a function of managerial skills and leadership

... disintegrated, and Icarus plunged to his death in the water that now bears his name, the Icarian Sea The tale of Icarus parallels a story I have watched unfold again and again among passionate entrepreneurs ... without adequate awareness or preparation, where unexamined assumptions and unnecessary risks are widespread, and where the personal, financial, and professional stakes of launching a new venture are ... personally and professionally, I can point to lessons from each that have been indispensable, and also, for American Management Association • www.amanet.org Introduction xix each, I can point to aspects...

Ngày tải lên: 15/02/2017, 08:10

... Itakura E, Mizushima N (2010) Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins Autophagy 6: 764-776 [11] Axe EL, Walker SA, Manifava M, Chandra ... Chapter Autophagy, the “Master” Regulator of Cellular Quality Control: What Happens when Autophagy Fails? 81 A Raquel Esteves, Catarina R Oliveira and Sandra Morais Cardoso Chapter Altering Autophagy: ... Autophagic Balance Between Mammals and Protozoa: A Molecular, Biochemical and Morphological Review of Apicomplexa and Trypanosomatidae Infections 289 Thabata Lopes Alberto Duque, Xênia Macedo...

Ngày tải lên: 17/03/2014, 12:20

... after days of withdrawal of usual medication Lequesne's Functional Index score greater than points after days of withdrawal of usual medication Ability to walk Availability for the duration of ... in pain and physical function scores at baseline and on days 7, 30, 60 and 90 of treatment and serum MMP-3 levels at baseline and on day 90 of treatment Pair-wise changes were examined by carrying ... exhibited better AKBA bioavailability than 5-Loxin® in Wistar rat model Broad spectrum safety of Aflapin was also established in a battery of acute and sub-acute toxicity studies in rat and rabbits These...

Ngày tải lên: 25/10/2012, 11:40

... involves an acidic residue acting as a general acid ⁄ general base and a di-nuclear metal center participating in binding the substrate and stabilizing the transition state [2,14,35–37] The main data ... griseus A Fig Rate ratio (Vn ⁄ V1) as a function of atom fraction of deuterium (n) for SGAP and its mutant E131D Vn is the kcat value obtained at a particular fraction of deuterium (n), whereas V1 ... Yatsushiro S, Tsuboi S, Iwabuchi M & Hatanaka T (2006) Modulation of Streptomyces leucine aminopeptidase by calcium: identification and functional analysis of key residues in activation and stabilization...

Ngày tải lên: 19/02/2014, 02:20

... protein can be compared with over 50 homologs found in known bacterial genomes, and in Arabidopsis thaliana and Spinacia oleracea plant sequences A search using FASTA [34] and BLAST [35] revealed ... (Fig 5) Amino acids 52–53 are spatially close to the loop a1 -b2 with distances of ˚ ˚ 4.6 A and 6.2 A from Ca atoms of Thr52 and Ile53 to Ca atom of Pro36, respectively, and are probably affected ... 0.14 A for ˚ backbone heavy atoms (N, Ca, C¢), and 1.19 ± 0.15 A for all heavy atoms Ramachandran analysis was used to confirm the good quality of the structure Of the residues, 81.4% have backbone...

Ngày tải lên: 17/03/2014, 10:20

... determined and the mean of the total areas was calculated for each group The Mean and SD of bladder tumor area (A) and weight (B) are shown Amit and Hochberg Journal of Translational Medicine 2010, ... area of the malignant tissue of each bladder was determined by ImagePro Plus software Another healthy mice were used as control The total tumor area of each bladder was determined and the mean ... activation was reported as a major mechanism for the IGF2 overexpression in a variety of tumors including bladder carcinoma, hepatocellular carcinoma, breast cancer, ovarian cancer and prostate cancer...

Ngày tải lên: 18/06/2014, 16:20

... interval was the measured variable Statistics Means and standard deviations were calculated for age, height and mass and for the dependant variables derived from the functional assessment, quadriceps ... imbalance and joint instability Berman et al [25] reported that patients with near normal quadriceps strength at minimum of years after surgery had a more normal gait Silva et al [27] Page of ... Surgery, Clinical Medical School, University of Queensland, Australia 2Royal Brisbane Hospital, Australia, Department of Orthopaedic Surgery, Medical School, University of Queensland, Australia Centre...

