... removal of intravenous lines) The observers were not involved in the daily care ofthe patients, and ICU physicians were not aware of this part ofthe observation As a consequence, theclinical ... look for other infections, and the absence of radiological signs of pulmonary congestion might have resulted in another fluid therapy regimen We did not score for theclinical relevance ofthe unexpected ... antimicrobial therapy in case of unexpected infiltrates on the CXR; repositioning of tubes in case of malposition of orotracheal tubes (ignoring planned extubations); ultrasound ofthe thorax in case of...
... atypical presentationof PIDs During the course of investigation, we found the proband's grandmother (III:1) had died of non-Hodgkins lymphoma at 51 years of age Lymphoma is one ofthe classical presentations ... Mutations in the SH2D1A [19] and XIAP [20] genes have been identified as the cause of these syndromes The initial study ofthe proband described above was undertaken in Perth during the time the assay ... family, there are no other male patients at risk of XLP Prognosis Another patient with no family history of recurrent infections presented with a monoarthritis of his knee at the age of At the time...
... carcinomawere compared with the group of 10,061 cases, mostly ofthe invasive ductal type (91% of cases), observed during the same period The focus ofthe study was the comparison of ductal carcinomas ... that a total of 23 patients had MRI ofthe breast On further review of these pathology cases, there were 12 patients with mixed ductal/lobular carcinoma who had MRI ofthe breast We then compared ... presence in the ductal and lobular component ofthe tumor Although the E-cadherin staining is weaker in the lobular regions ofthe tumor, it is nonetheless present Overall, 90% (6/7) ofthe cases...
... linked with the former precipitating the latter Conclusion Our case illustrates the need for extra vigilance to make the diagnosis of splenic rupture in the context of a lack of trauma The exact ... [4]) The investigation of choice for confirming the diagnosis is computed tomography (CT) ofthe abdomen [5], which has a sensitivity and specificity of 90-95% Splenectomy remains the treatment of ... case report of SSR in association with lung cancer Lung cancer with splenic rupture has been reported either in the context of splenic metastasis [8], after the initiation of chemotherapy in a...
... ofthe pericardial tissue demonstrated that the vast majority ofthe lymphocytes were CD5 (+) (Figure 3) and CD20 (+) B-cells, with a minority of lymphocytes being CD3 (+) T-cells Together, the ... because the diagnosis of leukemia was unknown, pericardiocentesis was performed without chemotherapy and has provided sustained relief of her dyspnea for the past year Conclusion To the best of our ... this is the first reported case of CLL presenting as pericardial tamponade The diagnosis was confounded by the similarities to tuberculous pericarditis and the modest degree of leukocytosis The appearance...
... ofthe pericardial tissue demonstrated that the vast majority ofthe lymphocytes were CD5 (+) (Figure 3) and CD20 (+) B-cells, with a minority of lymphocytes being CD3 (+) T-cells Together, the ... because the diagnosis of leukemia was unknown, pericardiocentesis was performed without chemotherapy and has provided sustained relief of her dyspnea for the past year Conclusion To the best of our ... this is the first reported case of CLL presenting as pericardial tamponade The diagnosis was confounded by the similarities to tuberculous pericarditis and the modest degree of leukocytosis The appearance...
... years of age while in the mild form theclinical features appear in the second decade of life In the severe form there is severe mental retardation and loss of skills Death usually occurs in the ... usually made in the second decade of life Death usually occurs in the fourth decade and the main cause of death is cardiac failure Diagnosis ofthe disease is usually made by clinicalpresentation ... collected the data and drafted the paper GSS helped in the acquisition of significant intellectual content and the revision ofthe manuscript The final manuscript was approved by all the authors...
... performed The surgical specimen included a bluish mass localized in the head ofthe pancreas Pathology and immunohistochemistry ofthe tumor revealed a SPT The postoperative course ofthe patient ... becomes clinically evident as a palpable mass at the epigastrium, the left or the right hypochondrium [2] Furthermore, pain can also be the first sign of a SPT [2] To our knowledge, this is the first ... on the location ofthe tumor, represent the procedures of choice [2] The mean size of SPTs is 6.08 cm, so the tumor in this case is classified as small Conclusion In our case, the most noteworthy...
... sequenced for the identification ofthe H275Y mutation in the NA gene The sequencing results demonstrated that 2.5% ofthe 2007-2008 isolates and 100% of 2008-2009 isolates had the H275Y mutation ... analyses The extraction of viral RNA and cDNA synthesis using random primers were performed as described previously [21,22] The cDNA was then used as the template for the amplification ofthe HA ... Phylogenetic trees for the HA gene of A(H1N1) viruses The region from nucleotide 33 to 1102 (1070 nucleotides) for the HA gene were used for the analysis The numbers below the branches are the bootstrap...
... responsible for the unique clinical features of BD The lack of individual demographic data ofthe controls might be one ofthe limitations of this study Nevertheless, we believe that the results of our ... between HLA-A alleles and clinical features of BD in HLA-B*51 non-carriers To eliminate the effect of HLA-B*51 on theclinical manifestations of BD (Additional file 1), the analysis was performed ... detect the nucleotide sequences ofthe PCR product at polymorphic sites of HLA-A gene At the same time, the biotinylated PCR product was labeled with Results Clinical characteristics of BD patients...
