4 single nucleotide polymorphism snp analysis
Báo cáo y học: "Translational Medicine and Reliability of Single-Nucleotide Polymorphism Studies: Can We Believe in SNP Reports or Not"
... [13, 14, 16,19,20,23, 24, 26-28,31,36,37,39 -41 ,45 ,46 ,48 ,50,5 3,56,60-62, 64, 65,68,69,72- 74, 76-79,81,89,91] and 40 more than polymorphisms [15,17,18,21,22,25,29,30, 32-35,38 ,42 -44 ,47 ,49 ,51,52, 54, 55,57-59,63,66,67,70,71,75 ... 16.375) 3.51 (4. 37) 2.00 (0 – 17.33) 2.39 (2.85) 1. 14 (0 – 8.33) 3.80 (4. 54) 1.95 (0 – 17.33) 3.17 (3.99) 1.67 (0 – 16.375) 3. 74 (4. 48) 2 .40 (0 – 17.33) 4. 52 (5 .44 ) 2. 04 (0 – 17.33) 2.71 (3 .43 ) 1.38 ... polymorphisms tested ( 24) 19 (76) 1-3 polymorphisms tested > polymorphisms tested GSTP1 Ala114Val 11 (46 ) (27) 13 ( 54) 24 (73) 0. 147 1-3 polymorphisms tested (100) (0) 0.286 > polymorphisms tested...
Ngày tải lên: 25/10/2012, 10:51
Tài liệu Báo cáo khoa học: Fra-1 targets the AP-1 site/2G single nucleotide polymorphism (ETS site) in the MMP-1 promoter docx
... promoter polymorphism 1G/2G is correlated with colorectal cancer invasiveness Clin Cancer Res 7, 2 344 –2 346 Zhu, Y., Spitz, M.R., Lei, L., Mills, G.B & Wu, X (2001) A single nucleotide polymorphism ... Fra-1 and the 2G SNP (Eur J Biochem 270) 42 17 Fra-1 has been implicated in the regulation of MMP-1 [37 40 ], MMP-13 [41 ,42 ] and the urokinase plasminogen activator receptor [43 ], a receptor in ... Endocrinol 170, 41 –56 46 Bakiri, L., Matsuo, K., Wisniewska, M., Wagner, E.F & Yaniv, M (2002) Promoter specificity and biological activity of tethered AP-1 dimers Mol Cell Biol 22, 49 52 49 64 47 Benbow,...
Ngày tải lên: 21/02/2014, 00:20
Báo cáo sinh học: " Toll-like receptor 4 single-nucleotide polymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomas" potx
... 61 ± 10 55 (0-129) 57 ± 43 (9-98) 0.13 0.38 44 /7 11/0 0.33 Smoking; n (%) 54 (87.1) 43 ( 84. 3) 11 (100) 0.33 Mean pack years ± SD 50 ± 20.3 48 .9 ± 20.3 54. 1 ± 21.1 TLR4 Total expression 11 (17.7) ... 138 for analysis of TLR4 Asp299, a group of 62 for analysis of TLR4 Thr399 (39 patients were analyzed for both SNPs), and a group of 78 patients with HNSCC for TLR4 expression analysis (43 /78 were ... therapy TLR4 Asp299Gly (rs4986790) (45 .4) (3.9) (27.3) AJCC stage I; n (%) 1 11 10 (19.6) (9.1) 15 12 II; n (%) 16 14 (27.5) (18.2) 3 1.00 < 0.01 III; n (%) (5.9) ( 54. 5) IVA; n (%) 25 23 (45 .1) (18.2)...
Ngày tải lên: 18/06/2014, 22:20
báo cáo hóa học:" Toll-like receptor 4 single-nucleotide polymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomas" doc
... 61 ± 10 55 (0-129) 57 ± 43 (9-98) 0.13 0.38 44 /7 11/0 0.33 Smoking; n (%) 54 (87.1) 43 ( 84. 3) 11 (100) 0.33 Mean pack years ± SD 50 ± 20.3 48 .9 ± 20.3 54. 1 ± 21.1 TLR4 Total expression 11 (17.7) ... 138 for analysis of TLR4 Asp299, a group of 62 for analysis of TLR4 Thr399 (39 patients were analyzed for both SNPs), and a group of 78 patients with HNSCC for TLR4 expression analysis (43 /78 were ... therapy TLR4 Asp299Gly (rs4986790) (45 .4) (3.9) (27.3) AJCC stage I; n (%) 1 11 10 (19.6) (9.1) 15 12 II; n (%) 16 14 (27.5) (18.2) 3 1.00 < 0.01 III; n (%) (5.9) ( 54. 5) IVA; n (%) 25 23 (45 .1) (18.2)...
