... consequence of the work of Heilmann and Lieb [8], while the second is due to Joni and Rota [9] Theorem For any R ∈ L(k, n) where k ≥ 2, the roots of ρ G(R), x are real and lie in the open interval ... two paths they correspond to, one is a maximal proper subpath of the other The root of T (R, v) is the vertex corresponding to the empty path Let ηv,r be the number of closed walks of length ... number of perfect matchings in an (n − k)-regular subgraph of Kn,n The other incarnation of the problem is in (0, 1)-matrices Let Λk denote the set of n (0, 1)-matrices of order n in which the...
Ngày tải lên: 07/08/2014, 06:22
... As wife, mother, and best friend, she is the "real leader" of the McHugh clan and, like all the recognized and unrecognized "real leaders" everywhere, makes good things happen each and every day ... or other expert assistance is required, the services of a competent professional person should be sought Library of Congress Cataloging-in-Publication Data McHugh, Donald E Golf and the game of ... Fellow golfers and friends—Ken Smith, Bob Lauer, and the rest of the ‘‘Tuesday Group’’—were much-appreciated cheerleaders from the first tee to the last Christine Brennan, noted author and sports...
Ngày tải lên: 24/12/2013, 16:15
Tài liệu Báo cáo khoa học: Mutational analysis of plasminogen activator inhibitor-1 Interactions of a-helix F and its neighbouring structural elements regulates the activity and the rate of latency transition pdf
... 5), and the salt-bridge between E132 and R135 [18] contribute to the thermodynamic stability of the stressed conformation and/ or are important for the positioning of hF in a way delaying the ... mimicking the effect of the K325A substitution (Fig 5) Of note is that the side chain of E285 forms a hydrogen bond to the backbone of the hF/s3A-loop in PAI-1stab [18] (Fig 5) and in contrast with the ... stabilize the stressed conformation of these serpins by relieving the strain of side chain overpacking between the K325 side chain and residues in the hF/s3A-loop, i.e the conserved I150 and L153...
Ngày tải lên: 20/02/2014, 11:20
Báo cáo khoa học: Interaction between Lim15/Dmc1 and the homologue of the large subunit of CAF-1 – a molecular link between recombination and chromatin assembly during meiosis pot
... double-strand breaks (DSBs) A single-strand overhang is formed by exonuclease activity and invades the homologous doublestranded region of the other allele These steps of homology search and recombination ... [8] The heterodimeric complex of Hop2 and Mnd1 stimulates strand exchange of Lim15/Dmc1 [9–11] The meiosis-specific proteins Mei5 and Sae3 form a complex with Lim15/Dmc1 and are necessary for the ... cloning of CcCac1L and its interaction with CcLim15 (A) Schematic diagram of the CAF-1 large subunits in human, C cinerea and S cerevisiae The KER and ED domains are represented by black and grey...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Metabolomics, modelling and machine learning in systems biology – towards an understanding of the languages of cells potx
... between the worlds of ideas and of experimental data The world of ideas includes theories, hypotheses, human knowledge and any other mental constructs, while the world of data consists of experimental ... Most of these have yet to be identied chemically The history of biomedicine as perceived via the awards of the Nobel Committee indicates the importance to our understanding of the subject of both ... describes the networks structure, and has nothing to with structural biology) that denes the participants in the process of interest and the (qualitative) nature of the interactions between them; then...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Carbohydrate binding sites in Candida albicans exo-b-1,3-glucanase and the role of the Phe-Phe ‘clamp’ at the active site entrance ppt
... seen for the Phe triad in the structure of the mutant Exg:L3 complex Neither of the two sugar residues interacting with the Trp triad overlaps with the sugar seen in the Phe-Phe clamp of Exg Structural ... Rearrangement of the water molecules in and around the clamp region as seen in the crystal structure may be relevant The relative activities of the mutants tested showed the same trend for both the hydrolysis ... solved the crystal structure of this GH5 enzyme in the presence of two different mechanismbased inhibitors, thereby revealing the close network of interactions that hold the terminal glucose of the...
Ngày tải lên: 15/03/2014, 23:20
beyond babel - a handbook of biblical hebrew and related languages
... existence in the corpus of diverse dialects in addition to the standard Jerusalem literary dialect in which most of the text was written The study of other languages and of other forms of Hebrew ... the exaltation of Yahweh in the Song of the Sea (Exod 15) and the subsequent erection of the tabernacle in the wilderness.20 2.2.2 THE FLOOD STORY As noted earlier, it was the comparison of the ... Three other celebrated comparisons between Mesopotamian annals and the biblical record are the accounts of the fall of Samaria, the siege of Jerusalem, and the fall of Jerusalem The fall of Samaria...
