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Loại |
Chi tiết |
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Biochem Pharmacol |
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| 10. Urasaki, Y.; Laco, G. S.; Pourquier, P.; Takebayashi, Y.; Kohlhagen, G.; Gioffre, C.; Zhang, H. L.; Chatterjee, D.; Pantazis, P.; Pommier, Y.Characterization of a Novel Topoisomerase I Mutation from a Camptothecin- Resistant Human Prostate Cancer Cell Lin. Cancer Res. 2001, 61, 1964– |
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| 11. Fujimori, A.; Harker, W. G.; Kohlhagen, G.; Hoki, Y.; Pommier, Y. Mutation at the Catalytic Site of Topoisomerase I in CEM/C2, a Human Leukemia Cell Resistant to Camptothecin. Cancer Res. 1995, 55, 1339–1346 |
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| 12. Bates, S. E.; Medina-Perez, W. Y.; Kohlhagen, G.; Antony, S.; Nadjem, T.; Robey, R. W.; Pommier, Y. ABCG2Mediates Differential Resistance to SN- 38 (7-Ethyl-10-hydroxycamptothecin) and Homocamptothecins. J Pharmacol Exp Ther. . 2004, 310, 836–842 |
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| 13. Hoki, Y.; Fujimori, A.; Pommier, Y. Differential Cytotoxicity Of Clinically Important Camptothecin Derivatives In P-Glycoprotein Overexpressing Cell Lines. Cancer Chemother Pharmacol. 1997, 40, 433–438 |
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Cancer Chemother Pharmacol |
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| 14. Brangi, M.; Litman, T.; Ciotti, M.; Nishiyama, K.; Kohlhagen, G.; Takimoto, C.; Robey, R.; Pommier, Y.; Fojo, T.; Bates, S. E. Camptothecin Resistance:Role of the ATP-Binding Cassette (ABC), Mitoxantrone-Resistance Half- transporter (MXR), and Potential f. Cancer Res. 1999, 59, 5938–5946 |
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| 15. Antony, S.; Jayaraman, M.; Laco, G.; Kohlhagen, G.; Kohn, K. W.; Cushman, M.; Pommier, Y. Differential Induction of Topoisomerase IDNA Cleavage Complexes by the Indenoisoquinoline MJ-III-65 (NSC 706744) and Camptothecin: Base Sequence Analysis and Activit. Cancer Res. 2003, 63, 7428–7435 |
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| 16. Kohlhagen, G.; Paull, K.; Cushman, M.; Nagafuji, P.; Pommier, Y. Protein- Linked DNA Strand Breaks Induced by NSC 314622, a Novel Noncamptothecin Topoisomerase I Poison. MolPharmacol. 1998, 54, 50–58 |
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| 18. Chrencik, J. E.; Staker, B. L.; Burgin, A. B.; Pourquier, P.; Pommier, Y.; Stewart, L.; Redinbo, M. R. Mechanisms of Camptothecin Resistance by Human Topoisomerase I Mutations. J Mol Biol. 2004, 339, 773–784 |
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| 19. Pommier, Y.; Leo, E.; Zhang, H. L.; Marchand, C. DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs. Chem Biol. 2010, 17, 421–433 |
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| 20. Nagarajan, M.; Morrell, A.; Ioanoviciu, A.; Antony, S.; Kohlhagen, G.; Agama, K.; Hollingshead, M.; Pommier, Y.; Cushman, M. Synthesis and Evaluation of Indenoisoquinoline Topoisomerase I Inhibitors Substituted with Nitrogen Heterocycles. J Med Chem. 2006, 49, 6283–6289 |
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| 21. Geraldine Helen O’Sullivan Coyne, Shivaani Kummar, Robert S. Meehan, Howard Streicher, Naoko Takebe, Elad Sharon. A Phase I Study of Indenoisoquinolines LMP400 and LMP776 in Adults With Relapsed Solid Tumors and Lymphomas. Journal of Clinical Oncology. 2017, 35, 2558 |
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Journal of Clinical Oncology |
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| 22. Pommier, Y.; Cushman, M. The Indenoisoquinoline Noncamptothecin Topoisomerase I Inhibitors: Update and Perspectives. Mol. Cancer Ther.2009, 8, 1008-1014 |
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