High Yield Warm-up Questions: Musculoskeletal and Connective Tissue, Part B ORGAN SYSTEMS SET 4: MUSCULOSKELETAL AND CONNECTIVE TISSUE, PART B What drug is used as an alternative to NSAIDs in patients with acute gout attacks? Overdose with acetaminophen is managed with N-acetylcysteine What is the rationale behind this antidote? A patient with rheumatoid arthritis is started on a drug that selectively inhibits COX-2 enzymes Caution must be observed in patients who take this drug and are allergic to what type of drug? What are important risk factors for osteoarthritis? Which of the arthritic diseases are seronegative spondyloarthropathies? What bacteria are most commonly implicated in acute infectious arthritis? Name three muscular compartments of the lower limb that are innervated by branches of the tibial nerve Compare and contrast the functions of the obturator and femoral nerves 1 High Yield Warm-up Questions: Musculoskeletal and Connective Tissue, Part B A lesion of the common fibular nerve would result in altered sensation in what regions of the lower limb, and motor weakness in what lower limb compartments? 10 Rapid return of muscle strength in patients with myasthenia gravis is achieved with what drug? 11 Adalimumab is a monoclonal antibody directed against what target? 12 Prior to initiating therapy with infliximab patients should be checked for what microbial infection? 13 What types of hypersensitivity reactions are involved in SLE? 14 What autoantibodies are useful in the diagnosis of Sjögren syndrome? 15 What is the most sensitive serologic test for SLE? What is a very specific test for SLE? These question sets are intended to be completed before viewing the High Yield course lectures Video explanations can be found on the Warm-up Questions page within the online High Yield course For further review of the topics covered in this set, refer to the following lectures: Musculoskeletal and Connective Tissue: • Arthritis • Autoimmune and Connective Tissue ...High Yield Warm-up Questions: Musculoskeletal and Connective Tissue, Part B A lesion of the common fibular nerve would result in altered sensation in what regions of the lower limb, and motor weakness... with infliximab patients should be checked for what microbial infection? 13 What types of hypersensitivity reactions are involved in SLE? 14 What autoantibodies are useful in the diagnosis of Sjögren... Sjögren syndrome? 15 What is the most sensitive serologic test for SLE? What is a very specific test for SLE? These question sets are intended to be completed before viewing the High Yield course