Nutrition across the lifespan for healthy aging proceedings of a workshop

Leslie Pray, Rapporteur Food Forum Food and Nutrition Board Health and Medicine Division THE NATIONAL ACADEMIES PRESS   500 Fifth Street, NW   Washington, DC 20001 This activity was supported by contracts between the National Academy of Sciences and the National Institutes of Health (HHSN263201200074I); U.S Department of Agriculture (59-1235-2-114, AG-3A94-P-15-0095, CNPP-IOM-FY-2015-01, and FS_NAS_IOM_FY2015_01); and U.S Food and Drug Administration (HHSP233201400020B/HHSP23337012), with additional support by Abbott Laboratories, Incorporated; Cargill, Inc.; The Coca-Cola Company; ConAgra Foods; Dr Pepper Snapple Group; General Mills, Inc.; Kellogg Company; Kraft Heinz; Mars, Inc.; Monsanto; Nestlé Nutrition; Ocean Spray Cranberries, Inc.; PepsiCo; and Tate & Lyle Any opinions, findings, conclusions, or recommendations expressed in this publication not necessarily reflect the views of any organization or agency that provided support for the project International Standard Book Number-13:  978-0-309-45748-4 International Standard Book Number-10:  0-309-45748-3 Digital Object Identifier:  https://doi.org/10.17226/24735 Additional copies of this publication are available for sale from the National Academies Press, 500 Fifth Street, NW, Keck 360, Washington, DC 20001; (800) 6246242 or (202) 334-3313; http://www.nap.edu Copyright 2017 by the National Academy of Sciences All rights reserved Printed in the United States of America Suggested citation: National Academies of Sciences, Engineering, and Medicine 2017 Nutrition Across the Lifespan for Healthy Aging: Proceedings of a Workshop Washington, DC: The National Academies Press doi: https://doi org/10.17226/24735 The National Academy of Sciences was established in 1863 by an Act of Congress, signed by President Lincoln, as a private, nongovernmental institution to advise the nation on issues related to science and ­technology Members are elected by their peers for outstanding contributions to research Dr Marcia McNutt is president The National Academy of Engineering was established in 1964 under the charter of the National Academy of Sciences to bring the practices of engineering to advising the nation Members are elected by their peers for extraordinary contributions to engineering Dr C D Mote, Jr., is president The National Academy of Medicine (formerly the Institute of Medicine) was estab­lished in 1970 under the charter of the National Academy of ­Sciences to advise the nation on medical and health issues Members are elected by their peers for distinguished contributions to medicine and health Dr Victor J Dzau is president The three Academies work together as the National Academies of Sciences, Engineering, and Medicine to provide independent, objective analysis and ­ ­advice to the nation and conduct other activities to solve complex problems and inform public policy decisions The National Academies also encourage education and research, recognize outstanding contributions to knowledge, and increase public understanding in ­matters of science, engineering, and medicine Learn more about the National Academies of Sciences, Engineering, and Medicine at www.national-academies.org Reports document the evidence-based consensus of an authoring committee of experts Reports typically include findings, conclusions, and recommendations based on information gathered by the committee and committee deliberations Reports are peer reviewed and are approved by the National Academies of ­Sciences, Engineering, and Medicine Proceedings chronicle the presentations and discussions at a workshop, symposium, or other convening event The statements and opinions contained in proceedings are those of the participants and have not been endorsed by other participants, the planning committee, or the National Academies of ­Sciences, Engineering, and Medicine For information about other products and activities of the National Academies, please visit nationalacademies.org/whatwedo PLANNING COMMITTEE FOR A WORKSHOP ON NUTRITION ACROSS THE LIFESPAN1 PAMELA STARKE-REED (Chair), Deputy Administrator, Nutrition, Food Safety and Quality, Agricultural Research Service, U.S Department of Agriculture, Beltsville, Maryland JOHANNA DWYER, Senior Nutrition Scientist, Office of Dietary Supplements, National Institutes of Health; Director, Frances Stern Nutrition Center, Tufts-New England Medical Center; Professor, Tufts University Medical School and Friedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts GORDON L JENSEN, Senior Associate Dean for Research, Professor of Medicine and Nutrition, The University of Vermont Larner College of Medicine, Burlington CATHERINE KWIK-URIBE, Global Director, Health and Nutrition, Mars, Inc., Germantown, Maryland SHARON A ROSS, Program Director, Nutritional Science Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Rockville, Maryland MARY T STORY, Professor of Global Health and Community and Family Medicine, Associate Director, Education and Training, Duke Global Health Institute, Duke University, Durham, North Carolina REGINA L TAN, Director, Office of Food Safety, Food and Nutrition Service, U.S Department of Agriculture, Alexandria, Virginia CONNIE WEAVER, Distinguished Professor and Department Head, Department of Nutrition Science, Purdue University, West Lafayette, Indiana 1 The National Academies of Sciences, Engineering, and