Test Bank Genetic Analysis An Integrated Approach 3rd Edition Mark F Sanders Exam Full file at https://TestbankHelp.eu/ Name _ MULTIPLE CHOICE Choose the one alternative that best completes the statement or answers the question 1) A genetic counselor A) chooses the best course of action for patients based on genetic testing B) designs genetic tests that can be used in population-level testing programs C) performs genetic testing and reports their findings to a medical doctor D) performs gene therapy E) helps patients choose whether or not they will undergo genetic testing, explains the results of genetic tests, and helps patients make their own medical decisions 1) Answer: E 2) Pedigrees are useful for A) parents who want to determine how many kids to have B) discovering patterns of inheritance that may suggest familial disease C) determining the paternity of a child D) for genetics classes but they have little applicability to modern medical care E) doctors so that they can treat all affected members of a family 2) Answer: B 3) A patient with monosomy is most easily diagnosed using what technique? A) a pedigree B) PCR C) the expression of recessive traits D) a karyotype E) questioning the parents of that patient 3) Answer: D 4) Genetic testing includes all of the following except A) presymptomatic testing B) prenatal testing C) carrier testing D) newborn testing E) all of these are forms of genetic testing 4) Answer: E 5) In genetics, Baysian analysis uses A) DNA sequencing to determine the genotype of an individual B) known or inferred genotype information, along with information from related offspring to make predictions about the probability of a certain genotype in an individual C) numerical information to predict the chance of disease D) court testimony to determine the chance of disease in an individual E) electrophoresis to determine the genotype of an individual Answer: B Full file at https://TestbankHelp.eu/ 5) Test Bank Genetic Analysis An Integrated Approach 3rd Edition Mark F Sanders Full file at https://TestbankHelp.eu/ 6) The chance of each of two independent events happening are to determine the probability that both events would happen together A) squared B) added together C) divided by two D) multiplied by each E) multiplied by two 6) Answer: D 7) A testing outcome in which a disease is detected, but the sample/patient in reality does not have the disease is called a A) false negative B) a standard error C) true positive D) false positive E) a true negative 7) Answer: D 8) A maternal serum screen can be performed to detect which provide information about the genotype of a fetus A) circulating compounds B) precancerous cells C) maternal DNA D) RNA fragments E) blood cells 8) Answer: A 9) Consider a particular hypothetical case in which the Baysian probability that an unaffected parent is heterozygous for a particular recessive allele is 20% and the other parent has the recessive condition; what is the chance that their first child would have the condition? A) 10% B) 20% C) 25% D) 100% E) 0% 9) Answer: A 10) A pregnant woman with recessive X-linked hemophilia and whose partner is a normal (non hemophiliac) man wants to know the chances that she will have an affected child From an ultrasound, she knows that the child is a boy What are the chances that her son will have hemophilia? A) the chance that their son will be affected is 0% B) the chance that their son will be affected is 100% C) the chance that their son will be affected is 50% D) the chance that their son will be affected is 75% E) the chance that their son will be affected is 25% Answer: B Full file at https://TestbankHelp.eu/ 10) Test Bank Genetic Analysis An Integrated Approach 3rd Edition Mark F Sanders Full file at https://TestbankHelp.eu/ 11) Two unaffected parents each have a parent with the same recessive condition and they want to know the chances that they will have a child who has the condition What you tell them? A) the chance that their child will be affected is 0% B) the chance that their child will be affected is 100% C) the chance that their child will be affected is 25% D) the chance that their child will be affected is 75% E) the chance that their child will be affected is 50% 11) Answer: C 12) The ethical issues guiding genetic counseling include all except A) preventing any coercion regarding patient decisions B) the benefits to society of having an individual tested C) respect for individual autonomy D) the likelihood of medical benefit E) justice — the equal treatment of all individuals 12) Answer: B 13) allows doctors to intervene in cases of rare disease to mitigate disease, often by simply prescribing dietary supplementation or restricting certain substances from the diet of affected individuals A) Direct-to-consumer genetic testing B) Carrier testing C) Population testing D) Paternity testing E) Newborn testing 13) Answer: A 14) The only form of genetic testing that is mandated in the United States is A) carrier testing B) population testing C) newborn testing D) paternity testing E) prenatal testing 14) Answer: C 15) A couple comes to you for advice about genetic testing for a rare early-onset dominant condition The paternal grandfather had the condition, but no one else in the family has had it including the male partner in this couple Do you recommend testing? Why? A) yes, testing is expensive, but worth the price, even when unnecessary B) no, the male partner is definitely a carrier and so the outcome is certain C) yes, the male partner is definitely a carrier D) no, we can deduce that neither partner has a disease allele E) no, both parents would have to have the disease allele to have an affected child Answer: D Full file at https://TestbankHelp.eu/ 15) Test Bank Genetic Analysis An Integrated Approach 3rd Edition Mark F Sanders Full file at https://TestbankHelp.eu/ 16) A couple has just been informed that one of them has Huntington's disease, and that the other spouse does not have a disease allele With this information, what is the chance that at least one of their two young children has a disease allele? A) the chance that at least one of the unaffected children has a disease allele is 75% B) the chance that at least one of the unaffected children has a disease allele is 100% C) the chance that at least one of the unaffected children has a disease allele is 50% D) the chance that at least one of the unaffected children has a disease allele is 25% E) the chance that at least one of the unaffected children has a disease allele is 0% 16) Answer: A 17) A family with only one affected parent and a child with a dominant disease would like to know what the probability is that one of their unaffected children might be a carrier What you tell them? A) the chance that an unaffected child is a carrier is 50% B) the chance that an unaffected child is a carrier is less than 50% C) the chance that an unaffected child is a carrier is 0% D) the chance that an unaffected child is a carrier is 75% E) the chance that an unaffected child is a carrier is 2/3 17) Answer: C 18) A family with two unaffected parents and a child with a recessive disease would like to know what the probability is that one of their unaffected children might be a carrier What you tell them? A) the chance that an unaffected child is a carrier is less than 50% B) the chance that an unaffected child is a carrier is 2/3 C) the chance that an unaffected child is a carrier is 0% D) the chance that an unaffected child is a carrier is 75% E) the chance that an unaffected child is a carrier is 50% 18) Answer: B 19) A couple comes to you for genetic counseling and the male partner has a rare mitochondrial disease What you tell them about the chance that their first child would have the disease? A) the first child can be screened using in vitro fertilization, so no testing is necessary B) the first child will only have the disease is they are male C) the first child will have no chance of inheriting the disease D) the child will have the disease because mitochondria are inherited paternally E) the first child will only have the disease is they are female 19) Answer: C 20) A boy with recessive X-linked hemophilia is born from an unaffected mother and a father with hemophilia From which parent was the disease allele inherited? A) the father or the mother with an equal chance of either parent B) the mother C) the father D) any of these answers is equally likely E) both parents, the trait is recessive Answer: B Full file at https://TestbankHelp.eu/ 20)