1 00 g of 2a was dissolved in 40 ml of toluene the mixture was stirred at 70 c for 1 0 hr after adding 0 1 ml of tert butyl peroxide 2 00 g of 6 was then su

Studies on the anti cancer potential of sesquiterpene lactone parthenolide

Ngày tải lên : 16/09/2015, 17:14

... 3µM) of parthenolide (Wen et al., 20 0 2 ) All these studies 15 indicated that, at sub-lethal concentrations, parthenolide could inhibit cell growth by inducing cell cycle arrest at G2 /M 1. 1.4 in ... to elucidate the precise role of COX -2 in cancer development Autocrine Paracrine Adapted from Nat Rev Cancer Gupta and Dubois ( 20 01 ) Fig 1. 10 Cyclooxygenase -2 promotes cancer formation In summary, ... al., 19 96) The death effector domain at the N-terminal end of FADD then interacts with corresponding death motif on the prodomain of pro-caspase or caspase 10 to form the deathinducing signaling complex...

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Human telomerase reverse transcriptase (hTERT) overexpression modulates intracellular redox balance and protects cancer cells from apoptotic cell death

Ngày tải lên : 14/09/2015, 08:38

... these key regulators include AP1, SP1 and Nf-kB, all of which are redox regulated (Akiyama et al., 20 0 3 ; Cong and Shay, 20 0 8 ; Cong et al., 20 0 2 ; Poole et al., 20 01 ; Takakura et al., 20 0 5 ) AP1 ... oxidation to sulfinic acid (Cys-S02H) or sulfonic acid (Cys-S03H) which can result in the inactivation of the enzyme (Hofmann et al., 20 0 2 ; Wood et al., 20 0 3 a; Wood et al., 20 0 3 b) More recent studies ... put forth a new notion that Prxs may be critical regulators of peroxide mediated cell signalling by acting as a sulfinic acid switch (Jacob et al., 20 0 4 ) They suggest that this may occur since the...

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Tài liệu Báo cáo khoa học: Competition between innate multidrug resistance and intracellular binding of rhodamine dyes pdf

Ngày tải lên : 18/02/2014, 13:20

... Apparent concentrations ratio (cell/medium) 15 Rhodamine 12 3 TMR – CCCP 10 10 0 + CCCP On ice + CCCP 30 45 15 60 0 10 20 30 20 30 60 TMRM Rhodamine 6G 60 40 40 20 20 0 10 20 30 10 Time (min) Table ... 20 0 40 15 0 Rhodamine 12 3 TMR TMRM 10 0 60 + CCCP 50 10 10 0 20 On ice + CCCP 10 10 0 10 10 0 Dye concentration (µM) Fig Effect of rhodamine dye concentrations on their uptake into K5 62 cells K5 62 ... 30 20 30 60 TMRM 60 Rhodamine 6G 40 40 20 0 20 10 20 30 0 10 Time (min) Fig The effect of MK5 71 and NBD-Cl on TMRM distribution in K5 62 and 20 0 8 cell lines K5 62 cells and 20 0 8 cells were incubated...

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Tài liệu World Economic outlook - Financial Stress, Downturns and Recoveries ppt

Ngày tải lên : 18/02/2014, 16:20

... America6 20 0 0 70 Sep 08 06 Emerging Europe3 80 60 90 China India 12 0 Nominal Effective Exchange Rate Middle 11 0 Africa4 East5 10 0 70 12 0 11 0 10 0 80 13 0 10 0 02 04 06 08 20 0 0 02 04 06 Aug 08 Sources: ... Rate (index, 20 0 0 = 10 0) 14 0 13 0 Euro area United States 12 0 11 0 10 0 90 Japan 20 0 0 01 80 02 03 04 05 06 70 Sep 08 07 14 0 Real Effective Exchange Rate (index, 20 0 0 = 10 0) Euro area 12 0 United States ... 80 90 20 0 0 10 19 70 80 90 20 0 0 10 Real Commodity Prices (19 95 = 10 0) Consumer Prices 500 Emerging and developing economies (median) 20 400 Oil prices3 15 300 Food 20 0 10 19 70 16 10 0 Advanced economies...

