1€ creating a core data model with xcode

... in our database In Recipe 13.1, you will learn how to create a Core Data model using Xcode This is the first step toward creating a database schema 13.1 Creating a Core Data Model with Xcode Problem ... xcdatamodel in your application bundle in Xcode and click on it to open the visual data editor, as shown in Figure 13-4 13.1 Creating a Core Data Model with Xcode | 653 Figure 13-4 Visual data ... responsible for managing different object contexts 652 | Chapter 13: Core Data Managed object model This is the same concept as a schema in a database This could represent the tables in a database or the...

Ngày tải lên: 13/08/2014, 18:20

... Programmatically adding an event to a calendar iOS syncs online calendars with the iOS calendar These calendars could be Exchange, CalDAV, and other common formats Creating an event on a CalDAV calendar ... Calendars | 707 } NSArray *calendars = [[NSArray alloc] initWithObjects:targetCalendar, nil]; NSPredicate *predicate = [eventStore predicateForEventsWithStartDate:paramStartDate endDate:paramEndDate ... createEventWithTitle:@"Shopping" startDate:startDate 708 | Chapter 14: Dates, Calendars and Events endDate:endDate inCalendarWithTitle:@"vandad.np@gmail.com" inCalendarWithType:EKCalendarTypeCalDAV notes:@"Get bread"]; if...

Ngày tải lên: 13/08/2014, 18:20

... plasmid expressing GFP-Mls1p This This [5] This [22] [21] This study 5¢-CACTGATTTGTGAGAATTCTGATCTCC-3¢ 5¢-CAATGAACTCTAGAGC-3¢ 5¢-GATACTAAGTGAGCTTAAGGAGG-3¢ 5¢-CCCGACGCCGGACGAGCCCGC-3¢ 5¢-AGAAAGATCTATCTAGTGGGTTGAATTGCGGACGTTGG-3¢ ... probed with anti-malate synthase (a- Mls1p) or anti-catalase A (a- Cta1p) Ig Molecular mass markers (kDa) are indicated to the left 920 M Kunze et al (Eur J Biochem 269) Ó FEBS 2002 advantage to ... 5¢-AGAAAGATCTATCTAGTGGGTTGAATTGCGGACGTTGG-3¢ 5¢-AGAAGCATGCGATCACAATTTGCTCAAATCAGTGGGCGTCGCC-3¢ This This This This This This study study study study study study to dilution to pH 7.0 with NaOH) The...

Ngày tải lên: 22/02/2014, 04:20

... shown Black geometrical shapes are additional domains, as indicated ANOGA, Anopheles gambiae; ASHGOS, Ashbya gossypii; BRARE, Brachydanio rerio; CANDGLA, Candida glabrata; CIONA, Ciona intestinalis; ... DL, Jacobsen BM, Flodin A & Skalnik DG (2000) Cloning of a mammalian transcriptional activator that binds unmethylated CpG motifs and shares a CXXC domain with DNA methyltransferase, human trithorax, ... that DIDO-related apoptosis occurs as a result of alterations in DNA regulation caused by chromatin instability Computational analyses Although all splice variants share common domains, long regions...

Ngày tải lên: 07/03/2014, 21:20

... 32 Lan L, Nakajima S, Oohata Y, Takao M, Okano S, Masutani M, Wilson SH & Yasui A (2004) In situ analysis of repair processes for oxidative DNA damage in mammalian cells Proc Natl Acad Sci USA ... single-strand break repair J L Parsons et al References Caldecott KW (2001) Mammalian DNA single-strand break repair: an X-ra(y)ted affair Bioessays 23, 447– 455 Wallace SS (1988) Detection and repair ... Removal by human apurinic ⁄ apyrimidinic endonuclease (Ape 1) and Escherichia coli exonuclease III of 3¢-phosphoglycolates from DNA treated with neocarzinostatin, calicheamicin, and gammaradiation...

Ngày tải lên: 23/03/2014, 11:20

... Laticauda semifasciata III, a weak and reversibly acting neurotoxin from venom of a sea snake, Laticauda semifasciata Biochem J 141, 389–400 37 Scarselli, M., Spiga, O., Ciutti, A. , Bernini, A. , ... Naja naja neurotoxin and preparation of radioactive derivatives Biochem Biophys Acta 257, 235–248 36 Maeda, N & Tamiya, N (1974) Isolation, properties and amino acid sequences of the toxin Laticauda ... mutational analysis of a- cobratoxin (a- CTX) indicate that replacement of at least eight residues (Arg33, Lys49, Asp27, Lys23, Phe29, Trp25, Arg36 and Phe65) to unrelated ones causes a remarkable...

