antigen presentation and recognition

... SDS-PAGE analysis and proteasome activity assays, concentrate and store proteasomes according to Subheading 3.7 References Monaco, J J and Nandi, D (1995) Genetics of proteasomes and antigen processing ... vol 156: Antigen Processing and Presentation Protocols Edited by: J C Solheim © Humana Press Inc., Totowa, NJ 17 18 Antón, Bennink, and Yewdell Table Molecular Weights, and Concentrations and Solvents ... Goldberg, A L and Rock, K L (1992) Proteolysis, proteasomes and antigen processing Nature 357, 375-379 Nandi, D., Marusina, K., and Monaco, J J (1998) How endogenous proteins become peptides and reach...

Ngày tải lên: 10/04/2014, 22:14

... by macrophages and DCs for presentation to T cells specific for the arthritogenic epitope CII259–273 Electron microscopy and antigen presentation to CII259–273-specific T and presentation cell ... prevention of CII uptake by DCs and macrophages results in down-regulation of antigen presentation and inhibits activation of CII-specific T cells in in vitro antigen presentation assays Since T ... CII and resulted in profound blockade of antigen presentation to T cells The involvement of macropinocytosis in uptake of autoantigens, such as CII, by both DCs and macrophages for subsequent antigen...

Ngày tải lên: 09/08/2014, 08:22

... alleles in this and other auto­ immune diseases warrants reconsideration of the paradigm It may be that MHC disease associations are driven less by allele-specific antigen presentation and more by ... HLADQB1, HLA-DQA1 and HLA-DRB1 that are required to confer risk of MS [25], and investigation of alleles present at HLA-DQ have shed light on haplotypic associations of HLA-DRB1*13 and HLA-DRB1*04 ... haplotype sequence will probably provide an improved understanding of MS disease mechanisms This brings us back to the venerable concept of antigen presentation as an explanation for MHC class II disease...

Ngày tải lên: 11/08/2014, 12:20

Ngày tải lên: 13/04/2013, 11:10

... Protein Carbohydrate Antigen có tính sinh miễn dịch yếu Nucleic acid 4.2 Antigen nguồn gốc vi sinh vật -Antigen bề mặt tế bào: Antigen nhóm máu, antigen MHC -Antigen tự động (Autoantigen) có tác động ...  Antigen phụ thuộc tuyến ức Antigen đa giá, tạo trí nhớ miễn dịch tốt, tăng hiệu ứng hai (antigen nhóm máu, protein cấy ghép, antigen virus ) kích thích miễn dịch với lymphocyte T helper  Antigen ... nhiều epitop Tính đặc hiệu antigen dựa vào tính đặc hiệu epitop Antigen đơn giá (Monotonous antigen) -polysaccharide, có epitop đặc hiệu Antigen đa giá (Polytonous antigen) -polypeptide, có nhiều...

Ngày tải lên: 23/10/2013, 14:15

... over six years and to examine the characteristics, presentation, underlying risk factors, outcome of patients and to highlight the possible causes of delaying diagnosis Materials and methods Here ... patients, 20 (60.7%) were male, and 13 (39.3%) female The mean age of all patients was 63±17 years Clinical presentation The mean time lapse between onset of symptoms and presentation at the hospital ... delayed presentation The mortality rate of 67% might be indicative of an association between early presentation and mortality (15) This may well be a logical conclusion since patients with severe and...

Ngày tải lên: 15/02/2014, 12:20

... the zero, xN and 0.87xH frequencies, versus the sequence of the TTF-1 HD Measurements were done at 11.7 T and 286 K Blank slots are for residues 29 and 42 (prolines) and Glu17, Leu34 and Lys46, ... (9.84 ± 0.20 ns) and two for sgi (0.26 ± 0.03 ns and 0.55 ± 0.06 ns) (supplementary Doc S1 and Fig S2) Comparison of results from MF and RSDM The results for sm obtained by the MF and RSDM approaches ... in the bar graphs of Fig 3, and the corresponding numerical values are given in supplementary Table S4 Linear correlations between J(0) and J(xN) and between J(0) and J(0.87xH) for the ` TTF-1...

Ngày tải lên: 18/02/2014, 16:20

... diagram of the timing of the presentation of stimuli We define a sequence to be a randomly-ordered set of all the letters (and the space and backspace symbols) The letters are randomly ordered for each ... interface Behavioral and Brain Functions, 6(1):28 J.R Wolpaw, N Birbaumer, D.J McFarland, G Pfurtscheller, and T.M Vaughan 2002 Braincomputer interfaces for communication and control Clinical ... Matrix-P300-Speller used by Wadsworth and Graz groups (especially g.tec, Austria) opts for a spatially distributed presentation of possible symbols, highlighting them in different orders and combinations to elicit...

Ngày tải lên: 20/02/2014, 05:20

... [2], and the dinucleoside 5¢,5¢¢¢-P1,Pn-polyphosphates (NpnN¢s, where N and N¢ are 5¢-O-nucleosides and n represents the number of phosphate residues in the polyphosphate chain that links N and ... nature and location of the oxygen and methylene groups bridging the four phosphorus atoms (see Supplementary material) Results and Discussion Comments on the synthesis of p4A analogues Recognition ... n.d n.d and pCH2pppA appear to be the strongest inhibitors of both the human and plant enzymes The Ki values estimated for the human enzyme, 1.6 and 2.3 nm, respectively, were over 30- and 20-fold...

