Candida esophagitis (pdf io)

Candida Esophagitis Takeshi Kondo, M.D., and Kazuhiko Terada, M.D April 20, 2017 N Engl J Med 2017; 376:1574 DOI: 10.1056/NEJMicm1614893 A 72-year-old man presented with a 2-week history of odynophagia [nuốt đau] (pain [đau] on swallowing [nuốt]) Sixteen months before the onset [khỏi phát] of this symptom [triệu chứng], the patient [bệnh nhân] had received a diagnosis [chẩn đoán] of diffuse panbronchiolitis [viêm toàn tiểu phế quản lan tỏa], and he had been receiving long-term treatment [điều trị] with macrolide antibiotics [kháng sinh nhóm macrolide] since then He had not received glucocorticoids or other immunosuppressant medications [thuốc ức chế miễn dịch] Upper endoscopy [nội soi] [also known as esophagogastroduodenoscopy (EGD) nội soi thực quản – dày – tá tràng] revealed linear, white, mucosal [niêm mạc], plaquelike lesions [thương tổn] on the esophagus [thực quản] (Panel A) No oropharyngeal [adj: hầu - họng] or gastroduodenal [adj: dày - tá tràng] lesions were noted The diagnosis of candida esophagitis [viêm thực quản nấm candida] was made on the basis of the characteristic endoscopic findings and was confirmed by a culture [nuôi cấy] of esophageal brushing samples [mẫu phết thực quản] that was positive [dương tính] for Candida albicans A serologic test [xét nghiệm huyết học] for human immunodeficiency virus [HIV – virus gây suy giảm miễn dịch người] was negative [âm tính] Candida esophagitis is a common opportunistic infection [nhiễm trùng hội] in immunocompromised hosts [vật chủ bị tổn thương hệ miễn dịch] Long-term treatment with antibiotics [kháng sinh] can be a risk factor [yếu tố nguy cơ] in immunocompetent patients [bệnh nhân có hệ miễn dịch bình thường] Oral antifungal therapy [liệu pháp điều trị kháng nấm đường uống] was initiated in the patient, and within weeks after starting therapy, his pain on swallowing was reduced A repeat endoscopy performed 12 weeks after the initiation of antifungal therapy [liệu pháp điều trị] showed a marked reduction in the number and severity of esophageal lesions [thương tổn thực quản] (Panel B) Takeshi Kondo, M.D Kazuhiko Terada, M.D Chiba University Hospital, Chiba, Japan ... or gastroduodenal [adj: dày - tá tràng] lesions were noted The diagnosis of candida esophagitis [viêm thực quản nấm candida] was made on the basis of the characteristic endoscopic findings and... [dương tính] for Candida albicans A serologic test [xét nghiệm huyết học] for human immunodeficiency virus [HIV – virus gây suy giảm miễn dịch người] was negative [âm tính] Candida esophagitis is