Ngày tải lên: 17/04/2014, 09:45
introduction to languages and the theory of computation
... abab}, and {aa, ab, aab, ba, bb, bab} The first of these is the union of {a} and {b}, the second is the concatenation of {a} and {b}, the third is the union of the first and second, the fourth is the ... (n) is the set of prime factors of n e (Here A is the set of all finite sets of primes and B is the set N − {0}.) g : A → B, where g(S) is the product of the elements of S (The product of the elements ... close resemblance of the statements 1–3 to the recursive definition of Expr The outline of the proof is provided by the structure of the definition We illustrate the technique of structural induction...
Ngày tải lên: 31/05/2014, 00:58
Báo cáo hóa học: " A predominance of R5-like HIV genotypes in vaginal secretions is associated with elevated plasma HIV-1 RNA levels and the absence of anti-retroviral therapy" docx
... analysis, and drafted the manuscript PK participated in the study design and conducted the statistical analyses RC participated in the design and coordination of the study and facilitated the collection ... [9,13], the low levels of HIV detected in many of the samples only allowed the analysis of the predominant genotypes in genital secretions Despite this, and the inherent limitations of PCR amplification ... collection of clinical samples NL processed clinical samples and conducted PCR and viral load analyses AA participated in the coordination of the study, directed sample and data analysis, and assisted...
Ngày tải lên: 20/06/2014, 01:20
Journal of retailing and consumer services volume 19 issue 1 2012 modeling the effect of self efficacy on game usage and purchase behavior
... present the conceptual model which begins with a definition of the concept of the game leading to our hypotheses The paper follows with the methodology and results The paper concludes with the discussion, ... Simulation and Driving; (3) RPG, MMORPG and Strategy and (4) Action, Adventure and Fighting As we have noted in our hypotheses; these hypotheses are extended over the game types so the analysis of the ... Bollen–Stine (B–S) p value The SEM focused on the analysis of the hypotheses of the four competing forms of this model; (1) the original model includes all the game types while the alternative models...
Ngày tải lên: 23/06/2014, 15:22
Imperialism, Sovereignty and the Making of International Law Part 1 pdf
... colonial problems The Mandate System and the construction of the non-European state Government, sovereignty and economy The mandate and the dissolution of sovereignty The legacies of the Mandate System: ... System of the League of Nations Introduction The creation of the Mandate System 115 115 119 vii 32 32 40 52 viii contents The League of Nations and the new international law The Mandate System and ... Commission of Inquiry and gave it the task of examining the legal, historical and scientific aspects of the phosphate industry, and the feasibility of rehabilitating the worked-out phosphate lands Acting...
Ngày tải lên: 05/08/2014, 22:20
European Conquest and the Rights of Indigenous Peoples Part 1 doc
... peoples of West Papua; the Naga and others in India; the Karen and Kachin in Myanmar; the Ainu of Japan; the Hmong peoples of Thailand and Vietnam; the Aborigines and Torres Strait Islanders of Australia; ... parts of Norway, Sweden, Finland and Russia; the Chittagong Hill Tract Peoples, which includes the Chakma, Marma and Tripurs; the Kalinga and others in the Philippines; the Mae-Enga, Dani and Tsembaga ... formation and largely excluded from the full rights enjoyed by citizens of the states that are the members of international society Understanding the reasons for this exclusion and how the rights of...
Ngày tải lên: 09/08/2014, 11:20
Báo cáo y học: "Protein Never in Mitosis Gene A Interacting-1 regulates calpain activity and the degradation of cyclooxygenase-2 in endothelial cells" pot
... prostaglandin synthesis [40], and S-nitrosylation of COX-2 activates the enzyme and contributes to cell injury [41,42] The impact of the co-induction of iNOS and COX-2 in endothelium requires further ... affect the expression or activity of calpain subunits, and the endogenous inhibitor of heterodimeric calpains, calpastatin [39] The effects of COX-2 in acute and chronic inflammatory responses in the ... prostaglandin receptors [16] Here, depletion of PIN1 and inhibition of calpain each caused overinduction of both COX-2 and iNOS The consequences of co-induction of these two particular enzymes may be...
Ngày tải lên: 11/08/2014, 08:22
Báo cáo y học: "Egress of HSV-1 capsid requires the interaction of VP26 and a cellular tetraspanin membrane protein" doc
... viral envelope and the exterior membrane facilitates egress of the enveloped virion from the nucleus via the cis-network and remains in the cisterna of perinuclear space The virion is then transported ... of 12 Figure CTMP-7 is a VP26 interacting protein a Binding assay of the proteins and VP26 The positive control was the fusion yeast containing pGBK-p53 and pACT-LT The negative control was the ... in the cytoplasmic membrane We hypothesized that the effect of decreased CTMP-7 levels on viral replication most likely takes place during the egress of HSV-1 particles Therefore, the egress of...