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Tài liệu Báo cáo khoa học: Osmotic stress sensing and signaling in ﬁshes doc

Ngày tải lên : 18/02/2014, 16:20

... AAG2 8 02 9 .1) , aquaporin ( 323 amino acids, NP _0 01 6 41. 1), TonEBP (15 31 amino acids, NP _00 6 5 90 .1) , and the mouse sequence of TSC22D2-4 (11 6 amino acids, EU 00 415 1) were used as references and their conserved ... Nonnotte G ( 20 0 6 ) Volume regulation FEBS Journal 27 4 ( 20 0 7 ) 57 90 5798 ª 20 0 7 The Authors Journal compilation ª 20 0 7 FEBS 5797 Osmotic stress sensing and signaling in ﬁshes 26 27 28 29 30 31 32 33 ... IPT_NFAT, IPT domain of the NFAT family of transcription factors (cd 01 1 78); TSC 22, TSC -22 ⁄ dip ⁄ bun family (pfam 01 1 66 ); MIP, major intrinsic protein (cd 003 33); ANK, ankyrin repeats (cd 0 02 04);...

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Tài liệu Báo cáo Y học: Regulated expression and intracellular localization of cystatin F in human U937 cells pptx

Ngày tải lên : 21/02/2014, 01:21

... GTG CTG CCT GAG AAG GAT TG GAC AGG GGA GAA CGC CAC TTA GAA AGT GCC CTG GGG AAG ACC 57 62 587 333 TGA AGG CCC CAC TAA CAT CAG GAG GCC CTG CTT CCT AGT GGA TAT ATC CGC CCT GCT CTC CTA TGC GTT AGA ... GAC GTG GTG ACG 56 58 314 28 9 CCG CAG GGA AAG TCT AAG CTC CTT CTG CTG CCT GGT CTT GA ACA TCT CTG CTG ATT ATT CAG GCA CTT CAC CCG CTC ACT CGT CA 55 57 497 5 42 CGG CGA GTA CAA CAA AGC CA GGA GGT ... unusually high GC content (over nucleotides )1 to ) 10 00 , 50% ; nucleotides )1 to ) 300 0 , 45%) and comparing CpG to GpC gives a ratio of 1/ 5 By contrast, a ratio of 1, indicating a continuously...

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Stress symptoms and coping strategies in healthy elderly subjects pot

Ngày tải lên : 14/03/2014, 20:20

... 41 28 68 .3 Symptoms Deep sadness 41 28 68 .3 Social isolation 41 25 61 . 0 Back pain 41 24 58.5 Physical burnout 41 22 53 .6 Anger 41 21 51. 2 Muscle tension 41 20 48.9 These results suggest that the ... differences in strategies of coping and defense across the life span Psychol Aging 19 96 ;11 (1) : 12 7-39 Whitty MT Coping and defending: age differences in maturity of defense mechanisms and coping strategies ... symptoms and coping strategies in healthy elderly subjects Souza-Talarico JN, Caramelli P, Nitrini R, Chaves EC 10 0% problem emotion 80% 60 % 40% 20 % 0% Coping type Given that the elderly subjects were...

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Báo cáo khoa học: Critical roles of Leu99 and Leu115 at the heme distal side in auto-oxidation and the redox potential of a hemeregulated phosphodiesterase from Escherichia coli pptx

Ngày tải lên : 16/03/2014, 13:20

... 5¢-gatga gtcgggagACCcagctggagaaaaaag-3¢, 5¢-gatgagtcgggagTTTcag ctggagaaaaaag-3¢, 5¢-ggacccgttttgcgACCtcgaaagtgagc-3¢, and 5¢-ggacccgttttgcgTTTtcgaaagtgagc-3¢ Preparation of Ec DosH The (His )6- tagged ... – – 0 .00 6 3 0 .00 5 8 0 .00 5 3 0. 049 0. 37 0. 065 0. 33 0. 0 01 3 0. 0 01 7 0. 01 6 0. 0 51 0. 033 11 0 12 0 13 0 14 1. 9 11 2 .1 5 30 4 10 43 14 21 This [5] [13 ] This This This This [5] [5] [5] [13 ] [13 ] study study study ... 418 417 418 418 413 529 527 5 30 533 5 40 565 565 565 566 428 428 429 428 429 533 5 32 5 32 5 31 535 563 564 563 5 62 563 424 423 425 423 423 5 41 5 41 543 5 40 5 41 5 71 574 574 5 70 5 72 (11 0) (11 2) (11 2) ...

