analysis of relationships between genes tissues or treatments

... distributions of VantageScores For example, a 620 FICO score is the 25th percentile of the FICO score distribution, so the lowest score category of VantageScores was made up of scores below the ... (142,493) Same score category (green) Score category off by (yellow) 19% (34,631) 99% (177,124) Score category off by or more (red) 1% (1,454) 100% (178,578) Same score category (green) Total ... score of 680 The score places the consumer at the 38th percentile of the FICO score distribution, meaning he or she has a better FICO score than 38% of consumers His or her relative score for...

Ngày tải lên: 22/03/2014, 20:20

... alteration of miR expression may contribute to the initiation and manintanance of tumors as Page of 23 their abnormal levels have important pathogenic consequences: miR overexpression in tumors usually ... contributes to oncogenesis by downregulating tumor suppressors For example, the mir-17-miR 92 cluster reduces the transcription factor E2F1 in lymphomas and miR -21 represses the tumor suppressor PTEN in ... differences in phenotypic and pathologic presentation of melanocytic neoplasms at different ages We performed an exploratory analysis of 666 miR on formalin-fixed paraffin-embedded (FFPE)-primary melanoma...

Ngày tải lên: 18/06/2014, 16:20

... School of Medicine, Hangzhou, China 3Department of Preventive Medicine, Jiaxing University School of Medicine, Jiaxing, China Key Laboratory of Medical Neurobiology of Chinese Ministry of Health, ... http://www.biomedcentral.com/1471-244X/11/121 Page of Classification of Diseases and the DSM systems, and the Schedule for Normal and Abnormal Personality, measuring 11 functioning styles of personality disorder: the Paranoid, ... hands apart if hands were 15 cm or more apart at end of 10 seconds; (3) Mosquito hallucination for any grimacing, movement, or acknowledgment of effect (feeling of mosquito); (4) Taste hallucination...

Ngày tải lên: 11/08/2014, 15:22

... two isoforms of carbonic anhydrase (CA); while CCL expressed with an EST redundancy of 0.93%, the two isoforms of CA expressed with a combined EST redundancy of 1.40% (Table 3) The genes of the ... important as the size of the ESTs of this category (Fig 7) was more than 10 fold the size of the unigenes (Fig 6) in the group Besides, the ESTs of the pro- Page 21 of 25 (page number not for ... Acknowledgements The authors thankfully acknowledge the laboratory facilities provided for the work by Dr B Ravindran, Director, Institute of Life Sciences, Bhubaneswar Financial support for the work was received...

Ngày tải lên: 12/08/2014, 03:20

... transcriptional control of lung morphogenesis is key for normal development from primordium to a fully differentiated, functioning organ [100,101] Human lung growth has historically been categorised into ... injury, and is also required for the normal development of several tissues Mice lacking the Edn1 gene die of respiratory failure at birth and show severe craniofacial abnormalities, as well as cardiovascular ... pseudoglandular stage of lung development We therefore hypothesized that genes influencing normal airways development, especially during the branching morphogenesis stage of human lung development,...

Ngày tải lên: 12/08/2014, 13:22

... normal versus abnormal conditions of brain energy metabolism Hence, we tried to incorporate as many of the pathways as possible into the model A previous attempt for stoichiometric modeling of ... redistribution of corresponding fluxes in both cell types is indicative of the relative activity of the interactions Potential of the reconstructed model in the analysis of neural diseases Many diseases of ... bounds of the corresponding reactions were set to the reported values given in Table The degrees of freedom of the reconstructed reaction network, S, show the difference between the number of independent...

Ngày tải lên: 13/08/2014, 16:21

... (the optimal cut-off was 3% for the classifier, 25% or a score of 0.0000015 for PSAM, and 20% or a score of 4.7 for PSWM) and calculating again the FPR and TPR for each method False positives ... we suggest for these two genes (and also for a couple of others) a number of alternative PPAR-responding regions more distant from the TSS or downstream of it For the UCP3 gene, for which no ... indication for a PPAR target gene In this way, 28 out of the 38 human genes (74%) would have been identified as PPAR targets Similarly, for 29 of these 38 genes (76%) the analysis of their murine ortholog...

Ngày tải lên: 14/08/2014, 08:20

... specific group of genes with similar expression patterns for more refined functional analysis For example, analysis of periodically expressed genes in budding yeast showed that genes that encode ... annotation of these genes with respect to diurnal expression will be important for the selection of candidate genes for behavioral mutants in model organisms and for human psychiatric disorders, especially ... of 2,927 genes were identified as diurnally regulated in the mouse prefrontal cortex, and 2,458 (84%) of them have not been reported before as circadian genes or sleep/wakefulness regulated genes...

Ngày tải lên: 14/08/2014, 08:20

... that was used for Nicotiana benthamiana transient expression analysis were obtained from Professor Elliot Meyerowitz’s laboratory, California Institute of Technology, Pasadena, California , USA ... compensation of these two classes of receptor genes is suggested by both absence of phenotype in single loss -of- functions mutant of Arabidopsis and also from the antisense suppression studies of tomato ... seeds were obtained from Dr Harry J Klee’s Laboratory, Department of Horticultural Sciences, University of Florida, Gainesville, USA Wild-type coriander (Coriandrum sativum L) seeds were purchased...

Ngày tải lên: 15/09/2015, 22:05

... processes on the drip loss formation 1.2 Source of candidate genes for water holding capacity of pork The gene expression analysis was performed to investigate the correlation between the quantitative ... functional candidate genes on the quality of pork……… 37 3.2.1 The analysis of UBXN1…………………………………………… 37 v 3.2.2 The analysis of TRIP12…………………………………………… 37 3.2.3 The analysis of UBE3B…………………………………………… ... Genetics affecting pork quality………………………………………… 1.2 Source of candidate genes for water holding capacity of pork………… 1.3 The functions of candidate genes involve the mechanism of ubiquitination/deubiquitination...