Ngày tải lên: 20/06/2014, 04:20
Báo cáo y học: "Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients" potx
... high-resolution genotyping was performed to define the shared epitope (SE) positive DRB1* 04 alleles * 040 1, * 040 4, * 040 5 and * 040 8 In the ethnically very homogenous German population, the alleles DRB1*0102 ... (1.88–3.79) RF- (n = 99) 29.3 (29) 35 .4 (35) 2.3a (1 .42 –3.72) CCP+ (n = 193) 34. 7 (67) 38.3 ( 74) 2.62a (1.78–3.86) CCP- (n = 65) 35 .4 (23) 38.5 (25) 2.63a (1.52 4. 56) Values are the frequency in ... CT/TT (n = 45 ) P value (0–2.5) (0 4. 7) 0.612 2.0 (0–12.2) 11.5 (0–20.0) 0.061 Larsen score after years 10.0 (0–26.0) 18.5 (2.0– 34. 5) 0.076 Larsen score after years 16.0 (2.0–30.0) 24. 0 (4. 7 41 .5)...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity" doc
... CT 0.26 (95) TT 0.05 (18) Control CC 0.57 ( 141 ) CT 0 .40 (98) TT 0. 04 (9) Case AA 0.81 ( 244 ) AG 0.15 (46 ) GG 0.03 (10) Control AA 0.78 ( 146 ) AG 0.22 (41 ) GG 0.005 (1) Case CC 0.77 (395) CT 0.22 ... http://arthritis-research.com/content/9/5/R98 Figure Haplotype blocks in NCF4 Three haplotype blocks were identified in NCF4 Block contains the associated single nucleotide polymorphism (SNP) NCF4 rs729 749 Colour scheme of the linakge ... selected 67 SNPs, 51 were successfully turned into assays Six SNPs failed to make good assays (rs1 049 255 [CYBA], rs699 244 , rs789180, rs4652813 and rs6667363 [NCF2], and rs2075938 [NCF4]), whereas...
Ngày tải lên: 09/08/2014, 10:21
Báo cáo y học: "Association of a single nucleotide polymorphism in growth differentiate factor 5 with congenital dysplasia of the hip: a case-control study" ppt
... (0.636) 95 (0.326) 11 (0.038) 46 5 (0.799) 117 (0.201) 0.78 Male 47 29 (0.617) 16 (0. 340 ) (0. 043 ) 74 (0.787) 20 (0.213) 0.91 All 622 342 (0.550) 2 34 (0.376) 46 (0.0 74) 918 (0.738) 326 (0.262) 0.50 ... (6%) 14 (0.667) (0.286) (0. 047 ) 34 (0.810) (0.190) 0. 74 subluxation 53 (16%) 33 (0.622) 18 (0. 340 ) (0.038) 84( 0.792) 22(0.208) 0.81 Dislocation 2 64 (78%) 167 (0.633) 87 (0.329) 10 (0.038) 42 1 (0.797) ... value 95% CI P value Patients with hip dislocation (n = 2 64) vs all controls (n = 622) 1 .41 0.023 1.05 to 1.89 0 .49 0. 044 0. 24 to 0.99 1 .40 0.0078 1.09 to 1.79 0.028 Patients with hip subluxation...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: "A statistical approach for detecting genomic aberrations in heterogeneous tumor samples from single nucleotide polymorphism genotyping data" pot
... Nature 2010, 46 4:999-1005 43 GAP [http://bioinfo-out.curie.fr/projects /snp_ gap/] 44 GenoCN [http://www.bios.unc.edu/~wsun/software/genoCN.htm] 45 OncoSNP [https://sites.google.com/site/oncosnp/] doi:10.1186/gb-2010-11-9-r92 ... (2000) SW 141 7 SW403 70 (66-71) 64 (60-65) Adbel-Rahman et al (2000) Adbel-Rahman et al (2000) SW480 58 (52-59) Adbel-Rahman et al (2000) SW620 48 (45 -49 ) Adbel-Rahman et al (2000) SW837 38 (38 -40 ) ... lines, the chromosome numbers predicted by OncoSNP (40 and 64 for SW837 and SW403 respectively) matched known karyotype information (SW837, range 38 -40 ; SW402, range 60 to 65) [36] Whilst it should...
