a novel tumor suppressor for gliomagenesis

... validated, guaranteed, and verified are used interchangeably to denote that state enclosures are mathematically and not only empirically proven to be correct Traditional validated techniques for ... engineering are analysis and design of robust, optimal, and adaptive controllers For nonlinear systems, robustness analysis with respect to uncertain initial states and parameters can be performed by calculating ... ESEARCH In this paper, VAL E NC IA-IVP has been introduced as a novel approach for validation of state enclosures for initial value problems with both uncertain initial conditions and tolerances...

Ngày tải lên: 12/01/2014, 22:04

... disSUT2fwd 5¢-TGACGCTCACCAAGCTATTGGTTT GTTTGGATCAATCGTCAGATATGAAGGCATAG GCCACTAGTGGATCTG-3¢ and disSUT2rev 5¢-TAT TAATATTCCTATATTTTACATAGGAGGAAATTA CATGCATGAAACCTACAGCTGAAGCTTCGTAC GC-3¢, respectively ... 5¢-TTCACGATTGAACAGGTAAACAAAATTTTCC CTTTTTAGAACGACATGCAGCTGAAGCTTCGTA CGC-3¢ and disRAS1rev CAAAACCATGTCATAT CAAGAGAGCAGGATCATTTTCAACAAATTATGC ATAGGCCACTAGGGATCTG-3¢ YEp351-SUT2 was constructed to contain SUT2 as ... 5¢-GACTGTCGATGATTATGGTTGCC CGCTGGCTTCCAAACCCTTATCGATACCGTCGA CCC-3¢ and SUT-GFPrev 5¢-AACAATTTCACACACA GGAAACAGCTATGACCATGATTACGCTATAGG GCGAATTGGGTA-3¢, respectively YEp351-SUT2 was linearized...

Ngày tải lên: 07/03/2014, 15:20

... AAACGCCTTCGCCCAAAGTTTAAAAGATGA TCATCTTTTAAACTTTGGGCGAAGGCGTTT TTTTCTCGAGAAAGATGCCGATTTGGGCGC GGGGCTCGAGGTTTTATATTTGTTGTAAAA ATATTATATATATATATAGGGTCGTATATA AAATTATAGAAAGCAGTAGA TAAAACAATG CTTCGAAGAATATACTAAAAAATGAGCAGG ... GCCCGTCGACATATTATATATATATATAGG CCCGCTCGAGTCTTAGAATTATTGAGAACG GCCCGGATCCTGATAGTAATAGAATCCAAA CCCCGAATTCAAATTATAGAAAGCAGTAGA AAGGCTCGAGAGATCTGTTTAGCTTGCCTC AAAAGTCGACGAGCTCGTTTTCGACACTGG TTTTGTCGACATGGCGCAACACGATGAAGC ... TTTTGTCGACATGGCGCAACACGATGAAGC CGTAGACAAC GGGGGGATCCTTACATAAGCGTACAACAAA CACTATTTGATTTCGGCGCCTGAGCATCA TTTAGCTTTTT ATCCAAAGTTTAGCCGATGACCCAAGCCAA TTGGCTTGGGTCATCGGCTAAACTTTGGAT AAACGCCTTCGCCCAAAGTTTAAAAGATGA...

Ngày tải lên: 16/03/2014, 01:20

... CAAATACaAgCGGGtGAACGGGGCTATCGTCTGTGaAAAAGGC GGAATTCGCgGCcGCCtTGTCACACTCACAAATCCGATTCTC GGGCAAGCTTGCgGCcGCAATCTGCTTTCGAcAGAATCTGAAcACATAttcgAAAAAGTATATGC GGGCAAGCTTGCgGCcGCAATCTGCTTCCGAcAGAATCTGAAcACATACAgCTATATATATAGG ... 2a+ 2b+ 2– 3+wt 3+YIRN 3– TAATACGACTCACTATAGGGAGACCACAACGGTTTCC GGGCaagcTTCCCCGTCTCCtCCAGGATCATCtTCCCG GGGCAAgcttgCTaTTcCCTCCTACTCCTcTTACGGATGCTACTGCGGCtgGGGGGG GACTGCAaCCCCAAAtCGGACAG CAAATACaAgCGGGtGAACGGGGCTATCGTCTGTGaAAAAGGC ... GGGCAAGCTTGCgGCcGCAATCTGCTTCCGAcAGAATCTGAAcACATACAgCTATATATATAGG GGAATTCTGCAGTTAGCATTTgagCTCtccCTTGCACAAgAAGTCCGG Ó FEBS 2003 3020 P Prijatelj et al (Eur J Biochem 270) Vista, CA), digested with BamHI/HindIII (fragment 1, 60...