Ngày tải lên: 19/11/2015, 16:33

... nmol/L for of vitamin D insufficiency definition according to The Endocrine Society (ES) 2011 criteria is supported by the majority of experts and is based on studies of relationships between ... formula for calculation of IR The computerized HOMA or HOMA2 developed by Oxford University (UK) has a number of advantages compared with HOMA1: IR is more accurately calculated by computer software, ... pathological factors of GDM are islet beta cell dysfunction and IR Until present, all the oral hypoglycemic agents have been not approved for use in pregnant women Therefore, research on factors that...

Ngày tải lên: 11/05/2016, 08:56

... between the groups of lines of both genotypes within ± SE of the mean (U 24.00, P < 0.05) The analysis of intergroup differences in the number of active regions for the six groups formed according ... distinguishing between the effects of the structural and regulatory genes involved in the control of a particular gene-enzyme system According to many authors, the variability of regulatory genes may ... F was performed according to deviations outside ± standard errors (SE) from the mean value of the observed parameter In this way, three categories of lines were made for the number of active...

Ngày tải lên: 09/08/2014, 18:21

... distribution of MAT/MA2C scores to normalize the scores from different platforms The estimation of the null distribution of MAT/MA2C scores was described in [13,14] The sum of Z-score divided ... Integrative analysis of ChIP-chip data Probe behavior model estimate and probe standardization for individual tiling array platforms For the one-color Affymetrix platform, the MAT algorithm [13] ... MM-ChIP Workflow illustrated for (a) ChIP-chip (b) and ChIP-seq data MA2C, Model-based Analysis of 2-Color Arrays; MACS, Model-based Analysis of ChIP-Seq data; MAT, Model-based Analysis of Tiling-array...

Ngày tải lên: 09/08/2014, 22:23

... that the abundance of transcripts for all of these genes was significantly increased in response to the hormone treatments (data not shown), confirming the efficacy of our hormone treatments Our ... BnWRKY genes in response to different hormone treatments Expression analyses of BnWRKY genes in response to different hormone treatments Changes in BnWRKY transcript abundance as a result of hormone ... as transcription factors Expression analysis of BnWRKY genes in response to fungal pathogens-S sclerotiorum and A brassicae Because the divergence of paralogous genes is often after the sub-functionalization...

Ngày tải lên: 12/08/2014, 03:20

... 'Body-map' analysis to visualize expression profiles for groups of genes across all tissues and diseases To illustrate the power of GeneSapiens analysis in the study of gene expression profiles of human ... to allow browsing of expression profiles of these genes and associated information as well as generation of correlations/scatterplots between any pairs of genes across any tissues Abbreviations ... well as the option of analyzing the correlation of any two genes across the whole database or subsets of tissues or diseases Taken together, we believe that the GeneSapiens analysis system provides...

Ngày tải lên: 14/08/2014, 21:20

... the pathogenesis of brain damage due to various causes Our results of a positive correlation between levels of free radicals and MMP-9 at operation for carotid artery stenosis further support this ... found no correlation between MCP-1 and radical levels and a negative correlation between ICAM-1 and these levels The lack of a positive correlation between radicals and these markers of inflammation, ... concentration of OXANO in the blank sample was subtracted from that of the corresponding test sample Around ten per cent of the signal was diminished as a result of the inhibitors 2.2.5 Measurement of MCP-1,...

Ngày tải lên: 26/10/2012, 10:03

... Expression Analysis Software (version 3.2, Affymetrix) First, single array analysis was performed [11] to calculate for each gene a signal, which represents a relative measure of the abundance of the ... expression profile between group (ethanol-treated) and group (control) a hierarchical cluster analysis was performed [26-28] For a quantitative estimation of the change in gene expression between ... an effort to find gene regulatory networks associated with low concentration of ethanol, we analyzed the interaction between the ethanol-regulated genes studied using Pathway Architect software...

Ngày tải lên: 31/10/2012, 15:28

... dimension analysis of COP data is more sensitive than traditional measures and that it may provide a good screening tool or measure of disease progression The disadvantage of this type of fractal analysis ... significance of between group differences for the same condition An alpha level of 0.05 was used as the criterion for significance of effect Levene’s test for homogeneity was performed on all ... analysis of COP may be more informative than traditional measures used to describe COP traces Surrogate Analysis The use of surrogate data analysis is common place to test for the appropriateness of...

Ngày tải lên: 03/11/2012, 10:09

... agent or the object of the action expressed by the predicate verb (Gordon, E.M:85) Voice is a form or a set of forms of a verb in which either person or thing that does something is the subject of ... linguistically valid definition of voice According to the authors of the Encyclopedia of Language and Linguistics, the term voice, in a narrow sense, refers to morphological categories This characteristic ... Keep pace with, Make room for, Take advantage of, Lose sight of, Make use of, Take care of, Lose touch with, Pay attention to, Take note of, Put an end to, and Take notice of From the S - V - O -...

Ngày tải lên: 07/09/2013, 12:58

... meanings of each word In a shorter word, an idiom can be seen as a number of words which, when taken together, shows the different meaning from the meanings of each word 1.1.2 Points of view of Vietnamese ... Investigation Chapter Idioms 1.1 Definitions of idioms 1.1.1 Points of view of English authors on idioms 1.1.2 Points of view of English authors on idioms 1.2 History of studying idioms 1.2.1 In England ... are divided into full words and empty words Accordingly, full words show lexical meaning That is the realisation of concept or emotion When we hear or see the word bicycle, for example, our concept...

Ngày tải lên: 12/12/2013, 00:03