13 1 viewing the properties file in creator s editor pane
Báo cáo khoa học: A modelling approach to quantify dynamic crosstalk between the pheromone and the starvation pathway in baker’s yeast pot
Ngày tải lên :
30/03/2014, 10:20
... Ste12 Ste12 v1 Ste 11 v7 v8 c9 Kss1 Ste12 Kss1 Kss1 c Ste12 Ste12 17 Ste 11 v26 c4 Kss1 c 15 PP v4 Gβγ Ste5 P Kss1 Kss1 Ste 11 v1 Gβγ c12 c7 Tec1 FREP c24 v 31 Fig Graphical representation of the ... c 11 v14 Ste 11 v9 Starvation (β) c1 c3 v3 Fus3 c6 v15 Gβγ Gβγ c1 Ste5 Kss1 Ste5 Ste 11 Fus3 c14 v1 c15 Kss1 PP Ste5 Ste 11 v1 Fus3 c1 c6 Fus3 Kss1 v16 v6 nucleus P c8 v17 v5 c18 Fus3 PP v16 Gβγ Ste5 ... c1 c15 Kss1 PP P P Gβγ Ste5 c15 Kss1 PP Ste12 Ste12 v2 Ubi Ste 11 PPP c1 Ste12 Kss1 c23 c19 c1 c22 Tec1 PREP c20 Ste12 v25 v2 c1 Fus3 P P c9 v30 P Kss1 v2 v23 v28 c2 Tec1 v 21 v22 v18 Kss1 c12 Ste12...
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1.5 Thế giới công bằng World''s fair
Ngày tải lên :
10/09/2015, 12:03
... Melbourne 18 84 New Orleans 18 93 Chicago 19 01 Buffalo 19 04 St Louis 19 07 Dublin • • • • • • • • • • • • • • • • • • • • • (United States) (United States) 19 10 Brussels (Belgium) 19 11 Turin (Italy) 1 913 ... (United States) (United States) 19 29 Seville (Spain) 19 29 Barcelona (Spain) 19 30 Liège (Belgium) 19 30 Antwerp (Belgium) (United States) 19 35 Brussels (Belgium) 19 37 Paris (France) (United States) 19 39 ... (United States) 19 58 Brussels (Belgium) (United States) (United States) (not BIE sanctioned) (Canada) 19 07 Norfolk 19 09 Seattle 19 15 San Francisco 19 15 San Diego 19 33 Chicago 19 39 New York City 19 39 19 40...
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1.5 Thế giới công bằng World''s fair
Ngày tải lên :
10/09/2015, 12:03
... States) 19 09 Seattle (United States) 19 10 Brussels (Belgium) 19 11 Turin (Italy) 1 913 Ghent (Belgium) 19 15 San Francisco (United States) 19 15 San Diego (United States) 19 29 Seville (Spain) • • • • 19 33 ... 18 84 New Orleans (United States) 18 85 Antwerp (Belgium) • • • 18 93 Chicago (United States) • 18 97 Brussels (Belgium) • • 19 01 Buffalo (United States) • • • • 18 88 Barcelona (Spain) 18 89 Paris ... 19 68 San Antonio (United States) 19 70 Osaka (Japan) 19 74 Spokane (United States) 19 82 Knoxville (United States) 19 84 New Orleans (United States) 19 85 Tsukuba (Japan) 19 86 Vancouver (Canada) 19 88...
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Tài liệu Báo cáo khoa học: Abstract Integration of Metabolism and Survival PP-1 The metabolic switch in liver methionine metabolism pptx
Ngày tải lên :
19/02/2014, 07:20
... Analysing the status of vessels inside the tumours, KO animals displayed a five-time fold decrease in the total vessel area, maintaining a similar vessel number Tumour vessels in KO animals seemed ... unclear In the other hand, Escol cells are resistant to IFN-alpha Excuses behind these distinct responses of two cell lines were investigated in this study The focus of this research was to determine ... those published, suggest that NO-cGMP signaling pathway (s) are involved in stress-impaired testicular steroidogenesis PP -13 Estrogenic effects of natural and synthetic compounds assessed in Saccharomyces...
