... NCI-H441, and human fetal lung explants H441 cells resemble bronchiolar epithelial Clara cells in phenotype and produce both SP-A and SP-B mRNA and protein [14] The hormonal regulation of SP-A and ... LY294002, rapamycin and PD98059 were reconstituted in dimethyl sulphoxide as mM, 50 mM, 50 µM and 10 mM stock solutions, respectively, and stored at -80°C in aliquots Insulin causes a timeand dose-dependent ... vehicle or insulin (2.5 µg/ml) for an additional 1, 4, and 24 hours The cells were then rinsed and trypsinized, and nuclei from control and treated cells were harvested The transcription elongation...
Ngày tải lên: 12/08/2014, 18:20
... cytokines and adhesion molecules can predict survival Indeed, and in contrast to BALF values, serum levels of IL-1 and adhesion molecules exhibited a high positive predictive value, sensitivity and ... serum and BALF levels of all studied molecules for ARDS development in patients at risk (groups B and C) are shown in Table The two groups of molecules studied (proinflammatory cytokines and adhesion ... (Table 5) Predictive serum and BALF levels of all studied molecules for surviving are shown in Tables and In contrast to BALF values, serum levels of IL-1 and adhesion molecules exhibited a high...
Ngày tải lên: 12/08/2014, 18:20
Báo cáo y học: " Expression of endothelia and lymphocyte adhesion molecules in bronchus-associated lymphoid tissue (BALT) in adult human lung" pot
... Semi-serial frozen sections of BALT were stained with mAbs against CD19 and CD3 (A), CD4 and CD8 (B), CD4 and CD45RO (C), and CD4 and CD45RA (D) L is in the airway lumen of the bronchus (A) B cell ... contributions NK and BHX contributed equally as co-first authors SAM and TM contributed equally as co-senior authors NK, BHX, SAM and TM designed the project, analyzed and interpreted the data, and wrote ... These results suggest that human BALT expresses endothelia and lymphocyte adhesion molecules that may be important in recruiting naive and memory/effector lymphocytes to BALT, where they may be...
Ngày tải lên: 12/08/2014, 14:20
Báo cáo khoa học: "Changes in some Blood Micronutrients, Leukocytes and Neutrophil Expression of Adhesion Molecules in Periparturient Dairy Cows" ppt
... taken for neutrophil immunostaining of CD18 and CD62L adhesion molecules, and for total and differential white blood cell counts Leukocyte counts Total and differential leukocyte counts were determined ... nutrients and leukocytes, and the proportions and MFI for the neutrophil adhesion molecules were done using the General Linear Model (SAS Institute Inc., Cary, NC, USA) The effects of cow and period ... commercial mineral and vitamin mix Samples of hay, concentrate and silage were frozen at –20ºC and analysed for contents of vitamins, minerals and trace elements The total daily requirements and allotments...
Ngày tải lên: 12/08/2014, 15:20
Báo cáo y học: "Human T-cell leukemia virus type I infects human lung epithelial cells and induces gene expression of cytokines, chemokines and cell adhesion molecules" ppt
... A549 and NCIH292 cells were harvested at 3, 5, and 14 days, followed by DNA and RNA extraction, as described below Samples of the culture supernatant were collected at and days after infection and ... production of cytokines and chemokines and induced the surface expression of cell adhesion molecule http://www.retrovirology.com/content/5/1/86 Activation of NF-κB and AP-1, and viral promoter LTR ... infiltrated lymphocytes (B and E) and macrophages (C and F) HTLV-I can be transmitted into lung epithelial cells from infected T cells and the integrated HTLV-I genes can be transcribed and expressed Lung...
Ngày tải lên: 13/08/2014, 05:21
Báo cáo khoa học: Functional classification of scaffold proteins and related molecules pptx
... scaffolds and adaptors are sometimes used interchangeably [1,4], the distinction between docking and adaptor is somewhat arbitrary [6], and docking proteins may also be termed adaptors and scaffolds ... as MyD88 scaffold and adaptor [3], linker for activated T cells (LAT) scaffold [3] and docking protein [6], GAB docking protein [6] and scaffold [4], mAKAP anchor protein [7] and scaffold [4], ... signaling components together and regulate their activity in complex and dynamic ways, involving activation and repression of activity Adaptor proteins are usually smaller and their function is simpler,...
