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Tài liệu Báo cáo khoa học: Characterization of promoter 3 of the human thromboxane A2 receptor gene A functional AP-1 and octamer motif are required for basal promoter activity docx
... activation of phospholipase (PLC) Cb isoforms [1,3] In humans, but not in nonprimates, TXA2 signals through two TP isoforms referred to as TPa and TPb that are encoded by a single TP gene located ... sequence contains positive regulatory element(s) required for basal Prm3 activity Bioinformatic analysis of Prm3, using the matinspectorTM program [26], for transcription factor elements between )154 ... humans, TXA2 signals through two receptor isoforms termed TPa and TPb Although the physiologic requirement for two TXA2 receptors in humans is unclear, alterations in TP expression are implicated...
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Báo cáo khoa học: Activator-binding domains of the SWI ⁄ SNF chromatin remodeling complex characterized in vitro are required for its recruitment to promoters in vivo pot
... Tup-Ssn6 corepressor complex are differentially important for the repression of different target genes in fission yeast [45,46] Swi1 and Snf5 are known to be required for the structural integrity ... for comparison of wildtype and mutant strains Primers used for quantification of transcripts and promoter regions were for the most part designed using primer3 software [54] Primer sequences are ... were used as the input sequence for primer design using PRIMER3 software The positions of primers used for detection in chromatin immunoprecipitation experiments are indicated by arrows (B) Amount...
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Báo cáo khoa học: Amino acids at the N- and C-termini of human glutamate carboxypeptidase II are required for enzymatic activity and proper folding pptx
... the N-terminus of the protein was also shown to be required for the activity and/or secretion of the GCPII carboxypeptidase As for the N-terminally modified variants, the absence of the intracellular ... the media were substantially lower for the variants truncated further at the N-terminus (as compared to the 44/750 variant), and the 150/750 construct was not secreted at all The specific activities ... fold are cycled via the calnexin-calreticulinglucosidase I and II system within the ER lumen, providing space and time for the unfolded/partially folded proteins to acquire the correct 3D conformation...
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Báo cáo khoa học: Saccharomyces cerevisiae Ybr004c and its human homologue are required for addition of the second mannose during glycosylphosphatidylinositol precursor assembly ppt
... mammalian Pig-M protein and its yeast ortholog Yjr013wp are required for addition of Man1 to GPI precursors [19], and the PIG-B ⁄ Gpi10 proteins for addition of Man3 [20–22] However, a candidate GPI-MT-II ... and metabolic labeling was performed with 20 lCi [14C]ethanolamine for 23 h at 25 °C For radiolabeling of double mutant strains, cells were grown in SGlyYE medium for days at 25 °C, then grown ... statistically significant homology to the above query sequences, suggesting that the yeast GPIMT-II has little resemblance to known mannosyltransferases at the primary sequence level We therefore...
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Báo cáo khoa học: The sulfur atoms of the substrate CoA and the catalytic cysteine are required for a productive mode of substrate binding in bacterial biosynthetic thiolase, a thioester-dependent enzyme doc
... are known to be functional substrates for thiolase, but kinetic constants have been reported only for AcAc-SPP [3]; for example, Km and kcat are 73 lm and 469 ⁄ s for AcAc-SPP, whereas they are ... binding tunnel and its SH group closes off the catalytic cavity, near the catalytically important residues Cys89, His348 and Cys378 The residues forming the walls of the tunnel include the side ... at least partially, related to the preferred nonproductive binding modes of these oxoesters Members of the thiolase superfamily, being structurally and mechanistically related [1], are of considerable...
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Báo cáo sinh học: " Transcription and translation of human F11R gene are required for an initial step of atherogenesis induced by inflammatory cytokines" doc
... manuscript, and critically important for intellectual content of this work AB: Has made significant contributions to the conception, design and supervision of all experiments, performed data analysis ... plates were incubated at 37°C for hr Paraformaldhyde (4%), pH 7.4, was added to each well and incubation continued at 23°C for 15 The addition of paraformaldehyde, before washings, did not affect ... Cary NC) PROC MIXED software was used Four outlying observations were excluded from analysis All of the fixed main effects and their interactions were statistically significant at the 0.001 level,...
