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1. Preparation of colloidal chromic phosphate (P32) 1 (chọn)

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EUR 419 e REPRINT EUROPEAN ATOMIC ENERGY COMMUNITY - EURATOM PREPARATION OF COLLOIDAL CHROMIC PHOSPHATE (p32) FOR MEDICAL USE by A M DEL TURCO, R PIETRA 1963 Joint Nuclear Research Centre Ispra Establishment (Italy) Nuclear Chemistry Service Reprinted from International Journal of Applied Radiation and Isotopes Vol 14 1963 - LEGAL NOTICE This document was prepared under the sponsorship of the Commission of the European Atomic Energy Community (EURATOM) Neither the EURATOM Commission, its contractors nor any person acting on their behalf : 1° — Make any warranty or representation, express or implied, with respect to the accuracy, completeness, or usefulness of the information contained in this document, or that the use of any information, apparatus, method, or process disclosed in this document may not infringe privately owned rights; or 2° — any Assume any liability with respect to the use of, or for damages resulting from the use of information, apparatus, method or process disclosed in this document The authors’ names are listed in alphabetical order This reprint is intended for restricted distribution only It reproduces, by kind permission of the publisher, an article from "INTERNA¬ TIONAL JOURNAL OF APPLIED RADIATION AND ISOTO¬ PES”, Vol 14 - 1963, 279-283 For further copies please apply to Pergamon Press Ltd., Journals Department, Headington Hill Hall Oxford {England) — Dieser Sonderdruck ist fur eine beschrdnkte Verteilung bestimmt Die Wiedergabe des vorliegenden in „INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES", Vol 14 - 1963, 279-283 erschienenen Aufsatzes erfolgt mit freundlicher Genehmigung des Herausgebers Bestellungen weiterer Exemplars sind an Pergamon Press Ltd., Journals Department, Headington Hill Hall Oxford {England), zu richten — Ce tiri-a-parl est exclusivement destind a une diffusion restreinte II reprend, avec Vaimable autorisation de Vediteur, un article publie dans le « INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES », Vol 14 - 1963, 279-283 Tout autre exemplaire de cet article, doit litre demande d Pergamon Press Ltd ,Journals Department, Headington Hill Hall Oxford {England) — Questo estratto h destinato esclusivamente ad una diffusione limitata Esso b stato riprodotto, per gentile concessione dellEditore, da ô INTERơ NATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES », Vol 14 - 1963, 279-283 Ulteriori copie dell’articolo debbono essere richieste a Pergamon Press Ltd Journals Department, Headington Hill Hall - Oxford {England) — Deze overdruk is slechts voor beperkte verspreiding bestemd Het artikel is met welwillende toestemming van de uitgever overgenomen uit „INTER¬ NATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES”, Vol 14 - 1963, 279-283 Meer exemplaren kunnen besteld worden bij Pergamon Press Ltd., Journals Department, Hea¬ dington Hill Hall Oxford {England) — EUR e REPRINT PREPARATION OF COLLOIDAL CHROMIC PHOSPHATE MEDICAL USE by A.M DEL TURCO and R PIETRA (P32) FOR European Atomic Energy Community - EURATOM Joint Nuclear Research Centre Ispra Establishment (Italy) Nuclear Chemistry Service Reprinted from "International Journal of Applied Radiation and Isotopes”, Vol 14-1963 - pp 279-283 A method for preparation of radioactive colloidal chromic phosphate (1 mC P32/ mg CrP3204) for medical use has been studied The radioactive colloidal chromic phosphate does not hydrolyse and sediment The particle size of 50 per cent of colloid is about 200 A and the other par¬ ticles are condensed into aggregates EUR e REPRINT PREPARATION OF COLLOIDAL CHROMIC PHOSPHATE MEDICAL USE by A.M DEL TURCO and R PIETRA (P32) FOR European Atomic Energy Community - EURATOM Nuclear Research Centre Ispra Establishment (Italy) Nuclear Chemistry Service Reprinted from "International Journal of Applied Radiation and Isotopes", Vol 14-1903 - pp 279-283 Joint A method for preparation of radioactive colloidal chromic phosphate (1 mC P32/ mg CrP3204) for medical use has been studied The radioactive colloidal chromic phosphate does not hydrolyse and sediment The particle size of 50 per cent of colloid is about 200 A and the other par¬ ticles are condensed into aggregates '1 International Journal of Applied Radiation and Isotopes, 1963, Vol 14, pp 279-283, Pergamon Press Ltd Printed in Northern Ireland Preparation of Colloidal Chromic Phosphate (P32) for Medical Use A M DEL TURCO and R PIETRA Laboratorio di Chimica Nucleare, Euratom, C.C.R.-Ispra, Italy ( Received 26 October 1962 : A method for preparation of radioactive colloidal chromic phosphate (lmCP32/mg CrP3204) for medical use has been studied The radioactive colloidal chromic phosphate does not hydrolyse and sediment The particle size of 50 per cent of colloid is about 200 A and the other particles are condensed into aggregates PREPARATION DU PHOSPHATE (P32j CHROMIQUE COLLOIDAL POUR EMPLOI MEDICAL Une methode pour la preparation du phosphate chromique colloidal radioactif (1 mC p32/mg CrP3204) pour usage medical a etc etudiee Ce radiophosphate chromique colloidal ne s’hydrolvse et ne sedimente pas La grosseur de 50 pour cent des particles du colloldc est de l’ordre de 200 particules sont condensees en agglomeres A et les autres nPIirOTOBJIEIlHE KOJIJIOMflHOrO OOCOATA (P32) XPOMA JDIfl VnOTPE BJIE11MH B MET!IILI II HE II ayita.icu MCTOU iipuroTOujiciiiifl paÿnoaKTiiunoro KO.I.-IOIUIIOIO ({lOCtJiaTa xpo.\ia (Ijiuiopu CrPO32,) ;t.iH ynoTpeS.’ieimn n Meantime PajtHoaKTiiniii.iii Ko.iuonaiiufi i)>oc(j>UT xposia ne nojBepiaeTcn ritapo.utrtv u ne oeantjaeTCH Be.tm'inna aacTiiu 50% no.iaouaa paima npitu.iiiaiiTe.ii.iio 200 A (AnniTpeM), a apyme nacTiiuw KoitaenciijiyioTeH it arpera™ P32/mrp DIE HERSTELLUNG VON KOELOIDALEM CHROMPHOSPEIAT (P32i FUR MEDIZINISCHE ZYVECKE Eine Methode zur Herstellung von radioaktivem kolloidalem C.hromphosphat ( mC p32/mg CrP3204) ist fur den niedizinischen Gcbrauch stiidicrt worden Das so erhaltene radioaktive, kolloidale Chromphosphat hydrolisiert und sedimentiert nicht Die Teilchengrosse von prozent des Kolloids ist ungefahr 200 A und die anderen Teilchen sind zu Aggregaten zusammengeballt INTRODUCTION INTEREST is increasing in the use of colloids of radioactive materials in the therapy of neo¬ plasms HAHN and co-workers*11 have used Au19S in colloidal form in interstitial, intraperitoneal and intravenous routes of administration As early as 1944 JONES and co-workers

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