1—build the topology depicted in figure 5 28

... =E0.07 K, in good agreement with the measured value The emission from the ground and from the Sun was minimized by the design of the antenna and by shielding the instrument with large aluminum reflectors, ... energy injected in the radiation field (ei being the radiation energy density before the heating) The above formulae are a rather accurate description of numerical calculations, in the hypothesis ... Ae/e) includes the effect of relativistic neutrinos on the expansion time in presence of energy injected in the radiation field (for species of massless neutrinos, ~ = 1.68) On the other hand the...

Ngày tải lên: 03/07/2014, 21:10

... during the 2011 flood The network remains intact today, and springs into motion during the wet season in preparation for possible floods Springer et al (2012) further suggest that the unfolding ... waiting for flood initiatives from the local and central governments Furthermore, they are also not waiting for the next big flood; instead, they are anticipating the fluxes in the riverine rhythms ... acknowledging the limits to their capacities to act in the world They recognize that their capacities to act with (in) the world in becoming is relational to the actions of others By acknowledging this...

Ngày tải lên: 22/09/2015, 15:19

... containing the QTL in the distal part of BTA5 and were used in the present study We performed SNP genotyping in two stages First, 75 animals i.e the gransires of the nine initial GD families and their ... option of the CRI-MAP program The resulting final map (Table 1) was used for all the following analyses QTL fine mapping LDL mapping by microsatellite markers Joint linkage disequilibrium and linkage ... linkagedisequilibrium (LD) information increases the precision of QTL mapping because it exploits the entire number of recombinations accumulated since the original mutation generating the new QTL allele...

Ngày tải lên: 14/08/2014, 13:21

... ‘below’ the Q119 guanidiniums of the four domains, holding the domains together and blocking the channel Adding charges (one proton per domain) breaks the plug, the side chains separate, and the ... mediates the suppression of the brain in ammation in the LPSinduced experimental brain in ammation model in vivo PP-27 Transglutaminase inhibition promotes sensitivity to the chemotherapy in cancer ... Consequently, the involvement of clathrin in albumin uptake by astrocytes is also being investigated In brief, we describe for the first time the mechanism of albumin uptake in astrocytes, which is the initial...

Ngày tải lên: 19/02/2014, 07:20

... complexes are absent in the lanes containing the probe with the 1G SNP Although increasing concentrations of PD098059 reduce the binding of complexes to the probe containing the 1G SNP, a more pronounced ... containing the 1G probe appear unchanged in the presence of the inhibitor (–) Thus, a decrease in the expression of MMP-1 in the presence of PD098059 may be due, at least in part, to a decrease in ... expression from the 1G promoter in the presence of increasing amounts of Fra1 may be due to the effects of Fra-1 on the proximal AP-1 site The greater increase in the induction of the 2G promoter...

Ngày tải lên: 21/02/2014, 00:20

... designs In order to get you thinking in the terminology of the iOS SDK, I’m going to refer to each of the screens in our app as views I’ll go further into the details of views and view controllers in ... featured by Apple in the App Store  They’ve got lots of 4- and 5-star ratings  They had the idea first and launched ahead of the competition The last point in this list is often one of the most likely ... Help Click the links to access the full documentation Info.plist Select and view BirthdayReminder-Info.plist You’ll find this important file within the Supporting Files group This is the configuration...

Ngày tải lên: 06/03/2014, 03:20

... new exon originating from the non-coding sequences of intron of the SAF-1/MAZ gene resulted in creation of a different C-terminus consisting of eight zinc finger domains in SAF-2 [23] The SAF-2 isoform ... of the first exon of human SAF-1/MAZ (Fig 2A) The first exon in human SAF-3 (exon 1A) encodes 12 amino acids, including the initiator methionine (Fig 2B) The nucleotide sequence around the initiation ... (b) binding of the N-terminus by ancillary factors, (c) the lack of a negatively functioning module that is present in the N-terminus of SAF-1 [26], or (d) all of the above It was interesting...

Ngày tải lên: 07/03/2014, 02:20

... administered to establish the role of protein synthesis in insulin-induced HO-1 expression (Fig 2B,C) CHX abrogated HO-1 protein induction following insulin treatment but, in agreement with other ... oxidative insult Insulin is a polypeptide hormone that regulates glucose, lipid and protein metabolism and promotes cell growth and differentiation On ligand binding, the insulin receptor tyrosine kinase ... treated in a similar manner with insulin (200 nm) for increasing periods of time (Fig 1E) A robust induction of HO-1 protein was observed Insulin-mediated induction of HO-1 is PI3K dependent In our...

Ngày tải lên: 07/03/2014, 12:20

... other features contribute to raptor binding We have not therefore attempted to define further the features in the C-terminus of 4E-BP1 that are involved in its binding to raptor The data for the ... mutating the proline to alanine (to give the RAIA mutant) causes a defect in the basal and insulin-stimulated phosphorylation of 4E-BP1 [25] We also tested the proline to valine mutation in wild-type ... positions (phenylalanine or leucine in the first position, and methionine, isoleucine or probably similar residues in the third) The requirements at the other positions are less strict: in the second and...

Ngày tải lên: 16/03/2014, 06:20

... domain ERM contains two DNA binding inhibitory domains flanking the Ets domain: the central 87 amino acid inhibitory domain is poorly conserved and virtually specific to ERM, and the C-terminal ... complexes (B) The binding of in vitro translated ERM is eliminated by mutations in Ets motifs The binding of in vitro translated ERM over the PS1 promoter was assayed by EMSAs including the 32P-labeled ... flanking the +1 site (A) The binding of nuclear factors is eliminated by mutations in Ets motifs The binding of nuclear factors present in SK-N-SH (K) or SH-SY5Y (H) nuclear extracts over the...

