18  finding the structural auxiliary abstract and 88 classes

... shown in Fig The findings from these experimental investigations corroborate the data from the clinical study, where an inverse correlation of intrathecal TNF and IL-18 levels during the first 14 ... injury to the left hemisphere Mice received supporting oxygenation with 100% O2 until they awakened and were then brought back to their cages Control animals were subjected to anesthesia and sham ... 405 nm The experimental part of the study was set-up on two different protocols with the aim to assess the TNF-dependent regulation of IL-18 in the murine brain: (1) The first part of the experimental...

Ngày tải lên: 19/06/2014, 22:20

... investigation of the catalytic mechanism and substrate specificity and to understand the differences therein for this class of enzymes In order to identify the subsites of the ervatamins and to understand ... backbone of residues 65–64 and is partly exposed to the solvent (Fig 2B) On the other hand, the P3 moiety of E-64 in each of the of the two ervatamin-C molecules in the asymmetric unit mainly ... using the programs cns [58] and detwin and sfcheck in the CCP4 suite [59] confirmed that the data were twinned, and allowed us to calculate the twinning fraction (0.394) (Fig 6A,B) and the twinning...

Ngày tải lên: 18/02/2014, 16:20

... English: If the Pope is here, then the Queen and the Russian are also here hypothesis The Pope is here hypothesis The Queen and the Russian are both here The Russian is here ⇒-elim (lines and 2) &-elim ... R) hypothesis P hypothesis The Pope is here Q&R ⇒-elim (lines and 2) The Queen and the Russian are both here R &-elim (line 3) The Russian is here If the Pope is here, then the Queen and the Russian ... hypotheses have been verified earlier in the proof (And the lines where the hypotheses appear are written in parentheses after the name of the theorem.) For example, the theorems “⇒-elim” and...

Ngày tải lên: 21/02/2014, 09:20

... hidden) issue in the discussions of the future of the Internet, including the prospects for retaining the “end-to-end” principle The debates about open access and peering are really about the extent ... $700 and $1,000 will only attract Bob as a buyer, and again will not bring in the required $1,500, and any price above $1,000 will find no buyers at all On the other hand, if Charlie can sell the ... repeatedly by the courts, and landlords have won lawsuits filed by lawyers they refused to rent apartments to (Thus it is legal to discriminate against lawyers!) On the other hand, many cities in the U.S...

Ngày tải lên: 06/03/2014, 21:20

... N-terminal fragment and the first AAA-cassette of PEX6 (PEX6N + D1–GAL4-BD) Neither of the cassettes alone nor the two AAA-cassettes together or the N-terminal part together with the second cassette ... the binding sites of these two AAA-proteins to their different protein regions and elucidated the importance of ATP-binding to the two AAA-cassettes of Pex1p and Pex6p for their interaction The ... each other and for ATP and form the stable core of the NSF oligomer In contrast, the well conserved cassette (D1) of NSF accounts for the majority if not all of the ATPase activity of the NSF...

Ngày tải lên: 07/03/2014, 16:20

... GMD, both the P aeruginosa and A thermoaerophilus RMD sequences have gaps in the region of the RR loop, and in the His6-RMDAt structure, the b2–b3 loop is notably shorter than in GMD The truncation ... enough time for complete conversion of the GDPd-Man, and then removed the enzyme by filtration His6-RMDPa and NADPH were then added to the reaction mixture The GDP-6-deoxy-d-lyxo-hexos-4ulose substrate ... and light sand, respectively; the APPR portion of the cofactor (dark gray) and the ligand analog GDP-DMan (light gray) are represented as space-filling models Termini and secondary structural...

Ngày tải lên: 16/03/2014, 01:20

... for the eye The dashed line corresponds to the band-gap for the undoped Si-nw Fig 11 shows how the FE for the B and P codoped Si-nw changes as function of the position of the dopants within the ... are present in the literature They are mainly concentrated on H-passivated or pristine Si-nw and demonstrate the dependence of the energy band-gap from the wire diameter and from the surface morphology ... HOMO and LUMO states reveal their localization within the Si-nc, in particular the HOMO state is localized on the B impurity, while the LUMO is localized on the P one [17] The presence of these...

