a novel diagnostic biomarker and therapeutic target for hepatocellular carcinoma

... 5a and b These metal nanoposts and nanoholes can be potentially applied into photonic crystals, and also for further processing using as metal masks Conclusions We have demonstrated a novel maskless ... produced a large area of highly uniform hexagonally packed gold nanoposts and nanoholes in gold thin film 123 using the uniform HCP nanoholes and nanopillars of photoresist for lift-off process, as ... maskless and self-aligned sub-wavelength photolithography technique for forming highly uniform arrays of nanoholes and nanopillars The technique utilizes the self-assembled property of microand nanospheres...

Ngày tải lên: 21/06/2014, 22:20

... 62 Ando E, Tanaka M, Yamashita F, Kuromatsu R, Takada A, et al Diagnostic clues for recurrent hepatocellular carcinoma: comparison of tumour markers and imaging studies Eur J Gastroenterol Hepatol ... Takayama T, Makuuchi M, Hirohashi S, Sakamoto M, Okazaki N, et al Malignant transformation of adenomatous hyperplasia to hepatocellular carcinoma Lancet 1990;336:1150-1153 17 47 Sakamoto M, Hirohashi ... Shimosato Y Early stages of multistep hepatocarcinogenesis: adenomatous hyperplasia and early hepatocellular carcinoma Hum Pathol 1991;22:172-178 48 Nakanuma Y, Terada T, Ueda K, Terasaki S,...

Ngày tải lên: 16/09/2015, 15:55

... type diabetes subjects Immunogenetics 2010, 62:101-107 36 Kawasaki E, Awata T, Ikegami H, Kobayashi T, Maruyama T, Nakanishi K, Shimada A, Uga M, Kurihara S, Kawabata Y, et al: Genetic association ... Health Center, 1650 Cedar Avenue, Montreal, H3G 1A4 , Qc, Canada Full list of author information is available at the end of the article thymic and peripheral CD4+ T cells in humans and mice, and ... Cobbold S, Alyanakian MA, Gouarin C, Barriot S, Garcia C, Waldmann H, Bach JF, Chatenoud L: Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic...

Ngày tải lên: 18/06/2014, 16:20

... [50]) Signs and Symptoms Abdominal abdominal pain, intestinal cramping and bloating, diarrhea and/ or obstipation, nausea, non-cardiac chest pain, Helicobacter pylori-negative gastritis, malabsorption ... prostaglandin D , and prostaglandin 9a, 11bPGF ) Together with a characteristic clinical presentation, abnormal markers can be of diagnostic, therapeutic and prognostic relevance However, it remains ... inhibitors for proven gastroesophageal reflux • Tachycardia⇒ verapamil; AT1-receptor antagonists; ivabradin • Neuropathic pain and paresthesia⇒ a- lipoic acid • Interstitial cystitis⇒ pentosan, amphetamines...

Ngày tải lên: 10/08/2014, 21:23

... Shirakawa T, Deichmann KA: Genetic variants of IL-13 signalling and human asthma and atopy Hum Mol Genet 2000, 9:549–559 39 Pauwels R: The relationship between airway inflammation and bronchial hyperresponsiveness ... necessary and sufficient to produce the TH2 response in vivo and is an important therapeutic target for allergic asthma Interleukin-9 promotes allergen-induced eosinophilic inflammation and airway ... indicating a role for IL-13 as a general enhancing factor on TH2 response Respiratory Research Vol No Zhou et al 31 Daniels SE, Bhattacharrya S, James A, Leaves NI, Young A, Hill MR, Faux JA, Ryan GF,...

Ngày tải lên: 12/08/2014, 18:20

... carcinoma, lung adenocarcinoma, in vitro and tumor ovarian cystadenocarcinoma, formation in mice colorectal carcinoma, renal cell (J.K Cheong et al, carcinoma, osteosarcoma and unpublished data) hepatocellular ... cutaneous and intracavitary superficial mucosal lesions such as vulvar intraepithelial neoplasia, cervical dysplasia or carcinoma in situ, oral cancer and nasopharyngeal bladder cavity mucosal surfaces, ... breast transformation adenocarcinoma cell lines MCF7 in vitro and tumor and ZR-75, human osteosarcoma formation in mice cell line SaOS-2 and human non(Darwish et al., small cell lung cancer cell...

