2 intrauterine exposure and breast cancer risk

... and risk of (a) early breast cancer and (b) late breast cancer Table Summary of the results on the relationship between breast cancer and reproductive factors according to age at diagnosis Risk ... for breast cancer Breast cancer risk increased with increasing age at FFTP by 5% (95% CI: 5-6%) per year for breast cancer diagnosed early or before menopause and by 3% (95% CI: 2-4%) for cancers ... of 21 studies on the relationship between breast cancer and age at menarche Breast cancer risk decreased with increasing age at menarche Breast cancer risk decreased by about 9% (95% CI: 7-11%)...

Ngày tải lên: 05/03/2014, 17:20

... the effect of the breast size on the relationship between mammographic density and breast cancer risk They found that the association between breast density and breast cancer risk was weaker in ... K, Pruthi S, Brandt KR, Pankratz VS: Mammographic density, breast cancer risk and risk prediction Breast Cancer Res 2007, 9:217 McCormack VA, dos Santos Silva I: Breast density and parenchymal ... Ministry of Health, Welfare and Sports (VWS); and ZONMw We thank Statistics Netherlands (CBS) and Netherlands Cancer Registry (NKR) for data on cancer and death, and screening organization ‘Bevolkingsonderzoek...

Ngày tải lên: 22/03/2014, 17:20

... first birth, parity and risk of breast cancer in a Swedish population, Br J Cancer 1980;42:651-658 Pathak DR, Speizer FE, Willett WC, Rosner B, Lipnick RJ Parity and breast cancer risk: Possible effect ... reproductive factors and breast cancer, Am J Epidemiol 1987;126:831-841 47 Boyle P, Leake RE Progress in understanding breast cancer: Epidemiologic and biologic interactions, Breast Cancer Res Treat ... between risk factors for breast cancer and hormonal status, Int J Epidemiol 1986;15:469-476 Talamini R, La Vecchia C, Franceschi S, et d Reproductive and hormonal factors and breast cancer in...

Ngày tải lên: 28/03/2014, 16:20

... associations between PAH exposure and breast cancer risk [4,66] Petralia et al [66] found elevated breast cancer risk among premenopausal women exposed to PAHs and benzene Risk was found to be increased ... fourteen had an excess breast cancer risk before age fifty [50] Band et al [21] found in pre- and postmenopausal cases (combined) elevated breast cancer risk in fruit and other vegetable farming ... opportunity to evaluate these chemicals and the risk of breast cancer in occupationally exposed women [15] Research regarding occupational exposures and breast cancer risk has generally been a neglected...

Ngày tải lên: 06/03/2014, 02:21

... for breast cancer risk assessment and stratification among Chinese women J Natl Cancer Inst 2010, 102:972-981 18 Gail MH: Personalized estimates of breast cancer risk in clinical practice and ... assess the breast cancer risk model (1) SNPs screening Following a two-stage strategy, associations between SNPs and risk of breast cancer were estimated by computing odds ratios (ORs) and their ... 0-2 risk alleles as and more than risk alleles as 1) and found no heterogeneity between subgroups (Additional file 3) Discussion In our study involving 1792 breast cancer cases and 1867 cancer- free...

Ngày tải lên: 21/06/2014, 19:20

... association between obesity and post-menopausal breast cancer risk, one might expect that total energy consumption and other dietary factors may influence breast cancer risk, possibly in a manner ... suggestion of a reduction in breast cancer risk in the intervention group, as well as apparent interactions of the E-alone hazard ratio with several other breast cancer risk factors [14] The DM trial ... CaD trial did not yield evidence of an effect on breast cancer risk [16] Page of We studied 4,988 SNPs in relation to breast cancer incidence and clinical trials intervention effects during the...

Ngày tải lên: 11/08/2014, 12:21

... (Thr241Met) polymorphism and lung cancer risk Cancer Epidemiol Biomarkers Prev 2001; 10: 911-2 26 Chen S, Tang D, Xue K, et al DNA repair gene XRCC1 and XPD polymorphisms and risk of lung cancer in a Chinese ... polymorphism and risk of primary lung cancer Carcinogenesis 2003; 24: 1677-81 57 Cui Y, Morgenstern H, Greenland S, et al Polymorphism of Xeroderma Pigmentosum group G and the risk of lung cancer and ... polymorphism and risk of lung cancer in a Chinese population Cancer Genet Cytogenet 2006; 164: 66-70 17 Matullo G., Dunning AM, Guarrera S, et al DNA repair polymorphisms and cancer risk in non-smokers...

