Part 1 book “Gynecologic oncology clinical practice and surgical atlas” has contents: Epidemiology of gynecologic cancers, clinical trials, and statistical considerations, genetics and biology of gynecologic cancers, diagnostic modalities, cervical cancer, endometrial hyperplasia and cancer, uterine sarcomas, gestational trophoblastic disease,… and other contents.
NOTICE Medicine is an ever-changing science As new research and clinical experience broaden our knowledge, changes in treatment and drug therapy are required The authors and the publisher of this work have checked with sources believed to be reliable in their efforts to provide information that is complete and generally in accord with the standards accepted at the time of publication However, in view of the possibility of human error or changes in medical sciences, neither the authors nor the publisher nor any other party who has been involved in the preparation or publication of this work warrants that the information contained herein is in every respect accurate or complete, and they disclaim all responsibility for any errors or omissions or for the results obtained from use of the information contained in this work Readers are encouraged to confirm the information contained herein with other sources For example and in particular, readers are advised to check the product information 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content of any information accessed through the work Under no circumstances shall McGraw-Hill and/or its licensors be liable for any indirect, incidental, special, punitive, consequential or similar damages that result from the use of or inability to use the work, even if any of them has been advised of the possibility of such damages This limitation of liability shall apply to any claim or cause whatsoever whether such claim or cause arises in contract, tort or otherwise Dedication This textbook and all of our professional accomplishments would not be possible without the enduring support of our families We dedicate this effort to our understanding spouses, Scott, Michelle, and Cathy; our high-spirited children, Matthew and Jocelyn Karlan, Jackson, Chloe, and Haley Bristow, Jason, Lucas, and Evan Li; and to our loving parents, Beverly and Stanley Young, Lynn and Lonnie Bristow, and Chien and Marian Li, who raised us with passions for caring and eternal learning Our many teachers and mentors provided us with the knowledge and skills to care for women with gynecologic cancers and motivated us to continue pushing the therapeutic envelope until cures are within our grasp Our colleagues—physicians, scientists, nurses, and other professionals—work shoulder to shoulder with us, and support, challenge, motivate, and make us laugh when it is most needed And most importantly, this book is dedicated to the legions of women with gynecologic cancer, both living and in our memories, who have taught us tenacity, selflessness, and courage We hope that this text will educate future generations of clinicians and scientists whom we can enlist on our journey to end cancer as a threat to women Contents Contributors Preface FUNDAMENTAL TOPICS Epidemiology of Gynecologic Cancers, Clinical Trials, and Statistical Considerations Wendy R Brewster and Krishnansu S Tewari Genetics and Biology of Gynecologic Cancers Douglas A Levine Diagnostic Modalities David Starks, Bin Yang, and Peter G Rose DISEASE SITES Preinvasive Disease of the Lower Genital Tract Levi S Downs Jr and Jori S Carter Cervical Cancer Angela J Ziebarth, Kenneth H Kim, and Warner K Huh Endometrial Hyperplasia and Cancer David A Iglesias, Marilyn Huang, Pamela T Soliman, Bojana Djordjevic, and Karen H Lu Uterine Sarcomas Gary S Leiserowitz Gestational Trophoblastic Disease Diljeet K Singh Vulvar Cancer Mark Milam and Charles F Levenback 10 Vaginal Cancer William J Lowery, Junzo Chino, and Laura J Havrilesky 11 Management of the Adnexal Mass Ritu Salani and Christa Nagel 12 High-Grade Serous Carcinomas of the Ovary, Fallopian Tube, and Peritoneum David E Cohn and Ronald D Alvarez 13 Epithelial Ovarian Cancers: Low Malignant Potential and Non-Serous Ovarian Histologies Gregory P Sfakianos, Angeles Alvarez Secord, and Ie-Ming Shih 14 Germ Cell and Sex Cord-Stromal Ovarian Cancers Susan C Modesitt and Jubilee Brown 15 Breast Cancer and Related Diseases Catherine M Dang and M William Audeh 16 Cancer in Pregnancy Malaika Amneus and Christine H Holschneider 17 Metastases to the Gynecologic Tract S Diane Yamada and Nita K Lee III CLINICAL MANAGEMENT TOPICS 18 Perioperative and Critical Care Renata Urban and Lee-may Chen 19 Principles of Radiation Therapy Wui-Jin Koh and Lindsay R Sales 20 Principles of Chemotherapy Ursula A Matulonis 21 Targeted Therapy and Immunotherapy Robert L Coleman and Paul J Sabbatini 22 Integrative Oncology, Quality of Life, and Supportive Care Diljeet K Singh and Vivian E von Gruenigen 23 Surgical Instrumentation and Sutures John C Elkas and Addie Alkhas IV SURGICAL ATLAS 24 Ovarian and Fallopian Tube Procedures Eric L Eisenhauer and Jeffrey M Fowler 25 Uterine Procedures John O Schorge and David M Boruta II 26 Cervical Procedures Danielle Vicus and Allan Covens 27 Vulvar and Vaginal Excisional Procedures Mark A Morgan, Sarah H Kim, and Sameer A Patel 28 Lymphadenectomy Lisa A dos Santos and Nadeem R Abu-Rustum 29 Staging Procedures Summer B Dewdney and Matthew 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Surgery and Robotics Section of Gynecologic Oncology Department of Obstetrics and Gynecology Cleveland Clinic Cleveland, Ohio Chapter 31 Jeffrey M Fowler, MD John G Boutselis Professor in Gynecologic Oncology Department of Obstetrics... Lowery, MD Gynecologic Oncology Fellow Division of Gynecologic Oncology Duke University Medical Center Durham, North Carolina Chapter 10 Karen H Lu, MD Professor Department of Gynecologic Oncology and Reproductive Medicine University of... Integrative Oncology, Quality of Life, and Supportive Care Diljeet K Singh and Vivian E von Gruenigen 23 Surgical Instrumentation and Sutures John C Elkas and Addie Alkhas IV SURGICAL ATLAS 24 Ovarian and Fallopian Tube Procedures