Ngày tải lên: 17/03/2014, 03:20

... AGGAAAAAAATTTAAATCCACCATGGTGAGCAAGGGCGA GGAGCT AGGAAAAAAATCGATCGCGTTAAGATACATTGAGTTTGGA C PCR to check pAd5CMV-EGFP GGCACCAAAATCAACGGGAC AGGAAAAAAATCGATCGCGTTAAGATTACATTGAGTTTGGA C Amplification of TK from pMBP-TK AGGAAAAAAATTTAAATGCGCGTATGGCTTCGTAC ... GATAACAGATTTAAATCCTTCGAACAGAATCGAT GGCCATCGATTCTGTTCGAAGGATTTAAATCTGTT PCR to check pAd5CMV/TCS CGTGTCATATGGATACACGGG TCCAGCATGGCTACAACCTC EGFP amplification from pEGFPC3 AGGAAAAAAATTTAAATCCACCATGGTGAGCAAGGGCGA ... from pMBP-TK AGGAAAAAAATTTAAATGCGCGTATGGCTTCGTAC AGGAAAAAAATTTAAATGAGTTAGCCTCCCCCATC AGGAAAAAATTCGAATCAGTTAGCCTCCCCCATC plasmid was then used to replace the E3 region by the CMVp and TCS, in pTG3622,...

Ngày tải lên: 20/06/2014, 01:20

... http://www.virologyj.com/content/5/1/135 (A) A T A A T T T A A T C (B) G C C G G/GATCCAAGCGGTCATCCGTATAATATTACCGGATGGCCGC/GGCCGCAAAAGAGCT/C C G BamHI NotI SacI T A A T C G T G G C G C C G AAG CGCCTTTTCCT original viral sequence ... CATGATCAACTGCTCTGATTAC GGGCTTCCCGTACTTTGTG TGGATTTAGCTCCCTGAATG TYLCV primers for Q-PCR (176 bp amplicon) Ty 2164+ Ty 2339- CTAAGAGCCTCTGACTTACTGC AACATTCAGGGAGCTAAATCCAG 200 nM 200 nM Actin2 ... GGTCGCTTCGACATARTCACG 200 nM 200 nM Sequencing of TYLCV cloned sequences pGreen1589 (+) pG1825(-) 579 (+) 1141 (+) 1741(+) 2321(+) CACGACGTTGTAAAACGACG CACAGGAAACAGCTATGACC GATGTTACTCGTGGATCTGG CATGATCAACTGCTCTGATTAC...

Ngày tải lên: 20/06/2014, 01:20

... MasterScan: a database of shotgun mass spectra The MasterScan is a flat file database that stores all mass spectra acquired from all analyzed samples, including technical and biological replicates, ... available for testing local installations of the software LipidXplorer benchmarking: the dataset E coli total lipid extract was purchased from Avanti Polar Lipids (Alabaster, AL, USA) and analyzed ... demonstrated that LipidXplorer takes full advantage of the high mass resolution and mass accuracy of a hybrid tandem mass spectrometer It has also become apparent that averaging and alignment of related...

Ngày tải lên: 09/08/2014, 22:23

... Compared to the macaque models, the marmoset model of CIA shows several advantages First of all, common marmosets are smaller and reach their adult age earlier than macaques, which saves capacity ... type II collagen an experimental model of arthritis J Exp Med 1977, 146:857-868 Cathcart ES, Hayes KC, Gonnerman WA, Lazzari AA, Franzblau C: Experimental arthritis in a nonhuman primate I Induction ... preclinical studies Aside from the advantages of using marmosets, a main drawback of this model should be considered The evolutionary distance between marmosets and humans is significantly larger than...

Ngày tải lên: 12/08/2014, 15:22

... SC, Yamaoka S: Activation of NF-kappaB by HTLV-I and implications for cell transformation Oncogene 2005, 24:5952-5964 Grassmann R, Aboud M, Jeang KT: Molecular mechanisms of cellular transformation ... human interleukin-2 receptor alpha chain promoter: activation of a nonfunctional promoter by the transactivator gene of HTLV-I Cell 1987, 49:47-56 Maruyama M, Shibuya H, Harada H, Hatakeyama M, ... Tax 300 Tax2B Tax2B Tax 207 Tax300 D) Tax 154 Tax232 Tax1 Tax224 Tax 207 Tax207 Tax 184 Tax184 Tax154 Tax1 Tax1 Tax 154 Tax207 B) 60 Tax154 Transformation (Number) * 100 Tax1 A) http://www.retrovirology.com/content/6/1/83...