Ngày tải lên: 16/03/2014, 15:15

... the exposure of the hydrophobic core of Phe12, Aib15 and Val18 to the solvent, while establishing the structural basis for the side-chain interaction of the charged residues Arg16 and Glu20 The ... electrostatic charges on the surface and along the principal axis of the molecule In the synthetic CRH analogue, as in native peptide, there are seven negatively charged (six Glu and one Asp) and four positively ... disallowed regions of Ramachandran plot (Table and Fig S2) According to the PROCHECK-NMR [37] program, the average of the 40 models and the mean minimized structure of the synthetic analogue [D-Phe12,...

Ngày tải lên: 17/03/2014, 10:20

... structure and turn regions that differ in size and conformation and, in the more divergent cases, these differing regions may form half or more of each structure For proteins placed together in the ... clear their common evolutionary relationship CLASS For convenience of users, the different folds have been grouped into classes Most of the folds are assigned to one of the five structural classes ... and Macintosh platforms JMB—MS 422 539 Communication theoretical models, nucleic acids and carbohydrates, have been assigned to other classes The number of entries, families, superfamilies and...

Ngày tải lên: 23/03/2014, 12:20

... licheniformis (BLXI), for the moderate thermophile Thermoanaerobacterium thermosulfurigenes (TTXI), and for the hyperthermophile Thermotoga neapolitana (TNXI) Results indicate that the roles that divalent ... [20–23] and have been shown to be essentially identical, which explains the similar biochemical and thermostability properties of these enzymes [7] Comparisons between the structures of the most thermostable ... stabilization of BLXI and TTXI relative to their apo forms, the effect was smaller for ECXI and almost negligible for TNXI (Fig 2) The melting temperatures (Tm, the temperature at the maximum of the heat...

Ngày tải lên: 23/03/2014, 13:20

... lactis The results are presented in Table and Fig 4A For the cluster of lowest energy, both the position and the conformation of the ligand are close to those observed in the 3D structure of the ... the OH atom of Tyr380 and the carbonyl group of the ligand Finally, the valine side chain of the ligand, pointing towards the active site cavity, shows only low hydrophobic interaction with the ... comparison of the active and specificity sites of the two X-PDAP enzymes, the bacterial PepX (green) and the human DPP-IV (orange) (B) Superposition of the active and specificity sites of the S9 enzymes...

Ngày tải lên: 23/03/2014, 13:20

... separate languages For the active corpus, zero-reversible inference groups the forms of with the other modals The D F A s for the passive and full corpora also contain loops and thereby generate infinite ... ZERO-REVERSIBLE OF THE ENGLISH OVERGENERALIZATION AUXILIARY SYSTEM Figure I: The top automaton generates the English auxiliary system Zero-reversibleinference merges state with state and merges states and with ... derives from the systematic sequential structure of the English auxiliary system In an idealized form (ignoring tense and inflections) the regular expression euce, Does treating the English auxiliary...

Ngày tải lên: 24/03/2014, 01:21

... leadership, the ability to present their point of view persuasively – even when it’s contrary to the views of others – and an understanding of the needs and motivations of both their firm and its ... directors and executive directors – the titles are used interchangeably – the top rung of the ladder is within reach These men and women are the right hands of investment banking’s leaders, the managing ... interview at the career center and beg them to be harsh The single most effective thing you can to stand out during interviews and campus events is to study up on the companies and the people you’re...

Ngày tải lên: 29/03/2014, 18:20

... K8 and D72 are located near the crossing region of the helices, and the Nx atom of K8 is found ˚ at a distance of 6.2 A from the nearest side-chain oxygen of D72 Taking the functionally and structurally ... twostate equilibrium model (NfiU) The experimental DSC curves, together with their best fits, for the thermal unfolding of wild-type cyt c6, and for the mutants D72K and D72A ⁄ K8D at pH 5.0 are shown ... neutral residue, when the negative charge at position 72 was removed The influence of the nature of the introduced mutations and the complex pH dependence of the DGint values for the different mutant...

