Objectives: Evaluation of technical success as complete ablation rate, tumor progression, the safety and short-term outcome of radiofrequency ablation (RFA) in hepatocellular carcinoma (HCC). Subjects and methods: 30 patients with HCC were treated with radiofrequency ablation from Jun 1, 2014 to Jun 1, 2017 at Binhdan Hospital.
gery, only one case with minor complication accounted for 3.3% The patient developed punction-site abscess week after the first RFA treatment and was treated with 194 percutaneous drainage with antibiotics, he later went well and was discharged of the hospital the day later DISCUSSION Today, liver resection is still the best treatment method for HCC in both overall survival rate and recurrent rate Despite the good outcome, hepatectomy carries lot of risks with high mortality rate and complications, thus HCC usually develops on liver with severe cirrhosis which made the conservation of the normal liver tissue a big problem Luckily, RFA is an well alternative choice to treat HCC with its good result and it is now widely accepted Moreover, RFA is a less invasive therapy and can be repeat easily to treat recurrent cases Data strongly support RFA as an effective treatment for single HCC ≤ cm even when surgical resection is possible [1, 8] As recently report for RFA in size less than 3.5 cm, the technical efficacy (complete tumor ablation) ranged from 76% to 96% of nodules after session, and could be up to 100% after sessions In our studies, we archived a complete ablation rate at 90% on patients-basis Journal of military pharmaco-medicine no4-2018 Recent evidence supported percutaneous local ablative therapy for small HCC considered as effective as liver resection [1, 6] its indications to help treat larger lesion with stronger ablative needle In our group, survival rate at year followed-up was 100%, with no treatmentrelated deaths, no major complications with only one local minor complication Andrea Salmi Efficacy of radiofrequency ablation of hepatocellular carcinoma associated with chronic liver disease without cirrhosis International Journal of Medical Sciences 2008, (6), pp.327-332 Local recurrence rates varies from 12% to 36% at months and from 16% to 38% at 12 months follow-up after RFA [3] Our study recorded the recurrent rates at and 12 months were 23.33% and 30%, respectively Bruix Jordi, Sherman Morris Management of HCC: an update Hepatology 2011, pp.1020-1022 Junichi Toshimori et al studied 397 cases of HCC treated with RFA and reported that large tumor size (> cm), tumor location (adjacent to major portal or hepatic vein/biliary duct or major visceral and diaphragm) and small ablated margin (< mm) were independent predictor factors for local recurrence after RFA [5] In our studies, we also noticed the same results with factors which contributed to recurrence were: tumor size > cm (100% of local recurrent at and 12 months had lesions larger than cm), tumor in the difficult location to ablate (3 on local recurrent lesions at 12 months) and uneffective post RFA antiviral treatment CONCLUSION In conclusion, RFA is a safe and effective curative treatment for early-stage HCC, alternative to liver resection Thus, the therapy is developing a lot to expand REFERENCES Courtney L Scaife Complication, local recurrence and survival rates after RFA for hepatic malignancies Surg Oncol Clin N Am 2003, vol 12, pp.243-255 Josep M Llovet The Barcelona approach: Diagnosis, staging and treatment of HCC Liver Transplation 2004, 10 (2), suppl 1, pp.S115-S120 Junichi Toshimori Local recurrence and complications after percutaneous RFA of HCC: a retrospective cohort study focused on tumor location Acta Med Okayama 2015, 69 (4), pp.219-226 Gugliemi A, Ruzzenante A Radiofrequency ablation versus surgical resection for the treatment of small HCC in cirrhosis J Gastrointest Surg 2008, 12 (1), pp.192-198 Ronnie T.P Poon Locoregional therapies for HCC: A critical review from surgeon’s perspective Annals of Surg 2002, 235 (4), pp.466-486 S.M Lin, C.C Lin, Lin C.J et al Randomised controlled trial comparing percutaneous radiofrequency thermal ablation, percutaneous ethanol injection, percutaneous acetic acid injection to treat HCC of cm or less Gut 2005, 54 (8), pp.1151-1156 195 ... local minor complication Andrea Salmi Efficacy of radiofrequency ablation of hepatocellular carcinoma associated with chronic liver disease without cirrhosis International Journal of Medical Sciences... indications to help treat larger lesion with stronger ablative needle In our group, survival rate at year followed-up was 100%, with no treatmentrelated deaths, no major complications with only one... Morris Management of HCC: an update Hepatology 2011, pp.1020-1022 Junichi Toshimori et al studied 397 cases of HCC treated with RFA and reported that large tumor size (> cm), tumor location (adjacent