... or between sex andabdominalobesity were observed in fully adjusted models When data analyses were further stratified by BMI andabdominalobesity status, abdominalobesity remained significantly ... (1.06-4.48) 2.03 (0.98-4.24) - abdominalobesity 52 1.49 (0.28-7.80) 1.31 (0.26-6.52) 1.19 (0.23-6.00) + abdominalobesity Obese - abdominalobesity + abdominalobesity 1,185 3.28 (1.91-5.65) ... TB, Penninx BW: Depressive symptoms and change inabdominalobesityin older persons Arch Gen Psychiatry 2008, 65:1386-1393 51 Bjorntorp P: Do stress reactions cause abdominalobesityand comorbidities?...
... study In conclusion, atherosclerosis begins in obese children and adolescents, and this tendency is intensified in the presence of MetS Obesity especially abdominal obesity, high TG level and insulin ... disease in obese population [17,18] In our study, the obese and MetS group both demonstrated increased fasting insulin than control group rather than fasting blood glucose Meanwhile, fasting insulin ... multiple stepwise linear regression analysis, suggesting a link between IMT, insulin resistance and dyslipidemia Insulin resistance is a common phenomenon and plays an important role in the cardio-cerebrovascular...
... promoting an increase in proopiomelanocortin and cocaine and amphetamine regulated transcript Taken together, these findings provide a compelling argument for the role for malonyl-CoA in regulating ... adipose tissue and gastrointestinal tract, as well as other sites, are known to reach the CNS to effect changes in feeding behavior and energy expenditure Thus, insulin, leptin and ghrelin, as well ... maintaining a lower food intake This is accompanied by a suppression in energy expenditure These data suggest that CPT1c can integrate carbohydrate and lipid nutrient sensing in the brain and...
... and drinking water ad libitum + Lot 5: Obese mice treated with metformin (500mg/kg) and drinking water ad libitum + Lot 6: Obese mice fed normal diet and drink water (no treatment) and drinking ... standard diet and drinking water ad libitum + Lot 2: Obese mice treated with ethanol fraction and drinking water ad libitum + Lot 3: Obese mice treated with chloroform fraction and drinking water ... flavonoids, tannin, catechin and alkaloid were found principally in ethanol, n-hexan and chloroform fractions Especially, there is no alkaloid in the ethylacetate fraction To determine relatively...
... Sciences and Technology 27 (2011) 125-133 Introduction Obesity can be considered as an abnormal state of lipid metabolism and increasing in developed and even developing countries The fact that the obesity ... significantly increases the risk of developing various livethreatening diseases, including type II diabetes, hypertension, coronary heart diseases stroke and certain cancers The worldwide prevalence of obesity ... flavonoids, tannin, catechin were found principally in the ethyl acetate and ethanol fractions In order to determine relatively the composition of natural compounds we used the technique of thin layer...
... molecules, including cyclins, cyclin-dependent kinases, their inhibitors and the retinoblastoma protein (RB), as well as E2Fs E2F and RB family members appear to participate in the regulation ... shown in Fig Excess calorie intake induces expression of RMI1 and E2Fs in adipocytes, and these changes in expression are expected to increase a positive interaction between the molecules The increased ... calorie intake due to hyperphagia and high-fat feeding induces expression of RMI1 and E2Fs in adipocytes, and causes a positive interaction between the molecules Increased expression of RMI1 and...
... long chain fatty acids (Elovl3), type iodothyronine deiondinase (Dio2), homeobox C9 (Hoxc9), insulin-like growth factor binding protein (Igfbp3), dermatopontin (Dpt), and b-actin are showed in Table ... standard deviation inflammatory response and IR development, were examined in mice As shown in Figure 3, PM 2.5 exposure induced a marked increase in macrophage (F4/80+ cells) infiltration in ... reduced in both eWAT and iBAT in response to PM2.5 exposure Recent studies have implicated PM2.5 in increased adipose inflammation and insulin resistance [11,12], and epidemiological studies indicate...
... established that abdominalobesity may result in insulin resistance and hyperinsulinemia [19,20] Epidemiological and population studies have established a direct correlation between obesityand the development ... leptin levels Insulin and leptin levels in the plasma of mice were determined spectrophotometrically by ELISA (Linco/Millipore, ApoE andobesity Billerica, MA, USA; cat no EZRMI-13K for insulin, ... glucose tolerance and insulin sensitivity To determine the role of ApoE in the development of obesity- associated insulin resistance and glucose intolerance, we performed the standard glucose tolerance...
... the glucose tolerance and insulin sensitivity of the ApoE) ⁄ ) · Ay ⁄ + mice, and triggered obesity, indicating that circulating ApoE is involved in increased adiposity and obesity- related metabolic ... phenotype and insulin and glucose levels became stronger with increasing body mass index [60,61] These findings again raise the interesting possibility that, although hyperplastic types of obesity ... suggesting that, in the absence of ApoE, decreased plasma lipid delivery to insulin sensitive tissues improves insulin sensitivity and prevents the development of diet induced obesity Using an...
... vitamin D status including plasma levels of 25(OH)D and vitamin D binding protein (DBP) and their relationship to systemic LL-37 levels in a group of critically ill patients including those with and ... Plasma 25-hydroxyvitamin D, Vitamin D Binding Protein, and LL-37 Concentrations in Critically Ill Subjects With and Without Sepsis and Healthy Subjects Vitamin D status differed in the critically ... Figure jects sepsis, vitamin ill subjects without critically subjects with Plasma criticallyD binding protein insepsis andillhealthy subPlasma vitamin D binding protein in critically ill subjects...