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báo cáo khoa học: " Plastid chaperonin proteins Cpn60α and Cpn60β are required for plastid division in Arabidopsis thaliana" docx
... mutations in ptCpn60β partially affect greening while chloroplast division is defective even under these conditions ptCpn60α and ptCpn60β are required for proper FtsZ ring formation To confirm the ... molecular chaperone, the in vivo roles are poorly understood GroE is essential for the viability of E coli [35] and this is partly because GroE is required for cell wall synthesis In addition to the ... FtsZ ring formation is impaired in the respective chaperonin mutants even though FtsZ protein levels are normal (Figure 4A) These results suggest that ptCpn60 proteins are not required for import...
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báo cáo khoa học: " Kinesin-5 motors are required for organization of spindle microtubules in Silvetia compressa zygotes" doc
... envelope breakdown (NEB) [14] when they are released into the cytoplasm and accumulate at the midzone and poles of the forming spindle They are required for maintenance of bipolar spindle integrity ... distance was significantly (p < 0.001, Student's t test) shorter in all drug treatments compared to controls, and all treatments were significantly different from each other (C) Multipolar spindles ... supernumerary spindle poles are formed at entry into mitosis, and the extra poles may be derived from cytasters Although the composition of fucoid cytasters is unknown, they are distinct small astral-like...
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Báo cáo y học: "Two discrete events, human T-cell leukemia virus type I Tax oncoprotein expression and a separate stress stimulus, are required for induction of apoptosis in T-cells" pptx
... HTLV-I infection required for ATL emergence suggests that most virally infected cells suffer apoptotic fates and that clonal escape from apoptosis to transformation is an exceedingly rare event Page ... transformed cell lines, as indicated, was after treatment with ZnCl2 or CdCl2 for 24 hours (B) or 48 hours (C) HTLV-I transformed cell lines treated with Zn showed lower cell viability compared ... manuscript and figure, and RK Yedavalli for assistance with reference formatting 21 References 10 11 12 13 14 15 16 17 18 Yoshida M: Multiple viral strategies of HTLV-1 for dysregulation of cell growth...
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Brutons tyrosine kinase and protein kinase c µ are required for TLR7 9 induced IKKα and IRF 1 activation and interferon β production in conventional dendritic cells
... Ethics statement All experiments and procedures were performed in compliance with Guidelines on the Care and Use of Animals for Scientific Purposes of the National Advisory Committee for Laboratory ... number of signaling molecules in various immune and cytokine receptor signaling [39] One of these molecules is Protein Kinase C (PKC) [40] Various PKC isoforms are known to be involved in the signaling ... centrifugation at 13,000 rpm for 10 mins at 4uC For immunoprecipitation studies, cell lysates were pre-cleared with Protein A/ G Plus-agarose in the presence of goat IgG (Santa Cruz) for h at 4uC mg of...
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Tips for Giving Effective PresentationsBelow are a few tips offered ppt
... or complex charts with small type Practice handling the overheads comfortably so you are not shuffling and dropping them as you speak For more details Slides are more formal, higher quality and ... and cover items that you don’t have time for in spoken remarks Overheads are informal visual aids for presentations to smaller groups (under 30) They offer an outline or highlights of your remarks ... your disk, software and equipment are compatible Don’t get carried away with animated gimmicks Charts and graphs can be rich with information and very effective if they are well designed Put them...
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AMINIMUM NUMBER OF PHYSICAL EDUCATION CREDITS SHOULD BE REQUIRED FOR GRADUATION OF COLLEGE
... students how to work independently to reach an aim; helps reinforce his self-confidence, self-reliance Team sports like football, basketball…helps develop social skills, when participating in them, ... rewards are distributed equally on the basis of mutual interactive behavior among individuals By this definition we learn that a cooperatives situation requires at least one competitor to fail for ... each competitor that wins Thanks to it, we can learn to share, to be self sacrificed,to work together with others for common goal These are the reasons why I feel physical courses should be part...