Ngày tải lên: 12/08/2014, 04:20
Báo cáo y học: " Peptides derived from the HIV-1 integrase promote HIV-1 infection and multi-integration of viral cDNA in LEDGF/p75-knockdown cells" doc
... particularly the absence of any cDNA integration events in such cells is due to the inhibitory effect of Rev [4,6,10,11] Due to the absence of the LEDGF/p75 protein in these cells, all of the IN molecules ... first-round PCR, the LTR-Tag-F and LTR-R primers were used and the second-round PCR was performed using the Tag-F and LTR-R primers The standard linear curve was in the range of ng to 0.25 fg ... promote dissociation of the Rev-IN complex [17,22,24] Therefore, in light of the above results, it was of interest to find out whether the INrs would also stimulate integration of viral cDNA in LEDGF/p75-knockdown...
Ngày tải lên: 12/08/2014, 04:20
Teaching About Evolution and the Nature of Science - NAP (2004) Episode 1 ppsx
... three of the most fundamental features of the world around us: the similarities among living things, the diversity of life, and many features of the physical world we inhabit Explanations of these ... group of 1,800 scientists dedicated to the use of science and technology for the general welfare The Academy and its affiliated institutions— the National Academy of Engineering, the Institute of ... use to inform themselves, their students, parents, and others about evolution and the role of science in human affairs One source of resistance to the teaching of evolution is the belief that...
Ngày tải lên: 12/08/2014, 08:21
Báo cáo y học: " Live cell visualization of the interactions between HIV-1 Gag and the cellular RNA-binding protein Staufen1" pot
... subsequently fixed, and immunofluorescence was performed to obtain snapshots of the distributions of Gag and of the raft marker protein, Caveolin-1 (Figure 4B) Indeed, both Caveolin-1 and Gag staining ... complementation of both VN and VC fragments the simultaneous expression of three plasmids is required In the first case the VN is expressed as a fusion MS2-VN protein and can tether to the RNA reporter ... concomitantly, via the same protein domain (NC), reveals a rather multifaceted property of Gag and further strengthens the implication of Staufen1 in HIV-1 assembly [21] Furthermore, time-lapse...
Ngày tải lên: 12/08/2014, 23:23
Báo cáo y học: " The role of the N-terminal segment of CCR5 in HIV-1 Env-mediated membrane fusion and the mechanism of virus adaptation to CCR5 lacking this segment" ppt
... It is thought that the stem of the V3-loop and the bridging sheet of gp120 bind to the Nt of CCR5, whereas the tip of the protruding V3loop interacts with other determinants of CCR5, most likely ... gp120-CD4 binding and is comprised of conserved residues from the C4 domain and from the stems of variable V1/V2 and V3 loops [8,23-28] The tip (often referred to as crown) of the V3-loop appears ... allow Env(NYP) to induce fusion in the presence of Sch-C On the other hand, the marginal increase in the resistance to Sch-C (Fig 3) and the accelerated kinetics of fusion (Fig 1B) from 27°-TAS,...
Ngày tải lên: 13/08/2014, 05:22
homomorphisms of the fundamental group of a surface into psu(1,1), and the action of the mapping class group
... to be crucial for the proof of the ergodicity of the mapping class group In section 6.3 we state the main theorem of this paper To proceed the proof of the theorem we state and prove two key ... ]} The level sets of R1 are connected ±1 {U0 } R1 (Ell × Ell) = R1 (G \ Hyp) × G ∪ G × (G \ Hyp) = {ρ = 0} We present the proof of the first and the third part of this proposition The proof of ... conj denote the projection The idea of the proof is to prove first that the space of conjugacy classes of Im(Rp−1 ) ∩ gc Im(R1 ) is connected, then use the fact that each ˜ one of the conjugacy...
Ngày tải lên: 13/11/2014, 09:14
Vascularised bone tissue engineering endothelial progenitor cells and human mesenchymal stem cells coculture in 3d honeycomb scaffolds and the effect of bi rotational bioreactor and hypoxic microenvironment 1
... supervisors Prof Teoh Swee-Hin and A/Prof Jerry Chan I would like to thank them for their constant sharing of knowledge and ideas, their patience and understanding, and the many hours they have each ... is often neglected, likely to be essential for the maturation and long term efficacy of these bone grafts upon clinical translation 13 There is also a lack of understanding on the importance of ... region of the epiphysis and metaphysic (Eriksen et al 1994; Deng and Liu 2005; Gruber 2008) The periosteum surrounds the outside of bone except at areas covered by the articulating cartilage, and the...
Ngày tải lên: 09/09/2015, 10:16