adipose derived stem cells therapy through paracrine actions

... HE Stem cell therapy for neurologic disorders: therapeutic potential of adipose- derived stem cells Curr Drug Targets 2005, 6, 57-62 33 Satake K, Lou J, Lenke LG Migration of mesenchymal stem cells ... human adipose tissue -derived stromal cells after cerebral ischemia in rats Exp Neurol 2003, 183, 355-366 Kang SK, Shin MJ, Jung JS, Kim YG, Kim CH Autologous adipose tissue -derived stromal cells ... Kilroy G, Wu X, Gimble JM Immunophenotype of human adiposederived cells: temporal changes in stromal-associated and stem cell-associated markers Stem Cells 2006, 24, 376-385 26 Muir WW 3rd, Wiese...

Ngày tải lên: 07/08/2014, 23:22

... 2.2 Stem cells in tissue regeneration 2.2.1 Embryonic stem cells 2.2.2 Adult stem cells 2.2.3 Adipose derived stem cells Chapter Chapter v 2.2.4 Hepatic differentiation of adipose derived stem ... Injectable deliverey systems for stem cell therapy 20 2.4.1 Effect of mechanical cues on stem cells 21 2.4.2 Effect of biomolecular cues on stem cells 22 2.4.3 Hydrogels for stem cell therapy 23 2.4.4 ... of stemness marker genes on gelatin 49 microspheres 4.2.4 Adipogenic and osteogenic differentiation of 49 adipose derived stem cells 4.2.5 Hepatic differentiation of adipose derived stem 51 cells...

Ngày tải lên: 09/09/2015, 11:18

... 367(Suppl):S244-S253 Barry FP: Mesenchymal stem cell therapy in joint disease Novartis Found Symp 2003, 249:86-96 Zhang HN, Li L, Leng P, Wang YZ, Lv CY: Uninduced adipose- derived stem cells repair the defect of ... plausible possibilities The mechanism of regeneration could be through direct differentiation of stem cells that were introduced through the injection However, there is a possibility that the ... autologous mesenchymal stem cells Pain Physician 2008, 11:343-353 Lee JS, Lee JS, Roh HL, Kim CH, Jung JS, Suh KT: Alterations in the differentiation ability of mesenchymal stem cells in patients...

Ngày tải lên: 10/08/2014, 23:21

... mesenchymal stem cells of fetal or maternal origin from human placenta Stem Cells 22, 1338–1345 Bieback K, Kern S, Kluter H & Eichler H (2004) Critical parameters for the isolation of mesenchymal stem cells ... blood -derived mesenchymal stem cells into hepatocytelike cells Biochem Biophys Res Commun 330, 1153–1161 Seo MJ, Suh SY, Bae YC & Jung JS (2005) Differentiation of human adipose stromal cells ... mouse embryonic stem cells Hepatology 41, 836–846 Banas A, Teratani T, Yamamoto Y, Tokuhara M, Takeshita F, Quinn G, Okochi H & Ochiya T (2007) Adipose tissue -derived mesenchymal stem cells as a source...

Ngày tải lên: 30/03/2014, 04:20

... IPFPderived cells It was therefore interesting that they showed a pattern of expression on a high proportion of the IPFP -derived cells and of epitopes commonly abundant on adult stem cells derived ... was derived from haematopoetic, neural, or myogenic progenitors or stem cells Evidence for pericytes in the IPFP tissue and IPFPderived cells 3G5 distinctively stains pericytes and these cells ... marrow -derived mesenchymal stem cells, and we have determined a baseline for the use of FGF-2 in the culture of fat pad -derived cells Conclusion The present study showed that IPFP tissue contained cells...

Ngày tải lên: 09/08/2014, 10:23

... use of stem cells and precursor cells for this purpose The two types of stem cells that are being targeted for use in tissue regeneration are the Embryonic stem cells and the Adult stem cells ... precursor cells called Adipose tissue derived cells (ADSCs) (Zuk PA et al., 2001) These cells have variably been known as Processed Lipoaspirate (PLA), adipose tissue derived progenitor cells, adipose ... cardiac damage Presently there are two well defined types of stem cells – the embryonic stem cells and the adult stem cells The embryonic stem cells, which are found within inner cell mass of the embryonic...