Ngày tải lên: 23/03/2014, 13:20

... in healthy volunteers Microbial vectors Vaccinia (NYVAC) – HIV Adenovirus expressing PSMA Vaccinia (MVA) – melanoma epitopes Vaccinia (MVA) – malaria TRAP Increased cellular immunity in healthy ... protective capability in several animal models With the advent of other vectors such as DNA vaccines, and a range of recombinant microbial vectors including alpha virus replicons, research in the area ... Biswas S, Reddy GS, Srinivasan VA, Rangarajan PN: Preexposure efficacy of a novel combination DNA and inactivated rabies virus vaccine Hum Gene Ther 2001, 12:1917-1922 32 Wang S, Parker C, Taaffe...

Ngày tải lên: 18/06/2014, 16:20

... people  Changing expectations Approach for Business Today  Various Descriptors • Strategic Alliances/Partnerships • Relationship Marketing  Characterized by: • Closer and more integrated ties ... connotes the active nature of negotiation begun with an invitation made by interdependent parties to grapple with shared concerns Characteristics of a Skilled Negotiator  Mindfulness – alert to ... Involve individuals or groups  Is pervasive throughout one’s life Focus of Text  How successful negotiation alliances are formed  Emphasizes language and the talk of negotiation  Engagement connotes...

Ngày tải lên: 31/07/2014, 17:20

... spectrophotometrically High-quality RNA for use in the microarray analysis was confirmed by analysis in the Agilent 2100 Bioanalyzer (Agilent Technologies, Palo Alto, CA, USA) Microarray analysis Total mRNA ... RNA isolation Total RNA was isolated from cultures by Trizol (Invitrogen) followed by RNeasy clean-up (Qiagen, Mississauga, ON, Canada) as per the manufacturer's directions Total RNA was quantified ... proteins that localized to the extracellular space and had collagenase or hyaluronic acid binding activities We determined that specific matrix metalloproteinases and cartilage-selective ECM transcript...

Ngày tải lên: 09/08/2014, 01:22

... GTG GAC 3' 5' CGA CGT CAT CTC CAA CAT CGA GAC 3' 5' GTT GGG CGG CAG GTA CTG 3' 0.0562 SOX6 5' CCG TGA GAT AAT GAC CAG TGT TAC TT 3' 5' AAC CCC AGA GCG CCG CAA A 3' 5' GTC CAC CAC ATC GGC AAG AC ... TTA GCA GGT AGC GCT TT 3' 0.052 ADAMTS-5 5' GGA CCT ACC ACG AAA GCA GAT C 5' CCC AGG ACA GAC CTA CGA TGC 3' CAC C 3' 5' GCC GGG ACA CAC GGA GTA 3' 0.122 0.047 ADAMTS, a disintegrin and metalloproteinase ... CCA AAG GCT ACA A 3' 5' CTC CAA GGA CCC TGG AGC ACT CAT GTT 3' 5' CTT TTG CCG GTG TAG GTG TAG ATA G 3' 0.108 ADAMTS-4 5' ACT GGT GGT GGC AGA TGA CA 3' 5' ATG GCC GCA TTC CAC GGT G 3' 5' TCA CTG...

Ngày tải lên: 09/08/2014, 06:22

... fw:CTATGGAGGCCAGAAGAGGGTAT rv: CACACCATCTTCTGGTGTACAGTCT AGATCCCTTGAAGCTAG-MGB rv:CCCACATCAGGTGGCTCATAA Glucose transporter-1 fw:GGGCATGTGCTTCCAGTATGT CAACTGTGCGGCCCCTACGTCTTC rv:ACGAGGAGCACCGTGAAGAT fw, ... that HIF-1α has an important role in the survival of tissues that lack a functional vasculature, such as articular cartilage Articular cartilage adapts to hypoxic conditions, since the cartilage ... HIF-1α mRNA in the articular cartilage from patients with osteoarthritis (OA) (a) Representative x-ray film of knee joint and safranin-O stainthe articular cartilage from patients with osteoarthritis...

Ngày tải lên: 09/08/2014, 06:23

... using random hexamer primers (Pharmacia, Woerden, The Netherlands) and reverse transcriptase (Pharmacia) For reverse transcription PCR, human Cyp7b sense (GTCCTGGAGAAATATTATGTGCAG) and antisense ... (CGCACACAGTAGTCCCCGG) primers were used For GAPDH we used CCCTTCATTGACCTCAACTACATGG (sense) and GGTCCACCACCCTGTTGCTGTAGCC (antisense) as primers Reverse transcription PCR was carried out using an ... Haas M, Page S, Page M, Neumann FJ, Marx N, Adam M, ZieglarHeitbrock HW, Neumeier D, Brand K: Effect of proteasome inhibitors on monocytic IkappaB-alpha and -beta depletion, NF-kappaB activation,...