... obesityand links obesity to insulin resistance, impaired glucose tolerance and even diabetes Features of obesity- induced inflammation include increased production of proinflammatory cytokines, including ... number of inflammatory mediators including TNF-a Nicotine-activated STAT3 signaling induces the expression of TTP in macrophages and, in turn, TTP plays a key role in nicotine-induced anti-inflammatory ... important mediator of obesity- induced insulin resistance Interestingly, weight loss is associated with a reduction Nicotine ameliorates obesity- induced inflammation and insulin resistance The World...
... rehabilitative interventions in obese patients should include strengthening of the lumbar andabdominal muscles as well as mobility exercises for the thoracic spine and pelvis, in line with previous ... Pain Spine 2002, 27(17):1865-1874 Gilleard W, Smith T: Effect of obesity on posture and hip joint moments during a standing task, and trunk forward flexion motion International Journal of Obesity ... protocol to describe and quantify the functional mobility of the spine during flexion and lateral bending in order to investigate the relationship between obesityand LBP Materials and methods Thirty...
... in intracellular K+ and SIV Nef protein Alterations recombinant HIV- 1in T-lymphoblastoid cells incuAlterations in intracellular K+ in T-lymphoblastoid cells incubated with recombinant HIV-1 and ... cytostatic and cytotoxic against both CD4+ T cells and monocytoid cell lines [25] Several viral proteins, including influenza A virus M2, influenza B virus NB, HIV-1 Env, Vpu, and Vpr, induce alterations ... (A and C) and cells incubated with Nef protein (B and D) were examined by light (A and B) and fluorescent (C and D) microscopy that these cells have few endogenous membrane ion channels to interfere...
... obesityand links obesity to insulin resistance, impaired glucose tolerance and even diabetes Features of obesity- induced inflammation include increased production of proinflammatory cytokines, including ... number of inflammatory mediators including TNF-a Nicotine-activated STAT3 signaling induces the expression of TTP in macrophages and, in turn, TTP plays a key role in nicotine-induced anti-inflammatory ... important mediator of obesity- induced insulin resistance Interestingly, weight loss is associated with a reduction Nicotine ameliorates obesity- induced inflammation and insulin resistance The World...
... mellitus and depressed mood with obesityandabdominalobesity Total Characteristic n % 43 NonObesity obesity (BMI ≥ 30) (BMI < 30) (N = 290; (N = 693; 29.5%) 70.5%) n % n % No Abdominalabdominalobesity ... HRQL in the models with obesity, and 14% and 30% in those with abdominalobesity Those explained by significant interactions did not exceed one percent Also, cross-validating the complex interactions ... association between obesityand physical HRQL (similar to abdominal obesity) , not least because the etiological role of (abdominal) obesity for Figure Two-way interaction of obesityand diabetes on...
... shown good case-finding properties in primary care and hospital settings for anxiety and depression according to the Diagnostic and Statistical Manual of Mental Disorders and International Classification ... population) The finding that one point increase in the Δ PCS score was associated with an approximately 0.17 point decrease in the Δ HADS scores can be regarded as clinically significant, since the average ... be performed to confirm the findings in this study and investigate other possible mechanisms Competing interests The authors declare that they have no competing interests Authors' contributions...
... used in the geometrical projection in order to account for the scattering inside the phantom (Figure 3) Pinhole SPECT with scatter modeling To assess the ‘intrinsic’ CRC that can be reached by pinhole ... linear integration of the effective attenua∧ → tion coefficient μ y along the straight line from the → → point X to the scattering point → , and ρ x is the denx → sity at the point x (zero in ... reconstruction algorithm SW, MH, SP, and FJ participated in the data analysis andin the writing of the manuscript All authors read and approved the final manuscript Competing interests The authors declare...
... Conclusions In conclusion, in patients suffering from severe liver cirrhosis and ascites, portopulmonary shunt, intrapulmonary shunt and VA/Q inequality may induce a decrease in PaO2 and SaO2 in association ... manifested by dyspnea, platypnea and orthopnea and nowadays is more widely diagnosed occurring in chronic liver disease of all types and mainly in severe suffering patients [4, 9, 10, 11] Liver ... history, clinical examination, laboratory findings, and liver biopsy, which all patients underwent From a clinical point of view the patients’ conditions varied from moderate to severe according to...
... of the study and pariticipated in its design and coordination All authors read and approved the final manuscript Competing interests The authors declare that they have no competing interests Received: ... CGH is depicted by linear-ratios, and RT-PCR (y-axis) is delineated applying N-value A threshold level >1 (linear-ration and N-value) indicates significant DNA copy number gain Table Primers used ... USA) by random primer labeling, and μl Klenow fragments were added to the mixture DNA was incubated at 37°C overnight After labeling, unincorporated nucleotides were removed using MicroSpin G-50...
... from bound insulin intercede by increase in the insulin receptor Treatment with pyridoxine alone andin combination with insulin and Aegle marmelose to diabetic rats caused a reversal in the B ... receptors in the brain and the presence of insulindependent glucose transporters suggest that brain insulin participate in several cognitive functions, including learning and memory [41] In animal models ... control in diabetic rats treated with pyridoxine alone andin combination with insulin and Aegle marmelose leaf extract (Table-1) 5-HT and 5-HT2A receptor binding in the hippocampus of control and...