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Báo cáo Y học: A Ca2+/CaM-dependent kinase from pea is stress regulated and in vitro phosphorylates a protein that binds to AtCaM5 promoter ppt

Ngày tải lên : 18/03/2014, 01:20

... GTAGTATTAAAAAGTAGTAGTTAAAAGC-3¢; Oligo III, 5¢-GTTTTTATCCGATGCAAATTTTTGCTTTGT GATTG-3¢ The reaction was performed in 20 lL DNA-binding buffer containing ( 50 mM Tris pH 7.4, 50 mM KCl, mM dithiothreitol, 6% glycerol, ... Interaction of plant chimeric calcium/calmodulin-dependent protein kinase with a homologue Ó FEBS 20 0 2 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 Role of PsCCaMK in stress signaling ... sulfate saturation The suspension was centrifuged at 10 0 00 0 g for h in a Beckman Ti 75 rotor The supernatant obtained was brought to 70% saturation and the nuclear proteins were obtained by centrifugation...

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Báo cáo khoa học: Relaxin-3⁄ insulin-like peptide 7, a neuropeptide involved in the stress response and food intake Masaki Tanaka pptx

Ngày tải lên : 29/03/2014, 21:20

... relaxin, suggesting that RXFP1 was involved in this action [35] Concerning the chronic administration of relaxin-3, intracerebroventricular injection for 14 days ( 60 0 pmolÆday )1) using osmotic minipumps ... for GPCR1 42 J Biol Chem 27 8, 507 65 – 50 7 70 Hudson P, Haley J, Cronk M, Shine J & Niall H (19 81) Molecular cloning and characterization of cDNA sequences coding for rat relaxin Nature 2 91, 12 7 13 1 ... S, Gundlach AL & Tregear GW ( 20 0 2 ) Restricted, but 15 16 17 18 19 20 21 22 abundant, expression of the novel rat gene-3 (R3) relaxin in the dorsal tegmental region of brain J Neurochem 82, 15 53 15 57...

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oxidative stress biomarkers and antioxidant protocols

Ngày tải lên : 11/04/2014, 10:00

... 23 6 27 ,00 0 12 -HETE 23 7 27 ,00 0 12 -HpETE 23 7 27 ,00 0 18 -HETE 23 7 27 ,00 0 18 -HpETE 23 7 27 ,00 0 15 -HETE 23 6 27 ,00 0 15 -HpETE 23 6 27 ,00 0 Internal Standard (I.S.) 18 Ϻ3 23 6 27 ,00 0 21 5 ? 22 6 20 4 21 5 21 4 ... octadecadieneoic acid (linolenic acid) Absorbance maximum Molar extinction coefﬁcient 13 -HOTE 23 5 23 ,00 0 13 HpOTE 23 5 23 ,00 0 13 -HODE 23 4 23 ,00 0 19 -HODE 23 4 23 ,00 0 13 -HpODE 23 4 23 ,00 0 19 -HpODE 23 4 23 ,00 0 15 -HETE ... Gavin, 20 01 1 60 Nuclease Methods and Protocols, edited by Catherine H Schein, 20 01 159 Amino Acid Analysis Protocols, edited by Catherine Cooper, Nicole Packer, and Keith Williams, 20 01 158 Gene...

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báo cáo hóa học: " Occurrence of post traumatic stress symptoms and their relationship to professional quality of life (ProQoL) in nursing staff at a forensic psychiatric security unit: a cross-sectional study" potx

Ngày tải lên : 18/06/2014, 18:20

... Ward cross tabulation years C F Total 0 3 9.5% 18 .2% 31. 3% 18 .2% 13 18 ,6% 14 .3% 18 .2% 18 .8% 18 .2% 12 17 ,1% 7–9 14 .3% 22 .7% 0% 0% 11 ,4% 10 12 4.8% 9 .1% 6. 3% 0% 5,7% over 12 Total N B 4 6 Length of ... http://www.hqlo.com/content/7 /1/ 31 28 26 44 40 22 36 BurnOut Scale Compassion Satisfaction Scale 24 32 28 20 18 16 14 24 12 10 20 A B C F Wards A B C F Wards Figure scores on CS at the different ... (95% CI 22 .4 28 .4), ward B; 19 .7 (95% CI 18 .3– 21 . 1), ward C; 19 .7 (95% CI 18 .1 21 . 3), ward F; 21 . 7 (CI 95% 17 .6 25 .9), df = 3 :66 , F-value = 6 .03 , p = 0 01 , thus indicating a higher rate of PTSD...