Ngày tải lên: 09/08/2014, 22:23
báo cáo khoa học: "RRM1 single nucleotide polymorphism -37C®A correlates with progression-free survival in NSCLC patients after gemcitabine-based chemotherapy" potx
... by RRM1 SNPs RRM1 SNPs Response1 (n) PR SD C(-)37C 20 A(-)37C 14 A 245 5A 22 G 245 5G A 245 5G 13 G 246 4G A 246 4A 20 G 246 4A 13 PFS(weeks) P value3 PD A(-)37A P value2 24. 7 23.3 0.5 14 30.7 0. 043 26.9 ... 0 .42 8 ( 24/ 56) for C(-)37C, and 0.376 (21/56) for C(-)37A; for 245 5A®G, 0 .48 2 (27/56) for A 245 5A, 0.2 14 (12/56) for G 245 5G, and 0.3 04 (17/56) for A 245 5G; and for 246 4G®A, 0.5 54 (31/56) for A 246 4A, ... (-37C®A, P = 0.5 14; 245 5A®G, P = 0. 849 ; 246 4G®A, P = 0.191) For the polymorphism -37C®A, the median PFS was 30.7 weeks (95% CI, 24. 536.9) for the C(-)37A genotype, 24. 7 weeks (95% CI, 6. 842 .6) for A(-)37A,...
Ngày tải lên: 10/08/2014, 22:20
Báo cáo y học: "Association of the T allele of an intronic single nucleotide polymorphism in the colony stimulating factor 1 receptor with Crohn''''s disease: a case-control study" ppt
... Status vs CSF1R A2033T SNP: All Patients CDT Allele Absent T Allele Present Total CD+ Total 94 (87%) 14 (13%) 108 81 (73%) 30 (27%) 111 175 44 219 χ2 = 6. 74 (p < 0.01) O.R.:2 .49 (1.23 < O.R < 5.01) ... Hispanic Jewish Unknown Total 36 ( 84% ) (57%) 32 (91%) (87%) (100%) 12 (100%) 94 (16%) (43 %) (9%) (13%) (0%) (0%) 14 43 35 12 108 Acadian Non-Acadian Total 10 (53%) (47 %) 19 71 (77%) 21 (23%) 92 81 ... vs CSF1R A2003T SNP: Crohn's Patients T Allele Absent T Allele Present Total χ2 = 4. 81 (p < 0.05) O.R.:3. 04 (1.09 < O.R < 8 .47 ) Table 4: Crohn's Disease Status vs CSF1R A2033T SNP: Non-Acadian...
Ngày tải lên: 11/08/2014, 10:23
báo cáo khoa học: " Identification of Single Nucleotide Polymorphisms and analysis of Linkage Disequilibrium in sunflower elite inbred lines using the candidate gene approach" docx
... citation purposes) BMC Plant Biology 2008, 8:7 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 Ingvarsson PK: Nucleotide polymorphism and linkage disequilibrium within and among natural ... 0 .48 5 0.801 0.000 0 .48 5 0.199 0.256b 0.772 0.298 0. 649 0.3 74 -1.51 1.10 -1.02 -0.08 1.13 -0.50 2.93***c 1.36 0 .42 -1 .42 -0. 34 0.95 -0. 14 0.8266 -1.17 0.79 1.91 -0 .44 -0. 24 -0.73 1 .44 -1.19 1.39 -0.26 ... mechanisms against oxidative damage [46 ] (6) 744 513 231 40 (0) 561 351 210 15 (4) 569 219 350 (0) 739 732 7 (0) 5 04 5 04 Total 20 38 (217) 14, 348 9,506 4, 842 Average/locus 7.3 1.36 Frequency 1/...
Ngày tải lên: 12/08/2014, 05:20
Báo cáo y học: "Natural selection of protein structural and functional properties: a single nucleotide polymorphism perspect" potx
... time of divergence Mol Biol Evol 2006, 23:1-3 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 Volume 9, Issue 4, Article R69 Liu et al R69.16 Ashburner M, Ball CA, ... smell GO:0050896 0. 54 403 Response to stimulus GO:0007565 0 .48 43 Female pregnancy GO:0006298 0 .47 29 Mismatch repair GO:003 142 4 0 .46 GO:0007186 0 .43 22 Keratinization GO:0007131 0 .42 20 Meiotic recombination ... carboxy-terminal domain PF0 145 4 0 .45 24 MAGE family PF09723 0 .44 42 Putative regulatory protein (CxxC_CxxC_SSSS) PF02023 0 .44 39 SCAN domain PF00059 0 .43 58 Lectin C-type domain PF07859 0 .42 21 alpha/beta Hydrolase...