Ngày tải lên: 31/10/2012, 14:59

... increasing cancer risk due to N-nitrosamine and cured meat intake is considered insufficient for GC and possible for OC[8] A previous review of dietary nitrates, nitrites and NOC and risk of nasopharynx, ... review and evaluate the available epidemiological evidence about the association between dietary exposure to preformed nitrosamine and related food intake and gastric and oesophageal cancer risk ... evaluated Exposure definition and classification Since information about gastric cancer and NOC and their precursors was heterogeneous, sources of exposure were classified into two groups: nitrosamines and...

Ngày tải lên: 06/03/2014, 02:21

... OCCUPATIONS AND BREAST CANCER RISK A few reports have addressed women autoworkers and risk of breast cancer A cohort study published in 1994 found no association between female breast cancer and automotive ... regarding breast cancer risk in agriculture, health care, and the automotive industry FARMING OCCUPATIONS AND BREAST CANCER RISK While some studies of farming populations have shown an elevated risk ... better understand the significance of timing of exposure in terms of cancer risk KEYWORDS: breast cancer; occupation; environment; farming; Canada INTRODUCTION The lifetime risk for breast cancer among...

Ngày tải lên: 06/03/2014, 02:21

... mobile phone use and brain cancer risk Germany Dr Joachim Schüz Head, Department of Biostatistics and Epidemiology Institute of Cancer Epidemiology Danish Cancer Society Strandboulevarden 49 ... use and brain cancer risk Communication of results to media and interested parties This press release was prepared jointly by IARC, UICC and CREAL It was decided by the Interphone Study Group, and ... reports on mobile phone use and brain cancer risk New Zealand Professor Alistair Woodward School of Population Health University of Auckland Private Bag 92019 Auckland 1142 Tel +64 93 73 75 99...

Ngày tải lên: 06/03/2014, 02:21

... Life and Breast Cancer 519 Relationships between emotional control, adjustment to cancer and depression and anxiety in breast cancer patients Psychology Medicine, 21, 51–57 Watson, M., Haviland, ... support, and age in survival from breast cancer Journal of Psychosomatic Research, 27, 77–83 Grandstaff, N.W (1976) The impact of breast cancer on the family In: J.M Vaeth (Ed.), Breast cancer: ... for women with breast cancer Quality of Life and Breast Cancer 509 Methods Participants The sample consisted of 63 women diagnosed with stage II breast cancer who were currently cancer free Patients...

Ngày tải lên: 22/03/2014, 17:20

... Reproductive factors and breast cancer risk among older women Breast Cancer Res Treat 2007, 102:365-374 Collaborative group on hormonal factors in breast cancer: Breast cancer and breast feeding: ... decrease breast cancer risk are ever having breast fed and longer durations of breast feeding [3,29-31] Some studies showing a longer duration of breast feeding decreases breast cancer risk [30,32] ... Turkish women with breast feeding and decreased risk of breast cancer Our data in univariate analysis also suggested that the association between decreased risk of breast cancer and breastfeeding...

Ngày tải lên: 09/08/2014, 04:21

... Second cancer risk reduction Following RT for HL, breast and lung cancer account for the greatest burden of excess risk [1] The estimated ERRs for radiation-induced breast cancer and lung cancer ... experience increased risks of secondary cancer (SC), in particular breast and lung cancer, and cardiac disease attributable in part to radiotherapy (RT) [16] Most published estimates of SC risks after ... http://www.ro-journal.com/content/2/1/13 Table 3: Estimated excess relative risk (ERR*) of secondary breast and lung cancer 20 years after radiation exposure Female Breast Female Lung Age at RT (yrs) Male Lung Age at...

Ngày tải lên: 09/08/2014, 10:21

... between the CYP1A1MspI and exon7 polymorphisms and lung cancer risk We evaluated this risk with regard to combinations of variants (i.e., type B and type C for MspI and Ile/Val and Val/Val for exon ... MspI and exon7 gene polymorphisms and lung cancer risk, and performed the subgroup analysis stratified by ethnicity, histological types of lung caner, gender and smoking status of case and control ... plot (random-effects model) of lung cancer risk associated with CYP1A1 exon7 genotype for the combined Ile/Val and Val/Val vs Ile/Ile Figure Forest plot (random-effects model) of lung cancer risk...

