2 4 dinitrophenol on ischemia induced blood brain barrier disruption pdf
báo cáo hóa học: " Anandamide inhibits Theiler’s virus induced VCAM-1 in brain endothelial cells and reduces leukocyte transmigration in a model of blood brain barrier by activation of CB1 receptors" pdf
Ngày tải lên :
19/06/2014, 22:20
... 12, 013 ± 0 ,48 9 13 ,22 3 ± 0,788 15,909 2, 327 15 909 ± 327 Ipsilateral 20 , 028 ± 1 ,25 7## 21 , 341 ± 0,958## 19,657 1, 120 19 657 ± 120 # contralateral 16,956 ± 0,913 17,151 ± 1,007 16, 320 0,796 16 320 ... cannabinoid WIN 5 ,21 2 -2 [23 ] In the TMEVIDD model we showed that WIN 5 ,21 2 -2 at the time of virus infection inhibited brain VCAM-1 expression and interfered with later disease onset [ 24 ] However, there ... endocannabinoid 2- AG protects the blood- brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines Neurobiol Dis 20 06, 22 :25 7 -26 4 15 Centonze D, Bari M,...
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Báo cáo y học: "Effect of magnesium sulfate administration on blood–brain barrier in a rat model of intraperitoneal sepsis: a randomized controlled experimental study" ppt
Ngày tải lên :
12/08/2014, 20:20
... 1. 044 4 ± 0.0001 1. 044 3 ± 0.00 02 0 . 24 S (8) 1.0 42 9 ± 0.0009a,b 1.0 42 4 ± 0.0012c,d 0 .44 C-Mg (8) 1. 044 4 ± 0.00 02 1. 044 4 ± 0.0001 0 .44 S-Mg (8) 1. 043 8 ± 0.0007 1. 043 9 ± 0.0004e 0 . 24 KW 18.831 24 . 7 24 ... gram-negative endotoxin on the blood brain barrier J Comp Neurol 1966, 127 :183-198 22 Jeppson B, Freund HR, Gimmon Z, James JH, von Meyenfeldt MF, Fischer JE: Blood brain barrier derangement in ... 0.0 046 6 ± 0.0002a,b 0.00 641 ± 0.0003c,d 0.13 C-Mg (8) 0.00135 ± 0.00 02 0.00 145 ± 0.0003 0 .44 S-Mg (8) 0.0 021 8 ± 0.0005 0.00199 ± 0.0007 0.57 KW 19. 720 23 .039 d.f 3 < 0.001 < 0.0001 P Abbreviations:...
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Thạc sĩ nghiên cứu phương pháp phân tích và xử lý axit 2,4 điclophenoxyaxetic (2,4 d)và 2,4 đinitrophenol (d
Ngày tải lên :
10/04/2015, 20:35
... 45 Bảng 3.6 Khảo sát thay đổi bước nhảy 2, 4- D Bước nhảy (V) 0,001 0,0 02 0,003 0,0 04 0,005 0,006 0,007 0,008 0,009 Ipic (nA) 22 6 25 2 25 4 27 6 23 5 22 6 24 2 28 7 28 0 DNP -Ep (V) 1,03 1, 02 1, 02 1, 02 ... 0,0 54 0 ,40 25 0 180 2, 00 2, 50 0,0 72 0,50 330 22 3 2, 25 2, 75 0,081 0,55 366 24 3 2, 50 3,00 0,09 0,60 41 0 26 4 3,00 3,75 0,108 0,75 48 6 325 3 ,25 0,117 523 Hình Sự phụ thuộc Ipic vào nồng độ 2, 4- D STT ... cho 2, 4- D Thời gian đuổi khí (s) 30 60 90 120 180 24 0 27 0 300 Ipic (nA) 344 3 42 341 340 339 340 330 325 -Ep (V) 1,03 1, 02 1, 02 1, 02 1, 02 1, 02 1, 02 1, 02 Nhận xét: Để đảm bảo đuổi hết oxi rút ngắn...
