... Marisol Sanjines (Head of Outreach) TheHuman Development Report Office (HDRO): TheHuman Development Report is the product of a collective effort Members ofthe National Human Development Report ... is the fruit of a collaborative effort by a team of eminent consultants and advisers and theHuman Development Report team Kevin Watkins, Director oftheHuman Development Report Office, led the ... the consequences In the long-run, the problems ofthe poor will arrive at the doorstep ofthe wealthy, as the climate crisis gives way to despair, anger and collective security threats None of...
... regions ofthehuman ANT2 promoter are shown in grey The two Sp1 AB box activation elements are shown as open symbols (B) DNA sequence ofthe silencer region (nucleotides )413/)235) ofthehuman ... transfection efficiency The values ofthe activities are set relative to the activity ofthe clone carrying wt Site-2 and Site-3 elements The results represent the mean value ± S.E of five independent ... Identification ofthe Site-2 and Site-3 binding protein as a member ofthe NF1 family of transcription factors (A) Binding of purified, recombinant NF1 to the Site-2 and Site-3 elements was monitored by the...
... structure ofhuman SUMO-2 is more similar to that of yeast SMT3 than to the NMR structure of SUMO-1 The difference between SUMO-2 Table Refinement procedures ofthe SUMO-2 crystals Description of steps ... is particularly evident in the regions of 28–43 and 71–83, that correspond to the strand b2, the N terminus ofthe helix a1, the helix a2, and the connecting loop to the strand b5 (Fig 3A,D) Such ... with the Gly93 of another The crystal structures of diubiquitin and tetraubiquitin showed some alternatives ofthe quaternary conformations of ubiquitin polymer for efficient recognition by the...
... and characterization ofhuman L-RAP gene promoter Figure shows the nucleotide sequence ofthe 5¢-flanking region ofthehuman L-RAP gene The transcriptional initiation site ofthe gene was determined ... activity These results further confirm the roles of transcription factors in the expression ofthe L-RAP gene Discussion L-RAP ⁄ ERAP2 is a newly identified ER aminopeptidase and the third member ofthe ... Differential usage of exon 15 causes the generation of two truncated forms ofthe transcripts These results indicate that at least three mRNAs encoding either the full length or truncated form of L-RAP...
... sequencing and the PCR/RFLP method As the ALI5 mutation is located in the region corresponding to thehuman exon 27, this exon was also screened by SSCP Results Analyses of microsatellites In the present ... ofthe markers did show a significant allele distribution between the patient and control group Conclusion In conclusion, our analysis ofthehuman PLCγ-2 gene did not reveal an association of ... with a phenotype comparable to WG Therefore, human PLCγ-2 is a good candidate gene for seeking predisposing genetic factors for WG Thehuman gene is a member ofthe PLC family comprising 12 closely...
... that the value of Ln P(D) increased consistently with increasing K However, the secondorder rate of change ofthe likelihood function (ΔK) showed a clear peak at K = 8, reflecting the existence of ... analysis runs For the sake of clarity, we named the seven sub-populations identified in the K = analysis based on both the geographical location and hosts ofthe viruses assigned with the sub-populations ... genetic differences between the 34 minor sub-populations (40.96% ofthe diversity) and seven major subpopulations (30.65% ofthe diversity; Table 1) To further test whether the 34 identified minor...
... and the extracted viral RNA was used for RT-PCR The Mon340 and Mon348 primers were used for the amplification ofthe ORF1a region, and the Mon269 and Mon270 primers for the amplification of ORF2 ... in the Neighbor program In 89 ofthe 120 AstV specimens isolated from 2004 to 2005, the nucleotide sequence ofthe partial ORF1a amplicon amplified The phylogenetic analysis results showed the ... case of ORF2, the 88 nucleotide sequences were analyzed and the phylogenetic tree was constructed The HAstV-1 prototype, the Oxford strain, and the Dresden strain clustered, unlike in the case of...
... Combination ofthe interaction data creates a consolidated set of 31,609 interactions between 7,748 human proteins On the basis of this initial set of interactions, we estimate the scale ofthehuman ... × 10-5) shows the clustering in thehuman protein interaction network is considerably above that expected at random, in spite ofthe incompleteness ofthe network The 'degree' ofthe network is ... study the features ofthe network, we visualized the complete network of protein interactions in Figure On superimposing a histogram ofthe density of interactions on the plot, we see that there...
... The story of material origins is not the story the text is telling here The authors, under the guidance ofthe Holy Spirit, have told the part ofthe story that is most significant to them (the ... sider the scenario of Moses sitting down with the elders ofthe people on the eve ofthe tabernacle dedication at the foot of Sinai He is trying to help the Israelites understand the gravity of ... claim The creatures ofthe sea were in a liminal zone in the ancient Near East After all, the sea was the very embodiment of non-order Therefore, there would be questions about the functions of the...
... list of flanking sequences that were used for designing the SNP assays To ensure that the location ofthe SNPs map to the genome as annotated, the flanking sequences were mapped back to thehuman ... buffer with 1.5mM MgCl2, 1.5µl of 5µM ofthe forward primer, 1.5µl of 5µM ofthe reverse primer, 1.5µl of 100% DMSO (Sigma-Aldrich, USA), 100ng of genomic DNA and 0.2µl of High Fidelity Taq DNA polymerase ... calculating the probability ofthe observed data for all possible values of D' The upper (CU) and lower (CL) bounds represent the 5% tails ofthe overall probability For blocks that consist of or more...
