Molecular and Cell Basis of Inheritance

7th Week, 3rd Semester Molecular and Cell Basis of Inheritance NQH, DDL, HTMN @HUS Announcements The 2nd practical section on genetics starts this week, in R 235, T1 (Dept Genetics) NQH, DDL, HTMN @HUS Overview of today’s topics: Reading: Chapter 14.1 - 5; 19.2 - 4th theme DNA replication and repair The end replication problem and telomerase How cells repair replication mistakes Other types of DNA repair 5th theme Applications of DNA synthesis in Mol Bio How to perform DNA synthesis in test tube (a.k.a PCR) Gel electrophoresis DNA sequencing A genomic revolution 6th theme Meiosis and Genetic Variability Vocabulary of meiosis The process of meiosis Nondisjunction – when good spindles go bad NQH, DDL, HTMN @HUS 4th theme DNA replication and repair NQH, DDL, HTMN @HUS NQH, DDL, HTMN @HUS NQH, DDL, HTMN @HUS NQH, DDL, HTMN @HUS NQH, DDL, HTMN @HUS NQH, DDL, HTMN @HUS NQH, DDL, HTMN @HUS NQH, DDL, HTMN @HUS NQH, DDL, HTMN @HUS NQH, DDL, HTMN @HUS NQH, DDL, HTMN @HUS NQH, DDL, HTMN @HUS NQH, DDL, HTMN @HUS NQH, DDL, HTMN @HUS NQH, DDL, HTMN @HUS Movies of meiosis I in the crane fly NQH, DDL, HTMN @HUS Movies of meiosis II in the crane fly NQH, DDL, HTMN @HUS NQH, DDL, HTMN @HUS NQH, DDL, HTMN @HUS NQH, DDL, HTMN @HUS Questions regarding meiosis & germ cell formation - How sex is determined in human? - What happens when mistakes in meiosis occur (nondisjunction – when chromosomes don’t segregate properly) NQH, DDL, HTMN @HUS MOLECULAR AND CELL BASIS OF INHERITANCE Q&A ... Overview of today’s topics: Reading: Chapter 14.1 - 5; 19.2 - 4th theme DNA replication and repair The end replication problem and telomerase How cells repair replication mistakes Other types of DNA... 5th theme Application of DNA synthesis in molecular biology NQH, DDL, HTMN @HUS If we mix all of these ingredients in the test tube, can we get DNA synthesis outside of the cell? NQH, DDL, HTMN... and Genetic Variability Vocabulary of meiosis The process of meiosis Nondisjunction – when good spindles go bad NQH, DDL, HTMN @HUS 4th theme DNA replication and repair NQH, DDL, HTMN @HUS NQH,