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the blood – brain barrier
Ngày tải lên :
11/04/2014, 10:34
... rats (28 3) 5.1 Immunophenotype of Perivascular Macrophages ED2 (Table 2; 26 6 ,27 7 ,28 4) is a universally accepted marker of perivascular cells along with CD45 (26 6 ,27 8 ,28 5), CD4 (28 6) and OX- 42 (26 6 ,27 7 ,27 8), ... to brain and muscle J Neuropath Exp Neurol 47 , 29 40 122 Shea, S M., and Raskova, J (1983) Vesicular diffusion and thermal forces Fed Proc 42 , 24 31 24 34 Morphology and Molecular Properties 27 ... basement membranes Lab Invest 44 , 560–565 21 4 Timpl, R (19 94) Proteoglycans of basement membranes EXS 70, 123 – 144 21 5 Hynes, R O (1986) Fibronectins Sci Am 25 4, 42 51 21 6 Timpl, R., Dziadek, M.,...
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báo cáo hóa học: " Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the blood-brain barrier is mediated by luminal microvessel IL-6 and GM-CSF" potx
Ngày tải lên :
19/06/2014, 22:20
... infection and dementia Science 20 00, 28 7:6 02- 6 04 22 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Hittinger G, Poggi C, Delbeke E, Profizi N, Lafeuillade A: Correlation between plasma levels of cytokines ... blood- brain barrier: Correlation between in vitro and in vivo models J Neurochem 19 92, 58:1790-1797 24 42 43 44 45 46 47 48 49 50 51 52 53 Waage A, Bakke O: Glucocorticoids suppress the production of ... (Fig 2B) from 72. 1 ± 1 .2 to 64 .2 ± 2. 8, 58.3 ± 2. 0, and 56 .4 ± 1 .4 × cm2 Abluminal treatment with IL-6 significantly decreased TEER from 72. 0 ± 2. 0 to 58.9 ± 2. 7 × cm2 at the concentration of...
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báo cáo hóa học: " Neuro-Inflammation, Blood-Brain Barrier, Seizures and Autism" pot
Ngày tải lên :
19/06/2014, 22:20
... and Erickson, M A.: The blood- brain barrier and immune function and dysfunction Neurobiol.Dis 20 10, 37 :26 - 32 44 Quan, N.: Immune-to -brain signaling: how important are the blood- brain barrierindependent ... Pharmacol Exp Ther 20 02, 303:1061-1066 51 Theoharides, T C and Konstantinidou, A.: Corticotropin-releasing hormone and the bloodbrain -barrier Front Biosci 20 07, 12: 1615-1 628 52 Rehni, A K., Singh, ... 6, 6 24 , 148 ; 6,689, 748 ; 6,9 84, 667, and EPO 1365777, which cover methods and compositions of mast cell blockers, including flavonoids, , US patents 7,906,153 and 12/ 861,1 52 (allowed on September, 22 ,...
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2 ĐỀ THI ÔN THI HỌC SINH GIỎI ANH 9 pdf
Ngày tải lên :
01/07/2014, 10:20
... (0,10 x = 0 ,40 ) C C A D II Grammar and vocabulary III : (0,30 x 36 = 10,80) D A B A C C A C B 10 C III Reading: 11 12 13 14 15 16 17 18 19 20 D B D A B B C C D D 21 22 23 24 25 26 27 28 29 30 B ... C at D on 23 The shape of……… snowflake is unique A no article B a C an D The 24 ………… simple precautions can prevent accidents at home and on the job A Few B a few C a little D A or B 25 I…………… ... A also B but C and D But also 28 This device shows a similarity ………….the one I have A of B from C to D on 29 The second draft was an improvement… the first A in B on C from D with 30 She wanted...
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Hình thái và chức năng của hàng rào máu não (blood brain barrier)
Ngày tải lên :
19/07/2014, 20:48
... tế bào ZO-1, ZO -2, cingulin protein thuộc tế bào chất khác [22 ] 20 4 .2. 1.Phân tử kết dính chức (Junctional Adhesion Molecules JAM) Các phân tử kết dính chức gồm: JAM-1, JAM -2 JAM-3 JAM-1 có ... nội mô (Bazzoni et al, 20 04) 17 Đóng Mở Màng tế bào Hình 4. 1: Hình thái thể liên kết khe (gap junction GJ) Vùng dính Màng tế bào Hình 4 .2: Hình thái protein vùng dính (Adherens Junctions) 18 Vùng ... rào máu não số tình trạng bệnh lý (Brown et al, 20 05) [1], [29 ] Ngoại bào Màng Tế bào chất Hình 4. 6: Sơ đồ cấu trúc phân tử Occludin[ 12] 22 4 .2. 3.Claudin Claudin có vị trí màng tế bào giống occludin...