... (Applied Biosystems) The 46 sequencing reaction mixture consisted of 4.2 μl of autoclaved water, about 300 ng ofthe plasmid DNA, 0.8 μl of 2.5 μM primer and μl of BigDye The PCR reaction sequencing ... times with 10 column volumes of PBS each time With the addition of 40 units of Thromin (Sigma) per ml of resin, the proteins were released from GST after four hours of incubation at room temperature; ... samples were then placed in the 50 reaction cell, and ligands were loaded into the 300 μl injection syringe Normally, the sample concentration in a syringe is 20-fold ofthe one in the cell Titrations...
... almost all ofthe OLP epithelium The count was performed by two investigators without knowledge of whether the samples were control or experimental The total number of basal and suprabasal epithelial ... PermountTM Negative controls consisted of omission ofthe primary or the secondary antibody or primary incubation in the presence of non-immunized rabbit serum instead ofthe primary antibody Cell quantification ... of hMSH2 Therefore, the reduced expression of hMSH2 protein could make the epithelium of OLP more susceptible to DNA mutation, making it prone to oral squamous cell carcinoma development Further...
... Cookies TheTheTheTheThe sum of 25 and is 30 difference of 25 and is 20 product of 25 and is 125 quotient after division of 25 and is remainder after division of 25 and is As with all other programming ... changing the values ofthe variables to match each other, and gasp in awe as the output changes In case the equals() method doesn't appeal to you, JSP offers you a choice in the form ofthe compareTo() ... And if the two strings are identical, the comparison will return Incidentally, the comparison is based on both the first character ofthe string, and the number of characters in Flavour OfThe Month...
... referring to parts ofthehuman body The position of proverbs referring to part ofthehuman body Parts ofthehuman body 21 21 21 The classification of parts ofthehuman body according ... diversified (multiple form) The classification of parts ofthehuman body according to the position In the system ofthe proverbs, the system of words referring to parts ofthehuman body is divided ... functions: the function of comprehension, the aesthetic function, the function of education, the words about parts ofhuman body are used to form the meaning of proverbs, therefore, they become...
... earth The hand of a child - The hand of a lock The heart of a man - The heart of a matter 37 The tongue of a man - The tongue of a shoe The tooth of a person - The tooth of a comb The head of a ... hands of a farm 13 The heel of a person - The heel ofthe hand 14 One's leg - The leg of a trip 15 One's brain - The brains of a family 16 The bosom of a person - The bosom ofthe church 17 The ... part There are various types of similarity: - The similarity of shape E.g: The teeth of a saw, the head of a cabbage - The similarity of position E.g: The tail of procession - The similarity of...
... geothermal energy So far, even the high potential of RE resources, their contribution in electricity production in Vietnam is still negligible The Government of VN recognized important role of ... 4000 MW Geothermal energy and other types (tide, ocean waves ) Potential of geothermal energy resources: 200- 340 MW The renewable energy type such as tide and sea waves are in the stage of potential ... has been prepared by Institute of Energy Institute of Energy Main Contents of RE Master Plan and Some Preliminary results 2.1 Organization of RE MP Present status of RE development 1.1 Existing...
... product of PRPP from the crystallization solution ing 81 compounds of substrates, products and regulators of other enzymes in thehuman nucleotide metabolism (Table S1) The library can then be ... interacts with both O6 and N7 (Fig 1C) The 2¢OH ofthe ribose is hydrogen bonded to the main chain and the side chain of Asp142 (Fig 1C) Both hydroxyl groups ofthe ribose are involved in coordinating ... ligands for enzymes in thehuman nucleotide metabolism These were selected as substrates, intermediates and products of other enzymes in thehuman nucleotide metabolism The library was screened...
... monomer of poly(dT), showing that the changes were mainly due to the binding ofthe first DNA, while the binding ofthe second DNA had less influence (Fig 5A) To ensure that the estimation ofthe protein:poly(dT) ... in these eukaryotic and archaeal proteins (Fig 1A) Like the case of bacterial RecA, the L1 and L2 loops ofthe eukaryotic Rad51 proteins face A Roles ofthe HsRad51 L1 and L2 loops inside of their ... precision of 3% The changes occurring upon the addition ofthe element are noted in parentheses ND, not determined Y Matsuo et al ciation, like the case of Tyr188 of Xenopus laevis Rad51 [28] These...
... type of KLK11, isoform 2, despite the presence of exon 1c The secretory pathways of KLK11 isoforms appeared to differ, although both isoforms were secreted from cells Hence, the promoter use ofthe ... the isoform of translation products through the determination ofthe first exon in KLK11 mRNA (summarized in Fig 2A) Detection ofthe first exon in each KLK11 mRNA reflects the promoter use in the ... a part of isoform mRNA The third exon, exon 1c, extended from +1379 to +1454 The noncoding exons of exons 1a and 1c contributed to the 5¢ nontranslated region of isoform mRNA in which the common...
... functionality and phylogeny However, the nature ofthe connections between these factors needs to be understood at the level ofthe protein domain The global properties ofthe HTFN topology are partially ... graph of N ¼ 230 interacting human TFs was obtained (Fig 1) This can be understood as the architecture ofthe regulatory backbone It provides a topological view ofthe interaction patterns among the ... features of each group self-interaction is understood as the interaction between proteins ofthe same type, i.e homo-oligomerization, regardless ofthe number of monomers involved To evaluate their...