Ngày tải lên: 12/09/2015, 08:19

... Peninsular Malaysia and the states of Sabah and Sarawak in the north of Kalimantan Kuala Lumpur, the national capital, Labuan UNEP/SCS – National Report Malaysia and Putra Jaya form the Federal territories ... the Straits of Malacca and the adjacent waters of the Andaman Sea and the Indian Ocean In the process, an attempt is made to identify, examine, and rank those threats that have transboundary effects ... coast of Peninsular Malaysia such as Sg Muda, Sg Pinang, Sg Perak, and Sg Klang are short and steep Open water bodies, natural wetlands, and manmade lakes such as dams, and ex-mining pools are...

Ngày tải lên: 06/03/2014, 15:21

... performed (maxima, minima, averages and standard deviation) for each of the variables In all cases the significance level used was 5% Crossed variables and bilaterally correlated analysis were also ... Miral s/n, 50009 Zaragoza, Spain Correspondence: Departamento de Psicolog a y Sociolog a Universidad de Zaragoza San Juan Bosco, 50009 Zaragoza (Espa a) E-mail: salavera@unizar.es ABSTRACT: Background: ... (Universidad de Zaragoza, Espa a) Departament de Psychology and Sociology Education Faculty, Zaragoza University, C/ San Juan Bosco, 50009 Zaragoza, Spain Physiotherapy Research Unit, Zaragoza University,...

Ngày tải lên: 11/08/2014, 16:21

... Jayaraman Krishnasamy, Mark J Jakiela, and Daniel E Whitney Mechanics of vibration-assisted entrapment with application to design In International Conference on Robotics and Automation IEEE, April ... comparison of quasi-static algorithmic and Monte Carlo simulated approaches to physical experiments [13] Krishnasamy, Jakiela, and Whitney analyzed vibration-assisted entrapment of both simulated ... Research, 7(1):4–17, February 1988 Also appeared in Proceedings of the IEEE International Conference on Robotics and Automation, April 1986 [6] Alan D Christiansen, Andrea D Edwards, and Carlos A...

Ngày tải lên: 03/01/2014, 19:15

... in a strip a few feet wide at the perimeter of the lawn at any areas adjacent to woods and underbrush Also treat any ornamental shrubs near the house that may serve as a habitat for small animals ... yeast here will ferment dietary sugars and starches, forming acids, gas, alcohols and a variety of organic chemicals Symptoms include gas, bloat, heartburn and/ or pain in the stomach area, and ... thyroid, measure free T3 and free T4 levels and TSH, and nuclear scanning and testing for autoantibodies may be necessary Activation of the inflammatory cascade has been implicated in blockade of...

Ngày tải lên: 05/03/2014, 10:20

... moving average method (Vlachos The news articles in one day is treated as a batch 44 et al., 2004) ,we parameterize p0 and p1 with the time index for each batch, formally, we have p0 (t) and p1 ... frequency state q1 Each state has its own emission rate (p0 and p1 respectively), and there is a probability for changing state If an interval of high states appears in the optimal state sequence ... Nj,w and Nj are w ’s document frequency and the total number of documents in jth batch respectively s is a scaling factor lager than 1.0, indicating state q1 has a faster rate, and it is empirically...

Ngày tải lên: 23/03/2014, 14:20

... decreased in a subsequent reaction and finally caused complete degradation (Fig 1B,C) indicating that and 10 are fairly good substrates for endo-b-galactosidase and reflect an Nacetyllactosamine-repeating ... the same way, compound was obtained in a 71% total yield (13.2 mg) based on the acceptor from and UDP-Gal H and 13C-NMR data of and are summarized in Table Preparation of GlcNAcb1-3Galb1-4GlcNAcb-pNP ... UDP-GlcNAc and UDP-Gal were kind gifts from Yamasa Corporation (Choshi, Japan) All other chemicals were obtained from commercial sources Enzyme assay b-D-Galactosidase, b-D-glucosidase and b-NAHase activities...

Ngày tải lên: 31/03/2014, 07:20

... 113 Afghanistan Albania Algeria American Samoa Andorra Angola Anguilla Antigua and Barbuda Argentina Armenia Aruba Australia Austria Azerbaijan Azores Bahamas Bahrain Bangladesh Barbados Belarus ... Bermuda Bhutan Bolivia Bosnia and Herzegovina Botswana Brazil British Virgin Islands Brunei Darussalam Bulgaria Burkina Faso Burundi Cambodia Cameroon Canada Cape Verde Cayman Islands Central African ... 416 Afrikaans Albanian Amharic Arabic Armenian Assamese Azeri Bashkir Basque (Euskara) Belarusian Bemba Bengali Berber Bhili Bikol Bulgarian Burmese Buyi Catalan Cebuano (Visayan) Chichewa Chinese...