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Tài liệu A SAFETY GUIDE FOR SMALL OFFSHORE FISHING BOATS ppt
... sails are usually only a viable technology for use on vessels that have been specifically designed for sailing Smaller fishing vessels may require the addition of further ballast or an external ballast ... performance Diesel inboard engines There are few alternative technologies within the range of diesel engines that are suitable for installation in small fishing vessels Smaller diesel engines are ... impossible, especially in fatter vessels, with a fuller form The most critical areas of the stern for high curvature and steep angles are the zone just below the counter and the area just forward of...
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Tài liệu In this lab, 2 ISDN routers are required. If ISDN routers are not available, review the lab to become familiar with the process. An Adtran Atlas550 ISDN emulator is used to simulate the switch/ISDN cloud. pdf
... the reason for the call This information is shown for each channel: Tokyo#show dialer h Which dialer strings are associated with Dialer1? _ i What is the last status for dial string ... Specifying interesting traffic for DDR Traffic must be defined as ‘interesting’ to cause the DDR interface to dialup the remote router For the moment, declare that all IP traffic is interesting ... DDR dialer information Configure the correct dialer information so that the dialer profile and dialer interface function correctly This includes all of the following: • IP address information •...
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why colors are important for brands
... them with necessary spaces or animations to attract users Thus, all these are very simple tips to focus on and using them for small business can achieve unsurpassed growth rates It’s good to get ... matter a lot Connect: Aut hored by: Samir Feroze Samir Feroze is the founder of VeriQual Ltd, a software services company specialising in RoR, PHP, Android and iOS He has also founded Yello.PK which ... technology, Location based applications, financing early stage ventures and outsourcing In his spare time he likes to work on rotary See complet e prof ile Would you like to contribute to this...
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Tài liệu Chassis For Central Offices docx
... Interface Connector: D25F, adapters available Performance Alarms: Form C relay contacts normally open, normally closed and common are brought to connectors for each HDSL and management card Power Requirements ... www.adc.com From North America, Call Toll Free: 1-800-366-3891 • Outside of North America: +1-952-938-8080 Fax: +1-952-946-3292 For a complete listing of ADC's global sales office locations, please refer ... 85°C Humidity: up to 95% RH -noncondensing Regulatory CE marked (see CE Declaration for specific combinations allowed) Safety: EN60950 Emissions and Immunity: EN55022, EN-50081-1, EN-50082-1 (prior...
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Tài liệu Fiber Managment System Delivers Quick ROI for Central Office doc
... Situation For years at a large central office for an independent local exchange carrier, the number of fiber cables within the facility was limited so that installation and rearrangements ... system in place that reduced outages due to jumpers and required less time for jumper tracing, service restoration and installation of new jumpers required fewer labor hours Using straight work time, ... result, the time required for turning-up an optical circuit was reduced 30 minutes per circuit Data collected in the CO also showed a 50% reduction in the time required to install a jumper In...
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Tài liệu effective internet presenceted demopoulos’now required for success in business and life doc
... They are all online Who Are You? Who are you? Who, who, who, who? I really wanna know Who are you? Who, who, who, who? Tell me, who are you? – The Who, 1978 Today when people want to know “Who are ... networking sites allow you to join for free and then setup a “profile” – essentially information about yourself you want to share, and then “connect” with other people you know who are also using ... course these are just guidelines Some of them are open to debate Effective Internet Presence: Now required for success in business and life Ted Demopoulos Notice your personality is OK Actually it’s...
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Tài liệu . . . And Communications For All A Policy Agenda for a New Administration ppt
... be prepared for the transition to an all- broadband network; Jon M Peha of Carnegie Mellon offers a middle ground in spectrum management that balances between property claims and the call for a ... limited; therefore, it is imperative in the short term that expenditures are capped at sustainable and effective levels for the various USF-supported programs Specifically for the high-cost areas program, ... of error is ±2% for the entire sample For Internet users, n=2,822; margin of error is ±2% for this group For home broadband users, n=1,562; margin of error is ±3% for this group For home dial-up...
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