- Sometimes a lesion will be hypovascular compared to the normal tissue and in some cases a lesion will be hypervascular to the surrounding tissue in a certain phase of enhancement.. -[r]
(1)1
THE TECHNICAL FACTORS AFFECTING THE QUALITY OF DIAGNOSIS IN ABDOMEN OF
CONTRAST – ENHANCED CT
CN: Phạm VănĐiệp CN: Nguyễn Quang Trung
Radiology Department–Hanoi Medical University Hospital
OVERVIEW
• CT scan of the abdomen with an injection of contrast is a method of high diagnostic value in abdominal pathologyg g p gy
• The diagnostic value after the visit depends on the image quality obtained after the scan
• Requirements: Optimal image quality and ensure the lowest di ti d d d
(2)2
- The purpose of contrast-enhanced CT (CECT) is to find pathology by enhancing the contrast between a lesion and the normal
CONTRAST
y g
surrounding structures.
- Sometimes a lesion will be hypovascular compared to the normal tissue and in some cases a lesion will be hypervascular to the surrounding tissue in a certain phase of enhancement.
- So it is important to know in which phase a CT should be performed depending on the pathology of patient
THE PHASES OF CECT
(3)3 Purpose:
NON- ENHANCED CT (NECT)
Purpose:
• Detection of stones in kidney, ureter • Detection of calcifications in liver,
pancreas • Fat inlivertumors • Fat in adrenal adenoma
http://www.radiologyassistant.nl/en/p52c04470dbd5c/ct-contrast-injection-and-protocols.html
(4)4
Timing:
EARLY ARTERIAL PHASE
15-20 sec pre injection or immediately after bolustracking
Purpose:
• Detection of dissection of aorta, arterial bleeding
• Insulinoma
http://www.radiologyassistant.nl/en/p52c04470dbd5c/ct‐contrast‐injection‐and‐protocols.html
(5)5 Timing:
• 35-40 sec p.i or 15-20 sec after
LATE ARTERIAL PHASE
p bolustracking
Purpose:
Detection of
• Liver: HCC-FNH-Adenoma
• Pancreas : Adenocarcinoma, insulinoma
• Bowel ischemia
http://www.radiologyassistant.nl/en/p52c04470dbd5c/ct‐contrast‐injection‐and‐protocols.html
(6)6 Timing:
HEPATIC PHASE
• 70-80 sec p.i or 50-60 sec after bolustracking
Purpose:
• Enhancement of the hepatic parenchyma
• Detection of hypovascular liver lesions: cysts, abscess, most metastases
http://www.radiologyassistant.nl/en/p52c04470dbd5c/ct‐contrast‐injection‐and‐protocols.html
(7)7 Timing:
NEPHROGENIC PHASE
Timing:
• 100 sec p.i or 80 sec after bolustracking
Purpose :
• Enhancement of all renal parenchyma
• Detection of renal cell carcinoma
http://www.radiologyassistant.nl/en/p52c04470dbd5c/ct‐contrast‐injection‐and‐protocols.html
(8)8 Timing:
DELAYED PHASE
• After 6-10 minutes p.i
Purpose:
• Enhancement of fibrotic lesions
• Enhancement of kidney and urinary
collecting system
• Detection of cholangiocarcinoma, transitional cell carcinoma
cell carcinoma
http://www.radiologyassistant.nl/en/p52c04470dbd5c/ct‐contrast‐injection‐and‐protocols.html
(9)9 TIMING OF CT-SERIES THE FACTORS TOTAL AMOUNT OF CONTRAST INJECTION RATE ANOTHER FACTORS
-In many protocols a standard dose is given related to the weight of
Total amount of
contrast
the patient:
Weight < 75kg : 100cc Weight 75-90kg: 120cc Weight > 90kg : 150cc
In some protocols we always want to give the maximum dose of - In some protocols we always want to give the maximum dose of
150cc, like when you are looking for a pancreatic carcinoma or liver
metastases
(10)10
CREATININE CLEARANCE
https://www.mdcalc.com/creatinine‐clearance‐cockcroft‐gault‐equation
• Recommended injection rate of 5cc/sec using G18 I.V
h l ti th ki ti f l i
INJECTION RATE
when evaluating the kinetics of lesions
• Unneccessary in case just focus at hepatic phase or having problem with machine, line,
(11)11
INJECTION RATE
Patient with liver cirrhosis and multifocal HCC injected at 2.5 ml/sec and at 5ml/sec
INJECTION RATE
Food and Drug Administration (FDA)-approved devices for power/pressure injection as below:
Injection rates for 24G catheters up to ml/s Injection rates for 22G catheters up to ml/s Injection rates for 20G catheter up to ml/s Injection rates for 18G catheter up to ml/s
(12)12
TIMING OF CT-SERIES
Timing of CT-series is important in order to grab the right moment of maximal contrast differences between a lesion and the normal parenchyma
The protocol we choose to visit depends very much on the clinical diagnosis
CT generation
Supply of heart and body condition of patients
LIVER
The phases :
NECT (non-enhanced CT) Arterial phase (35 sec) Hepatic phase (70 sec) Delayed phase (3 - mins)
(13)13
LIVER
(14)14 https://www.acr.org/‐/media/ACR/Files/RADS/LI‐RADS/LI‐RADS‐2018‐Core.pdf?la=en
PANCREAS
(15)15
PANCREAS
a: pre- contrast b: 35s c: 55s d: 80s
PANCREAS
(16)16
URINARY
URINARY
Kidney injury with delayed phase
(17)17
INJURY
Spleen injury with arterial phase
HEMORRHAGIC
(18)18
BLOOD VESSEL
Dissection of superior mesenteric artery
Depending on machines, equipment, medical facility.
ANOTHER FACTORS
Factors of age, weight, heart disease, vascular.
Experience of doctor and technicians.
(19)19 The delay time of post injection should be determined by
ANOTHER FACTORS
considering three factors:
● Time of contrast injection
● Arrival time of contrast medicine
● Scanning time (depending on the type of CT machine)
CECT is a valuable diagnostic method, especially in emergency medical conditions
CONCLUDE
For good diagnostic results, the image quality after scan is very important
Equipment and experience of technicians is very important Collaboration between doctors and technicians
(20)20 •
http://www.radiologyassistant.nl/en/p52c04470dbd5c/ct-contrast-i j thttp://www.radiologyassistant.nl/en/p52c04470dbd5c/ct-contrast-i d t l ht l
References
injection-and-protocols.html
• https://www.radiologyinfo.org/en/info.cfm?pg=safety-radiation • Split-Bolus MDCT Urography with Synchronous Nephrographic and
Excretory Phase Enhancement
• How Much Dose Can Be Saved in Three-Phase CT Urography? •
https://www.acr.org/-/media/ACR/Files/RADS/LI-RADS/LI-RADS-2018-Core.pdf?la=enp
(21)21 THANK YOU !
hinhanhykhoa.com