Medicine’s planning committees are solely responsible for organizing the workshop, identifying topics, and choosing speakers The responsibility for the published Proceedings of a Workshop rests with the workshop rapporteur and the institution v FOOD FORUM1 SYLVIA ROWE (Chair), SR Strategy, LLC, Washington, DC ARTI ARORA, The Coca-Cola Company, Atlanta, Georgia CONNIE AVRAMIS, Unilever Research and Development, Englewood Cliffs, New Jersey FRANCIS (FRANK) BUSTA, University of Minnesota, St Paul PAUL M COATES, Office of Dietary Supplements, National Institutes of Health, Bethesda, Maryland DAVID B COCKRAM, Abbott Laboratories, Incorporated, Columbus, Ohio (through December 2016) NAOMI FUKAGAWA, Agricultural Research Service, U.S Department of Agriculture, Beltsville, Maryland DAVID GOLDMAN, Food Safety and Inspection Service, U.S Department of Agriculture, Washington, DC DANIEL A GOLDSTEIN, Monsanto, St Louis, Missouri DANIELLE GREENBURG, PepsiCo, Purchase, New York SONYA A GRIER, American University, Washington, DC JEAN HALLORAN, Consumers Union, Yonkers, New York JACKIE HAVEN, Center for Nutrition Policy and Promotion, U.S Department of Agriculture, Alexandria, Virginia KATE J HOUSTON, Cargill Inc., Washington, DC LEE-ANN JAYKUS, North Carolina State University, Raleigh GORDON L JENSEN, Pennsylvania State University, University Park (through December 2016) HELEN H JENSEN, Iowa State University, Ames RENÉE S JOHNSON, Library of Congress, Washington, DC WENDY L JOHNSON-ASKEW, Gerber Products Company, Florham Park, New Jersey CHRISTINA KHOO, Ocean Spray Cranberries, Inc., Lakeville, Massachusetts VIVICA KRAAK, Virginia Tech, Blacksburg SUSAN M KREBS-SMITH, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland CATHERINE KWIK-URIBE, Mars, Inc., Germantown, Maryland CHRISTOPHER JOHN LYNCH, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 1 The National Academies of Sciences, Engineering, and Medicine’s forums and roundtables not issue, review, or approve individual documents The responsibility for the published Proceedings of a Workshop rests with the workshop rapporteur and the institution vii SUSAN MAYNE, U.S Food and Drug Administration, College Park, Maryland KAREN McINTYRE, Health Canada, Ottawa, Ontario, Canada S SUZANNE NIELSEN, Purdue University, West Lafayette, Indiana ERIK D OLSON, Natural Resources Defense Council, Washington, DC ROBERT POST, Chobani, LLC, New York, New York KRISTIN REIMERS, ConAgra Foods, Omaha, Nebraska CLAUDIA RIEDT, Dr Pepper Snapple Group, Plano, Texas SARAH ROLLER, Kelley Drye & Warren LLP, Washington, DC SHARON A ROSS, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland JACQUELINE SCHULZ, The Kraft Heinz Company, Northfield, Illinois (through December 2016) LISA SPENCE, Tate & Lyle, Hoffman Estates, Illinois PAMELA STARKE-REED, Agricultural Research Service, U.S Department of Agriculture, Beltsville, Maryland MAHA TAHIRI, General Mills, Inc., Minneapolis, Minnesota REGINA TAN, Office of Food Safety, Food and Nutrition Service, U.S Department of Agriculture Health and Medicine Division Staff HEATHER DEL VALLE COOK, Co-Director LESLIE J SIM, Co-Director ANNA BURY, Research Assistant GERALDINE KENNEDO, Administrative Assistant ANN YAKTINE, Director, Food and Nutrition Board viii Reviewers T his Proceedings of a Workshop has been reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise The purpose of this independent review is to provide candid and critical comments that will assist the institution in making its published Proceedings of a Workshop as sound as possible and to ensure that the Proceedings of a Workshop meets institutional standards for objectivity, evidence, and responsiveness to the study charge The review comments and draft manuscript remain confidential to protect the integrity of the process We wish to thank the following individuals for their review of this Proceedings of a Workshop: LAWRENCE J APPEL, Johns Hopkins Medical Institutions, Baltimore, Maryland DANIEL BELSKY, Duke University, Durham, North Carolina KRISTA SCOTT, Childcare Aware of America, Arlington, Virginia PAMELA STARKE-REED, Agricultural Research Service, U.S Department of Agriculture, Beltsville, Maryland Although the reviewers listed above provided many constructive comments and suggestions, they did not see the final draft of the Proceedings of a Workshop before its release The review of this Proceedings of a Workshop was overseen by JAMES M NTAMBI, University of Wisconsin–Madison He was responsible for making certain that an independent examination of this Proceedings of a Workshop was carried out in accordance with institutional procedures and that all review comments were carefully considered Responsibility for the final content of this Proceedings of a Workshop rests entirely with the rapporteur and the institution ix ... before they became part of the DGA This research, the audience member noted, has helped build a da- 112 NUTRITION ACROSS THE LIFESPAN FOR HEALTHY AGING tabase that can advance understanding of the. .. and activities of the National Academies, please visit nationalacademies.org/whatwedo PLANNING COMMITTEE FOR A WORKSHOP ON NUTRITION ACROSS THE LIFESPAN1 PAMELA STARKE-REED (Chair), Deputy Administrator,... DNA damage with such a small change THE SPECTRUM OF AGING AND HEALTH OVER THE LIFESPAN 25 BIOMARKERS OF AGING2 Ferrucci differentiated between chronological and biological aging The metrics of