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báo cáo hóa học: " Prevalence of stress, anxiety and depression in with Alzheimer caregivers" ppt

Ngày tải lên : 18/06/2014, 19:20

... Activities of Daily Living; CBI: Caregiver Burden Inventory http://www.hqlo.com/content /6 /1/ 93 10 11 12 13 14 15 16 17 18 Competing interests The authors declare that they have no competing interests ... Ig 20 0 2 , 14 (3) :22 3 -23 2 Pucci E, Bricioli E, Gainotti G, Provinciali L, Scarpino O, Trabucchi M: Malattia di Alzheimer: Manuale per gli operatori Milano Franco Angeli 20 0 4 Lepp M, Ringsberg KC, ... 6: 93 The Service was commenced in the year 20 0 0 and, up to now, 768 records have been collected, of which 563 referring to patients effectively registered in the Cronos Plan; the remaining 20 5 ...

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báo cáo hóa học:" Psychosocial stress, demoralization and the consumption of tobacco, alcohol and medical drugs by veterinarians" ppt

Ngày tải lên : 20/06/2014, 00:20

... (2. 4 22 .9) Working Hours ≤ 20 h per week 21 40 h per week 41 60 h per week ≥ 60 h per week 4 .2 1. 5 7.5 24 .7 2. 8 (0. 6 12 .8) 5 .2 (1. 9 14 .7) 21 . 0 (7.3– 60 . 3) 2. 4 (0. 5 10 .9) 5 .2 (1. 8 14 .6) 16 .4 (5.7–47.8) ... Employee in a practice 15 .4 18 .5 28 .0 1. 2 (0. 8 1. 8) 2 .1 (1. 4–3.3) 1. 2 (0. 8 1. 7) 1. 6 (1. 0 2. 6) Psychosocial Stress Low (1 18 points) Intermediate (19 – 36 points) Intense (37–53 points) 14 .4 22 .8 34 .1 1.8 ... Psychiatry 19 74, 13 1 :11 21 - 1 12 3 Augustin R, Semmler C, Rösner S, Kraus L: Use and misuse of prescription medications Results of the 20 0 3 Epidemiological Survey of Substance Abuse Sucht 20 0 5 , 51: S49-S58...

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báo cáo hóa học: " Quality of life in Croatian Homeland war (19911995) veterans who suffer from post-traumatic stress disorder and chronic pain" doc

Ngày tải lên : 20/06/2014, 15:20

... 0. 68 9 < 0. 0 01 1 . 16 [0. 56 -2. 41] 0. 39 [0. 24 -0. 64 ] 0. 3 51 0. 0 60 1. 42 [0. 68 -2. 98] 0. 62 [0. 37 -1. 04 ] 0. 29 8 0. 0 01 1. 42 [0. 73 -2. 77] 0. 46 [0. 28 -0. 73] Physical 0. 9 16 1. 00 [0. 95 -1. 06 ] 0. 9 76 1. 00 [0. 95 -1. 06 ] ... 0. 01 5 2. 57 [1. 20 - 5. 52] 0. 0 01 3.43 [1. 61 - 7. 32] 0. 484 < 0. 0 01 0. 32 [0 .17 -0. 60 ] 0 .00 5 0 . 40 [0. 21 - 0. 76] 0. 057 0. 59 [0. 35 -1. 01 ] 0 .15 2 1. 62 [0. 84-3 .15 ] 0. 01 7 2. 21 [1. 15-4 .24 ] 0. 724 0. 88 [0. 45 -1. 75] 0. 68 9 ... Environmental 0 .00 6 0. 95 [0. 91- 0. 98] 0 .11 5 0. 97 [0. 93 -1. 01 ] 0. 049 0. 96 [0. 92 -1. 00 ] < 0. 0 01 0 .15 [0. 05 -0. 39] 0. 01 0 0 .14 [0. 03 -0. 62 ] 0. 058 0. 45 [0 .18 -1. 03 ] Marital status Smoking Education Pysical activity...

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Stress, Strain, and Structural Dynamics ppt

Ngày tải lên : 29/06/2014, 09:20

... Quick Solution Guide 14 .6 References 66 7 66 7 6 70 6 70 67 5 68 3 68 7 68 9 6 91 6 91 6 92 69 6 69 8 707 7 12 715 715 7 21 729 7 36 Two-Dimensional Elastic Continua ;er Static Analysis of Linearly Elastic Bodies ... 6. 3.5 Total Response 6. 3 .6 Influence Lines 6. 4 The Distributed Transfer Function Method 15 7 15 9 15 9 16 1 16 6 16 6 17 1 17 6 17 8 18 1 18 3 18 9 6. 5 6. 6 Quick Solution Guide References 20 0 Chapter Static ... displacement = 0 .00 0 46 807 , location x = rotation (degrees) = 0. 0 20 21 3 , location x = 0. 52 bending moment = 1. 2 405 , location x = shear force = -3 .00 7 6, location x = x io' displacement, w(x) x ig'4...