Ngày tải lên: 16/03/2014, 18:20

... distributed in the posterior hindbrain and anterior spinal cord in which the signal was restricted to the dorsal spinal cord and gradually diminished along the length of the spinal cord (Fig 5B,F) The ... showed that there is a proline insertion in the amino acid sequence immediately following the initiator methionine (Fig 1A) Sequenced genomic DNA segments with identity to the cloned cDNA of the zebrafish ... 6A) The crabp1a-specific primers generated RTPCR products of the expected size only from RNA of the brain, but not from any other tissues examined including the liver, ovary, skin, intestine,...

Ngày tải lên: 16/03/2014, 22:20

... by inaccurate positioning of the interacting groups The contact area of the distamycin amidinium end was investigated by evaluating the hydrogen positions and interaction energy terms for the interactions ... binding on the DNA conformation is the widening of the minor groove as illustrated in Fig The width of the groove is measured by taking the shortest H5¢–H4¢ distances between the two DNA chains ... propeller twisting of the GC base pair, the cytosine base (its O2 atom) not involved in the calculation helps to lead the guanine amino-group hydrogen atoms away from the drug A search in the Cambridge...

Ngày tải lên: 24/03/2014, 04:21

... achieved in order to fully activate the zymogen Most often in these cases, the need to remove these sequences to obtain full activation is explained by the role of C-terminal determinants in allowing ... been shown that the cysteine-rich domain of PC5 ⁄ 6A was responsible for membrane tethering, thus insuring cell-surface anchoring [37] In other cases, the CT-peptide contains integral transmembrane ... recombinant mPC1 ⁄ 3, the presence of the 87 kDa form in excess of the 66 ⁄ 71 kDa facilitates isolation of the enzyme and helps in maintaining the enzymatic activity at a proper level The observed...

Ngày tải lên: 30/03/2014, 08:20

... replaced with other residues in the corresponding region of SIK2 To examine whether or not the lower similarity in domain 3B between the two isoforms contributes to the difference in their intracellular ... domain are shown The protein kinase A (PKA)dependent phosphorylation sites, Ser577 in SIK1 and Ser587 in SIK2, are indicated in bold The basic residues in domain 3B are indicated by underlines The ... zipper domain (b-ZIP) minus CREB [CREB (S): (right panel)] were investigated by using the Gal4 DNA-binding domain-linked assay Cells were transformed with the Gal4 DNA-binding domain-linked CREB...

Ngày tải lên: 30/03/2014, 15:20

... speci®city of the method was tested by the omission of the primary antibody in the staining, and the use of preimmune serum instead of the ®rst antiserum Furthermore, tissues known to contain UCP2 ... explain the lack of the effect of the transgene on the size of the latter depot [16,17]; this is also associated with the differential effect of the transgene on in situ fatty acid synthesis in the ... during ageing in either genotypes However, as indicated by ANOVA, there was a main effect of genotype in both depots, with transgenic animals showing higher levels of the transcripts Within different...

Ngày tải lên: 31/03/2014, 15:20

... rapidly growing field of research The use of “emerging” is not intended to infer that the presence of these compounds in the environment is new These chemicals have been released into the environment ... they have been in production or, in the case of hormones and other endogenous compounds, since the rise of animal life What is emerging is the interest by the scientific and lay communities in ... prompted interest in sponsoring research that defines the composition and concentrations of PPCPs in potential sources and their fate and effects following release into the environment Independent...

Ngày tải lên: 18/06/2014, 16:20

... be incorporated into the calculation The model calculated the concentration of the veterinary medicine in animal manure and then uses the nitrogen content of the manure and the maximum spreading ... Over the past 10 years the scientific community has become increasingly interested in the impacts of veterinary medicines on the environment, and there have been significant developments in the ... understanding of the inputs of livestock medicines to the environment and synthesizes the available information on the fate and transport of veterinary pharmaceuticals in manure and soils Toward the...

Ngày tải lên: 18/06/2014, 16:20

... 26 26 26 28 32 33 7.1 7.2 Sowing and propagation by cuttings Seeds Direct Sowing 35 35 38 The vegetable garden in the tropics 13 7.3 7.4 7.5 Sowing in a nursery Transplanting Taking cuttings 41 ... mentioned in the bibliography The main objective of this Agrodok is to serve as a general manual for those who practise or teach gardening in developing countries, in order to improve the living conditions ... are listed the most important vitamins vitamin A, or retinol, protects the mucus membranes (nose, mouth) and the skin and plays an important role in vision The body produces this vitamin out of...

Ngày tải lên: 02/07/2014, 05:20

... shown in the table in appendix For more information about gardening or vegetables try consulting some of the books listed in the bibliography 58 The vegetable garden in the tropics Further reading ... an international training institute which focuses on all the links in the production chain on plant and animal commodities, (agricultural) technology, (food) technology and natural areas Training ... researching and promoting organic gardening, farming and food Ryton Organic Gardens, Coventry CV8 3LG, Inited Kingdom Tel: +44 (0)24 7630 3517 Fax: +44 (0)24 7663 9229 60 The vegetable garden in the...

Ngày tải lên: 02/07/2014, 05:20