Ngày tải lên: 08/11/2015, 17:01

... Currently, several candidates of stem cells, including embryonic stem cell, neuron stem cells, bone marrow -derived mesenchymal stem cell, and peripheral blood -derived stem cells have been frequently ... of adipose- derived mesenchymal stem cells (ADMSCs) for the treatment of stroke has seldom been discussed [19] Compared with embryonic stems cells and bone marrow -derived mesenchymal stem cells, ... transplanted cells into the host tissue [3] Interestingly, while stem cell therapy, including bone marrow -derived mesenchymal stem cells [15-17], embryonic stem cells [14] and endothelial progenitor cells...

Ngày tải lên: 18/06/2014, 16:20

... integration of the transplanted cells and the host tissue As compared with embryonic stems cells and bone marrow -derived mesenchymal stem cells, adiposederived mesenchymal stem cells (ADMSCs) have the ... J, Ratajczak MZ: Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis Stem Cells 2005, 23:879-894 Kee HJ, Sohn IS, ... through a 100 mm filter into a 50 mL conical tube to which mL of saline was added to rinse the remaining cells through the filter The flow -through was pipetted into a new 50 mL conical tube through...

Ngày tải lên: 18/06/2014, 16:20

... rat adipose- derived mesenchymal stem cells (ADMSCs) After culturing for 14 days, majority of isolated adipose- derived stem cells expressing CD29 and CD90 characteristic of mesenchymal stem cells ... experimental investigations [6,7,10-15] including bone marrow -derived mesenchymal stem cells (BMDMSCs), hematopoietic stem/ progenitor cells, and cells of embryonic origins, the ethical issue regarding ... through a 100 mm filter into a 50 mL conical tube to which mL of saline was added to rinse the remaining cells through the filter The flow -through was pipetted into a new 50 mL conical tube through...

Ngày tải lên: 18/06/2014, 19:20

... through a 100 μm filter into a 50 mL conical tube to which mL of saline was added to rinse the remaining cells through the filter The flow -through was pipetted into a new 50 mL conical tube through ... findings, therefore, suggest that ADMSC therapy significantly protected lung parenchyma from IR damage Figure Impact of Adipose- Derived Mesenchymal Stem Cells (ADMSC) Transplantation on the Severity ... endotoxin-induced systemic response by bone marrow -derived mesenchymal stem cells in mice Am J Physiol Lung Cell Mol Physiol 2007, 293:L131-141 23 Salgar S, Manning E, Ruiz P, Pham S: Mesenchymal Stem Cell...

Ngày tải lên: 18/06/2014, 22:20

... by sand rat adipose- derived mesenchymal extracellular 3D factor in the Immunohistochemical documentation ofstem cellsgrowthculture beta sand rat adipose- derived mesenchymal stem cells in 3D culture ... Increase in separate culture cells (AD-MSC) and annulus cells comderived mesenchymal stem cells (AD-MSC) and annulus cells compared with separate culture of AD-MSC and annulus cells alone Data from ... nucleus pulposus cells could secret soluble factors to direct stem cells towards the nucleus pulposus phenotype [41] Previous work on interactions of adult mesenchymal stem cells and disc cells by Le...

Ngày tải lên: 09/08/2014, 10:23

... marrow -derived MSCs Flow cytometric analyses of bone marrow -derived MSCs Cells were uniformly negative for CD34, CD45, and positive for CD44, and CD29 Figure Effect of simvastatin and bone marrow -derived ... which impair the stem cell functions to varying degrees, likely limiting the efficiency of stem cell therapy Therefore an approach to augment the angiogenic potency of bone marrow -derived MSCs transplantation ... density in ischemic limbs than cell therapy alone This may be partially due to the enhanced stem cells survival and greater differentiation rate of MSCs into vascular cells when administrated with...