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Tài liệu Báo cáo khoa học: Fra-1 targets the AP-1 site/2G single nucleotide polymorphism (ETS site) in the MMP-1 promoter docx
Ngày tải lên :
21/02/2014, 00:20
... MMP -1 mRNA [15 ] We also determined that continuous synthesis of new proteins is necessary for MMP -1 expression [15 ] and that the levels of these proteins are decreased when ERK 1/ 2 signaling is ... from )12 3 bp to ) 61 bp, to which Fra -1 binds [39] These studies have suggested that Fra -1 interacts with Ets transcription factors to induce MMP -1 gene expression The present study extends these ... (Gene Therapy Systems) To further elucidate the role of AP -1 sites in the MMP -1 promoter, reporter constructs containing mutations in selected AP -1 sites were used [15 ,20] To alter the expression...
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look at the important information in this header.1look at the important information in this header.We encourage you to keep this file on your own disk, keeping an electronic path open for the next readers. Do not remove this. **Welcome To The World o doc
Ngày tải lên :
06/03/2014, 23:21
... past "The Republic, as it was dreamed of in July," she writes, "has ended in the massacres of Warsaw and in the holocaust of the Saint-Merry cloister The cholera has just been raging Saint Simonism ... protested against the accusation of having aimed at attacking institutions in her feminist novels She was wrong in protesting, as it is just this which gives her novels their value and significance ... daring in days of battle; shrewd and clever in seizing the loose threads of ordinary life, but silly and stupid in distinguishing her own interests when it is a question of her happiness; caring...
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Báo cáo khoa học: SAF-3, a novel splice variant of the SAF-1/MAZ/Pur-1 family, is expressed during inflammation pptx
Ngày tải lên :
07/03/2014, 02:20
... SAF -1 and SAF-3 proteins For bacterially expressed SAF -1 and SAF-3 proteins, the corresponding cDNAs were subcloned into the pRSET vector (Invitrogen) Proteins expressed from these constructs ... N-terminus In addition, a portion of the first exon constituting the N-terminus of SAF -1/ SAF-2 mRNA is deleted in SAF-3 mRNA (Figs and 2) In previous studies, this region of SAF -1/ SAF-2 was shown ... normal synovium (Fig 4, lanes and 2) SAF -1 expression was detected in normal tissues and was slightly elevated in both disease conditions This result is consistent with previous findings indicating...
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Báo cáo khoa học: Insulin induces heme oxygenase-1 through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in renal cells pptx
Ngày tải lên :
07/03/2014, 12:20
... mouse primary renal tubular epithelial cells 2346 Results Insulin increases HO -1 expression in ACHN cells Treatment of serum-deprived ACHN cells with increasing concentrations of human insulin ... insulin was abolished Similarly, cycloheximide (CHX) was administered to establish the role of protein synthesis in insulin-induced HO -1 expression (Fig 2B,C) CHX abrogated HO -1 protein induction ... Insulin increases HO -1 expression in mouse primary renal tubular epithelial cells In order to ensure that insulin-induced HO -1 expression was not a characteristic of transformed cells alone, mouse...
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Báo cáo khoa học: Essential role of the C-terminus in Melanocarpus albomyces laccase for enzyme production, catalytic properties and structure pdf
Ngày tải lên :
16/03/2014, 00:20
... 22.5 17 .0 20 .1 27.0 32.0 27.8 19 .1 16.4 21. 4 31. 9 11 .2 – 18 .3 18 .7 22 .1 32 .1 13 . 8 – 11 .9 11 .7 10 .1 15.2 24.4 26.0 12 .3 11 .7 10 .5 15 .4 23.9 25.3 Sc(L559A) mutant at least partly loses its chloride ... undergoing processing has been shown to be a Leu C-terminal processing has also been shown for the basidomycete laccase from Coprinus cinereus, but the processing is distinct from that of the ascomycete ... Myceliophthora thermophila [19 ] The processing site for all of these laccases is Asp-SerGly-Leu Interestingly, a similar type of sequence is found in the C-termini of other ascomycete laccases that not...
