... the adequacy of early EA in PP patients In our population, patients receiving IA therapy seem to be at risk of emergence of MDR strains and at high risk of inadequate EA In presence of this risk ... Emergence of antibiotic- resistant bacteria in cases of peritonitis after intraabdominal surgery affects the efficacy of empirical antimicrobial therapy Clin Infect Dis 1996, 23:486-494 Seguin P, ... methicillin-resistant staphylococcus or amoxicillin-resistant enterococcus carriage Adequacy of EA was assessed according to the regimen used and the number of antibiotics in the case of combination therapy...
... reason to think that ongoing infliximab therapy may be harmful, good data are lacking) Another finding of our study is that discontinuation of infliximab therapy seems justified, since we found ... within 12 weeks after discontinuation of infliximab infusions, 37 within 24 weeks, and 38 within 36 weeks By week 48, of the 42 patients had not needed retreatment and 41 were again receiving infliximab ... coordination MR: Monitoring and investigation of the patients, study coordination JS: Investigator, writing of the manuscript JB: Idea, writing of the manuscript, principal investigator, responsible...
... problem of increasing clinical significance Interferon (INF) therapy is the mainstay of HCV treatment HCV and HIV have been associated with the development of autoimmune markers and disease; INF therapy ... serum-ascites-albumin gradient of more than 12 which was non-infective Meloxicam and tenofovir were ceased because of worsening renal function and zidovudine was instituted in place Perindopril was ... Discussion The occurrence of SLE in the setting of HCV and INF administration is now well established [1-3] and represents an accentuation of the underlying cytokine changes described in SLE pathogenesis...
... a deteriorating clinical state In the present study, using two different approaches, delayed initiation of adequate antibiotictherapy was an independent predictor of impairment in inflammatory ... Delta-SOFA correlated significantly with delayed initiation of adequate antibiotictherapy (P < 0.0001; Figure 1) By multiple linear regression, the only independent predictor of an increase in SOFA ... delayed initiation of adequate antibiotictherapy (OR 1.14, 95% CI 1.06–1.24) SOFA score increased in 111 patients (median increase in score [range 1–6]) This increase was significantly greater in...
... duration ofantibiotic treatment, if interpreted in the clinical context including the underlying disease This can substantially improve to determine adequate duration ofantibiotictherapy with ... The frequency of multi-resistant pathogens in patients undergoing long-term antibiotictherapy is clearly increased [11] In this context, newly arising fungal infections in seven-day antibiotic ... length oftherapy Controls PCT-guided antibiotictherapyAntibiotic classes (%) P >0.05 Acylaminopenicillin + BLI 51.8 55.2 Acylaminopenicillin + nitroimidazole 19.6 15.5 Carbapenem 8.8 10.4 Aminobenzylpenicillin...
... duration ofantibiotictherapyin intensive care patients: a randomized prospective controlled trial Crit Care 2009, 13:R83 Hausfater P: Procalcitonin measurement in adult clinical practice [in French] ... French] Rev Med Interne 2007, 28:296-305 McLean A: Procalcitonin: seeking a niche Crit Care 2009, 13: 149 Christ-Crain M, Müller B: Procalcitonin and pneumonia: is it a useful marker? Curr Infect Dis ... Graf JD, Rohner P, Pugin J: Use of procalcitonin to shorten antibiotic treatment duration in septic patients A randomized trial Am J Respir Crit Care Med 2008, 177:498-505 Page of (page number not...
... explaining the link between availability of guidelines and prognosis This point was clearly emphasized in the studies assessing the effects of implementation of the guidelines of the surviving ... Decision-making process of AT In each center, the presence and number of empiric AT protocols were assessed The period of initiation of AT was defined by categorizing the week into day shifts and out -of- hours ... universally in the intensive care unit? Crit Care 2010, 14:205 doi:10.1186/cc9961 Cite this article as: Montravers et al.: Strategies of initiation and streamlining ofantibiotictherapyin 41 French intensive...
... measuring patients’ experiences of care rather than satisfaction per se Pre-testing of the questionnaire in 16 patients at NHNN undergoing relapse management resulted in minimal changes in wording ... friends were not closely involved in their care experiences Two domains (attitude of health care professionals; interpersonal care) were combined to form a single domain (interpersonal care) because ... information concerning the construct being measured, except for one item in the 11-item Coordination of Care scale These findings support the summing of items to generate subscale score Targeting (Table...
... No of infertile rats (%) (0) Total number of offspring* 184 Mean no of 11.50 ± 1.31 offspring/litter* (range) (8∼13) No of stillborn offspring (%) (0) No of live offspring (%) 184 (100) Mean offspring ... non-vaccinated control group The rats (n = 24) of the vaccinated group were injected intraperitoneally with 0.1 mL of physiological saline 10 containing × 10 CFU of the B abortus strain RB51 vaccine ... size and weight of offspring between RB51vaccinated and non-vaccinated rats in our studies indicated that RB51-vaccine elicited significant protection against infection in vaccinated rats when...
