2 fgf signaling in the growth plate
Hedgehog signaling in the zebrafish embryo role of kif7 and DZIP1 2
Ngày tải lên :
10/09/2015, 15:49
... aberrant Hh signaling (Pepicelli et al., 1998) Over expression of Hh can induce ectopic Hh signaling in cells which normally not respond to Hh (Concordet et al., 1996; Wolff et al., 2004) Hh signaling ... when Hh signaling is inhibited Based on this similarity, it was discovered that the compound cyclopamine can antagonize Hh signaling Consequently, it is now used routinely to inhibit Hh signaling ... existence of paralogs and novel components suggest that vertebrate Hh signaling is much more complicated 1.2 Drosophila Hedgehog Signaling Pathway In the Drosophila Hh pathway, there is one Hh ligand...
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Tài liệu Báo cáo khoa học: Roles of AP-2 transcription factors in the regulation of cartilage and skeletal development doc
Ngày tải lên :
16/02/2014, 09:20
... osteoblasts invade the cartilage and start to replace it with mineralized bone [48] Many molecules and signaling cascades are necessary to regulate these molecular processes of chondrogenic and skeletal ... transcription factors during chondrogenesis are illustrated in Fig AP-2a is expressed in the growth plate and in articular cartilage, and has been described as a negative regulator of chondrocyte ... and limbs [17–19] Donner et al tried to link the expression of AP-2a in these tissues to upstream signaling pathways They assessed the organization of a cis-regulatory region within the fifth intron...
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Tài liệu Báo cáo khoa học: Osmosensing and signaling in the regulation of mammalian cell function docx
Ngày tải lên :
18/02/2014, 16:20
... and trigger signaling pathways towards effector sites (‘osmosignaling’) Anisoosmotically exposed cells and tissues were frequently used as a model in order to study osmosensing and osmosignaling ... autophagic proteolysis [14] Thus, integrin-dependent cell volume sensing and signaling integrates into the overall context of insulin signaling Similarly, sensing of glutamine-induced hepatocyte swelling ... The findings localize endosomal acidification most upstream in the signaling cascade underlying hyperosmotic ROS production Osmosignaling in proliferation and apoptosis Growth factors stimulate...
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Tài liệu Báo cáo khoa học: Dual P2Y12 receptor signaling in thrombin-stimulated platelets – involvement of phosphoinositide 3-kinase b but not c isoform in Ca2+ mobilization and procoagulant activity pdf
Ngày tải lên :
18/02/2014, 16:20
... activates platelets, platelets become procoagulant, and more thrombin is formed at the surface of these platelets [9,10] Although ADP is considered to be a weak agonist, studies with human and mouse platelets ... FEBS Dual P2Y12 signaling in thrombin-stimulated platelets P E J van der Meijden et al A B Fig P2Y12 prolongs thrombin-induced Ca2+ responses partly via PI3-K signaling Fura-2-loaded platelets were ... 373 Dual P2Y12 signaling in thrombin-stimulated platelets P E J van der Meijden et al Table Contribution of P2Y12 signaling to thrombin- and ADP-induced Ca2+ responses Fura-2-loaded platelets (1...
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A study in the growth mechanism of silicon nanowires with or without metal catalyst
Ngày tải lên :
16/03/2014, 15:09
... temperature And growth rate can be controlled even can be self-organized with the assistance of template Thus it provides an operable route to combine with present nano-techniques for real applications...
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Báo cáo hóa học: "Involvement of aryl hydrocarbon receptor signaling in the development of small cell lung cancer induced by HPV E6/E7 oncoproteins" ppt
Ngày tải lên :
18/06/2014, 16:20
... Canonical pathway analysis of transgenic SCLC revealed the Aryl Hydrocarbon Receptor Signaling as the most significant signaling pathway modulated by E6/ E7 expression (p-value 1.89 × 10-7) Fifty-one ... highlighted the aryl receptor signaling involvement in other pathophysiological conditions Outside its well-characterized role, the AHR also functions as a modulator of cellular signaling pathways AHR ... pathway analysis We then used Ingenuity Pathways Analysis to highlight the cellular functions and signaling pathways affected by the E6/E7 co-expression Page of 11 The analysis of 5307 differentially...
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Báo cáo y học: "Antigen receptor signaling in the rheumatic diseases" doc
Ngày tải lên :
09/08/2014, 01:22
... in signaling mutants Mouse models An extensive mouse model literature can teach us about the signaling requirements for tolerance and autoimmunity Evidence for the role of antigen receptor signaling ... consequences of strong TCR signaling Examples of dramatically enhanced TCR signaling, including the Lck Y505F mutant and the Csk–/– mutant, exist [5] Both have such enhanced TCR signaling that T-cell ... Multiple pathways feed into this network at several proximal signaling nodes, including positive and negative regulators of antigen receptor signaling In T cells, for instance, the coreceptors CD4...
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