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Báo cáo khoa học: Role of the structural domains in the functional properties of pancreatic lipase-related protein 2 pot
Ngày tải lên :
16/03/2014, 06:20
... controls The chimeric proteins were expressed in insect cells using the Baculovirus Expression System The four proteins were secreted into the culture medium with yields reaching 10 –40 mg of recombinant ... site was better in the protein bearing the N2 domain than in the protein bearing the Nc domain Thus, the accessibility of the active site in the N2 proteins was independent of the nature of the ... of bile salts The specific activity of hoPL is 8000 UÆmg )1 (in the presence of colipase) In the absence of bile salts, the proteins containing the same N-terminal domain show a similar specific...
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Báo cáo khoa học: The properties of phosphodiesterase 11A4 GAF domains are regulated by modifications in its N-terminal domain pptx
Ngày tải lên :
16/03/2014, 06:20
... mutants in human PDE11A4 tandem GAF domain constructs Chimeric construct EC50 cGMP (lM) Maximal stimulation (fold) PDE 11 ⁄ cyaB1 (wild-type) S 117 D S1 62D S 117 D ⁄ S1 62D S 117 E S1 62E S 117 E ⁄ S1 62E ... used phosphomimetic mutations and replaced both residues with either aspartate or glutamate Single mutations of Ser 117 (S 117 D and S 117 E) or Ser162 (S1 62D and S 116 2E) resulted in slight increases ... means ± SEM (n ‡ 4) s, chimera starting at Lys197 [PDE11A4 (19 7-568)cyaB1 AC]; d, chimera starting with Lys198 [PDE11A4 (19 8568)cyaB1 AC] In several points the error is within the limits of the symbol...
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Báo cáo khoa học: Analysis of the regulatory motifs in eukaryotic initiation factor 4E-binding protein 1 pot
Ngày tải lên :
16/03/2014, 06:20
... variants containing the indicated (putative) TOS motifs from other proteins (as noted) were expressed as GST fusions in Escherichia coli Binding to raptor was assessed using the overlay assay (top section) ... consistent with the fact that this residue is isoleucine in S6 K1, and suggesting that a bulky side-chain is needed here It is therefore interesting that the only other known TOS motif, in S6 K2, ... leucine in the first position, and methionine, isoleucine or probably similar residues in the third) The requirements at the other positions are less strict: in the second and fourth positions,...
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Báo cáo khoa học: Alternative initiation of transcription of the humanpresenilin 1gene in SH-SY5Y and SK-N-SH cells The role of Ets factors in the regulation ofpresenilin 1 pptx
Ngày tải lên :
16/03/2014, 18:20
... mutations in Ets and Sp1 motifs on PS1 promoter activity The positions of Ets (d) and Sp1 (h) motifs in the )11 9/ +17 8 region of the PS1 promoter are indicated The positions relative to the +1 site ... footprinting experiments The Ets and Sp1 consensus motifs are underlined Arrows indicate the end points of 5¢ or 3¢-deletions SacII restriction enzyme sites used in the preparation of the probes used ... cases All constructs were tested in at least three different experiments The )11 9/ +17 8 construct was taken as 10 0% (B) RACE in SH-SY5Y and SK-N-SH cells transfected with the ( )19 9/ +17 8) PS1 promoter...
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Báo cáo khoa học: Retention of the duplicated cellular retinoic acid-binding protein 1 genes (crabp1a and crabp1b) in the zebrafish genome by subfunctionalization of tissue-specific expression doc
Ngày tải lên :
16/03/2014, 22:20
... other tissues examined including the liver, ovary, skin, intestine, heart, muscle and testis crabp1b mRNA was detected by RT-PCR in the skin, intestine, brain and muscle of adult zebrafish As ... retinoid-binding proteins In The Retinoids: Biology, Chemistry and Medicine, 2nd edn (Sporn MB, Roberts 3569 Duplicated crabp1 genes in zebrafish 10 11 12 13 14 AB & Goodman DS, eds), pp 283– 317 Reven Press, ... tissues including the brain, spinal cord, liver, ovary, testis, uterus, adrenal gland and retina [1] In the present study, we observed differential patterns of crabp1a and crabp1b expression in...