Ngày tải lên: 09/08/2014, 07:20

Ngày tải lên: 09/08/2014, 07:20

... clinical decision making? Scand J Trauma Resusc Emerg Med 2010, 18:34 Aller MA, Arias JI, Alonso-Poza A, Arias J: A review of metabolic staging in severely injured patients Scand J Trauma Resusc ... extracellular form it can bind to an inflammatory receptor called Receptor for Advanced Glycan Endproducts (RAGE) Activated macrophages and monocytes secrete HMGB1 as a cytokine in inflammation ... The diagnostic value of HMGB1 levels was investigated using ROC curve analysis in this study by Albayrak et al [5] The use of ROC analysis is an Page of appropriate method in evaluation for various...

Ngày tải lên: 13/08/2014, 23:20

... Georgia Papageorgiou and Anna Sidera for their continual support and the great summers I spent with them I thank my grandparents Panagiota and Charalambos Konstantinou, Maria Zeniou and my spiritual ... than a family to me here in Tucson: Nakul Chitnis; Luis Garcia-Naranjo; Adam Spiegler; Rosangela Sviercoski; Gabriella, Eleni, Alexandros and Pavlos Michaelidou; Antonio Colangelo and Mariagrazia ... complicated: First notice that az + b az + a 1 z −1 b = ¯ +a −1 bz a ¯ bz ¯ a ¯ + and recall that a = eπiA and that z = e2πit Let w = a 1 z −1 b Then, the above equation can be written as: 1+w az...

Ngày tải lên: 13/11/2014, 09:14

... support I would also like to thank Mr J Manikandan for all his invaluable help with microarray analysis Heartfelt thanks to Mr Ganesan Arasapam for his efforts in PCRarray and Ms Cynthia and Mr Ghee ... International Drug Discovery Science and Technology, Shanghai, China • Balakrishnan L, Poonepalli A, Low GKM, Newman, JP, Kashimshetty R, Khaw AK, Bhattacharjee RN, Akira S, Jayapal M, Balajee AS, Hande ... Meeting of IADR Pan Asian Pacific Federation (PAPF) and the 1st Meeting of IADR Asia/Pacific Region (APR), Wuhan, China • Balakrishnan L, Jayapal M, Hande MP (2009) DNA repair deficiency and Telomere...

Ngày tải lên: 11/09/2015, 10:18

... 5’ AAC TTT GGC ATT GTG GAA GG- 3’ 5’ ACA CAT TGG GGG TAG GAA CA- 3’ Table 5: Antibodies used for western blotting and confocal microscopy Anibody AlexaFluor 488 antirabbit IgG Goat polyclonal ... kinase (IRAK) followed by the association with tumor necrosis factor receptor activated factor-6 (TRAF6), eventually leading to the activation of JNK and NFkB signaling pathways (Takeda and Akira, ... of ANXA1 to the cell surface, due to its association with caspase-3 activation (Arur et al., 2003; Debret et al., 2003) This indicates a role for ANXA1 in apoptosis 1.6.1.3 ANXA1 in cancer ANX1...

Ngày tải lên: 01/10/2015, 17:27

... GACCT 3’ 5’CTCTACTCCAAGGGCT S1P4 ATGT 3’ 5’GTGTGTGCCTTCATTG S1P5 TG 3’ Antisense CGGACTCCGCAAAGTCTAAG Size (bp) 205 AGGCCACAGGTATTTTGTCG 229 CTCACTGGGACAGCACAGAA 217 GGATGCCACAGGATTCCATAC CCA ... CCA GGAAAGCAACCACGGGCACA 314 507 5’GCTTCGAGTCCTGACCCA 3’ 5’GGCCACTTGTCTCTCGAT 3’ 5’ACTGTTGGAGACAGACTGAA CG 3’ 5’ TGGAGACTTCTGCCCATT 3’ 5’CAGGTCCGACAAAGTGAG 3’ 29 80120 2.5 µl of cDNA was used ... suggest that the activation of pro-inflammatory factors such as TNF-α can participate in causation of neuronal death (Harry and Kraft, 2008, Harry, et al., 2008, Kaushal and Schlichter, 2008) In adddtion,...

Ngày tải lên: 16/10/2015, 15:38

... management of spending & saving money D) Progress report: Regular progress reports should be prepared and should outline: • Decisions reached and make by the project team • Activities and tasks ... provide an overview of the allocation of funds or the estimation of cost for the project (salaries, outsourcing costs, research fees, use of materials, hire of equipment and administrative support) ... and tasks accomplished • Milestones reached • Work still to be done • Any issues or problems that have arisen and need to be addressed Progress reports are useful for explaining the status of the...

Ngày tải lên: 24/04/2016, 12:10