Ngày tải lên: 20/06/2014, 04:20

... interval was the measured variable Statistics Means and standard deviations were calculated for age, height and mass and for the dependant variables derived from the functional assessment, quadriceps ... imbalance and joint instability Berman et al [25] reported that patients with near normal quadriceps strength at minimum of years after surgery had a more normal gait Silva et al [27] Page of ... Surgery, Clinical Medical School, University of Queensland, Australia 2Royal Brisbane Hospital, Australia, Department of Orthopaedic Surgery, Medical School, University of Queensland, Australia Centre...

Ngày tải lên: 20/06/2014, 07:20

... BGP and MW designed the study protocol, organized and carried out the original study, and took part in the acquisition of data and their analysis and interpretation All authors read and approved ... FW, Ballard ED, Huang B, Samra NK, Lansoprazole Asthma Study Group: Effects of 24 weeks of lansoprazole therapy on asthma symptoms, exacerbations, quality of life, and pulmonary function in adult ... GER-related asthma [30], laryngopharyngeal reflux [31], and for rheumatoid arthritis and arthrosis treated with nonsteroidal anti-inflammatory drugs (NSAIDs) [32] The favorable effect of PPIs on many...

Ngày tải lên: 20/06/2014, 15:20

... Jiangsu Laboratory of Advanced Functional materials and College of Physics and Engineering, Changshu Institute of Technology, Changshu 215500, China 2Department of Theoretical Chemistry, School of ... Spin-polarized current and spin accumulation in a three-terminal two quantum dots ring Appl Phys Lett 2008, 92:172104-172106 41 Uchida K, Takahashi S, Harii K, Ieda J, Koshibae W, Ando K, Maekawa S, ... state and an asymmetrical Fano line shape centered at the antibonding molecular state The degree of the asymmetry of the Fano-Like peak can be attributed to the electron phase coherence In the table...

Ngày tải lên: 20/06/2014, 23:20

... Fix T such that Ax, x − x ≥ 0, ∀x ∈ Fix T , 1.7 a variational inequality studied by Yamada and Ogura 10 A Example 1.3 Let A be a maximal monotone operator Taking T Jλ : I A −1 and P I − γ∇ψ, ... Muglia, and Y Yao, “On a two-step algorithm for hierarchical fixed point problems and variational inequalities,” Journal of Inequalities and Applications, vol 2009, Article ID 208692, 13 pages, ... pages, 2009 F Cianciaruso, V Colao, L Muglia, and H.-K Xu, “On an implicit hierarchical fixed point approach to variational inequalities,” Bulletin of the Australian Mathematical Society, vol...

Ngày tải lên: 21/06/2014, 07:20

... derivatives of radial homogeneous and logarithmic functions,” Communications in Mathematical Analysis, vol 9, no 2, pp 51–66, 2010 K Morii, T Sato, and H Wadade, “Br´ zis-Gallou¨ t-Wainger type inequality ... 1964 15 A Lunardi, Analytic Semigroups and Optimal Regularity in Parabolic Problems, vol 16 of Progress in Nonlinear Differential Equations and their Applications, Birkh¨ user, Basel, Switzerland, ... Equation 3.19 is a simple but delicate inequality, since we need to take a full advantage of the definition of 1.3 and the equality ∇uj x log j − j x ϕ0 2l |x| |x|2 l 3.23 Also, a direct calculation...

Ngày tải lên: 21/06/2014, 11:20

... Wang and T.-S Yeh, “Exact multiplicity of solutions and S-shaped bifurcation curves for the p-Laplacian perturbed Gelfand problem in one space variable,” Journal of Mathematical Analysis and Applications, ... Marcos, Tex, USA 10 J R Parks, “Criticality criteria for various configurations of a self-heating chemical as functions of activation energy and temperature of assembly,” The Journal of Chemical ... in Mathematical and Computational Biology, John Wiley & Sons, Chichester, UK, 2003 R S Cantrell and C Cosner, “Density dependent behavior at habitat boundaries and the Allee effect,” Bulletin of...

Ngày tải lên: 21/06/2014, 16:20

... Journal of Inequalities and Applications 13 S S Dragomir, R P Agarwal, and N S Barnett, “Inequalities for beta and gamma functions via some classical and new integral inequalities,” Journal of ... gamma and incomplete gamma functions,” Journal of Inequalities and Applications, vol 2006, Article ID 48727, pages, 2006 Y Yu, “An inequality for ratios of gamma functions,” Journal of Mathematical ... bb /aa , L a, b b − a / log b − log a , and G a, b L−2 a, b ab the arithmetic mean, identric L−1 a, b mean, logarithmic mean, and geometric mean of a and b with a / b, respectively, then min {a, ...

