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1 Effect of Admission Time on the Outcomes of Liver Cirrhosis with Acute Upper Gastrointestinal Bleeding

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Hindawi Canadian Journal of Gastroenterology and Hepatology Volume 2018, Article ID 3541365, 14 pages https://doi.org/10.1155/2018/3541365 Clinical Study Effect of Admission Time on the Outcomes of Liver Cirrhosis with Acute Upper Gastrointestinal Bleeding: Regular Hours versus Off-Hours Admission Yingying Li,1,2 Bing Han ,1,2 Hongyu Li ,1 Tingxue Song,1,3 Wenchun Bao,1,3 Ran Wang,1 Zhaohui Bai,1,4 Kexin Zheng,1,2 Qianqian Li,1,5 Xiaozhong Guo ,1 and Xingshun Qi 1 Department of Gastroenterology, General Hospital of Shenyang Military Area, Shenyang, 110840, China Postgraduate College, Jinzhou Medical University, Jinzhou 121001, China Postgraduate College, Liaoning University of Traditional Chinese Medicine, Shenyang, 110840, China Postgraduate College, Shenyang Pharmaceutical University, Shenyang 110840, China Postgraduate College, Dalian Medical University, Dalian 116044, China Correspondence should be addressed to Hongyu Li; 13309887041@163.com, Xiaozhong Guo; guo xiao zhong@126.com, and Xingshun Qi; xingshunqi@126.com Received August 2018; Revised 29 October 2018; Accepted November 2018; Published 29 November 2018 Guest Editor: Eduardo Garcia Vilela Copyright © 2018 Yingying Li et al This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited Background and Aims Acute upper gastrointestinal bleeding (AUGIB) is a lethal complication of liver cirrhosis We aimed to compare the outcomes of patients with liver cirrhosis and AUGIB who were admitted to hospital on regular hours and off-hours Methods This retrospective study screened all cirrhotic patients with AUGIB who were admitted to our hospital from January 2010 to June 2014 for the test cohort and from December 2014 to March 2018 for the validation cohort A 1:1 propensity score matching analysis was performed to adjust the Child-Pugh and MELD scores In-hospital mortality, 5-day rebleeding rate, length of stay, and total payment were primary outcomes Results Overall, 826 and 173 patients with liver cirrhosis and AUGIB were included in the test and validation cohorts, respectively After propensity score matching, 226 and 40 patients were included in the test and validation cohorts, respectively The overall analysis of the test cohort found significantly higher Child-Pugh score (P=0.006), 5-day rebleeding rate (18.69% versus 10.72%, P=0.001), and total payment (¥25,906.83 versus ¥22,017.42, P

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