... progression ofthe disease and the interval between the onset of Raynaud’s phenomenon (RP) and SSc is short [2,5], the time course ofthe onset of RP and SSc has not been well described In the present ... all ofthe SSc patients had RP during the course ofthe disease regardless ofthe autoantibody specificity However, only of 17 anti-RNAP III positive patients did not have RP by the time of initial ... of medicine Informed consent, including the publication ofthe study, was obtained from all patients according to the Declaration of Helsinki Immunoprecipitation Autoantibodies in sera from the...
... determine whether the facet joints were the source of pain These included injection of local anaesthetic into the joint itself or the nerves that innervate them, resulting in relief from pain if the pain ... has not yet been discovered [7] In the case of 'facet syndrome', the source of pain is identified but theclinicalpresentation is poorly defined Nevertheless, the term is widely used and a Medline ... on each of four topics relating to thepresentationof pain: location, severity, aggravating factors, and relieving factors The choice of these keywords was left entirely to the groups The authors...
... difference favouring the intervention group of SMD -0.44 (95% CI: -0.66, -0.23) Vote Counting The results ofthe vote-counting supported the results ofthe meta-analysis Of 170 child behaviour ... conduct problems Further no existing reviews have attempted to compare the relative effectiveness of different types of programmes The objective ofthe current study was therefore to systematically ... if: (a) they were RCTs, (b) the population comprised parents/carers of children up to the age of 18 where at least 50% had a conduct problem (defined using objective clinical criteria, the clinical...
... outcome The degree ofthe changes ofthe DWI and the ADC signal intensity correlates with the severity of neuronal injury because modest changes reflect signs of ongoing lesions, and a severe drop of ... not homogeneous in the different regions of Table Prediction of unfavourable outcome using the optimal cutoffs ofthe ADC and the percent ADC Grey matter structures Optimal cutoff ADC Sensitivity ... to determine clinical outcome ofthe comatose patients after out -of- hospital cardiac arrest In addition, there was a relationship between the GOS and the regional ADC values ofthe grey matter...
... find a complete affection ofthe dermatome representing the C6 level and neither ofthe dermatomes below this level In the absence of cervical pain, and motor dysfunction, the underlying cause was ... fracture at the ventral base plate of C5 The CT The CT scan shows the small teardrop fracture at the ventral base plate of C5 The ruptured disc cannot be clearly identified Page of (page number ... deceptive the situation may appear to the emergency physician Theclinicalpresentation in this case was rather unusual A patient with a cord injury typically has pain at the site ofthe spinal...
... in three cases, all of them belonging to the placebo group The duration of MV was 13 days (IQR to 26 days) for the placebo group and days for the only case in the MPDN group The differences not ... another two patients from the placebo group and one in the MPDN group were transferred to ICU Of these nine patients, three developed septic shock, two of them were from the placebo group The ... methyl-prednisolone presenting CAP of different levels of severity, concluded that the corticoid treatment did not improve the outcome ofthe episodes Nevertheless, in this study the percentage of severe episodes...
... bedclothes A detailed appraisal ofthe pattern of spasticity may enable the individual to relieve many ofthe functional problems Both the clinician and the individual should be aware of potential ... describe the problems in different circumstances are of far more value than a single examination in the outpatient clinic Clinical consequences The above description ofthe different patterns ofthe ... spasticity The following chapters in the book outline the detail ofthe different approaches to the management, but this section attempts to provide an overview ofthe process (Fig 1.1) Aims of treatment...
... inform the cerebellar cortex ofthe place and rate of movement ofthe limbs These fibers put the motor intention generated by the cerebral cortex into the context ofthe status ofthe body at the ... cortices.76 The medial prefrontal region is involved in the explicit representation of states ofthe self Along with the temporal region’s representation ofthe intentional actions of others, the two ... direction of force.14 The direction of an upper extremity movement may be coded by the sum ofthe vectors ofthe single cell activities in motor cortex in the direction ofthe movement.40 The activity...
... impact on the form and integrity of all other parts The Chinese were well aware of all these issues as evidenced by their recognition ofthe effect ofthe weather and seasons on the balance ofthe ... from the apothecaries and the allopathic doctors ofthe old school In 1846 the American Medical Association (AMA) was formed to counter the influence ofthe homeopaths and the AIH By the turn ofthe ... 213 The Law of Similars .213 The Law ofthe Minimum Dose 213 The Totality of Symptoms 214 The Law ofthe Single Remedy 214 The Law of Cure ...
... its equilibrium position by the energy of a passing sound wave because ofthe interaction ofthe elastic forces ofthe air and the inertia ofthe air particle Direction of wave travel A Water surface ... frictional losses in the spring, because ofthe elasticity ofthe spring and the iner- the air, etc tia ofthe weight The weight in Fig 1-1 moves in what is called simple harmonic motion The piston in ... The Ear and the Perception of Sound 41 Sensitivity ofthe Ear 41 A Primer of Ear Anatomy The pinna: Directional encoder of sound Directional cues: An experiment The ear canal The middle ear The...