Ngày tải lên: 22/06/2014, 02:20

... gia nhiệt cho dầu chảy bên ngòai ống khơng gian hình xuyến, sau nước lạnh bơm tuần hòan thơng qua Collector thu nhiệt mặt trời vào tank ch a nhỏ Dầu thơ tuần hòan khơng gian hình xuyến qua quay ... 23, mở van 12, 14 , 15, 16, 17, 19, 20, hai bơm 5A họat động, lúc nước nóng tank lớn gia nhiệt cho tank nhỏ qua dàn ống xoắn để từ nước nóng bên đường ống thiết bị ống lồng ống để gia nhiệt cho ... gia nhiệt thêm cho dầu có họat động hay khơng phụ thuộc vào nhiệt độ dầu vỏ ngòai khơng gian hình xuyến trao đổi nhiệt ống lồng ống, tùy thuộc vào điều kiện thời tiết Điện trở sấy dầu (10) họat...

Ngày tải lên: 29/06/2014, 16:20

... statistical analysis IK performed the follow-up of the trial and the radiographic study, and data management BM, TS and EV significantly contributed to devising the protocol, analysis of data and ... trial) to be read was indicated by a mark made by those in charge of randomization and labelling of radiographs Readings were done between 24 August 2004 and October 2004 by the two readers Measurement ... to the American College of Rheumatology criteria [20]), who were 45–75 years old and who had a manually measured JSW on plain AP pelvic radiograph of 1–4 mm at baseline All patients gave written...

Ngày tải lên: 09/08/2014, 07:20

... urine and whole blood of all patients at each visit of the study duration (Table 3) Serum biochemical parameters and haematological parameters were measured using the automated analyzer HumaStar ... some of the parameters, they remained within the normal laboratory range Statistical analyses of these parameters did not identify any statstically significant changes Similarly, haematological and ... the ancient herb Boswellia serrata has gained much attention as a potent antiinflammatory, anti-arthritic and analgesic agent [10,11] 3-Oacetyl-11-keto-beta-boswellic acid (AKBA) is the most active...

Ngày tải lên: 09/08/2014, 10:23

... Heart Lung Transplant 1999, 18:814-817 32 Tayama E, Ueda T, Shojima T, Akasu K, Oda T, Fukunaga S, Akashi H, Aoyagi S: Arginine vasopressin is an ideal drug after cardiac surgery for the management ... regarding the general characteristics (sex, mean age, and BSA), clinical preoperative data (co-morbidity, severity of CAD and intraoperative hemodynamic measurements), preoperative medication and ... preoperative medication, Biometric data such as age and BSA, Page of 12 Some intraoperative factors such as cardiopulmonary bypass-time and ischemia-time, The units of administered blood and/ or...

Ngày tải lên: 10/08/2014, 10:20

... disastrous renal infarction and subsequent functional impairment Murakami et al also reported a 77-year-old patient with an AAA associated with a CSPK, which was supplied by two aberrant renal arteries ... AAA Kaplan et al first presented a patient with a single renal artery arising from the right common iliac artery [7] The AAA was successfully repaired endoluminally with a tube stent graft, and ... a 59-year-old patient revealed an asymptomatic abdominal aortic aneurysm, and a solitary pelvic kidney, and the composition of the renal vasculature One renal artery originated from the aortic...

Ngày tải lên: 11/08/2014, 00:22

... challenge But since the clinical history, examination, upper gastrointestinal endoscopy and barium swallow X-ray were suggestive of achalasia cardia, a final diagnosis of achalasia cardia was ... have a poor sensitivity and specificity in the diagnosis of achalasia, it has an important role in ruling out secondary causes of achalasia (i.e pseudoachalasia) A chest X-ray can give important ... AK, Shafqat E, Malik K, Amin J: Achalasia esophagus; presenting as acute air way obstruction J Pak Med Assoc 2007, 57(8):423-425 Sharma GL, Kumar A, Mukund A, Kedia A: Atypical presentation of...

Ngày tải lên: 11/08/2014, 19:21