Ngày tải lên: 10/08/2014, 10:21

... BA: Polygenic susceptibility to breast cancer and implications for prevention Nat Genet 2002, 31:33-36 Walsh T, King MC: Ten genes for inherited breast cancer Cancer Cell 2007, 11:103-105 Mäkiniemi ... any TOPBP1 gene variants can contribute to hereditary breast cancer risk Abbreviations SNP: single nucleotide polymorphism; BRCT: breast cancer carboxyterminal; PCR: polymerase chain reaction; ... associated with hereditary susceptibility to breast and ovarian cancer Eur J Cancer 2006, 42:2647-2652 Antoniou AC, Easton DF: Polygenic inheritance of breast cancer: Implications for design of association...

Ngày tải lên: 11/08/2014, 07:21

... brain tumor, and a male and a female paternal second degree cousin had breast cancer However, her family history was negative for colon cancer, endometrial or ovarian cancers, thyroid cancer, or ... that leads to endocrine gland tumors and/ or hyperfunctioning commonly involving the pituitary, adrenal, and thyroid glands, as well as myxomas (skin, heart, and breast) and lentiginosis in select ... including sebaceous gland carcinoma, papillary thyroid carcinoma, and breast cancer Her mother who died at age 73 and maternal aunt who died at age 67 with a diagnosis of breast at around age...

Ngày tải lên: 11/08/2014, 17:21

... progesterone-positive, and approximately one in five breast cancers is human epidermal growth factor receptor 2/erb-B2 (HER2)positive breast cancers Hormone receptor-positive and HER2-positive breast cancers ... 2010) Breast cancer is a heterogeneous entity with distinct subsets characterised by differences in tumor biology and response to therapy The majority of breast cancers are estrogen receptor -and/ or ... Fcy/5FC and CodA/5-FC in co-culture experiments 83 11 Figure 14 HSVtk/GCV and CD/5-FC for breast cancer therapy mediated by iPSC-NSC 86 Figure 15 Survival analysis of breast cancer...

Ngày tải lên: 09/09/2015, 18:56

... receptor and co-receptors and NT2 differentiation 2.3 19 30 34 GDNF AND BREAST CANCER Background 39 39 iv 3.2 Results 3.2.1 41 Expression of GFLs and their receptors in MCF7 human breast cancer ... involved in a variety of other cancers such as oral cancer [115, 116], pancreatic cancer [117119], lung cancer [119, 120], colorectal cancer [121, 122] and breast cancer 11 [123-125] The GDNF receptor ... neuronal lineages and study the roles of GDNF receptor system in neuronal differentiation and neuronal lineage specification 38 CHAPTER GDNF AND BREAST CANCER 3.1 Background Breast cancer is one...

Ngày tải lên: 30/09/2015, 10:11

... year for which breast cancer incidence is available (2005 for Republic of Ireland; 2004 for England & Wales, Scotland, Northern Ireland, and Sweden; 2003 for Czech Republic and Finland; 2001 for ... 2003 Figure 11 Breast Cancer in Women within Ages 45-49 in England & Wales, Scotland, Northern Ireland, Republic of Ireland, Sweden, Czech Republic, Finland, and Denmark; 1943-2005 Cancer registrations ... 1998 2003 Year Figure 12 Breast Cancer in Women within Ages 50-54 in England & Wales, Scotland, Northern Ireland, Republic of Ireland, Sweden, Czech Republic, Finland, and Denmark; 1943-2005 Journal...

Ngày tải lên: 06/03/2014, 02:21

... women to breast cancer – BRCA1, BRCA2 and TP53 The objective of this guideline is to decrease breast cancer morbidity and mortality by assessing hereditary risk in people before breast cancer develops ... that the woman understands what she can and cannot to modify her risk of breast cancer, and the effect this will have on her risk of other diseases and conditions Many of the risk factors are not ... guideline (‘Familial breast cancer: the classification and care of women at risk of familial breast cancer in primary, secondary and tertiary care’) gives details of the methods and the evidence...

Ngày tải lên: 15/03/2014, 00:20