Ngày tải lên: 02/04/2014, 05:20

... by a grant from the Canadian Arthritis Network (a National Centre of Excellence) Dr Marra is supported by a Canadian Arthritis Network Scholar Award, and a Michael Smith Foundation for Health ... comes from a scoring formula which is typically based on preferences for health states from a general population sample Direct methods include the visual analog scale (VAS), and standard gamble (SG) ... determine quality of life of an individual are captured and summarized as a global score In VAS and SG valuation methods, however, the individual evaluates his or her own health state based on a holistic...

Ngày tải lên: 20/06/2014, 15:20

... correlated fading, in IEEE VTC 3, 2050–2054 (1997) 27 A Akansu, M Tazebay, M Medley, P Das, Wavelet and subband transforms: fundamentals and communication applications IEEE Communications Magazine ... partitioning of PO-CI and odd/even separation of available subcarriers are useful in adding extra users and hence the system capacity In multimedia communication, users transmit at variable data ... for multirate CI/MC-CDMA system The performance is compared with Block-PIC and Sub-PIC with hard and soft estimates of received data bits over AWGN and frequency selective Rayleigh fading channels...

Ngày tải lên: 20/06/2014, 22:20

... design and coordination, as well as in sample preparation and characterization by TEM, SEM and SAXS NV participated in TEM observations and in spectroscopic measurements CS, AL-Q and TI participated ... Universidad de Santiago de Compostela, Santiago de Compostela, 15782, Spain 5Toyota Physical & Chemical Research Institute, Nagakute, Aichi, 4801192, Japan Additional material Additional file ... to a Bragg spacing d of 3.8 nm (see Figure S2 in Additional file 1); the lattice parameter for a hexagonal array (a = 2d/√3) was calculated as 4.4 nm, which is similar to that of MCM-41 silica...

Ngày tải lên: 21/06/2014, 04:20

... control-oriented functionality (an ARM for the signalling part and a StarCore for the multimedia part) It features several hardware accelerating units (ASICs), for the more data-oriented and computation intensive ... directed acyclic graph (DAG) The objective function incorporates several constraints on the available silicon area (hardware capacity), B Knerr et al memory (software capacity), and latency as a timing ... constraints like time, area, power, throughput, delay, and so forth Hardware then usually addresses the implementation of a functional part, for example, performing an FIR or CRC, as a dedicated hardware...

Ngày tải lên: 22/06/2014, 06:20

... allocation scheme is used as the channel state information (CSI) is not available at the transmitter If the average attenuation of the channel for each cooperative node pair can be estimated, ... perform data aggregation to remove the redundancy in the data After aggregating received data frames, the cluster head will forward the data packet to the TCH by multiple hops routing In each ... spectral density, Pb is the desired BER performance, Gt and Gr are the transmitter and receiver antenna gains, respectively, also, λ is the carrier wavelength [2] The training overhead and transmission...

Ngày tải lên: 22/06/2014, 22:20

... Gerry Abbot, Richard Fay, Clare West and Pam Murphy for their comments on the manuscript Sue Andre and Paul Heacock for their help with the appendix on American English Amanda MacPhall for the ... (but not 'have got') is also used for many actions and experiences For example: have breakfast/dinner /a cup of coffee /a cigarette etc have a bath /a shower /a swim /a rest /a party /a holiday /a nice time ... middle- and upper-intermediate levels (where all or nearly all of the material will be relevant), and can serve both as a basis for revision and as a means for practicing new structures It will also...

Ngày tải lên: 06/07/2014, 23:20

... hierarchical namespace, and new feature names can be registered with IANA This means that any developer can create new features in SIP, and then simply register a name for them Compatibility ... contacts the callee, the callee can redirect the caller to a number of different locations Each of these locations can be an arbitrary URL, and contains additional information about the terminal ... transfer, operator assisted transfer, three-party calling, bridged calling, dial-in bridging, multi-unicast to multicast transitions, ad-hoc bridge invitation and transition, and various forwarding...

Ngày tải lên: 08/07/2014, 17:03