... Distribution of 7 -enolase was altered in chronic liver Figs, i-3, Immunoperoxidase staining for a -enolase {Fig I), 0enolase {Fi}; 2) and 7 -enolase l,Fi,^ 3) in normal liver «-EnoIase is positive in hepatocytes... neighboring these bulging lobules lacked 7-enoIase (Fig 7) The intensity ofthe 7 -enolase staining varied among pseudolobules in cirrhotic livers Control stainings No reaction was observed in the... and eosin staining re- ENOLASE ISOZYMES IN LIVER DISEASE June 1989 603 cytes were generally small and showed a cobblestone arrangement Binucleate cells were sometimes detected in the lobule In contrast,