Pharmacology, which is the science of drugs, is a great responsibility to any allied health professional. Medication mistakes made can injure or even cause the death of a patient. It is important to begin with a good working knowledge of the foundations of pharmacology. This chapter provides an overview of the role of drugs in ambulatory medical facilities.
CHAPTER 50 Principles of Pharmacology © 2011 The McGraw-Hill Companies, Inc All rights reserved 502 Learning Outcomes 50.1 Describe the five categories of pharmacology 50.2 Differentiate between chemical, generic, and trade names for drugs 50.3 Describe the major drug categories 50.4 Identify the main sources of drug information © 2011 The McGraw-Hill Companies, Inc All rights reserved 503 Learning Outcomes (cont.) 50.5 Distinguish between over-the-counter and prescription drugs 50.6 Compare the five schedules of controlled substances 50.7 Describe how to register or renew a physician with the Drug Enforcement Administration (DEA) for permission to administer, dispense, and prescribe controlled drugs © 2011 The McGraw-Hill Companies, Inc All rights reserved 504 Learning Outcomes (cont.) 50.8 Carry out the procedure for renewing medications using a telephone 50.9 Describe how vaccines work in the immune system 50.10 Organize patient education topics related to the use of nonprescription and prescription drugs © 2011 The McGraw-Hill Companies, Inc All rights reserved 505 Introduction • Pharmacology – science or study of drugs • Medication errors can result in injury or death • Medical assistant – Knowledge of the foundations of pharmacology – Understand role of drugs in ambulatory medical facilities © 2011 The McGraw-Hill Companies, Inc All rights reserved 506 Medical Assistant’s Role in Pharmacology • Prescription drugs – physician’s order required to dispense and administer • OTC drugs – purchased by patient for self-treatment • You should – Be sure the physician is aware of all medications the patient is taking – Ask patients about use of alcohol and recreational drugs – Provide patient education © 2011 The McGraw-Hill Companies, Inc All rights reserved Medical Assistant’s Role in Pharmacology 507 (cont.) • Administration of drugs – Check state regulations scope of practice – Understand pharmacologic principles – Translate prescriptions – Answer basic patient questions – Adhere to legal requirements – Keep accurate records © 2011 The McGraw-Hill Companies, Inc All rights reserved 508 Drugs and Pharmacology • Drug – chemical compound used to prevent, diagnose, or treat disease • Pharmacognosy – study of characteristics of natural drugs and their sources • Pharmacodynamics – study of what drugs to the body © 2011 The McGraw-Hill Companies, Inc All rights reserved 509 Drugs and Pharmacology (cont.) • Pharmacokinetics – study of what the body does to drugs • Pharmacotherapeutics – study of how drugs are used to treat disease • Toxicology – study of poisons or poisonous effects of drugs © 2011 The McGraw-Hill Companies, Inc All rights reserved 5010 Drugs and Pharmacology (cont.) • Prescribe – physician gives a patient a prescription to be filled by a pharmacist • Administer – give a drug by injection, mouth, or other route that introduces it into the body • Dispense – health-care professional distributes the drug, in a properly labeled container, to the patient for whom it is prescribed © 2011 The McGraw-Hill Companies, Inc All rights reserved 5037 Vaccines • Special preparations made from microorganisms • Administered to produce reduced sensitivity to or increased immunity to an infectious disease • Body creates antibodies in response to an antigen (vaccine) © 2011 The McGraw-Hill Companies, Inc All rights reserved 5038 Antibody Formation Antigen enters body White cells produce antibodies Antibodies combine with antigens to neutralize them This arrests or prevents reaction or disease Vaccines stimulate antibody formation and reduce symptoms if patient is exposed to disease © 2011 The McGraw-Hill Companies, Inc All rights reserved 5039 Immunizations • Schedule for immunizations for children up to age 16 years • Pre-exposure immunizations • Post-exposure immunizations – antiserum or antitoxin that contains antibodies © 2011 The McGraw-Hill Companies, Inc All rights reserved 5040 Immunizations (cont.) • Medical assistant should be familiar with – Indications – Contraindications – Dosages – Administration routes – Potential adverse effects – Methods of storing and handling © 2011 The McGraw-Hill Companies, Inc All rights reserved 5041 Apply Your Knowledge Why are vaccines given to patients? ANSWER: Vaccines are administered to a person to produce reduced sensitivity to or increase immunity to an infectious disease © 2011 The McGraw-Hill Companies, Inc All rights reserved 5042 Patient Instruction on Medications • Medical assistant role is important • OTC drugs – Should not be used to avoid medical care – May not produce enough therapeutic