Ngày tải lên: 10/08/2014, 05:21

... mesenchymal stem cells Stem Cells Dev 2005, 14:70-80 Aust L, Devlin B, Foster SJ, Halvorsen YD, Hicok K, du Laney T, Sen A, Willingmyre GD, Gimble JM: Yield of human adipose- derived adult stem cells ... cryopreserved human adipose- derived stem cells Cryobiology 2008, 57:18-24 Chen MY, Lie PC, Li ZL, Wei X: Endothelial differentiation of Wharton’s jelly -derived mesenchymal stem cells in comparison ... of stem cells derived from adipose tissue: implications for cell-based therapies Cell Tissue Res 2008, 332:415-426 Bunnell BA, Estes BT, Guilak F, Gimble JM: Differentiation of adipose stem cells...

Ngày tải lên: 10/08/2014, 10:20

... macrophages or NK cells activate T lymphocytes to proliferate Cytotoxic T cells are responsible for eliminating foreign cells or cells infected with viruses The proliferation of cytotoxic T cells can ... mechanisms of interactions between MSC and cells of the innate and adaptive immune systems Literature from multiple groups has shown sophisticated immunomodulatory effects of mesenchymal stem cells (MSC) ... AP1 activator protein-1 APP acute phase protein ASC adipose stem / stromal cells BFU-E erythroid burst-forming unit BMSC bone marrow stromal cells BSA bovine serum albumin CFSE carboxyfluorescein...

Ngày tải lên: 24/08/2014, 11:56

... gene therapy 21 1.3.5 Current status of gene therapy for glioma and breast cancer 22 1.4 Stem cells 1.4.1 Adult stem cells 1.4.1.1 Neural stem cells 1.4.2 Induced pluripotent stem cells 1.5 Stem ... suicide gene/prodrug systems in cancer gene therapy mediated by baculovirus-transduced neural stem cells derived from human pluripotent stem cells Poster presentation Stem Cell Society Singapore ... pluripotent stem cell derived- neural stem cell human induced pluripotent stem cell derived- neural stem cell expressing CodA human induced pluripotent stem cell derived- neural stem cell expressing...

Ngày tải lên: 09/09/2015, 18:56

... on gene expression of bone marrowderived mesenchymal stem cells and mononuclear cells Stem Cells 25, 1166–1177 Li L, Zhang S, Zhang Y, Yu B, Xu Y & Guan Z (2009) Paracrine action mediates the antifibrotic ... mesenchymal stem cells Science 284, 143–147 Porada CD, Zanjani ED & Almeida-Porad G (2006) Adult mesenchymal stem cells: a pluripotent population with multiple applications Curr Stem Cell Res ... Epstein SE (2004) Marrow -derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms Circ...

Ngày tải lên: 18/02/2014, 04:20

... astroglial cells and the bona fide adult neural stem cells) , type C cells (transit-amplifying cells derived from asymmetric division of Type B cells) , type A cells (immature neuroblasts derived ... orders@intechweb.org Neural Stem Cells and Therapy, Edited by Tao Sun p cm ISBN 978-953-307-958-5 Contents Preface IX Part Chapter Characterization of Neural Stem Cells Neural Stem Cells from Mammalian ... of stem cells in vitro (Bez et al., 2003) through direct cell-to-cell interaction Nevertheless, a single neurosphere contains only a small percentage of true stem cells, whereas the remaining cells...

Ngày tải lên: 30/03/2014, 23:20

... hES -derived vascular cells was performed through the left CCA We prepared four groups of the transplanted cells; Group1: PBS (50 ul), Group 2: hMNCs (3 × 106 cells) , Group 3: hESECs (1.5 × 106 cells) , ... Characterization of the transplanted vascular cells derived from human ES cells (HES-3) Characterization of the transplanted vascular cells derived from human ES cells (HES-3) A, Flow cytometric analysis ... suggest that vascular cells derived from human ES cells may have a potential to be a source for therapeutic vascular regeneration after stroke Abbreviations ES cells: Embryonic stem cells; VEGF-R2:...

Ngày tải lên: 18/06/2014, 15:20