Ngày tải lên: 06/03/2014, 22:21
Báo cáo Y học: Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules pptx
... from the a1 and a5 helices of both subunits Synthetic peptides corresponding to the respective sequences (93–107 and 167– 187) were found to strongly inhibit the 3¢-processing and strand-transfer ... bind substrate and exclude water Protein–protein interactions in the dimer include interactions between the catalytic triad residues (D25-G27), I50 and G51 at the tip of the flaps, and the antiparallel ... by the four termini in the dimer (residues 1–5 and 95–99) Additional interactions include a complex salt bridge between D29 and R87 of one subunit and R8 of the other subunit Thermodynamic analyses...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo khoa học: Upregulation of endothelial adhesion molecules by lysophosphatidylcholine pptx
... TAG AC-3¢ and antisense strand 5¢-CAG AAA ATC TCA GGA GCT GG-3¢; GPR4, sense strand 5¢-AGC ATT GCA GAC CTG CTG TA-3¢ and antisense strand 5¢-ATG GTA AGG CGC AAA GCA CA-3¢; G2A, sense strand 5¢-ACC ... standard protocol Primers were designed for AMs as follows: P-selectin, sense strand 5¢-CGA CGT GGA CCT ATA ACT AC-3¢ and antisense strand 5¢-CCA CAC TCT TGG ACG TAT TC-3¢; VCAM-1, sense strand ... of aortic adhesion molecules during aging J Gerontol Biol Sci Med Sci 61, 232–244 Zou Y, Jung KJ, Kim JW, Yu BP & Chung HY (2004) Alteration of soluble adhesion molecules during aging and their...
Ngày tải lên: 30/03/2014, 09:20
Báo cáo khoa học: Sugar and alcohol molecules provide a therapeutic strategy for the serpinopathies that cause dementia and cirrhosis pot
... neuroserpin in and 10% w ⁄ v Ficoll PM70, which have viscosities of 1.82 and 3.14 cP, respectively [49] In comparison and m glycerol have viscosities of 1.31 and 1.71 cP, respectively, and 0.6 and 0.8 ... mgÆmL)1) and the mixture incubated at 45 °C The rate of polymerization was assessed by densitometry of the monomeric band on 7.5% w ⁄ v nondenaturing PAGE The results are the mean and standard ... mutants of neuroserpin and a1-antitrypsin, possibly by binding to and stabilizing b-sheet A Results Glycerol, erythritol, trehalose and glucose reduce the rate of polymerization and increase the transition...
Ngày tải lên: 30/03/2014, 11:20
dynamical symmetries for nanostructures implicit symmetries in single-electron transport through real and artificial molecules
... spectrum and decays) Then we remain with a multiplet consisting of two singlets, (ground state S and exciton E2 ) and the spin triplet T , 20 HIDDEN AND DYNAMICAL SYMMETRIES OF ATOMS AND MOLECULES ... Single-Electron Transport Through Real and Artificial Molecules, DOI 10.1007/978-3-211-99724-6_2, © 2012 Springer-Verlag/Wien HIDDEN AND DYNAMICAL SYMMETRIES OF ATOMS AND MOLECULES representation l λμ ... rotator and hydrogen atom) and show how the dynamical symmetries DS emerge from the apparent symmetry SO(3) of the Schr¨ dinger equation o HIDDEN AND DYNAMICAL SYMMETRIES OF ATOMS AND MOLECULES...
Ngày tải lên: 29/05/2014, 23:50
Báo cáo hóa học: " Microstructure and adhesion characteristics of a silver nanopaste screen-printed on Si substrate" pdf
... Japan), and an optical microscope [OM] was used to observe the fracture surfaces of the screen-printed Ag nanopaste after the scratch test Results and discussion Figure 2a, b shows a TEM image and ... Science and Engineering, Sungkyunkwan University, 300 Cheoncheon-dong, Jangan-gu, Suwon, 440746, Republic of Korea Authors’ contributions KSK carried out the density measurement and scratch test and ... thermal analysis of the Ag nanopaste and participated in the screen printing SBJ participated in the design and coordination of this research All authors read and approved the final manuscript Competing...
Ngày tải lên: 20/06/2014, 23:20
báo cáo hóa học:" Microstructure and adhesion characteristics of a silver nanopaste screen-printed on Si substrate" docx
... Japan), and an optical microscope [OM] was used to observe the fracture surfaces of the screen-printed Ag nanopaste after the scratch test Results and discussion Figure 2a, b shows a TEM image and ... Science and Engineering, Sungkyunkwan University, 300 Cheoncheon-dong, Jangan-gu, Suwon, 440746, Republic of Korea Authors’ contributions KSK carried out the density measurement and scratch test and ... thermal analysis of the Ag nanopaste and participated in the screen printing SBJ participated in the design and coordination of this research All authors read and approved the final manuscript Competing...
Ngày tải lên: 21/06/2014, 17:20
báo cáo hóa học:" Microstructure and adhesion characteristics of a silver nanopaste screen-printed on Si substrate" doc
... Japan), and an optical microscope [OM] was used to observe the fracture surfaces of the screen-printed Ag nanopaste after the scratch test Results and discussion Figure 2a, b shows a TEM image and ... Science and Engineering, Sungkyunkwan University, 300 Cheoncheon-dong, Jangan-gu, Suwon, 440746, Republic of Korea Authors’ contributions KSK carried out the density measurement and scratch test and ... thermal analysis of the Ag nanopaste and participated in the screen printing SBJ participated in the design and coordination of this research All authors read and approved the final manuscript Competing...