Ngày tải lên: 12/08/2014, 23:22

... research, and analyzed the data HH, KItoh, and JF designed the research, contributed vital new reagents, and analyzed the data TU analyzed the data, drafted the paper, and organized the research For production ... research, performed research, contributed vital new reagents, analyzed data, and wrote the paper ATK designed research, analyzed data, wrote the paper, and organized the research KS, KIo, and ... prepared the materials and performed a part of the research KIwai, HK, TS, MT, SI., and HA contributed vital new reagents YK contributed vital new reagents, performed a part of the research, and...

Ngày tải lên: 13/08/2014, 05:21

... 0.7s Điện áp pha a lưới u La (đường 3) có tần số f = 50hz, biên độ 220V Ta có kết dòng điện pha a máy phát cung cấp lưới isa (đường 4) sau:  Trong thời gian t < 0.5s : dòng điện pha a máy phát cung ... không thay đổi Điện áp pha a máy phát u sa (đường 5) đáp ứng trùng pha, trùng tần số, trùng biên độ với điện áp pha a lưới u La (đường 4) 3.2 Chế độ có tải Ở chế độ có tải, điện áp máy phát h a với ... dòng điện chạy qua, sức điện động rotor sinh hoàn toàn từ thông stator cảm ứng sang Từ trường stator quay với tốc độ góc ωs, rotor quay với tốc độ góc ω nên từ trường stator quay so với cuộn dây...

Ngày tải lên: 25/07/2015, 07:26

... AAGGGTTCGTGGAGCATGGG 3' ATGGTTGCAACTGGCAGTTTG 3' AGGACCTTTGAGCAACCAAG 3' AACGGCAGCGCCTTCTTGCT 3' GGCCCATGACCAGATCAGCA 3' ATGAGCTGCACCAGAATGATCC 3' TTGGTTGTGTGAGCACTTCC 3' ATGGAGGAGGACATTGATACC 3' ACATTGTATTCACCCCTACG ... ACATTGTATTCACCCCTACG 3' ATACGCCAGTGACGACCAGAGC 3' TAGCCCACACCATGAAAGCG 3' ATGGGAAGGTGAAGGTCGG 3' AAGACGCCAGTGGACTCCACGA 3' GTGGGGCGCCCCAGGCACCA 3' CTCCTTAATGTCACGCACGATTTC 3' 2.4.3.2 Quantitative ... TCTTGTAGCCCACGTTGTGG 3' CCCTGCTTCAGGCGTCTGTA 3' CATGCCATCTTCATCCACCT 3' GACCCGTGAGACAAAGAAGC 3' GCCCTCACACTTGACCAGTT 3' GAACTGCTATCGCATGGTCA 3' AACGTCTCCTGTGAGGATGG 3' AGTGGGCTGCGCGTCTCATTTTC 3' AAGGGTTCGTGGAGCATGGG...

Ngày tải lên: 09/09/2015, 18:52

... of Aurora -A, 234 ix Abbrevations aa A Box AD ADH AIK1 AKIP ALLM ALLN AML Amp APC/C ATP AURKA AZ AZI amino acid Aurora box Activation domain Alcohol dehydrogenase Human Aurora -A Kinase Aurora -A ... Aurora -A in vivo AKIP targets Aurora -A for protein destabilization in a proteasome-dependent manner AKIP- Aurora -A interaction is essential for the AKIP-mediated Aurora -A degradation Aurora -A ... cells Cancer Res (1998) 58(21):4811-6 27 Kamada K, Yamada Y, Hirao T, Fujimoto H, Takahama Y, Ueno M, Takayama T, Naito A, Hirao S, Nakajima Y Amplification/overexpression of Aurora -A in human gastric...

Ngày tải lên: 14/09/2015, 22:15

... required for RNA silencing in Neurospora, C elegans and Arabidopsis thaliana (Smardon et al., 2000; Cogoni and Macino, 1999; Dalmay et al., 2001; Dalmay et al., 2000b) Furthermore, small RNAs of ... from C elegans (Tabara et al., 1999), AGO1, AGO2 from Drosophila (Williams and Rubin 2002; Carmell et al., 2002) and AGO1, AGO4 from Arabidopsis (Fagard et al., 2000; Zilberman et al., 2003) ... a separate role that is associated with the systemic signaling of RNA silencing and RNA-directed DNA methylation in the nucleus Animals may also have a system for amplification and spread of...