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Tài liệu tiếng anh tham khảo stress coping and health

Ngày tải lên : 09/07/2014, 08:25

... blaming, minimizing, wishful thinking, venting emotions, seeking social support, exercising, and meditating Similar to the cognitive strategies identified in problemfocused coping efforts, changing how ... Medicine, 325 , 60 6 – 6 12 Cox, D M., & Gonder-Frederick, L (19 92) Major developments in behavioral diabetes research Journal of Consulting and Clinical Psychology, 60 , 62 8 63 8 Crofford, L J., Jacobson, ... ( 20 0 8 ) Stress-induced physiologic changes as a basis for the biopsychosocial model of chronic musculoskeletal pain: A new theory? Clinical Journal of Pain, 24 (9), 767 –775 Fitzgerald, P J ( 20 0 9 )...

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Devaluation and the trade balance

Ngày tải lên : 23/07/2014, 16:28

... Balance Balance Ratio Before devaluation in both domestic and foreign currency After devaluation in foreign currency After devaluation in domestic currency 15 0 IOO 12 0 80 18 0 12 0 50 so 67 40 67 60 ... URL: http://links.jstor.org/sici?sici =0 01 3 -04 27 %2 819 3 911 %29 2%3A6%3A24% 3C3 75%3ATTOFE%3E2 .0. CO%3B2-R NOTE: The reference numbering from the original has been maintained in this citation list ... URL: http://links.jstor.org/sici?sici =00 3 0- 765 3 %2 819 4 20 4 %2 91% 3A0%3A6% 3C5 7%3ATBAES%3E2 .0. CO%3B2-S The Theory of Foreign Exchanges F Machlup Economica, New Series, Vol 6, No 24 (Nov., 19 39), pp 375-397...

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Báo cáo sinh học: " Genome degeneration affects both extracellular and intracellular bacterial endosymbionts" pot

Ngày tải lên : 06/08/2014, 19:20

... D: Candicidin-producing Streptomyces support leaf-cutting ants to protect their fungus garden against the pathogenic fungus Escovopsis Proc Natl Acad Sci USA 20 0 9 , doi : 10 . 10 73_pnas .0 8 12 08 2 10 6 ... Stinkbugs Human Tsetse flies Mammalian intestine Free-living Genome size (kbp) 705 -7 92 8 20 - 8 30 900 - 9 60 1, 04 3 4 ,17 0 4 ,63 9 (9 72 pseudogenes)† 13 ,03 4 GC content (%) 27 .4 -29 .6 38.9 (groEL)§ 36- 38 (groEL)§ ... mutualistic mutualistic Host Psyllids Sharpshooters Aphids Human Cockroaches Sharpshooters Tsetse flies Genome size (kbp) 16 0 24 5 422 -68 6 5 80 Approximately 6 50 68 6 69 8 GC content (%) 16 .5 22 .4 20 .1- 26 .2...

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Báo cáo sinh học: " Oxidative stress, thermogenesis and evolution of uncoupling proteins" doc

Ngày tải lên : 06/08/2014, 19:20

... http://jbiol.com/content/8 /6/ 58 Journal of Biology 20 0 9 , Acknowledgements We acknowledge the support from the Spanish Ministry of Science and Innovation to ER (BFU 20 0 6 -0 818 2 and Consolider-Ingenio 2 01 0 CSD 20 0 7 -00 0 20 ) ... 58.3 UCP2 UCP1 UCP3 Plant UCP UCP4 UCP2 80 99 UCP5 DIC 55 86 OGC 75 57 ANT 88 69 PiC 99 0 .1 50 UCP3 87 50 92 77 97 68 86 UCP1 99 UCP Sea urchin 89 92 75 UCP4 78 76 0. 4 Eutherian mammals 67 92 83 ... rounds of gene duplication [7,8 , 10 ] The ancestor of vertebrate UCP1-3 first duplicated into UCP1 and the common ancestor of UCP2-3, which subsequently duplicated into UCP2 and UCP3 Each of the three...

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