Ngày tải lên: 14/08/2014, 08:21
Báo cáo y học: "Whole genome sequencing of a single Bos taurus animal for single nucleotide polymorphism discovery" potx
... filters to a final set of 2 .44 million SNPs Of these SNPs, 1,6 94, 546 (69 .4% ) were homozygous and 749 ,091 (30.6%) were heterozygous The low proportion of heterozygous SNPs is mainly due to the relatively ... Identified SNPs and small indels All SNPs (Ensembl) Indel (Ensembl) Coding Non-synonymous Splice-site UTR 2 ,44 3,637 (18%) 22,070 (18%) 9,360 (15%) 148 ( 14% ) 8,1 14 (20%) 3,139 (16%) 40 (15%) 6,292 ... BovineSNP50 MAQ calls Concordant calls Homozygote reference 22,999 Homozygote variant 12, 043 8,9 74 ( 74. 51%) 8, 949 (99.72%) Heterozygote 13,683 5,882 (42 .98%) 4, 157 (70.67%) Comparison of the SNP...
Ngày tải lên: 14/08/2014, 21:21
BÁO CÁO " MỐI TƯƠNG QUAN GIỮA SNP (Single nucleotide polymorphisms) CỦA GEN CHH (crustacean hyperglycemic hormone) VÀ TÍNH TRẠNG TĂNG TRƯỞNG CỦA TÔM CÀNG XANH " potx
... 0,08* 0,77 ± 0,21 * * CH3 g. 240 2 1,71 -7 ,47 ± 0,32 ± 0,16 0,63 ± 0 ,41 * CH3 g. 240 7 3, 34 -7 ,47 ± 0,32 ± 0,16 0,63 ± 0 ,41 CH3 g. 240 9 3, 34 * -4, 39 ± -0,21 ± 0,10* -0, 54 ± 0,25 * * CH3 g.2561 2,01 ... A 0,98 g. 245 7 G Intron 0,01 0,05 0,999 A 0,99 g. 247 1 G Intron 0, 04 0 ,45 0,982 A 0,96 g.25 24 C Intron 0,83 0,33 0, 846 T 0,17 g.2561 G Intron 0,05 0,60 0,973 A 0,95 b SNPs 243 mẫu tôm (48 mẫu tôm ... 0,8 64 coef -5,30 -0 ,45 5,95 -1,28 0,05 BW (g) SE t P 3,65 -1 ,45 0,15 2,12 -0,21 0,83 1,61 3,69
Ngày tải lên: 19/03/2014, 11:20
Báo cáo y học: "Association of single-nucleotide polymorphisms in RHOB and TXNDC3 with knee osteoarthritis susceptibility: two case-control studies in East Asian populations and a meta-analysis" docx
... 10 (0.088) 216 (0.956) 10 (0. 044 ) Male 258 240 (0.930) 18 (0.070) 49 8 (0.965) 18 (0.035) OA, osteoarthritis; SNP, single nucleotide polymorphism (P = 0. 04; Table 4) No significant association ... OA All 46 9 398 (0. 849 ) 65 (0.139) (0.012) 861 (0.918) 77 (0.082) Female 323 2 74 (0. 848 ) 45 (0.139) (0.013) 593 (0.918) 53 (0.082) Male 146 1 24 (0. 849 ) 20 (0.137) (0.0 14) 268 (0.918) 24 (0.082) ... controls (n = 48 6) 0.70 0.18 0 .42 –1.18 0.71 0.19 0 .42 –1.18 Female patients (n = 323) versus female controls (n = 316) 1.02 0. 94 0. 54 1. 94 1.02 0. 94 0. 54 1.92 Male patients (n = 146 ) versus male...
Ngày tải lên: 09/08/2014, 10:23
BÀI BÁO CÁO TÌM HIỂU VỀ SNP (SINGLE NUCLEOTIDE POLYMORPHISMS)
... Thơ, tháng 10 năm 2012 SNP (SINGLE NUCLEOTIDE POLYMORPHISMS) I GIỚI THIỆU VỀ SNP - SNPs (đọc snip) viết tắt từ chữ Single Nucleotide Polymorphisms, có nghĩa dạng đa hình nucleotide đơn Marker ... The Scientist 13 Single Nucleotide Polymorphisms: From the Evolutionary Past 2001 Nature 14 Single Nucleotide Polymorphisms: To a Future of Genetic Medicine 2001 Nature 14 ... & Phát triển Nông thôn Trang 180-1 84 NCBI sở liệu đa hình đơn nucleotide (dbSNP) 13 Cơ sở liệu Nhật Bản đa hình đơn nucleotide (JSNP)News Network Genome dbSNP sở liệu - Từ Trung tâm Quốc gia...
