Clinicopathological variables influencing overall survival, recurrence and postrecurrence survival in resected stage I nonsmall-cell lung cancer

To investigate clinicopathological variables influencing overall survival, overall recurrence, and postrecurrence survival (PRS) in patients who experienced curative-intent surgical resection of stage I non-small-cell lung cancer (NSCLC).

Wang et al BMC Cancer (2020) 20:150 https://doi.org/10.1186/s12885-020-6621-1 RESEARCH ARTICLE Open Access Clinicopathological variables influencing overall survival, recurrence and postrecurrence survival in resected stage I nonsmall-cell lung cancer Chengdi Wang , Yuxuan Wu , Jun Shao , Dan Liu* and Weimin Li* Abstract Background: To investigate clinicopathological variables influencing overall survival, overall recurrence, and postrecurrence survival (PRS) in patients who experienced curative-intent surgical resection of stage I non-small-cell lung cancer (NSCLC) Methods: We investigated a series of 1387 patients with stage I NSCLC who underwent surgical resection from 2008 to 2015 The effect clinicopathological factors on death, recurrence, and PRS were evaluated by Kaplan-Meier estimates and cox regression analysis Results: Among the 1387 stage I patients, 301 (21.7%) experienced recurrence The 5-year cumulative incidence of recurrence (CIR) for all patients was 20.2% and median PRS was 25.5 months The older age (P = 0.036), p-stage IB (P = 0.001), sublobar resection(P