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báo cáo khoa học: "Reactive oxygen species-mediated apoptosis contributes to chemosensitization effect of saikosaponins on cisplatin-induced cytotoxicity in cancer cells" pdf
Ngày tải lên :
10/08/2014, 10:20
... 20 09, 17(13) :45 42 - 7 Hsu YL, Kuo PL, Lin CC: The proliferative inhibition and apoptotic mechanism of Saikosaponin D in human non-small cell lung cancer A 549 cells Life sciences 20 04, 75(10): 123 1- 42 ... effect of ROS scavengers on cell death was correlated with significant reduction of O2- and H2O2 levels in cells (Figure 4C and 4D) To further confirm Figure ROS accumulation contributes to the synergistic ... or saikosaponin a improves hepatic antioxidant capacity and protects against CCl 4induced liver injury in rats Journal of medicinal food 20 08, 11 (2) :22 4- 9 25 Rabi T, Bishayee A: d-Limonene sensitizes...
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Báo cáo y học: "Inhibition of complement C5a prevents breakdown of the blood-brain barrier and pituitary dysfunction in experimental sepsis" ppt
Ngày tải lên :
13/08/2014, 15:21
... Younkin EM, Kunkel RG, Ding J, Erickson R, Curnutte JT, Page of (page number not for citation purposes) 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 Ward PA: Role of C5a in multiorgan ... hormones involved in the control of inflammation Faseb J 20 03, 17 :22 66 -22 68 72 Lewis BM, Francis K, Monk P, Scanlon MF, Ham J: Complement C5a inhibits the secretion of macrophage migration inhibitory ... Neurosci Lett 1996, 21 3:37 -40 44 Hess DC, Bhutwala T, Sheppard JC, Zhao W, Smith J: ICAM-1 expression on human brain microvascular endothelial cells Neurosci Lett 19 94, 168 :20 1 -20 4 45 Rieckmann P,...
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Application of biologically active micelles in drug delivery across the blood brain barrier
Ngày tải lên :
11/09/2015, 09:10
... 22 3 .2. 2.1 Drug lipophilicity modification 22 3 .2. 2 .2 Other modifications .23 3 .2. 3 Physiologically-based strategy .23 3 .2. 3.1 Endogenous BBB transporters 24 3 .2. 3 .2 ... nanoparticles in brain drug delivery 29 4 .2. 1 PBCA nanoparticles .29 4 .2. 2 PEGylated PLA/PLGA nanoparticles 32 4 .2. 2.1 Nanoparticle preparation 32 4 .2. 2 .2 PEGylated nanoparticles conformations ... of the blood brain barrier (BBB) 10 2. 1 Structure of the BBB 12 2.1.1 Endothelial cells 12 2.1 .2 Other cell types 13 2. 1 .2. 1 Astrocytes 14 2. 1 .2. 2 Pericytes...
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Nanoparticles of biodegradable polymers for delivery of therapeutic agents and diagnostic sensitizers to cross the blood brain barrier (BBB) for chemotherapy and MRI of the brain
Ngày tải lên :
26/11/2015, 22:48
... TECHNOLOGY 21 2. 3.1 Introduction of Nanoparticles 21 2. 3 .2 Fabrication techniques of Nanoparticles 22 2. 3 .2. 1 Dispersion of performed polymers 22 ii 2. 3 .2. 2 Polymerization methods 24 2. 4 BIODEGRADABLE ... Fabrication of nanoparticles 41 3 .2. 2 .2 Encapsulation efficiency of Gd-DTPA 42 3 .2. 2.3 In vitro release of gadolinium 42 3 .2. 2 .4 In vitro and in vivo MRI 42 CHARPTER FOUR: RESULTS AND DISCUSSION 44 4. 1 ... osmotic blood brain barrier disruption [40 -44 ] and biochemical blood brain barrier disruption [45 -47 ] Alternative routes to CNS drug delivery include intraventricular/intrathecal route [48 ], and...
