General principles GP set 05 immuno heme onc b

High Yield Warm-up Questions: Immunology, Hematology, and Oncology, Part B GENERAL PRINCIPLES SET 5: IMMUNOLOGY, HEMATOLOGY, AND ONCOLOGY, PART B Leucovorin is administered to patients who have been treated with methotrexate to reverse the inhibitory effects of methotrexate on what enzyme? A patient is started on a chemotherapy regimen consisting of cyclophosphamide, doxorubicin, vinblastine, and bleomycin How many drugs in the regimen are cell-cycle specific? What cancer chemotherapy drug is characterized by its ability to allow microtubule formation and then stabilize the spindle in such a way as to prevent its disassembly? What diseases affect synthesis of the heme portion of hemoglobin? What types of processes can cause vitamin B12 deficiency anemia? Hb-Barts is seen in which form of anemia? What diseases affect synthesis of the heme portion of hemoglobin? Name several complement deficiency diseases What two diseases can cause anemia due to parasites infecting erythrocytes? 10 What role does von Willebrand factor play in platelet plug formation? 11 Why does splenectomy lead to high blood platelet counts?                                                1 High Yield Warm-up Questions: Immunology, Hematology, and Oncology, Part B 12 Decreased GpIIb/IIIa is a feature of what disease? 13 The antiplatelet effect of clopidogrel is dependent on its ability to block the binding of what molecule? 14 What drug is useful to rapidly reverse the bleeding complications caused by alteplase? 15 A patient with atrial fibrillation has been on warfarin therapy for several months If the patient begins therapy with clarithromycin for pneumonia what is the anticipated effect on prothrombin time? 16 What common laboratory test measures the intrinsic and common coagulation pathways? 17 The autoantibodies in idiopathic thrombocytopenic purpura are directed against which antigens? 18 What laboratory features can aid diagnosis of disseminated intravascular coagulation? These question sets are intended to be completed before viewing the High Yield course lectures Video explanations can be found on the Warm-up Questions page within the online High Yield course For further review of the topics covered in this set, refer to the following lectures: Immunology, Hematology, Oncology: • DNA Replication and Repair • Antineoplastic and Antimetabolite Drugs • Nonhemolytic Anemia and Porphyria • Hemolytic Anemia and Pathologic Red Blood Cell Forms • The Normal Coagulation Cascade and Platelet Plug • Coagulation and Platelet Disorders   ... Questions: Immunology, Hematology, and Oncology, Part B 12 Decreased GpIIb/IIIa is a feature of what disease? 13 The antiplatelet effect of clopidogrel is dependent on its ability to block the binding... to rapidly reverse the bleeding complications caused by alteplase? 15 A patient with atrial fibrillation has been on warfarin therapy for several months If the patient begins therapy with clarithromycin... anticipated effect on prothrombin time? 16 What common laboratory test measures the intrinsic and common coagulation pathways? 17 The autoantibodies in idiopathic thrombocytopenic purpura are directed