benefit – May be dangerous in combination with other substances or drugs – May mask symptoms or aggravate a problem © 2011 The McGraw-Hill Companies, Inc All rights reserved 5043 Patient Instruction on Medications (cont.) • Prescription drugs – Inform patient about special considerations and drug safety precautions – Encourage patient to • Maintain a complete list of medications • Report adverse reactions Patient compliance â 2011 The McGraw-Hill Companies, Inc All rights reserved 5044 Patient Instruction on Medications (cont.) • To prevent medication errors, be sure patient understands prescription – How and when to take the medication – Appropriate language – Demonstrate if necessary – Review warnings about the medication © 2011 The McGraw-Hill Companies, Inc All rights reserved 5045 Apply Your Knowledge Mrs Del Rosario tells you she does not take any medication when you are taking her history When you question her further, she says she takes an OTC pain medication occasionally and routinely take several herbal supplements What should you tell her? ANSWER: You should tell her it is important to report all medications, including OTC drugs and herbal and other supplements, to the physician and that they may be dangerous in combination with other substances or drugs or may mask symptoms or aggravate a problem Nice Job! © 2011 The McGraw-Hill Companies, Inc All rights reserved 5046 In Summary 50.1 The five categories of pharmacology include pharmacognosy, pharmacokinetics, pharmacodynamics, pharmacotherapeutics, and toxicology 50.2 The chemical name of a drug is based upon the chemical makeup of the medication The generic name is the drug’s official name, and the trade name is the name given a medication by the manufacturer A medical assistant should be familiar with both the generic and trade names © 2011 The McGraw-Hill Companies, Inc All rights reserved 5047 In Summary (cont.) 50.3 Drug categories are sometimes named based upon their action; for example, anticonvulsants are used to treat convulsions (seizures) The major drug categories and their actions are outlined in Table 502 50.4 The main book sources for drug information are the Physicians’ Desk Reference (PDR), Drug Evaluations, United States Pharmacopeia/National Formulary, and the American Hospital Formulary Service You may also access medication information from package inserts, at the web site www.rxlist.com, or at other reliable Internet sites © 2011 The McGraw-Hill Companies, Inc All rights reserved 5048 In Summary (cont.) 50.5 Nonprescription or over-the-counter drugs can be obtained without a physician’s order For prescription drugs, patients must have a physician’s order 50.6 For drugs that have been classified as controlled substances because they are potentially dangerous and addictive, extensive regulations apply There are five schedules (I to V) of controlled substances, with schedule I being the most addictive © 2011 The McGraw-Hill Companies, Inc All rights reserved 5049 In Summary (cont.) 50.7 All physicians must be registered with the Drug Enforcement Administration and follow the legal requirements of the Controlled Substances Act of 1970 to administer, dispense, and prescribe controlled drugs The medical assistant must follow these legal requirements when registering the physician 50.8 Receiving and telephoning medication refills is frequently done by the medical assistant for all medications except schedule II and III drugs © 2011 The McGraw-Hill Companies, Inc All rights reserved 5050 In Summary (cont.) 50.9 Immunizations usually contain killed or weakened organisms When given, they stimulate the body to build up a resistance to the organism They are used to provide immunity against specific diseases 50.10 Patients should be educated about why, when, and how they should take medications This includes instruction to ensure patient compliance regarding nonprescription and prescription drugs, herbal remedies, and supplements Patients should also be instructed about the dangers of medication combinations, the importance of reporting an adverse effect, and maintaining a complete medication list © 2011 The McGraw-Hill Companies, Inc All rights reserved 5051 End of Chapter 50 It is easy to get a thousand prescriptions but hard to get one single remedy. ~Chinese Proverb © 2011 The McGraw-Hill Companies, Inc All rights reserved ... manufacturing – – – – Identity Strength Purity Quality • OTC drugs • Prescription drugs • Pregnancy categories – – – – – A B C D X © 2011 The McGraw-Hill Companies, Inc All rights reserved 50 29 Controlled... Clinical pharmacology • Drug names – Generic – official name – International nonproprietary name – Chemical name – Trade – brand or proprietary name • Generic and trade names used most often ©... rights reserved 50 11 Sources of Drugs • Natural products – Plants – Animals – Minerals – Bacteria and fungi Foxglove – source of digitoxin • Chemical development of natural products – Synthesis