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Tài liệu Báo cáo Y học: Studies on the nonmevalonate pathway of terpene biosynthesis The role of 2C-methyl-D -erythritol 2,4-cyclodiphosphate in plants docx
Ngày tải lên :
22/02/2014, 07:20
... 16.00 16. 04 16. 52 42 . 3 17, 170 42 . 5, 3.5 42 . 5 18, 180 42 . 5, 3.5 42 . 2 19, 190 40 .7 42 . 0 20 , 20 0 13 43 .3 42 . 2 42 . 2 42 . 2 42 . 0 a Referenced to external TMS; bfrom the experiment with [2, 20 -13C2]2C-methyl-D ... 100 11, 110 12, 120 13, 130 14, 140 15, 150 16, 160 17, 170 18, 180 19, 190 20 , 20 0 131 .23 123 .97 26 .77 39. 72 1 34. 93 1 24 .22 26 . 74 39. 72 135.33 1 24 .41 26 .68 40 .49 139.51 120 .22 123 .35 25 .69 17.68 ... [2- 14C]cMEPP [1-3H]MEP Sp radioact (mCi·mmol21) Conc (mM ) Sp radioact (mCi·mmol21) 14 Experiment Conc (mM ) C : 3H (%a) [1-3H]cMEPP produced (nmol) A B C D 0. 040 0. 040 0. 040 0. 040 20 20 20 20 ...
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báo cáo hóa học: " Effects of the cyclooxygenase-2 inhibitor nimesulide on cerebral infarction and neurological deficits induced by permanent middle cerebral artery occlusion in the rat" potx
Ngày tải lên :
19/06/2014, 22:20
... http://www.jneuroinflammation.com/content /2/ 1/3 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 Fisher M: Stroke Therapy 2nd edition Butterworth Heineman; 20 01 Kassem-Moussa H, Graffagnino C: Nonocclusion and spontaneous ... Vehicle Nimesulide 0.5 (2 5) (2 5) (3–5) (2 5) 3.5 (2 5) (1–3) ** (1 4) ** (1–5) * (2 5) (2 5) 44 ± 17 40 ± 21 50 ± 11 47 ± 16 52 ± 23 81 ± 18 ** 85 ± 22 ** 73 ± 13 * 60 ± 15 59 ± 14 Values represent ... 7) Nimesulide 12 mg/kg, single dose (n = 8) 128 ± 21 (3–5) (2 4) (1–5) * (1 4) ** 49 ± 18 64 ± 13 89 ± 20 ** 84 ± 14 ** (3–5) 3.5 (2 5) 43 ± 21 52 ± 19 Values show the median and range (neurological...
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báo cáo hóa học: " Effects of betaine on lipopolysaccharide-induced memory impairment in mice and the involvement of GABA transporter 2" doc
Ngày tải lên :
19/06/2014, 22:20
... Res 20 04, 77 :4 02- 40 9 - 20 - 12 Takanaga H, Ohtsuki S, Hosoya K, Terasaki T: GAT2/BGT-1 as a system responsible for the transport of γ-aminobutyric acid at the mouse bloodbrain barrier J Cereb Blood ... transcription and beyond Pflugers Arch 20 04, 44 9 :22 7 -23 4 Go EK, Jung KJ, Kim JM, Lim H, Lim HK, Yu BP, Chung HY: Betaine modulates age-related NF-κB by thiol-enhancing action Biol Pharm Bull κ 20 07, ... injection Figure Figure (A) ** 20 * 10 30 ** ** 20 10 0 24 Time after administration (hr) iNOS / ß-actin 50 * 40 (D) Sham control (n=5) LPS (n=5) ** 30 24 Time after administration (hr) 20 10...
