 Printed in Germany Typesetting: Camera-ready by author, data conversion by Scientific Publishing Services, Chennai, India Printed...

Ngày tải lên: 02/07/2014, 20:21

... supporting gestures and changing seating arrangements Gesture support would allow users to trigger actions such as deleting artifacts, cutting and pasting, and selecting groups of objects Supporting ... Tabletop Gaming In: Proceedings Third International Workshop on Pervasive Gaming Applications (PerGames’06), in conjunction with 4th Intl Conference on Pervasive Computing, May 7th Dublin, Ireland, ... to using index cards and handwriting on a table CardMeeting [1] attempts to bridge the gap between browser-based systems and physical card-based planning It displays electronic index cards in a...

Ngày tải lên: 02/07/2014, 20:21

... and Oldham’s Job Characteristics Model (JCM) [5] in our interview data and explain why and how these factors are maintained in our case study We continue by presenting the SCRUM methodology and ... down into discrete parts and incidents were identified, conceptualized, and named in the process of open coding Open coding was conducted line by line to ensure thorough grounding and critical thinking ... Programming, presented in International Conference on Software Engineering (2002) Evans, E.: Domain-Driven Design: Tackling Complexity in the Heart of Software, Pearson Education, Indianapolis, IN...

Ngày tải lên: 02/07/2014, 20:21

... systems, claiming that they can aid developers in understanding design complexity, in detecting design flaws, and in predicting certain quality outcomes such as software defects, testing, and maintenance ... Refactoring, and Simple Design Planning Small Releases, Planning Game, Sustainable Pace, Lessons Learned, and Tracking Customer Testing, Planning Game, and Onsite Customer Pair Pair Programming, Continuous ... Continuous Integration, and Collective Code Ownership Team Continuous Integration, Testing, Coding Standards, Metaphor, and Lessons Learned the CK suite (WMC, LCOM, DIT, and NOC) and two from Martin’s...

Ngày tải lên: 02/07/2014, 20:21

... Quality and Maintainable Code? 109 H10: The Maintainability Trend (MTi) per iteration defined in equation (2) for maintainability metric Mi ∈ M is higher during later iterations (it shows a growing ... them –assuming that our proposed model (2) and the Maintainability Index are proper indicators for maintainability - we will conclude that for the project under scrutiny XP enhances maintainability ... A., Kok, G.: Refactoring Test Code In: Proceedings of the 2nd International Conference on eXtreme Programming and Agile Processes in Software Engineering (XP’01) (2001) A Non-invasive Method for...

Ngày tải lên: 02/07/2014, 20:21

... impossible things possible Then, most Requirements Engineering activities are exploratory, acquiring and discovering requirements and knowledge about the problem domain And the Requirements Engineering ... important insights about the use of agile methods in general and XP in particular Software engineering is a knowledge intensive process that includes human and social factors in all phases: eliciting ... usability engineering and interaction design process among ASD methods vary In Extreme Programming (XP) [4], customers are equated to users and their opinions are valued during planning and release...

Ngày tải lên: 02/07/2014, 20:21

... iteration planning, stand-up meetings, burn-down charts etc) Still getting familiar with this new way of thinking and running projects, it was hard going to our customers and convincing them Usually ... spending time going through the values and principles of the Agile Manifesto, the main focus in the beginning was on the techniques and practices of agile methods (iterations, iteration planning, ... overall list and posted on the project Web site Future State Engineering Future State Engineering involved weekly meetings with client representatives to discuss future requirements and write stories...

Ngày tải lên: 02/07/2014, 20:21

... covered during the iteration planning meeting Team leads and SCRUM Masters should look for any signs of reduced stand-ups, pair programming, release planning and iteration planning meetings and immediately ... Coordinators Finally Sprints are grouped into Releases A Release covers one year of work, and delivers official project deliverables At the beginning of each Sprint, a Sprint Planning Meeting ... Sprint and the Sprint Retrospective meeting is held after each Sprint to discuss the just concluded Sprint and to improve the process itself The Sprint Review and Sprint Retrospective Meetings...

Ngày tải lên: 02/07/2014, 20:21

... messaging application Tool for importing libraries and header files Instant messenger application Daemon for sharing files and printers 1159 8954 3997 11076 7816 4715 2690 1045 4678 In order to investigate ... Technology and Global External Research), Advisor (Design Process Engineering) , and Software Reuse Program Prime In 1994 he spent a year as a Visiting Scientist at the Software Engineering Institute ... Software and Services group in IBM Haifa Research Lab (HRL) Her research interests involve aspects in software engineering and information systems Yael has a significant experience with guiding agile...

Ngày tải lên: 02/07/2014, 20:21

... elaboration References Anderer U, Libera J: In vitro engineering of human autogenous cartilage J Bone Miner Res 2002, 17(8):1420-1429 Hutmacher DW: Scaffolds in tissue engineering bone and cartilage Biomaterials ... and biophysical principles in extracorporal bone tissue engineering Part I Int J Oral Maxillofac Surg 2004, 33(4):325-332 Meyer U, Joos U, Wiesmann HP: Biological and biophysical principles in ... of tissue explants in suspension The cultivated and fabricated tissues may be used for studying the primary mixing of cells, and the patterns of cell differentiation and growth within growing...

Ngày tải lên: 11/08/2014, 23:22

... Cartilage tissue engineering using hydrogels Cartilage tissue engineering using hydrogels enables the delivery of cells and bioactive agents, including growth factors, peptides and ligands Hydrogels ... with lacunae These findings indicate the importance and relevance of biomaterials in cartilage tissue engineering and regenerative medicine An ideal scaffold for engineering a cartilage implant ... and for cartilage tissue engineering Some of the biomaterials and their associated outcomes in ESC-based cartilage tissue engineering and regenerative medicine are summarized in Table Some of...

Ngày tải lên: 11/09/2015, 09:57

... failure Tissue engineering has been heralded as the new wave to revolutionize the healthcare-biotechnology industry It is a multidisciplinary field and involves the integration of engineering principles, ... Significance and importance of tissue engineering 12 2.3 Poly(ε-caprolactone) thin films and matrices 16 2.4 Current progress of poly(ε-caprolactone) in biomedical engineering 17 2.5 Introduction ... membrane tissue engineering in ophthalmology, dermatology and even vascular graft engineering, polymer films are seen as favourable matrices because less material is administered and hence will invoke...

Ngày tải lên: 14/09/2015, 08:36