Ngày tải lên: 18/03/2015, 09:12
báo cáo SNP (SINGLE NUCLEOTIDE POLYMORPHISMS)
... 180-1 84 NCBI sở liệu đa hình đơn nucleotide (dbSNP) Cơ sở liệu Nhật Bản đa hình đơn nucleotide (JSNP)News Network Genome dbSNP sở liệu - Từ Trung tâm Quốc gia Thông tin Công nghệ sinh học (NCBI) SNPs: ... for Gold in Genome Gulch 2002 The Scientist 13 .Single Nucleotide Polymorphisms: From the Evolutionary Past 2001 Nature 14. Single Nucleotide Polymorphisms: To a Future of Genetic Medicine ... (Kwor ctv 19 94) - SNP marker có tính ổn định cao mặt di truyền - Là sản phẩm PCR - Được tìm thấy với tần suất cao genome người - Độ đa dạng cao IV ỨNG DỤNG VÀ TRIỂN VỌNG CỦA SNPs SNPs đồ - Người...
Ngày tải lên: 09/05/2016, 16:53
Tài liệu Bắt đầu với CD CentOS 4.4 Single Server ppt
... CentOS 4. 4 MySQL 4. 1.20 Muốn nâng cấp lên MySQL 5, dùng lệnh sau: yum enablerepo=centosplus upgrade mysql* yum enablerepo=centosplus install mysql-server-5* Quản trị đơn giản Do CentOS 4. 4 Single ... kiến tôi, PHP MySQL Nhưng phần mềm tích hợp vào CentOS Plus Repository Mặc định, CentOS 4. 4 sử dụng PHP 4. 3.9 Muốn nâng cấp lên PHP 5, trước tiên phải đảm bảo máy bạn kết nối với Internet, sau ... giản để chắn thứ cài đặt phù hợp chạy mong đợi Kết luận CentOS phân phối Linux mạnh đáng tin cậy Single Server CD phiên gần đạt đến mức hoàn hảo cho tìm kiếm phân phối đơn giản đủ chức cho server...
Ngày tải lên: 12/12/2013, 00:15
single nucleotide polymorphisms - pui-yan kwok
... variation: 21 SNPs and indel formed 31 haplotypes in 5 ,49 1 bases of the APOE gene region in 144 chromosomes (12,13), which is a variant every 250 bases; 74 SNPs and indels formed 13 haplotypes in 24, 070 ... Sunderland, MA The International SNP Map Working Group (2001) A map of human genome sequence variation containing 1 .42 million single nucleotide polymorphisms Nature 40 9, 928–933 Kruglyak, L and ... SD18 GM2064A Positions of mutations from 5'-end of forward primerc (Positions within the MDR1 sequence) 91 (2398-11) C C C/A C 209 ( 248 1+ 24) G G/A G G/A 225 ( 248 1 +40 ) C C C C/T 258 ( 248 1+73) C...
Ngày tải lên: 08/04/2014, 12:52
Báo cáo khoa học: "Identification of single-nucleotide polymorphisms of the prion protein gene in sika deer (Cervus nippon laiouanus)" potx
... 25.15 84. 84 G C )%( ycneuqerf elellA 19. 04 90.95 C T )%( ycneuqerf elellA 30.3 79.69 G A )%( ycneuqerf elellA )72.72( ) 84. 84( 61 )42 .42 ( 33 622 nodoC G/G G/C C/C rebmun ... eht fo noitacifilpmA giF giF la te gnoeJ gnoeJ-nuyH 003 . 945 -035 , 24 ,5002 lohtaP teV esaesid gnitsaw cinorhC SE smailliW 643 1-9331 ,58 ,40 02 loriV neG J reed deliat-etihw ni esaesid gnitsaw cinorhc ... editoelcun-elgniS 8 04 seditoelcun ta reed akis citsemod esenapaJ dna esenihC ni deifitnedi neeb evah PNRP reed akis eht ni sPNS ehT )1 elbaT( ylevitcepser ,G dna C rof %25.15 dna 84. 84 erew msihpromylop...
Ngày tải lên: 07/08/2014, 23:22