Ngày tải lên: 30/03/2014, 20:20

... band very close to the LH1 a band, indicated by the arrow, is apparent in the PufX54* mutant (lane 6) This band was excised from the gel after SDS/PAGE and the protein was identified by using the ... ambiguous the attribution of the PufXD2)19 strain to the wild-type or the PufDX cluster Isolation of the photosynthetic complexes from the mutant strains As described previously [16], the photosynthetic ... 180 mV (i.e when the ubiquinone pool is fully oxidized) and reflect a dramatic impairment in the redox interaction between the QB site of the RC and the Qo site of the cyt bc1 in the pufX-deleted...

Ngày tải lên: 31/03/2014, 09:20

... Cheyennes and Arapahos, mostly the old, the young, and the weak During the afternoon and the following day, the soldiers wandered over the field, committing atrocities on the dead, before departing the ... of the Southern Cheyenne and Arapaho Tribes of Oklahoma, the Northern Cheyenne Tribe, and the Northern Arapaho Tribe As part of the site-location process, Cheyenne and Arapaho descendants of Sand ... passed the Sand Creek Massacre National Historic Site Study Act, which directed the NPS to work with the Northern Cheyenne Tribe, the Northern Arapaho Tribe, and the Southern Cheyenne and Arapaho...

Ngày tải lên: 11/06/2014, 13:09

... feature of the type-I band transition Therefore, the interband transition of the GaSb QD would be the only proper origin of the high-energy peak In the growth process of the sample, the InGaAs ... blocked by the GaSb barrier and will not enter the QDs Therefore, this structure will prolong the lifetime of the holes So, the QD-FET based on the above band structure can be used to improve the sensitivity ... measurement SZ, TH, and GH conducted the MBE growth JH, WW, and CH coordinated the study WL provided the idea and conceived the study together with ZL All authors read and approved the final manuscript...

Ngày tải lên: 20/06/2014, 20:20

... (a) The location and the size of the Au catalyst, the present of Au catalyst, is demonstrated the VLS method (b) The HR-TEM and SAED pattern (inset) reveal the (103) primary growth plane of the ... focused onto 1, 3, and 5SZO targets for the deposition The laser influence was set to 1.2 J/cm2, and the shot area on the target surface was 0.042 cm2 Before the deposition, there should be pre-deposition ... from the near band-edge emission (NBE) of ZnO-based NWs are observed at around 3.351, 3.356, and 3.358 eV The temperature-dependent PL of the SZO provides the reference for the PL analysis of the...

Ngày tải lên: 20/06/2014, 22:20

... light the sensitizing effect of Si-np towards Nd3+ ions The evolution of the integrated PL intensity of the Sinp PL band and the 920-nm PL peak is shown in the inset of Figure The enhancement of the ... chips The Nd content was monitored by the surface ratio between the Nd2O3 chips and the SiO2 target The sputtering gas was a mixture of argon and hydrogen; the latter enables us to control the ... underlines the strong coupling between Si-np and Nd 3+ ions, and, accordingly, the potential of sensitizing of Si-np The increase of the PL intensity of Nd 3+ is then explained by the increase of the...

Ngày tải lên: 21/06/2014, 05:20

... the STEM measurement SZ, TH, and GH conducted the MBE growth JH, WW, and CH coordinated the study WL provided the idea and conceived the study together with ZL All authors read and approved the ... with the 2DEG, electrons will still be blocked by the GaSb barrier and will not enter the QDs Therefore, this structure will prolong the lifetime of the holes So, the QD-FET based on the above band ... of the excitation power which is a typical feature of the type-I band transition Therefore, the interband transition of the GaSb QD would be the only proper origin of the highenergy peak In the...

Ngày tải lên: 21/06/2014, 17:20