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Báo cáo hóa học: " The Effect of Single, Binary and Ternary Anions of Chloride, Carbonate and Phosphate on the Release of 2,4-Dichlorophenoxyacetate Intercalated into the Zn–Al-layered Double Hydroxide Nanohybrid" pot
Ngày tải lên :
22/06/2014, 00:20
... with 2, 4- D 34 62 %transmission/arbitrary units 10 94 1736 147 8 126 4 123 4 8 04 42 8 ZANDI Controlled Release of 2, 4- D into Aqueous Media 343 8 16 14 868 148 6 1068 768 128 6 620 The release of 2, 4- D from ... 0.000 027 49 8 CO3 99 3, 828 0.3 72 0.966 0. 529 1.000 0.000033 107 PO4 93 701 0. 42 7 0.511 0.616 0.997 0.000083 45 Cl-CO3 80 1, 744 0. 623 0.697 0.797 0.990 0.000 0 24 167 Cl-PO4 88 840 0.378 0 .44 5 0.567 ... Appl Clay Sci 40 (1 4) , 99–107 (20 08) Q.Z Yang, J Yang, C.K Zhang, Int J Pharm 326 , 148 –1 52 (20 06) M.Z Hussein, Z Zainal, A.H Yahaya, D.W.V Foo, J Control Release 82( 2–3), 41 7– 42 7 (20 02) M.Z Hussein,...
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4 tiet on tap cuoi hoc ky 2
Ngày tải lên :
07/07/2014, 21:00
... lastnight II Consolidation and homework 2 Date of preparing Date of teaching 10a1 10a6 10a5 10a7 Period: REVIEW FOR THE SECOND TERM Lesson I Aims To guilde students know ... going to or will + one of these verbs: be (2) , come, get, like (2) , play, meet, pass, travel, walk, buy I with Tim in the park tonight He asked to be there at 7.00 Don't worry about your ... adj/adv + EST Long adj/ adv: the + MOST + adj/adv 6 II Consolidation and homework Date of preparing Date of teaching 10a1 10a6 10a5 10a7 Period: REVIEW FOR THE SECOND TERM Lesson I Aims To guilde...
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Ôn Tập 11 CB (Unit 1 & 2 - 4 Tests)
Ngày tải lên :
12/07/2014, 18:00
... A 21 B 31 A 41 A A 12 B 22 D 32 C 42 B A 13 C 23 B 33 D 43 A D 14 A 24 C 34 A 44 B C 15 D 25 C 35 C 45 A D 16 B 26 D 36 C 46 D D 17 C 27 B 37 C 47 C C 18.D 28 B 38 B 48 D A 19 B 29 B 39 A 49 ... 10 B 20 A 30 C 40 C 50 C PRACTICE TEST A 11 A 21 C 31 A 41 A B 12 B 22 A 32 B 42 B B 13 D 23 A 33 B 43 C D 14 B 24 A 34 B 44 C A 15 A 25 A 35 D 45 A C 16 D 26 A 36 B 46 B A 17 C 27 C 37 A 47 D ... B 28 A 38 A 48 C D 19 A 29 B 39 C 49 B 10 A 20 D 30 B 40 B 50 A UNIT PRACTICE TEST 1 C 11.D 21 D 31 C 41 C B 12 A 22 C 32 C 42 B B 13 B 23 C 33 A 43 C C 14 C 24 C 34 B 44 B A 15 D 25 B 35 D 45 ...
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Giáo án lớp 2 môn Tập Làm Văn: TIẾT 4: Cảm ơn - xin lỗi ppsx
Ngày tải lên :
05/08/2014, 13:21
... bạn * Bài 2: Viết lời xin lỗi em - HS đọc y/c đề trường hợp sau: - HS làm việc theo nhóm - GV giúp HS hiểu yêu cầu - Đại diện nhóm trình bày + Tớ xin lỗi cậu… - HS nhận xét bổ sung + Con xin lỗi ... viết 3, câu nói - HS trình bày kq, nx, bs ND tranh - GV quan sát, sửa lỗi, nhắc nhở - GV chấm từ 4- bài, nhận xét, chữa Củng cố dặn dò: ( 3') - Nhận xét học - VN tập nói lời cảm ơn xin lỗi người...
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