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Báo cáo Y học: Two 1 : 1 binding modes for distamycin in the minor groove of d(GGCCAATTGG) docx
Ngày tải lên :
24/03/2014, 04:21
... contacts including interactions between the guanine amino groups and the terminal distamycin atoms Such amino-group interactions are often assumed to be repulsive steric clashes To clarify the nature ... interactions Distamycin binds in the minor groove of the central octamer The expected binding site of at least five base pairs makes interactions with GC base pairs inevitable Both structures not only ... H (19 79) Netropsin, a DNA-binding oligopeptide structural and binding studies Biochim Biophys Acta 5 61, 12 4 13 1 14 Allen, F.H & Kennard, O (19 93) 3D search and research using the Cambridge Structural...
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Hướng dẫn khắc phục lỗi “username is not in the sudoers file...” trong Ubuntu doc
Ngày tải lên :
30/03/2014, 00:20
... /etc/sudoers.d/ instead of # directly modifying this file # # See the man page for details on how to write a sudoers file # Defaults env_reset # Host alias specification # User alias specification ... /etc/sudoers.backup sudo nano /etc/sudoers - Và nhập đoạn mã vào file hiển thị: # # This file MUST be edited with the 'visudo' command as root # # Please consider adding local content in /etc/sudoers.d/ ... theo, chọn Check all file systems - Nhấn Enter hệ thống hiển thị thông báo: Finished, press Enter - Tiếp theo, chọn Drop to root shell prompt: - Khi hình Command Prompt hiển thị, gõ lệnh: usermod...
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Báo cáo khoa học: The C-terminal region of the proprotein convertase 1⁄ 3 (PC1⁄ 3) exerts a bimodal regulation of the enzyme activity in vitro pdf
Ngày tải lên :
30/03/2014, 08:20
... properties are solely ascribed to N-terminal domains, thus rendering intriguing the possibility that PC1 ⁄ CT-peptide might by itself possess intrinsic inhibiting properties Production of recombinant ... extrinsic factor that binds to particular sites of the enzyme In the case of PCs, it has been previously shown that potassium ion is able in vitro to stimulate the processing of ‘good’ substrates ... Recombinant murine PC1 ⁄ was produced using the baculovirus expression system in Sf9 insect cells [7] or through intracoelemic injection in insect larvae [44] Once expressed, the enzyme was recovered...
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Báo cáo khoa học: Salt-inducible kinase-1 represses cAMP response element-binding protein activity both in the nucleus and in the cytoplasm pdf
Ngày tải lên :
30/03/2014, 15:20
... of resting Y1 cells In ACTH-treated cells, SIK1 is phosphorylated at Ser577 by PKA, and the phospho-SIK1 moves to the cytoplasm within 10 The phospho-SIK1 is then dephosphorylated, and SIK1 re-enters ... phosphorylation sites, Ser577 in SIK1 and Ser587 in SIK2, are indicated in bold The basic residues in domain 3B are indicated by underlines The similarity between SIK1 and SIK2 in domain 3A, the ... transcriptional repression activity of SIK1 (1 708), another mutant localizing exclusively in the nucleus (shown in Fig 1B) The SIK1 (1 708) expression plasmid, pIRESSIK1 (1 708), was co-introduced with the CRE–reporter...
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Báo cáo Y học: Expression of the uncoupling protein 1 from the aP2 gene promoter stimulates mitochondrial biogenesis in unilocular adipocytes in vivo potx
Ngày tải lên :
31/03/2014, 15:20
... contained UCP1 These ®ndings thus con®rmed our previous observations in aged transgenic animals [16 ] The staining for UCP1 was always restricted to the cytoplasmic area in the vicinity of the plasma ... comparisons was used as described before [17 ] Otherwise, statistical signi®cance was evaluated using Student 's t-test The morphometric measurements were evaluated using the Kruskal±Wallis nonparametric ... (Sigma) The speci®city of the method was tested by the omission of the primary antibody in the staining, and the use of preimmune serum instead of the ®rst antiserum Furthermore, tissues known...
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