Ngày tải lên: 16/03/2014, 14:20

... anonymity and safe from physical action References Anderson, C., & Dill, K (2000) Video games and aggressive thoughts, feelings, and behaviour in the laboratory and life, Journal of Personality and ... construction and presentation of their identity and sexuality in online chat rooms, to compare these processes with the literature on offline identity and sexuality in adolescence, and to assess ... around identity presentation and sexual exploration Although the coding categories included a variety of adolescent developmental themes, only two categories––identity presentation and sexual exploration––are...

Ngày tải lên: 23/03/2014, 03:20

... trunk and then disappears between C1 and C2 (Fig 4.3) Then two persons, H2 and H3 , walk close to each other near the parked cars They shake hands (Fig 4.4) and disappear between C2 , C3 and around ... uncertainties and ambiguities Having a good knowledge base (KB) and an effective reasoning scheme helps to improve event recognition performance Technically, we address uncertainty in observations and representational ... classes of uncertainty: logical ambiguity and detection uncertainty Their sources and ways to represent them are described below Event Modeling and Recognition using Markov Logic Networks Incomplete...

Ngày tải lên: 23/03/2014, 13:20

... [22] and enhances CTL epitope presentation and CTL-mediated lysis of KCs [6], we also wished to investigate whether E7 interfered with IFN-c-induced enhancement of antigen processing and presentation ... assessed the transcription of three MHC class I antigen processing and presentation- associated genes (pa-28, tap-1 and irf-1) in KCs and E7-KCs both before and after exposure of the cells to IFN-c, ... Transcription of genes associated with antigen processing and presentation in KCs and E7-KCs after IFN-c treatment mRNA was extracted from KCs and E7-KCs KCs and E7-KCs were treated or not, as shown,...

Ngày tải lên: 29/03/2014, 00:20

... transcribed rDNA loci and histone genes [36] A previous model proposed roles for transcription and for a specialized transcription factory in homologous chromosome recognition and pairing [37,38] ... hand, typical DSB-independent pairing is found in Drosophila and C elegans In these organisms, initiation of pairing and synapsis of homologous chromosomes does not depend on DSB formation and ... mechanism for homologous recognition to occur [31,32] These proteins then attach to the nuclear envelope, where they interact with the SUN and KASH domain proteins, SUN-1 and ZYG-12 [33] It has...

Ngày tải lên: 29/03/2014, 08:20

... requirements on determination and presentation of income and expense on available-for-sale debt investments It also shows when foreign exchange gains and losses and interest income from debt ... How you determine and present gains and losses on available-for-sale equity instruments? The table below summarises the determination and presentation requirements for gains and losses on available-for-sale ... foreign exchange gains and losses and interest income separately from other fair value changes The selected presentation method, once it is adopted, is applied consistently and disclosed in the...

Ngày tải lên: 30/03/2014, 03:20

Ngày tải lên: 24/04/2014, 12:35

Ngày tải lên: 24/04/2014, 13:16

... Pattern Video Sequence recognized YES Face Tracking NO Detection "Best Face" over time Faces Face Recognition new face Background Pattern Background Adaptation ệ ẵẵ è ệ ẹ ầỉ ệ ì ểệ ỉ ỉ ểề ì ểệ ... ểệệ ìễểề ì ỉể ệ ểệ ềỉ ệỉ ề ệ ééí ệí ééí ặ éỉ Foreground Model Foreground Region Edge Detection and Skeletonization Initial Ellipse Centroid Estimation Error NO Computation Ellipse Convergence...

Ngày tải lên: 24/04/2014, 14:09

... Bienenstock, Geman, and Potter (1997) and Geman, Potter, and Chi (1998), and by people studying generative models, such as Mumford (1994), Revow, Williams, and Hinton (1996), and Zhu and Mumford (1997) ... 1.4 Object Recognition 1.5 Scene Analysis: Merging Detection and Recognition 1.6 Low-Level Image Analysis and Bottom-up Segmentation Neural Network Architectures 10 12 Detection and Recognition: ... of thousands of classes This implies not only detection and recognition algorithms, but methods for sequentially learning new objects and incorporating them into the current recognition and detection...

Ngày tải lên: 31/05/2014, 23:23

... require debridement and toileting Clinical presentation however is similar in all the above conditions and includes suprapubic pain sometimes radiating to the groins Rectus and adductor spasm ... for the bending noted while standing or walking Osteitis pubis is self remitting and the symptoms are slightly lighter and decrease with time Bone scintigraphy and MRI are more sensitive than ... infectious form, osteomyelitis pubis, and tubercular osteomyelitis, and differentiate them by means of aspiration and histological evaluation Only then can a rational and specific therapy be initiated...

Ngày tải lên: 20/06/2014, 04:20

... require debridement and toileting Clinical presentation however is similar in all the above conditions and includes suprapubic pain sometimes radiating to the groins Rectus and adductor spasm ... for the bending noted while standing or walking Osteitis pubis is self remitting and the symptoms are slightly lighter and decrease with time Bone scintigraphy and MRI are more sensitive than ... infectious form, osteomyelitis pubis, and tubercular osteomyelitis, and differentiate them by means of aspiration and histological evaluation Only then can a rational and specific therapy be initiated...

Ngày tải lên: 20/06/2014, 07:20