Ngày tải lên: 16/09/2015, 17:11

... Cgs – Gate Source Capacitance of a MOS Transistor Cgd – Gate Drain Capacitance of a MOS Transistor Csb – Source Bulk Capacitance of a MOS Transistor Cdb – Drain Bulk Capacitance of a MOS Transistor ... the antenna has a much wider bandwidth than the baseband signal, it could essentially be modeled as a dipole antenna Thus, the baseband signal is differentiated by the antenna and the resultant ... ‘delay and add algorithm’ which delays the detected peaks by a pulse peak interval and adds it to the original waveform to form a wider pulse No accurate delay is needed here as although the digital...

Ngày tải lên: 26/09/2015, 09:39

... K, Yamaguchi T, Matsubara T, Takahashi T, Nakajima T, Muto T, Ikari T, Yanagisawa A, Kato Y: Proliferative activity of intrahepatic colorectal metastases after preoperative hemihepatic portal vein ... Kubota M, Matsuyama Y, Nakayama A, Miyagawa S, Makuuchi M, Kawasaki S: Preoperative portal vein embolization: an audit of 84 patients Hepatology 1999, 29:1099-1105 Page of (page number not for ... 21:434-439 Makuuchi M, Thai BL, Takayasu K, Takayama T, Kosuge T, Gunvén P, Yamazaki S, Hasegawa H, Ozaki H: Preoperative portal embolization to increase safety of major hepatectomy for hilar bile...

Ngày tải lên: 09/08/2014, 04:21

... explored for generating novel nanomaterials In the last decade several VBNPs have been examined for diverse applications such as templates for material synthesis, platforms for polyvalent display, ... Yamauchi N, Takahashi M, Sasaki K, Fukaura J, Neda H, Fujii S, Hirayama M, Itoh Y, Koshita Y, Kogawa K, Kato J, Sakamaki S, Niitsu Y: In vivo gene delivery to tumor cells by transferrinstreptavidin-DNA ... as a DNA-containing virus, the CPV capsid interior has natural affinity for viral single-stranded DNA and therefore lacks the capability to retain any of the nonspecifically packaged RNA, resulting...

Ngày tải lên: 11/08/2014, 00:22

... were diagnosed with facet pain Primary outcome measure was percent change in facet-related pain as measured by Visual Analog Scale (VAS) score at final follow-up visit Secondary outcome was change ... investigate the long-term efficacy of facet debridement for the treatment of chronic back pain originating in the facet joint MATERIALS AND METHODS Patient enrollment and evaluation All patients treated ... comparable to the more commonly used RFA, with results durable for at least years Larger scale trials with a control group are warranted to further evaluate the relative efficacy of this surgical...

Ngày tải lên: 26/10/2012, 09:32

... inverters can accommodate a wide range of input dc voltage for an improved energy output from variable wind turbine resources The input source and the output grid are separated based on flyback operation ... (DCM); the averaged current of Mode is the average output current of the inverter and can be expressed as, 230 vc is the capacitor voltage and is in the same order as the grid voltage The voltage stresses ... reference wave, serving as the modulating signal, is compared with a triangular wave, serving as the carrier signal The intersection points determine the switching angles and pulse widths as in Figure...

Ngày tải lên: 03/01/2014, 19:16

... 277 283 TSIPGVYACGDIVTYPGKLPLIVLGFGEAAIAANHAAAYAN-PALKVNPGHSSEKAAPGT TSIPGVFAAGDVMDHI YRQAITSAGTGCMAALDAERYLD GLADAK TSIPGIFAAGDCTSMWPGFRQVVTAAAMGAVAAYSAYTYLQEKGLYKPKPLTGLK *****::*.** : ... Toyobo (Osaka, Japan) Emulgen 911 was a gift from Kao Chemical (Tokyo, Japan) NADPH, NADH and NADP+ were purchased from Oriental Yeast (Tokyo, Japan) a- Cyano-4-hydroxycinnamic acid was obtained from ... :.:: : * : * NAYTAKAVIIAAGVGAFEPRRIGAPGEREFEGRGVYYAVKSKA-EFQGK-RVLIVGGGDS -EYTCDALIIATGASA -RYLGLPSEEAFKGRGVSACATCDG-FFYRNQKVAVIGGGNT LEVKARTVILAVGSRR -RKLGVPGEAELAGRGVSYCSVCDAPLFKGKDAVVVVGGGDS...

Ngày tải lên: 18/02/2014, 08:20