... specimen inoculated with P ostreatus, the combination of resin coating and edge painting did not lead to a significant improvement in the level of protection than the resin coating alone According ... period of a few years, but then, due to the leaching of the phenolic component decrease over time Analyzing the different plywood protections, the combination of resin coating and edge painting ... measuring 150 mm ´ 25 mm, 86 R Zanuttini et al were subjected to tension shear applied in a middle area of 25 ´ 25 mm with a testing machine having a maximum capacity of 50 kN and accuracy of ±...
... 1989), and more In this study, we intend to analyze the behaviour of species, Pinus pinaster, Pinus radiata and Pinus sylvestris, during germination, in relation to fire and to try to integrate the ... The seeds of P pinaster and P radiata came from harvest made in several sites in the provinces of A Coruña and Lugo (NW Spain), during the summer and autumn of 1990 The seeds of P sylvestris ... in the characteristics of a site may play an important role in determining the survival of the seedlings (Moreno and Oechel, 1992) To discover the adaptive advantages in the event of a fire of...
... (hearing loss alone in three, facial numbness and hearing loss in one, vocal cord paralysis and hearing loss in one, and temporary imbalance and/or vertigo in one) In 26 patients in whom hearing ... horner syndrome Ataxia and brain stem symptoms may also develop Involvement of the dural sinuses may mimic sinus thrombosis [11,12] In about 2-4% of cases, the first or leading symptoms are hypertension ... like symptoms) produced by catecholamines, norepinephrine, or dopamine excreted by the tumor Also, somatostatin, vasoactive intestinal polypeptide, calcitonin, and neuron-specific enolase may...
... tissues by assessing the gene expression profile of some of the Wnt signaling target genes:cyclin D, PCNA, survivin, b-catenin Methods Ninety albino female rats inbred strain (Cux1: HEL1) of matched ... gm) were included in the study Animals were inbred in the experimental animal unit, Faculty of Medicine, Cairo University Rats were maintained according to the standard guidelines of Institutional ... regulation of the transcription factor b-catenin, a key component of the Wnt signaling pathway [58] In the normal state, the binding of members of a family of soluble cysteine-rich glycoprotein ligands,...
... assessment using the following criteria [32-34]: (i) Insidious onset of pain in the Achilles tendon region that is aggravated by weightbearing activities and worse in the morning, and/or during the initial ... exercises To maintain blinding of participants, they will be advised that they will receive one of two types of 'shoe inserts' during the study Data collection and the interventions will be administered ... clinical trial comparing the effects of four weeks of physiotherapy treatment (n = 11) (total of 10 treatments: deep friction massage, ultrasound, ice and sensory motor training consisting of...
... schematically defined in the activation of EGFR-dependent intracellular signaling First, the binding of a receptor-specific ligand occurs in the extracellular portion of the EGFR or of one of the EGFR-related ... II study of cetuximab plus cisplatin/vinorelbine compared with cisplatin/vinorelbine alone as first-line therapyin EGFRexpressing advanced non-small-cell lung cancer Ann Oncol 2008 in press ... result primarily in G1 cell arrest in cancer cell lines with wild type EGFR, versus induction of apoptosis in cell lines with mutant EGFR [22] The combination of chemotherapy and TKI in some cases...
... vaccine does not reduce immunogenicity: pre-clinical assessment of the efficacy of a Listeria vaccine in the induction of immune responses against HIV Journal of Immune Based Therapies and Vaccines ... Percentage increase in CD44-b7 populations in response to overlapping Gag-peptide (B) Percentage increase in CD8-CD107a populations in response to overlapping Gag-peptide Lmdd-HIV-gag infiltration into ... with μCi per well of 3H-thymidine (PerkinElmer, Boston, MA) for 18 h prior to harvesting Thymidine incorporation was assessed using a b-scintillation counter (Beckman Coulter, Inc., Miami, FL)...
... attempting to determine the best mode and type of mental health treatment in these settings An increasing number of studies show the potential of group interventions for mental disorders in LAMICs ... effective in reducing depressive symptoms in women [52] In Iran, group CBT was superior to fluoxetine in treating depression and anxiety of infertile women [53] In addition, group based interventions ... self-examination therapyof Bowen et all [43] In ‘’self-examination therapy ’ subjects learn to take control of their problems and their lives by (1) determining what really matters to them, (2) investing...
... Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996, 17:1-12 Cai W: Efficacy and its influent factors of telbivudine or lamivudine treated ... Second, tenofovir is a new approved agents which hasn’t been introduced to lots of low-income economy countries like China So lamivudine and telbivudine are more widely used in treatment of CHB In this ... systematic review, we focus on the comparison of the efficay of lamivudine and telbivudine in the Figure Effect of telbivudine vs lamivudine at the end of one-year treatment on Therapeutic response...