Predictors of severity and outcome of global developmental delay without definitive etiologic yield: A prospective observational study

Although several determinants of global developmental delay (GDD) have been recognized, a significant number of children remain without definitive etiologic diagnosis. The objective of this study was to assess the effect of various prenatal and perinatal factors on the severity and outcome of developmental delay without definitive etiologic yield.

Thomaidis et al BMC Pediatrics 2014, 14:40 http://www.biomedcentral.com/1471-2431/14/40 RESEARCH ARTICLE Open Access Predictors of severity and outcome of global developmental delay without definitive etiologic yield: a prospective observational study Loretta Thomaidis1, Georgios Zacharias Zantopoulos1,2*, Sotirios Fouzas2, Lito Mantagou2, Chryssa Bakoula1 and Andreas Konstantopoulos1 Abstract Background: Although several determinants of global developmental delay (GDD) have been recognized, a significant number of children remain without definitive etiologic diagnosis The objective of this study was to assess the effect of various prenatal and perinatal factors on the severity and outcome of developmental delay without definitive etiologic yield Methods: From March 2008 to February 2010, 142 children with developmental quotient (DQ)