Ngày tải lên: 21/06/2014, 17:20
Báo cáo hóa học: "Membrane Surface Nanostructures and Adhesion Property of T Lymphocytes Exploited by AFM" ppt
... of surface adhesion force, showing the fixed cells have a greater adhesion force than unfixed cells h Comparison of adhesion force of control groups and testing groups, indicating the adhesion force ... measured adhesion force of fixed and unfixed lymphocytes (Fig 3a, b) The results indicated that the fixative results in the increases of adhesion force of T cell membrane (Fig 3g) On the other hand, ... onefold; the adhesion force, however, decreased approximately to one-fifth control II As the activation time increased (6, 24, and 48 h), the adhesion force of lymphocytes decreased, and it was...
Ngày tải lên: 21/06/2014, 20:20
Báo cáo y học: " Adhesion molecules in different treatments of acute myocardial infarction" doc
... these adhesion molecules The objective of this prospective controlled, non-randomized study was to investigate the early course of six different adhesion molecules after myocardial infarction and ... of endothelial cells and an extravasation of leukocytes This consecutive extravasation is regulated by the sequential interaction of adhesion molecules and their cognate ligands, expressed by leukocytes, ... adhesion molecules ICAM-1 and Eselectin after acute myocardial infarction and following coronary angioplasty Int J Cardiol 1997, 61:113–118 Pudil R, Pidrman V, Krejsek J, Gregor J, Tichy M, Andrys...
Ngày tải lên: 12/08/2014, 18:21
Developing chemical proteomic tools connecting proteins and small molecules
... effectively expanding the chemical proteomics labelling’s application on both specificity and scope These include chemical (small molecules inhibitor) labelling (Chapter 2, and 4) and metabolites ... base pairs which make up DNA and to identify and map the approximately 20,000-25,000 genes of the human genome from both a physical and functional standpoint (Watson and Cook-Deegan, et al 1991) ... rate in aqueous environments and exhibit extreme selectivity and biocompatibility with chemical functionality in biomolecules (nucleic acids, proteins and metabolites) and have consequently been...
Ngày tải lên: 10/09/2015, 15:49
Theoretical studies of engertics, structures and chemical reactions on carbon and BN surfaces and related molecules
... Structures and Chemical Reactions on Carbon and BN Surfaces and Related Molecules Abstract This thesis focuses on the energetics, structure and reactivity of wide band gap materials such as diamond and ... carbon and borazine cyclacenes - 20 - YANG Shuo-Wang Ph.D Thesis 1.5 Motivations and Structure of this Thesis Diamond and c-BN are two of the most common wide band gap materials Oxygen and hydrogen ... functional theory and dynamic rockingbeam analysis", J Chem Phys 119 (2003) 4905 K P Loh, S.W Yang, J.M Soon, H Zhang, and P Wu, “Ab intio Studies of Borazine and Benzene Cyclacenes and Their Fluoro-substituted...
Ngày tải lên: 17/09/2015, 17:18
Assembly of nanoparticles and small molecules on graphene and their nonlinear optical limiting properties
... recrystallized using THF and water Yield: 79% 2.3 Results and Discussions First of all, we measured the UV-vis absorption and fluorescence spectra of these two pyrene ferrocene molecules with and without ... against absorbance for (a) PyFc1 and PyFc2 (left) and (b) GPyFc1 and GPyFc2 (right) …………………………………………………………………13 Figure 2.6 Possible ways of interactions between G and PyFc1………………………………………13 Figure ... attachment of molecules through π-π stacking and hydrophobic interactions while still preserving the intrinsic properties of graphene Recently, interaction of electron-donor and -acceptor molecules...
Ngày tải lên: 30/09/2015, 14:23
Contributions of Various Noncovalent Bonds to the Interaction between an Amide and S-Containing Molecules
... and angles in degrees 3536 www.chemphyschem.org 2012 Wiley-VCH Verlag GmbH & Co KGaA, Weinheim ChemPhysChem 2012, 13, 3535 3541 Interaction between an Amide and S-Containing Molecules b and ... of this entire problem, the global minithe literature is understandable as it occurs only in tandem mum of the complex between NMA and CH3SH is a product of with other, stronger noncovalent bonds, ... mol1, even though the H and S atoms are separated Each of the three S-containing molecules was paired with by 3.02 The last component with an E(2) above the 0.5 kcal NMA, and the potential energy...
Ngày tải lên: 16/12/2012, 15:21
Tài liệu Báo cáo khoa học: The effect of small molecules in modulating the chaperone activity of aB-crystallin against ordered and disordered protein aggregation pdf
... both aA- and aB-crystallin possess at least two binding modes, and that these are influenced by both external factors (e.g changes in temperature and pH) and intrinsic factors (e.g mutation and phosphorylation) ... formed by the ordered aggregation of RCMj-CN and a-synucleinA53T Electron micrographs of RCMj-CN (0.5 mgÆmL)1, A and B) and a-synculeinA53T (2.0 mgÆmL)1, C and D) 500 lgÆmL)1) following incubation ... formation of fibrils, which were long (between and nm), straight and unbranched (Fig 6C,D) Addition of Gly and Lys-HCl at 250 mm increased both the rate and magnitude of the change in ThT fluorescence...
Ngày tải lên: 18/02/2014, 16:20