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... Effect of aging on PepT1 expression in spontaneously hypertensive rats 72 3.3 Effect of aging on absorption of oligopeptides Gly-Sar-Sar-Sar and GlySar-Sar-Sar-Sar in spontaneously hypertensive rats. .. expressed in the brush border membrane of small intestine, which plays a role in the intestinal absorption of di-/tripeptides PepT1 is composed of 708 amino acids with 12 membranespanning domains Although... absorption of oligopeptides has remained unclear Figure 1-3 Schematic diagram for peptide absorption in intestinal tract 14 According to all of the above-mentioned points, the aim of the present